G:834

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Official Symbol CASP1
Aliases ICE, P45, IL1BC
EntrezGene 834
UniProt Coming Soon
Unique Molecular Interactions 37
Total Molecular Interactions 41
Total Single Events 181
Unique Interaction Partners 23

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to CASP1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to CASP1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to CASP1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT76199 CASP1 Positive_regulation of CEL 1 0.06 0.32 1.14
2 INT91655 SLC8A1 Negative_regulation of CASP1 1 0.02 0.43 0.75
3 INT76200 CASP1 Positive_regulation of Gene_expression of PTGS1 1 0.05 0.16 0.54
4 INT115184 Regulation of CASP1 Positive_regulation of MAPK9 1 0.09 0 0.49
5 INT115183 CASP1 Positive_regulation of Positive_regulation of MAPK9 1 0.16 0 0.48
6 INT115185 CASP1 Positive_regulation of MAPK9 1 0.15 0 0.48
7 INT150393 Binding of CASP1 and MEFV 2 0.16 2.48 0.45
8 INT155086 CASP1 Negative_regulation of DAXX 1 0.21 1.26 0.45
9 INT155085 CASP1 Negative_regulation of CASP8 1 0.29 1.25 0.44
10 INT112800 CASP1 Positive_regulation of Gene_expression of CCL2 1 0.04 0.48 0.43
11 INT91656 SLC8A1 Negative_regulation of Positive_regulation of CASP1 1 0.01 0.2 0.38
12 INT91652 Negative_regulation of SLC8A1 Negative_regulation of CASP1 1 0.02 0.21 0.37
13 INT334879 CASP1 Regulation of IL1B 1 0.03 1.63 0.31
14 INT112797 Positive_regulation of CASP1 Positive_regulation of MAPK1 1 0.02 0.16 0.3
15 INT219151 IL18 Positive_regulation of CASP1 1 0.01 1.05 0.3
16 INT112795 Positive_regulation of CASP1 Positive_regulation of MAPK8 1 0.02 0.16 0.3
17 INT112799 Positive_regulation of CASP1 Positive_regulation of MAPK14 1 0.02 0.16 0.3
18 INT112803 CASP1 Positive_regulation of MAPK8 1 0.02 0.16 0.29
19 INT112805 CASP1 Positive_regulation of MAPK1 1 0.02 0.16 0.29
20 INT116595 CASP1 Positive_regulation of IL6 1 0.07 0.46 0.28
21 INT116591 CASP1 Positive_regulation of PTGER2 1 0.01 0.46 0.28
22 INT322021 Negative_regulation of CASP1 Positive_regulation of IL1B 1 0.04 0.13 0.26
23 INT112794 CASP1 Positive_regulation of MAPK14 1 0.02 0.16 0.23
24 INT112798 CASP1 Positive_regulation of CCL2 1 0.02 0.19 0.21
25 INT91654 Negative_regulation of CASP1 Negative_regulation of IL1B 1 0.46 0.15 0.2
26 INT91653 Negative_regulation of CASP1 Negative_regulation of IL18 1 0.39 0.15 0.2
27 INT279267 Binding of RIPK2 and Positive_regulation of Gene_expression of CASP1 1 0.26 1.12 0.14
28 INT219152 NLRP3 Positive_regulation of Positive_regulation of CASP1 1 0.02 0.83 0.1
29 INT270833 Binding of CASP1 and Panx1 1 0.02 0.14 0.09
30 INT270830 Panx1 Negative_regulation of CASP1 1 0.03 0.09 0.09
31 INT270832 Negative_regulation of Panx1 Negative_regulation of Gene_expression of CASP1 1 0.03 0.14 0.08
32 INT322020 IL1B Regulation of Negative_regulation of CASP1 1 0.03 0 0.08
33 INT244130 Binding of CASP1 and RNGTT 1 0.07 0.24 0.07
34 INT290312 Binding of CASP1 and NCK1 1 0.00 0.29 0.04
35 INT345281 Binding of CASP1 and Nlrp3 1 0.02 0.31 0.03
36 INT345282 Binding of CASP1 and Pycard 1 0.01 0.3 0.03
37 INT279268 CARD8 Positive_regulation of CASP1 1 0.32 0.3 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 834. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 834. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT71174 Gene_expression of CASP1 44 0.75 30.3 9.37
2 INT13406 Negative_regulation of CASP1 25 0.57 10.61 6.36
3 INT81049 Positive_regulation of CASP1 44 0.67 19.97 5.69
4 INT95592 Positive_regulation of Gene_expression of CASP1 15 0.48 13.06 2.1
5 INT71173 Negative_regulation of Gene_expression of CASP1 5 0.36 3.17 1.84
6 INT95338 Positive_regulation of Positive_regulation of CASP1 9 0.49 4.61 1.43
7 INT7817 Binding of CASP1 7 0.19 1.26 1.13
8 INT128496 Regulation of CASP1 5 0.38 3.4 1.09
9 INT91658 Localization of CASP1 5 0.77 0.89 1.04
10 INT128497 Regulation of Gene_expression of CASP1 4 0.38 2.02 0.72
11 INT91661 Negative_regulation of Positive_regulation of CASP1 2 0.41 0.35 0.5
12 INT115195 Negative_regulation of Localization of CASP1 1 0.16 0 0.48
13 INT91665 Positive_regulation of Localization of CASP1 2 0.48 0.27 0.4
14 INT244136 Transcription of CASP1 1 0.39 0.5 0
15 INT270821 Regulation of Positive_regulation of CASP1 1 0.03 0 0
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