GO:0000980

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Name RNA polymerase II distal enhancer sequence-specific DNA binding
Categary Function
Go Slim No
Go Link GO:0000980
Unique Molecular Interactions 630
Total Molecular Interactions 904
Total Single Events 6031
Pain Genes Associated 23

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for RNA polymerase II distal enhancer sequence-specific DNA binding. They are ordered first by their pain relevance and then by number of times they were reported for RNA polymerase II distal enhancer sequence-specific DNA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 2 0.27 0.43 3.88
2 INT17317 Binding of Jun and Fos 7 0.42 1.03 3.5
3 INT161164 Prkcg Regulation of Phosphorylation of Creb1 3 0.41 0.62 3.11
4 INT309150 Edc4 Positive_regulation of Creb1 1 0.03 3.46 3.09
5 INT190167 Binding of JUN and MMP12 1 0.26 0.82 2.76
6 INT54489 Binding of Jun and Rabep2 4 0.16 1.48 2.3
7 INT156622 Umod Regulation of Phosphorylation of Creb1 1 0.05 0.33 2.27
8 INT158964 FosB Negative_regulation of Creb1 1 0.21 0 2.07
9 INT114927 Positive_regulation of Binding of Oprm1 and Creb1 1 0.17 0.28 2.07
10 INT114923 Binding of Oprm1 and Creb1 1 0.16 0.28 2.06
11 INT124133 Camk2a Regulation of Phosphorylation of Creb1 1 0.46 0 2
12 INT54488 Npepo Regulation of Gene_expression of Jun 1 0.30 0 1.98
13 INT186435 Prkcg Regulation of Creb1 1 0.44 0.45 1.9
14 INT186432 Prkaca Regulation of Creb1 1 0.14 0.45 1.9
15 INT139640 Jun Regulation of Gene_expression of Npy 1 0.21 1.98 1.75
16 INT186433 Trib3 Regulation of Phosphorylation of Creb1 1 0.03 0.32 1.71
17 INT105112 Plat Positive_regulation of JUN 1 0.01 1.55 1.58
18 INT131574 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Creb1 1 0.41 0.33 1.58
19 INT114926 Creb1 Negative_regulation of Positive_regulation of Oprm1 1 0.13 0.23 1.56
20 INT79021 Regulation of Binding of Jun and Fos 2 0.50 0.66 1.5
21 INT121747 Prkcg Negative_regulation of Positive_regulation of Creb1 1 0.16 0.2 1.5
22 INT121741 Prkaca Negative_regulation of Positive_regulation of Creb1 1 0.10 0.2 1.49
23 INT298283 Pou4f1 Positive_regulation of Gene_expression of Runx1 1 0.50 1.4 1.48
24 INT73650 Binding of Pim3 and Creb1 1 0.03 2.48 1.47
25 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38
26 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37
27 INT106850 P2ry2 Positive_regulation of Phosphorylation of Creb1 2 0.49 0.73 1.36
28 INT168722 Creb1 Positive_regulation of Calca 1 0.73 1.05 1.35
29 INT131886 Creb1 Positive_regulation of Gene_expression of Prkcg 1 0.03 0 1.31
30 INT124767 Creb1 Regulation of Oprm1 1 0.45 0 1.26
31 INT287104 Binding of Ntrk2 and T 1 0.20 3.29 1.26
32 INT136250 Phosphorylation of Tff3 Regulation of Creb1 1 0.02 0.18 1.24
33 INT136256 Creb1 Regulation of SGCG 1 0.26 0.18 1.23
34 INT136258 Creb1 Regulation of GRIA1 1 0.26 0.18 1.23
35 INT131195 Creb1 Positive_regulation of Positive_regulation of Drd1a 2 0.27 0.61 1.22
36 INT256298 Binding of Creb1 and Ephb1 1 0.16 1.27 1.22
37 INT298260 Binding of Runx3 and Pou4f1 1 0.52 2.08 1.22
38 INT256297 Binding of Creb1 and Insrr 1 0.00 1.22 1.19
39 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19
40 INT124435 Gene_expression of Chrna9 Positive_regulation of Phosphorylation of Creb1 1 0.11 0.6 1.17
41 INT105423 Jun Positive_regulation of Gene_expression of Penk 1 0.43 0 1.09
42 INT156462 Creb1 Regulation of Ephb1 1 0.29 0 1.07
43 INT105109 Cxcl12 Positive_regulation of JUN 1 0.01 1.07 1.05
