GO:0000413

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Name protein peptidyl-prolyl isomerization
Categary Process
Go Slim No
Go Link GO:0000413
Unique Molecular Interactions 54
Total Molecular Interactions 64
Total Single Events 256
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein peptidyl-prolyl isomerization. They are ordered first by their pain relevance and then by number of times they were reported for protein peptidyl-prolyl isomerization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT228680 Fkbp1a Negative_regulation of Trib3 1 0.01 0.56 1.18
2 INT161512 Ppig Negative_regulation of Positive_regulation of S100a8 1 0.02 0.23 1.12
3 INT252602 Binding of Cxcl10 and Ppig 1 0.08 1.55 0.96
4 INT252603 Ppig Positive_regulation of Gene_expression of Cx3cl1 1 0.10 1.8 0.69
5 INT252605 Ppig Positive_regulation of Gene_expression of Cx3cr1 1 0.09 1.81 0.69
6 INT77098 Nlrp1a Negative_regulation of Positive_regulation of Ppig 1 0.47 0.68 0.53
7 INT326303 Binding of CRP and FKBP4 1 0.15 1.22 0.41
8 INT304340 FKBP5 Regulation of NR3C1 1 0.05 0.71 0.37
9 INT202810 Pin1 Regulation of Csf2 1 0.03 0.82 0.36
10 INT202808 Binding of Pin1 and Hnrpd 1 0.08 0.84 0.22
11 INT252600 Ppig Regulation of Hand1 1 0.06 0.43 0.17
12 INT252598 Ppig Regulation of Gene_expression of Hand1 1 0.06 0.43 0.17
13 INT56010 Binding of FN1 and FKBPL 1 0.00 0.54 0.15
14 INT202813 Pin1 Positive_regulation of Regulation of TH1L 1 0.50 0 0.14
15 INT207776 Binding of FKBP1A and RYR1 1 0.05 0.59 0.12
16 INT202807 Pin1 Regulation of Binding of Hnrpd 1 0.06 0.14 0.08
17 INT262209 Positive_regulation of Nr1i2 Positive_regulation of Transcription of Ppig 1 0.03 0 0.06
18 INT293360 Binding of CSH1 and FKBP1A 1 0.00 0.14 0.05
19 INT207760 Fkbp1a Regulation of MSMB 1 0.12 0.69 0.04
20 INT199406 Binding of CYP3A4 and PPIB 1 0.40 0 0.04
21 INT293358 Binding of FKBP1A and CABIN1 1 0.00 0.07 0.03
22 INT221243 Binding of Hspa9 and Ppif 1 0.01 0.67 0.03
23 INT265231 Binding of FKBP1A and TGFBR1 1 0.11 0.35 0
24 INT293355 Binding of Fkbp1a and CABIN1 1 0.00 0.12 0
25 INT273116 Binding of Fkbp1a and Mtor 1 0.37 0 0
26 INT307155 Char1 Regulation of Ppig 1 0.00 0.92 0
27 INT307160 Regulation of Binding of Cyp2a5 and Ppig 1 0.05 1.22 0
28 INT307159 Cyp2a5 Regulation of Ppig 1 0.03 0.91 0
29 INT293354 Binding of CSH1 and Fkbp1a 1 0.00 0.12 0
30 INT265233 Binding of APC and FKBP1A 1 0.08 0.41 0
31 INT265234 Binding of FKBP1A and SGCG 1 0.03 0.35 0
32 INT293366 Binding of CABIN1 and Fkbp1a 1 0.00 0.05 0
33 INT265232 Regulation of Binding of APC and FKBP1A 1 0.08 0.41 0
34 INT271999 Binding of Fkbp1a and Positive_regulation of Negative_regulation of Mtor 1 0.00 0.18 0
35 INT190681 Binding of Bcl2 and Fkbp1a 1 0.01 0.46 0
36 INT271994 Binding of Fkbp1a and Mtor 1 0.00 0.22 0
37 INT307158 Binding of Cyp2a5 and Ppig 1 0.04 1.22 0
38 INT351095 Binding of FKBP1A and RPS6KB1 1 0.24 0.36 0
39 INT351101 Negative_regulation of Binding of FKBP1A and RPS6KB1 1 0.27 0.36 0
40 INT260264 Binding of MTOR and FKBP7 1 0.26 0.87 0
41 INT351096 Binding of FKBP1A and MTOR 1 0.28 1.35 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein peptidyl-prolyl isomerization. They are ordered first by their pain relevance and then by number of times they were reported in protein peptidyl-prolyl isomerization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT127037 Gene_expression of Ppig 26 0.65 16.08 6.84
2 INT77076 Positive_regulation of Ppig 16 0.49 13.54 5.91
3 INT60575 Binding of Fkbp1a 9 0.26 2.09 4.46