44 INT119888 Binding of Creb1 and Usf1 1 0.18 0.15 1.05
45 INT95378 Binding of Jun and Jund 5 0.20 2.06 1.02
46 INT74027 Creb1 Regulation of Jun 4 0.27 1.04 1.02
47 INT101065 MAP3K15 Positive_regulation of JUN 1 0.43 0.46 1.02
48 INT139636 Jun Negative_regulation of Phosphorylation of Npy 1 0.33 1.07 1.01
49 INT113453 Ngf Positive_regulation of JUN 1 0.27 0.6 1.01
50 INT139639 Jun Negative_regulation of Positive_regulation of Vip 1 0.53 1.07 1
51 INT139643 Jun Negative_regulation of Positive_regulation of Npy 1 0.33 1.07 1
52 INT83987 Ngf Regulation of Atf2 1 0.52 0.49 1
53 INT139641 Positive_regulation of Jun Positive_regulation of Positive_regulation of Vip 1 0.37 0.95 0.99
54 INT139642 Positive_regulation of Jun Regulation of Gene_expression of Npy 1 0.21 1.07 0.97
55 INT139638 Positive_regulation of Jun Positive_regulation of Positive_regulation of Npy 1 0.36 1.18 0.96
56 INT127263 Adra2a Regulation of Gene_expression of Jun 1 0.07 1.1 0.95
57 INT152390 Negative_regulation of Binding of JUN and OPRM1 1 0.13 0.14 0.94
58 INT152387 Binding of JUN and OPRM1 1 0.15 0.14 0.94
59 INT186431 Trib3 Regulation of Creb1 1 0.03 0.23 0.92
60 INT151263 Jun Positive_regulation of S100a8 1 0.00 0.95 0.92
61 INT128860 NR1H4 Negative_regulation of Gene_expression of OPRM1 1 0.15 0.31 0.92
62 INT252879 Creb1 Positive_regulation of Gene_expression of Tacr1 1 0.03 0.24 0.91
63 INT219037 Creb1 Positive_regulation of Transcription of Bdnf 2 0.43 1.07 0.9
64 INT77253 Binding of gr and Creb1 1 0.03 0.4 0.9
65 INT309140 Dlat Positive_regulation of Creb1 1 0.06 1.1 0.9
66 INT249347 Binding of FOS and JUN 4 0.19 6.15 0.89
67 INT142128 Nrgn Regulation of Creb1 1 0.38 0.25 0.89
68 INT73653 Binding of Creb1 and Fos 1 0.40 1.49 0.87
69 INT161308 POMC Negative_regulation of Positive_regulation of JUN 1 0.12 0.27 0.86
70 INT161307 JUN Positive_regulation of IL2 1 0.14 0.25 0.84
71 INT304575 Creb1 Regulation of Gene_expression of Bdnf 1 0.04 1 0.84
72 INT271193 Creb1 Regulation of Bdnf 1 0.15 0.28 0.81
73 INT298279 Pou4f1 Positive_regulation of Gene_expression of Runx3 1 0.50 1.31 0.81
74 INT190182 JUN Positive_regulation of MMP12 1 0.34 0.08 0.8
75 INT109142 Calca Positive_regulation of Transcription of Creb1 1 0.47 0.13 0.8
76 INT182839 Camk4 Positive_regulation of Creb1 3 0.49 1.81 0.79
77 INT114924 Creb1 Regulation of Positive_regulation of Oprm1 1 0.09 0.13 0.79
78 INT186439 Prkaca Regulation of Phosphorylation of Creb1 1 0.06 0.08 0.79
79 INT131194 Creb1 Positive_regulation of Gene_expression of Pdyn 1 0.26 0.08 0.79
80 INT151807 Binding of NFATC1 and OPRM1 1 0.19 0 0.79
81 INT302831 Binding of Creb1 and Mapkapk5 1 0.07 1.3 0.79
82 INT200094 Negative_regulation of Jun Negative_regulation of Gene_expression of Ptgs2 1 0.01 2.87 0.78
83 INT224280 Bdnf Positive_regulation of Creb1 3 0.30 0.62 0.77
84 INT261413 Positive_regulation of GRIN1 Positive_regulation of Positive_regulation of Creb1 1 0.00 0.81 0.77
85 INT200097 Negative_regulation of Binding of Il1a and Jun 1 0.00 2.76 0.77
86 INT90120 Jun Positive_regulation of Gene_expression of Nos1 1 0.38 0.39 0.76
87 INT106335 Olr1254 Positive_regulation of Phosphorylation of Creb1 1 0.03 0 0.76
88 INT90118 Jun Regulation of Gene_expression of Nfkb1 1 0.18 0.39 0.76
89 INT109141 Calca Positive_regulation of Creb1 1 0.47 0.13 0.76
90 INT151808 NFATC1 Positive_regulation of Positive_regulation of OPRM1 1 0.20 0 0.76
91 INT90117 Jun Regulation of Gene_expression of Nos1 1 0.21 0.39 0.76
92 INT200093 Binding of Il1a and Jun 1 0.00 2.64 0.76
93 INT90123 Jun Positive_regulation of Gene_expression of Fos 1 0.47 0.39 0.76
94 INT109143 Calca Positive_regulation of Phosphorylation of Creb1 1 0.47 0.13 0.76
95 INT151809 JUN Positive_regulation of Positive_regulation of OPRM1 1 0.32 0 0.74
96 INT168420 Positive_regulation of Mapk8 Positive_regulation of Phosphorylation of Jun 1 0.30 0.88 0.74
97 INT190169 Regulation of JUN Positive_regulation of Localization of MMP12 1 0.30 0.07 0.74
98 INT106527 Akt1 Positive_regulation of Jun 1 0.05 0.53 0.74
99 INT186436 Phosphorylation of Creb1 Regulation of Transcription of Jun 1 0.21 0.44 0.73
100 INT186445 Creb1 Regulation of Transcription of FOS 1 0.49 0.44 0.73
101 INT186443 Phosphorylation of Creb1 Regulation of Transcription of FOS 1 0.49 0.44 0.73
102 INT186438 Creb1 Regulation of Transcription of Jun 1 0.21 0.44 0.73
103 INT186444 Creb1 Regulation of FOS 1 0.49 0.43 0.72
104 INT253828 Creb1 Positive_regulation of Gene_expression of Cartpt 1 0.19 0.15 0.72
105 INT186442 Phosphorylation of Creb1 Regulation of FOS 1 0.49 0.43 0.72
106 INT186440 Phosphorylation of Creb1 Regulation of Jun 1 0.21 0.43 0.72
107 INT207540 Tfap2a Regulation of Oprm1 1 0.13 0.06 0.7
108 INT123300 Mks1 Positive_regulation of Creb1 1 0.01 0.35 0.7
109 INT287099 Binding of Bdnf and T 1 0.10 1.1 0.69
110 INT135207 Gmeb1 Regulation of Gene_expression of Tfap2a 1 0.07 0.48 0.69
111 INT135206 Ighen Regulation of Gene_expression of Tfap2a 1 0.06 0.48 0.69
112 INT66581 Binding of JUN and Rare2 1 0.00 0.07 0.69
113 INT135202 Tfap2a Regulation of Gene_expression of Ighen 1 0.06 0.48 0.69
114 INT135213 Tfap2a Regulation of Gene_expression of Nfkb1 1 0.02 0.48 0.69
115 INT135211 Nfkb1 Regulation of Gene_expression of Tfap2a 1 0.02 0.48 0.69
116 INT135204 Tfap2a Regulation of Gene_expression of Gmeb1 1 0.10 0.48 0.69
117 INT223868 Mapk1 Positive_regulation of Creb1 2 0.17 0.34 0.68
118 INT124257 Plat Positive_regulation of Jun 5 0.12 3.33 0.67
119 INT207543 Tfap2a Regulation of Qsox1 1 0.04 0.06 0.67
120 INT92025 Egr1 Positive_regulation of Jun 1 0.15 0.61 0.67
121 INT111555 Negative_regulation of Npr1 Negative_regulation of Positive_regulation of Creb1 1 0.02 0.58 0.66
122 INT110458 Binding of Atf2 and Mapk8 1 0.35 0 0.66
123 INT266064 Binding of PAG1 and Creb1 1 0.04 1.52 0.65
124 INT266049 Binding of Ceacam3 and Creb1 1 0.14 1.53 0.65
125 INT235881 Prkaca Positive_regulation of Creb1 2 0.10 0.16 0.64
126 INT298262 Pou4f1 Positive_regulation of Positive_regulation of Ntrk3 1 0.36 0.79 0.63
127 INT266047 Creb1 Regulation of Ceacam3 1 0.20 1.15 0.62
128 INT186429 Camk2a Regulation of Regulation of Creb1 1 0.09 0.09 0.62
129 INT121873 Creb1 Regulation of Phosphorylation of Car2 1 0.10 0 0.62
130 INT128869 Gabrg1 Positive_regulation of Transcription of Jun 1 0.09 0.55 0.62
131 INT54487 Rabep2 Regulation of Gene_expression of Jun 1 0.06 0 0.61
132 INT123301 Car2 Positive_regulation of Creb1 1 0.21 0.28 0.61
133 INT113962 OPRM1 Regulation of CREB1 1 0.39 0.31 0.6
134 INT98725 Msr1 Positive_regulation of Gene_expression of Creb1 1 0.00 0.09 0.6
135 INT178437 Mapk8 Positive_regulation of Jun 3 0.40 2.69 0.58
136 INT73654 Binding of Jun and Pim3 1 0.02 0.99 0.58
137 INT186434 Trib3 Positive_regulation of Phosphorylation of Creb1 1 0.05 0.26 0.58
138 INT177269 Binding of CXADR and NR1H4 1 0.04 0 0.58
139 INT93063 Binding of gr and Jun 3 0.14 0.79 0.57
140 INT317639 Igf1 Regulation of Creb1 1 0.23 0.16 0.57
141 INT317637 Ngf Regulation of Creb1 1 0.10 0.11 0.57