4 INT127039 Negative_regulation of Ppig 13 0.21 5.29 3.87
5 INT202792 Negative_regulation of Pin1 1 0.56 3.77 2.37
6 INT149975 Negative_regulation of Ppif 1 0.41 0.44 2.36
7 INT112418 Gene_expression of FKBP5 3 0.43 1.97 1.62
8 INT112420 Negative_regulation of Gene_expression of FKBP5 1 0.16 0.85 1.42
9 INT252582 Positive_regulation of Gene_expression of Ppig 3 0.12 2.62 1.13
10 INT230251 Binding of FKBP1A 6 0.28 2.24 0.94
11 INT163995 Negative_regulation of Gene_expression of Ppig 4 0.24 2.07 0.89
12 INT202790 Binding of Pin1 1 0.46 3.02 0.88
13 INT202786 Regulation of Pin1 1 0.43 2.16 0.83
14 INT100542 Regulation of Ppig 6 0.17 11.78 0.69
15 INT157849 Negative_regulation of FKBP5 1 0.32 1.72 0.69
16 INT202806 Gene_expression of Pin1 1 0.74 1.87 0.66
17 INT196866 Localization of Ppig 2 0.17 0.58 0.64
18 INT304344 Positive_regulation of FKBP5 1 0.41 1.36 0.64
19 INT103782 Binding of Ppig 5 0.12 2.57 0.58
20 INT157848 Regulation of FKBP5 1 0.34 1.74 0.53
21 INT202801 Positive_regulation of Pin1 1 0.67 1.37 0.52
22 INT279363 Binding of FKBP4 1 0.05 0.22 0.49
23 INT307141 Regulation of Gene_expression of Ppig 3 0.08 1.84 0.43
24 INT202805 Negative_regulation of Negative_regulation of Pin1 1 0.41 0.77 0.43
25 INT207064 Gene_expression of Fkbp1a 2 0.32 1.52 0.34
26 INT252595 Regulation of Negative_regulation of Ppig 1 0.12 0.78 0.34
27 INT252581 Positive_regulation of Positive_regulation of Ppig 1 0.11 1.26 0.34
28 INT157850 Positive_regulation of Negative_regulation of FKBP5 1 0.37 0.87 0.34
29 INT304343 Positive_regulation of Positive_regulation of FKBP5 1 0.41 0.68 0.33
30 INT207065 Localization of Fkbp1a 1 0.36 0.82 0.33
31 INT190676 Binding of Fkbp1a 15 0.36 3.11 0.28
32 INT202802 Regulation of Fkbp1a 4 0.26 0.96 0.28
33 INT202791 Phosphorylation of Pin1 1 0.78 0.61 0.28
34 INT202789 Positive_regulation of Gene_expression of Pin1 1 0.67 0.62 0.22
35 INT164519 Gene_expression of FKBP1A 2 0.39 0.22 0.19
36 INT307151 Negative_regulation of Positive_regulation of Ppig 1 0.07 1.02 0.19
37 INT307138 Positive_regulation of Negative_regulation of Ppig 2 0.06 1.01 0.18
38 INT252583 Positive_regulation of Binding of Ppig 1 0.12 0.46 0.16
39 INT202796 Regulation of Negative_regulation of Pin1 1 0.59 0.23 0.15
40 INT202797 Negative_regulation of Binding of Pin1 1 0.41 0.74 0.15
41 INT307142 Regulation of Positive_regulation of Ppig 1 0.03 0.98 0.15
42 INT293345 Negative_regulation of Binding of FKBP1A 1 0.02 0.19 0.13
43 INT56013 Binding of FKBPL 1 0.00 0.54 0.12
44 INT202794 Negative_regulation of Protein_catabolism of Pin1 1 0.41 0.15 0.11
45 INT202793 Protein_catabolism of Pin1 1 0.63 0.15 0.11
46 INT299319 Localization of FKBP1A 1 0.44 0 0.09
47 INT307154 Negative_regulation of Negative_regulation of Ppig 1 0.06 0.47 0.08
48 INT199785 Transcription of Ppig 2 0.15 0.6 0.06
49 INT262035 Positive_regulation of Transcription of Ppig 1 0.03 0.05 0.06
50 INT197045 Gene_expression of PPIB 6 0.70 2.32 0.05
51 INT299313 Positive_regulation of Gene_expression of FKBP1A 1 0.29 0 0.05
52 INT331765 Protein_catabolism of Ppig 1 0.13 0.06 0.03
53 INT199412 Positive_regulation of PPIB 2 0.49 0.09 0
54 INT260277 Gene_expression of FKBP7 1 0.55 0.14 0
55 INT217254 Binding of PPIB 1 0.36 0 0
56 INT235550 Regulation of Ppif 1 0.10 0.09 0
57 INT260283 Binding of FKBP7 1 0.34 0 0
58 INT217250 Negative_regulation of Positive_regulation of PPIB 1 0.41 0 0
59 INT199781 Regulation of Regulation of Ppig 1 0.07 1.14 0
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