142 INT90115 Ntrk2 Regulation of Jun 1 0.01 0.27 0.57
143 INT92974 Creb1 Regulation of Positive_regulation of Galr1 1 0.32 0 0.57
144 INT305744 Fst Positive_regulation of Creb1 1 0.12 0.33 0.57
145 INT305732 Tst Positive_regulation of Creb1 1 0.12 0.33 0.57
146 INT73656 Creb1 Positive_regulation of Transcription of Pdyn 1 0.42 0.97 0.56
147 INT296169 Binding of Htr4 and Creb1 1 0.49 0.1 0.56
148 INT296293 Prkaca Regulation of Positive_regulation of Creb1 1 0.16 0.62 0.55
149 INT105424 Creb1 Positive_regulation of Gene_expression of Penk 1 0.49 0 0.55
150 INT114928 Positive_regulation of Creb1 Positive_regulation of Positive_regulation of Oprm1 1 0.16 0.05 0.54
151 INT271902 Binding of KCNK1 and Jun 1 0.12 0.08 0.53
152 INT305738 Binding of Creb1 and Atf6b 1 0.08 0.34 0.53
153 INT335291 SLC15A4 Negative_regulation of NFATC1 1 0.01 0.45 0.51
154 INT244028 Positive_regulation of Binding of Cacnb3 and Tfap2a 1 0.01 0.24 0.49
155 INT244037 Positive_regulation of Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
156 INT219038 Creb1 Regulation of Gene_expression of Bdnf 1 0.25 0.25 0.49
157 INT244000 Positive_regulation of Binding of Tfap2a and Dnm1 1 0.04 0.24 0.49
158 INT244035 Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
159 INT243997 Binding of Tfap2a and Dnm1 1 0.03 0.24 0.49
160 INT244060 Binding of Cacnb3 and Tfap2a 1 0.00 0.24 0.49
161 INT319718 Binding of Crebbp and Creb1 1 0.10 1.68 0.48
162 INT305735 Binding of Bdnf and Creb1 1 0.08 0.49 0.47
163 INT305746 Positive_regulation of Creb1 Positive_regulation of BDNF 1 0.32 0.41 0.47
164 INT305743 Binding of Bdnf and Positive_regulation of Positive_regulation of Creb1 1 0.11 0.49 0.47
165 INT235882 Creb1 Positive_regulation of Positive_regulation of Bdnf 1 0.11 0.17 0.47
166 INT117703 OPRK1 Positive_regulation of Positive_regulation of JUN 1 0.01 0.08 0.47
167 INT142826 UPF1 Positive_regulation of CREB1 1 0.11 0 0.46
168 INT305736 Positive_regulation of Creb1 Positive_regulation of Bdnf 1 0.10 0.41 0.46
169 INT317640 Slc3a1 Positive_regulation of Creb1 1 0.12 0.58 0.46
170 INT116928 PTK2 Positive_regulation of JUN 1 0.20 0.15 0.46
171 INT116933 SRC Positive_regulation of JUN 1 0.33 0.15 0.46
172 INT116929 OPRK1 Positive_regulation of JUN 1 0.28 0.15 0.46
173 INT161162 Creb1 Regulation of Nts 1 0.19 0.15 0.45
174 INT349853 Binding of Hspb1 and Jun 1 0.14 2.3 0.45
175 INT259208 Ca2 Positive_regulation of Phosphorylation of Creb1 1 0.04 0 0.45
176 INT317636 Creb1 Positive_regulation of Phosphorylation of Hmmr 1 0.04 0.55 0.45
177 INT283731 Trib3 Positive_regulation of Creb1 2 0.01 0.16 0.44
178 INT247639 Binding of Jun and Atf3 2 0.09 3.06 0.44
179 INT151782 Phosphorylation of Creb1 Positive_regulation of Gene_expression of P2rx1 1 0.41 0.07 0.44
180 INT321293 Binding of Nr1h4 and Nr0b2 1 0.18 0.31 0.43
181 INT103132 Positive_regulation of DCSTAMP Positive_regulation of JUN 1 0.03 0.73 0.43
182 INT189197 RASGRP1 Positive_regulation of JUN 1 0.07 1.26 0.43
183 INT309113 Edc4 Positive_regulation of Gene_expression of Creb1 1 0.03 0.45 0.43
184 INT127074 Gdnf Regulation of Gene_expression of Jun 1 0.10 0.28 0.43
185 INT106333 Olr1254 Positive_regulation of Creb1 1 0.02 0 0.43
186 INT127075 Bdnf Regulation of Gene_expression of Jun 1 0.11 0.28 0.43
187 INT298263 Pou4f1 Regulation of Gene_expression of Ntrk1 1 0.34 0.61 0.43
188 INT103129 DCSTAMP Positive_regulation of JUN 1 0.03 0.72 0.43
189 INT309145 Positive_regulation of Edc4 Positive_regulation of Creb1 1 0.02 0.35 0.42
190 INT116936 Positive_regulation of GLI2 Positive_regulation of JUN 1 0.12 0.07 0.41
191 INT186148 Camk4 Positive_regulation of Phosphorylation of Creb1 2 0.50 1.11 0.4
192 INT108197 AKT1 Regulation of JUN 1 0.29 0.25 0.4
193 INT235868 Creb1 Negative_regulation of Atf6b 1 0.02 0.21 0.4
194 INT298259 Pou4f1 Negative_regulation of Gene_expression of Runx3 1 0.46 0.58 0.4
195 INT298261 Pou4f1 Negative_regulation of Gene_expression of Runx1 1 0.45 0.58 0.4
196 INT302825 Binding of Creb1 and Xpnpep1 1 0.00 0.64 0.39
197 INT204793 T Positive_regulation of Mthfd1 1 0.00 1.32 0.39
198 INT354820 Creb1 Negative_regulation of Transcription of Cpox 1 0.03 0.59 0.38
199 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38
200 INT97404 Nfkb1 Positive_regulation of Transcription of JUN 1 0.00 1.03 0.38

Single Events

The table below shows the top 100 pain related interactions that have been reported for RNA polymerase II distal enhancer sequence-specific DNA binding. They are ordered first by their pain relevance and then by number of times they were reported in RNA polymerase II distal enhancer sequence-specific DNA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11009 Phosphorylation of Creb1 458 0.82 111.34 221.97
2 INT11012 Positive_regulation of Creb1 258 0.70 84.4 132
3 INT11011 Positive_regulation of Phosphorylation of Creb1 190 0.70 49.25 112.01
4 INT49651 Gene_expression of Creb1 276 0.78 114.77 111.96
5 INT57380 Phosphorylation of Creb1 213 0.82 66.8 71.26
6 INT9484 Gene_expression of Jun 175 0.78 34.89 68.54
7 INT102020 Gene_expression of Creb1 190 0.78 57.31 59.77
8 INT82055 Positive_regulation of Creb1 176 0.70 60.2 58.39
9 INT6796 Positive_regulation of Jun 165 0.70 37.18 49.64
10 INT88617 Positive_regulation of Gene_expression of Creb1 90 0.69 51.69 44.29
11 INT11013 Negative_regulation of Phosphorylation of Creb1 55 0.59 18.74 34.66
12 INT666 Gene_expression of Jun 124 0.78 54.61 33.67
13 INT16714 Regulation of Creb1 64 0.62 22.23 33.56
14 INT47764 Binding of Jun 106 0.48 22.62 31.39
15 INT57379 Positive_regulation of Phosphorylation of Creb1 79 0.69 28.24 30.25
16 INT6660 Positive_regulation of Jun 148 0.69 67.58 29.73
17 INT11010 Regulation of Phosphorylation of Creb1 52 0.62 7.26 29.04
18 INT17331 Positive_regulation of JUN 132 0.69 60.4 27.03
19 INT11014 Phosphorylation of CREB1 72 0.81 26.35 25.64
20 INT102021 Positive_regulation of Gene_expression of Creb1 66 0.70 24.04 23.28
21 INT61160 Negative_regulation of Gene_expression of Creb1 37 0.59 17.95 23.17
22 INT106175 Positive_regulation of Positive_regulation of Creb1 37 0.70 13.89 22.46
23 INT61159 Regulation of Gene_expression of Creb1 46 0.62 24.07 20.52
24 INT9482 Positive_regulation of Gene_expression of Jun 60 0.69 9.95 18.61
25 INT62577 Negative_regulation of Creb1 55 0.59 19.68 18.1
26 INT61158 Negative_regulation of Creb1 33 0.59 11.54 18.06
27 INT102023 Regulation of Creb1 51 0.62 16.29 16.71
28 INT60197 Gene_expression of JUN 90 0.78 42.32 14.61
29 INT17593 Regulation of Jun 37 0.60 5.5 14.35
30 INT107248 Negative_regulation of Gene_expression of Creb1 26 0.58 9.24 13.41
31 INT6794 Negative_regulation of Jun 37 0.53 8.04 13.37
32 INT16713 Binding of Creb1 53 0.48 20.24 13.06
33 INT15756 Positive_regulation of Gene_expression of Jun 29 0.69 16.58 12.06
34 INT203473 Gene_expression of Pou4f1 69 0.76 25.94 11.36
35 INT52233 Transcription of Jun 37 0.66 6.39 11.15
36 INT15597 Negative_regulation of Gene_expression of Jun 20 0.48 6.04 11.08
37 INT62576 Transcription of Creb1 34 0.69 16.97 10.6
38 INT109280 Negative_regulation of Phosphorylation of Creb1 29 0.59 11.81 10.37
39 INT60198 Binding of JUN 54 0.48 11.56 10.27
40 INT54588 Positive_regulation of CREB1 38 0.67 12.01 9.18
41 INT109279 Regulation of Phosphorylation of Creb1 14 0.62 4.06 8.96
42 INT61264 Regulation of Jun 36 0.61 18.42 8.71
43 INT64815 Binding of Jun 49 0.48 21.47 8.59
44 INT93673 Transcription of Creb1 19 0.66 9.27 8.26
45 INT53975 Positive_regulation of Binding of Jun 28 0.70 4.67 8.16
46 INT87271 Positive_regulation of Phosphorylation of CREB1 27 0.66 12.87 7.91
47 INT64816 Transcription of Jun 31 0.69 16.01 7.64
48 INT9476 Regulation of Gene_expression of Jun 14 0.43 4.25 7.61
49 INT10344 Localization of Jun 23 0.73 6.36 7.46
50 INT116619 Positive_regulation of Positive_regulation of Creb1 25 0.69 8.32 7.3
51 INT86867 Regulation of CREB1 15 0.46 4.95 7.28
52 INT75497 Regulation of JUN 28 0.61 11.04 7.09
53 INT106330 Regulation of Positive_regulation of Creb1 11 0.56 5.57 7.06
54 INT53491 Negative_regulation of Jun 28 0.57 14.2 6.9
55 INT47817 Positive_regulation of Positive_regulation of Jun 21 0.66 3.7 6.83
56 INT114642 Negative_regulation of Positive_regulation of Creb1 12 0.57 2.32 6.75
57 INT68653 Negative_regulation of JUN 34 0.58 14.27 6.56
58 INT47765 Negative_regulation of Binding of Jun 21 0.43 5.05 6.38
59 INT92971 Binding of Creb1 31 0.47 11.3 6.22
60 INT105215 Negative_regulation of Pou4f1 16 0.53 9.42 5.97
61 INT73649 Phosphorylation of Jun 28 0.80 11.01 5.87
62 INT6667 Gene_expression of CREB1 27 0.77 6.29 5.84
63 INT88286 Phosphorylation of Atf2 11 0.66 1.93 5.69
64 INT61986 Localization of Creb1 16 0.69 2.12 5.66
65 INT93484 Negative_regulation of Positive_regulation of Jun 30 0.58 9.31 5.18
66 INT102019 Regulation of Gene_expression of Creb1 14 0.61 5.27 5.08
67 INT102202 Negative_regulation of Positive_regulation of Creb1 11 0.58 4.55 4.99
68 INT88282 Positive_regulation of Phosphorylation of Atf2 8 0.44 1.77 4.85
69 INT203506 Positive_regulation of Pou4f1 3 0.49 6.17 4.85
70 INT106524 Phosphorylation of Jun 23 0.80 15.35 4.78
71 INT204449 Gene_expression of T 17 0.32 9.77 4.77
72 INT121866 Localization of Creb1 13 0.73 1.95 4.48
73 INT67936 Transcription of JUN 18 0.52 9.52 4.13
74 INT64163 Negative_regulation of Gene_expression of Jun 13 0.58 3.86 4.03
75 INT6661 Positive_regulation of Positive_regulation of Jun 31 0.50 7.12 3.89
76 INT105217 Regulation of Pou4f1 8 0.60 6.15 3.88
77 INT110180 Phosphorylation of JUN 23 0.80 11.21 3.83
78 INT64817 Positive_regulation of Binding of Jun 16 0.69 6.78 3.81
79 INT15776 Localization of Jun 10 0.74 3.9 3.69
80 INT77251 Positive_regulation of Atf2 8 0.70 2.45 3.62
81 INT61570 Positive_regulation of Transcription of Jun 10 0.35 1.62 3.45
82 INT81453 Positive_regulation of Gene_expression of JUN 18 0.50 9.39 3.23
83 INT70387 Negative_regulation of Positive_regulation of Jun 14 0.37 3.76 3.23
84 INT11015 Regulation of Phosphorylation of CREB1 4 0.46 1.45 3.17
85 INT68651 Negative_regulation of Positive_regulation of JUN 11 0.58 4.28 3.04
86 INT111554 Positive_regulation of Regulation of Creb1 4 0.50 2.12 2.85
87 INT156021 Positive_regulation of Transcription of Creb1 8 0.57 3.36 2.83
88 INT132575 Binding of NR1H4 57 0.20 22.06 2.82
89 INT64819 Positive_regulation of Transcription of Jun 6 0.50 4.41 2.79
90 INT321310 Positive_regulation of Nr1h4 1 0.49 1.75 2.75
91 INT98919 Negative_regulation of Phosphorylation of CREB1 8 0.58 2.4 2.63
92 INT88285 Transcription of Atf2 4 0.36 1.56 2.62
93 INT194495 Regulation of Transcription of Jun 4 0.26 2.85 2.6
94 INT52326 Negative_regulation of Atf2 7 0.45 0.94 2.5
95 INT169073 Positive_regulation of Nr1h4 8 0.47 2.44 2.45
96 INT158666 Regulation of Transcription of Creb1 6 0.45 2.41 2.44
97 INT123682 Localization of JUN 8 0.50 4.15 2.38
98 INT60199 Positive_regulation of Binding of JUN 5 0.49 1.3 2.34
99 INT87168 Positive_regulation of Binding of Creb1 4 0.48 4.6 2.21
100 INT169072 Gene_expression of Nr1h4 7 0.60 6.23 2.18
101 INT159118 Protein_catabolism of Creb1 3 0.61 0.37 2.17
102 INT106718 Regulation of Positive_regulation of Creb1 9 0.45 3.7 2.16
103 INT53981 Regulation of Binding of Jun 5 0.44 0.63 2.12
104 INT59358 Regulation of Gene_expression of Jun 10 0.61 3.7 2.11
105 INT53434 Positive_regulation of T 7 0.07 3.67 2.09
106 INT114953 Gene_expression of NR1H4 23 0.29 16.58 2.02
107 INT110925 Positive_regulation of Positive_regulation of JUN 14 0.49 6.22 1.98
108 INT130208 Positive_regulation of Phosphorylation of JUN 4 0.38 3.07 1.92
109 INT53982 Regulation of Positive_regulation of Jun 4 0.54 0.9 1.89
110 INT280889 Gene_expression of Sox10 19 0.72 3.45 1.78
111 INT69917 Negative_regulation of CREB1 8 0.58 2.28 1.59
112 INT110444 Positive_regulation of Atf2 7 0.50 2 1.48
113 INT171029 Positive_regulation of Transcription of JUN 4 0.14 2.87 1.48
114 INT207521 Gene_expression of Tfap2a 7 0.48 1.89 1.45
115 INT135132 Positive_regulation of NR1H4 17 0.30 8.63 1.38
116 INT96063 Positive_regulation of Phosphorylation of Jun 7 0.67 4.06 1.38
117 INT68652 Regulation of Positive_regulation of JUN 4 0.54 4.95 1.26
118 INT98923 Negative_regulation of Localization of Creb1 3 0.50 0.66 1.26
119 INT130207 Phosphorylation of ATF2 5 0.60 1.34 1.25
120 INT120764 Negative_regulation of Binding of JUN 7 0.25 2.65 1.23
121 INT114961 Positive_regulation of Gene_expression of NR1H4 6 0.16 3.55 1.23
122 INT141054 Binding of NFATC1 14 0.40 3.65 1.22
123 INT169721 Negative_regulation of Negative_regulation of Creb1 1 0.43 0.09 1.22
124 INT121867 Positive_regulation of Localization of Creb1 2 0.60 0.43 1.2
125 INT226407 Negative_regulation of T 2 0.21 1.81 1.18
126 INT64818 Regulation of Binding of Jun 3 0.33 1.06 1.17
127 INT203436 Negative_regulation of Gene_expression of Pou4f1 4 0.57 2.88 1.14
128 INT75503 Regulation of Gene_expression of JUN 6 0.21 2.87 1.11
129 INT298235 Binding of Pou4f1 1 0.47 2.95 1.11
130 INT142831 Positive_regulation of Gene_expression of CREB1 3 0.69 0.08 1.1
131 INT207201 Positive_regulation of Transcription of Creb1 4 0.50 0.69 1.09
132 INT208427 Regulation of T 3 0.25 3.28 1.08
133 INT203498 Localization of Pou4f1 5 0.73 3.29 1.07
134 INT321329 Positive_regulation of Positive_regulation of Nr1h4 1 0.35 0.43 1.07
135 INT71476 Negative_regulation of Regulation of Creb1 1 0.18 0.17 1.06
136 INT84511 Positive_regulation of Tfap2a 3 0.27 0.72 1.04
137 INT142829 Transcription of CREB1 9 0.46 3.37 1.03
138 INT130209 Positive_regulation of Phosphorylation of ATF2 3 0.36 1.15 1.03
139 INT133842 Binding of SOX10 3 0.38 5.79 1.02
140 INT83983 Phosphorylation of Atf2 6 0.63 2 0.95
141 INT243240 Transcription of Pou4f1 2 0.68 1.91 0.94
142 INT243974 Binding of Tfap2a 7 0.18 1.36 0.93
143 INT243533 Positive_regulation of SOX10 1 0.35 3.93 0.92
144 INT141058 Gene_expression of NFATC1 8 0.56 8.21 0.89
145 INT83984 Positive_regulation of Positive_regulation of Atf2 1 0.44 0.48 0.89
146 INT287093 Positive_regulation of Gene_expression of T 1 0.28 1.47 0.86
147 INT287090 Regulation of Gene_expression of T 1 0.18 2.77 0.86
148 INT69913 Binding of ATF2 6 0.13 0.83 0.84
149 INT203489 Positive_regulation of Gene_expression of Pou4f1 3 0.49 2.33 0.84
150 INT53978 Regulation of Regulation of Jun 4 0.38 0.18 0.83
151 INT221796 Positive_regulation of Gene_expression of Tfap2a 2 0.10 1.19 0.83
152 INT115494 Negative_regulation of Positive_regulation of CREB1 2 0.05 1.25 0.83
153 INT133841 Gene_expression of SOX10 18 0.67 9.96 0.8
154 INT287094 Transcription of T 1 0.29 1.41 0.8
155 INT80122 Gene_expression of ESRRB 4 0.41 2.21 0.78
156 INT106523 Positive_regulation of Phosphorylation of Jun 7 0.45 3.1 0.74
157 INT141057 Positive_regulation of NFATC1 5 0.57 1.95 0.74
158 INT69922 Positive_regulation of ATF2 3 0.05 1.28 0.74
159 INT207535 Transcription of Tfap2a 3 0.31 0.98 0.74
160 INT124739 Negative_regulation of Binding of Jun 2 0.40 1.45 0.74
161 INT54546 Binding of CREB1 9 0.41 3.44 0.72
162 INT114536 Regulation of Negative_regulation of Creb1 1 0.45 0 0.72
163 INT242889 Binding of SPI1 15 0.36 7.37 0.69
164 INT135197 Gene_expression of Tfap2a 1 0.45 0.48 0.69
165 INT226411 Binding of T 2 0.15 1.56 0.68
166 INT262091 Negative_regulation of Nr1h4 1 0.15 0.76 0.68
167 INT187071 Localization of ESRRB 2 0.04 0.9 0.67
168 INT154019 Protein_catabolism of Jun 2 0.61 0.07 0.67
169 INT271162 Positive_regulation of Regulation of Creb1 1 0.20 0.3 0.67
170 INT121868 Regulation of Localization of Creb1 1 0.23 0 0.66
171 INT303710 Negative_regulation of Transcription of JUN 1 0.06 0.84 0.65
172 INT242903 Gene_expression of SPI1 5 0.13 9.68 0.63
173 INT187077 Positive_regulation of Localization of ESRRB 1 0.03 0.74 0.63
174 INT93674 Regulation of Binding of Creb1 1 0.38 0.1 0.62
175 INT307186 Negative_regulation of Phosphorylation of Jun 4 0.10 2.91 0.61
176 INT142827 Regulation of Gene_expression of CREB1 3 0.61 0.39 0.61
177 INT127262 Negative_regulation of Transcription of Jun 1 0.30 0.52 0.61
178 INT207529 Localization of Tfap2a 2 0.34 0.13 0.6
179 INT103888 Gene_expression of Atf2 7 0.58 1.69 0.59
180 INT123681 Positive_regulation of Localization of JUN 2 0.25 1.3 0.59
181 INT303595 Negative_regulation of Localization of Creb1 1 0.19 0.86 0.57
182 INT113840 Negative_regulation of Gene_expression of JUN 10 0.58 5.23 0.56
183 INT243970 Phosphorylation of Tfap2a 2 0.25 0.56 0.56
184 INT88290 Positive_regulation of Transcription of Atf2 1 0.31 0.09 0.56
185 INT88291 Regulation of Transcription of Atf2 1 0.18 0.1 0.55
186 INT17594 Positive_regulation of Regulation of Jun 1 0.43 0 0.55
187 INT125207 Positive_regulation of Negative_regulation of Pou4f1 1 0.21 0.69 0.5
188 INT141052 Transcription of NFATC1 5 0.44 1.34 0.49
189 INT243538 Regulation of SOX10 1 0.31 3.27 0.48
190 INT74209 Positive_regulation of Negative_regulation of JUN 1 0.45 0.26 0.47
191 INT230623 Negative_regulation of SOX10 2 0.36 0.46 0.46
192 INT207194 Regulation of Regulation of Creb1 2 0.45 1.09 0.46
193 INT317620 Negative_regulation of Binding of Creb1 1 0.40 0.81 0.46
194 INT116134 Positive_regulation of Positive_regulation of CREB1 2 0.28 0.59 0.45
195 INT142828 Regulation of Transcription of CREB1 1 0.24 0 0.45
196 INT93214 Positive_regulation of Phosphorylation of Atf2 2 0.38 0.99 0.44
197 INT262102 Binding of Nr1h4 1 0.13 0.34 0.43
198 INT147482 Regulation of Phosphorylation of Atf2 1 0.22 0.56 0.43
199 INT70561 Regulation of ESRRB 4 0.27 1.03 0.42
200 INT69915 Regulation of ATF2 2 0.34 0.81 0.42
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