GO:0001078

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Latest revision as of 10:09, 28 January 2013

Name RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
Categary Function
Go Slim No
Go Link GO:0001078
Unique Molecular Interactions 267
Total Molecular Interactions 459
Total Single Events 1218
Pain Genes Associated 27

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

[edit] Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription. They are ordered first by their pain relevance and then by number of times they were reported for RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT200322 Binding of Rest and Sp3 1 0.39 2.93 3.98
2 INT200335 Binding of Oprm1 and Rest 1 0.40 0.07 1.7
3 INT114929 Positive_regulation of Binding of Oprm1 and Crebbp 1 0.06 0.14 1.28
4 INT114925 Binding of Oprm1 and Crebbp 1 0.06 0.14 1.27
5 INT167278 Binding of OPRM1 and REST 1 0.08 0.94 1.24
6 INT281373 Tcf21 Regulation of Fig4 1 0.03 0.67 1.2
7 INT281379 Tcf21 Regulation of FSCN1 1 0.01 0.66 1.19
8 INT200312 Rest Regulation of Oprm1 1 0.23 0.27 1.16
9 INT133072 GATA3 Positive_regulation of Transcription of OPRM1 1 0.35 0 1.04
10 INT200307 Rest Negative_regulation of Rorb 1 0.00 0.1 1.03
11 INT316128 TCF21 Negative_regulation of Gene_expression of HLA-DRA 1 0.07 0.13 0.99
12 INT200323 Binding of Oprm1 and Sp3 1 0.39 0 0.99
13 INT133071 STAT6 Positive_regulation of Gene_expression of GATA3 1 0.55 0 0.95
14 INT200308 Binding of Rest and Rorb 1 0.00 0 0.87
15 INT63594 Snai1 Negative_regulation of Binding of Ugt1a2 1 0.05 0.32 0.82
16 INT63596 Snai1 Negative_regulation of ITS 1 0.00 0.31 0.81
17 INT266102 Binding of PITX2 and RS1 1 0.00 0.64 0.8
18 INT98951 Positive_regulation of Binding of NR5A2 and SP3 1 0.00 0 0.7
19 INT98957 Binding of NR5A2 and SP3 1 0.00 0 0.7
20 INT207540 Tfap2a Regulation of Oprm1 1 0.13 0.06 0.7
21 INT135207 Gmeb1 Regulation of Gene_expression of Tfap2a 1 0.07 0.48 0.69
22 INT135206 Ighen Regulation of Gene_expression of Tfap2a 1 0.06 0.48 0.69
23 INT135202 Tfap2a Regulation of Gene_expression of Ighen 1 0.06 0.48 0.69
24 INT135213 Tfap2a Regulation of Gene_expression of Nfkb1 1 0.02 0.48 0.69
25 INT135211 Nfkb1 Regulation of Gene_expression of Tfap2a 1 0.02 0.48 0.69
26 INT135204 Tfap2a Regulation of Gene_expression of Gmeb1 1 0.10 0.48 0.69
27 INT207543 Tfap2a Regulation of Qsox1 1 0.04 0.06 0.67
28 INT200317 Rest Negative_regulation of Transcription of Oprm1 1 0.31 0 0.64
29 INT98955 Positive_regulation of Binding of SP3 and CFHR4 1 0.00 0 0.62
30 INT98952 Binding of SP3 and CFHR4 1 0.00 0 0.61
31 INT200348 Sp3 Negative_regulation of Gene_expression of Oprm1 1 0.48 0.4 0.55
32 INT222246 Binding of Ccr2 and Tcf21 1 0.29 0.67 0.55
33 INT222249 Positive_regulation of Binding of Ccr2 and Tcf21 1 0.39 0.67 0.55
34 INT281124 Tcf21 Positive_regulation of Binding of Ddc 1 0.04 1.21 0.54
35 INT281129 Tcf21 Positive_regulation of Binding of Cd4 1 0.04 1.21 0.54
36 INT281152 Tcf21 Positive_regulation of Binding of ITIH4 1 0.03 1.21 0.54
37 INT281131 Tcf21 Positive_regulation of Rent1 1 0.00 1.19 0.53
38 INT281374 Tcf21 Positive_regulation of Gene_expression of Sds 1 0.03 0 0.51
39 INT244028 Positive_regulation of Binding of Cacnb3 and Tfap2a 1 0.01 0.24 0.49
40 INT244037 Positive_regulation of Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
41 INT200321 Binding of Rest and Negative_regulation of Gene_expression of Oprm1 1 0.36 0.05 0.49
42 INT244000 Positive_regulation of Binding of Tfap2a and Dnm1 1 0.04 0.24 0.49
43 INT244035 Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
44 INT243997 Binding of Tfap2a and Dnm1 1 0.03 0.24 0.49
45 INT244060 Binding of Cacnb3 and Tfap2a 1 0.00 0.24 0.49
46 INT319718 Binding of Crebbp and Creb1 1 0.10 1.68 0.48
47 INT200327 Oprm1 Negative_regulation of Gene_expression of Rest 1 0.31 0 0.41
48 INT200314 Oprm1 Regulation of Rest 1 0.20 0.1 0.39
49 INT200353 Rest Negative_regulation of Oprm1 1 0.31 0.1 0.39
50 INT89332 Binding of SP1 and SP3 1 0.30 0.76 0.39
51 INT200313 Sp3 Regulation of Oprm1 1 0.10 0.07 0.38
52 INT200301 Sp3 Regulation of Rorb 1 0.00 0.07 0.38
53 INT200302 Rest Regulation of Rorb 1 0.00 0.07 0.38
54 INT319729 Binding of Rela and Crebbp 1 0.02 0.88 0.37
55 INT167551 Binding of MECP2 and SP3 1 0.01 0.06 0.35
56 INT200333 Binding of Rest and Sp1 1 0.24 0.07 0.35
57 INT200316 Sp1 Regulation of Gene_expression of Rest 1 0.31 0 0.35
58 INT200352 Binding of Rest and Rcor2 1 0.16 0.44 0.34
59 INT301054 Tfap2a Regulation of Gene_expression of Faslg 1 0.00 1.23 0.34
60 INT182837 Binding of Creb1 and Crebbp 1 0.12 0.57 0.32
61 INT222251 Negative_regulation of Binding of Cxcl10 and Tcf21 1 0.23 0.34 0.32
62 INT253576 Binding of Lpl and Sp3 1 0.22 0.85 0.32
63 INT222247 Binding of Cxcl10 and Tcf21 1 0.20 0.34 0.32
64 INT300752 GATA3 Regulation of Hand2 1 0.01 0.06 0.3
65 INT200351 Sp1 Positive_regulation of Gene_expression of Rest 1 0.34 0.07 0.3
66 INT281127 Tcf21 Positive_regulation of Gene_expression of Cxcr4 1 0.08 0.42 0.3
67 INT96788 Binding of SP3 and NR2F2 1 0.24 0.27 0.27
68 INT96790 SP3 Positive_regulation of GDF15 1 0.20 0.26 0.27
69 INT317773 Positive_regulation of GATA3 Positive_regulation of HDAC1 1 0.23 0.69 0.25
70 INT317775 GATA3 Positive_regulation of HDAC1 1 0.23 0.69 0.25
71 INT118418 Gata1 Positive_regulation of Transcription of Tac2 1 0.61 0.77 0.25
72 INT118419 Binding of Gata1 and Tac2 1 0.31 0.7 0.24
73 INT200309 Positive_regulation of Binding of Rest and Sp3 1 0.41 0.88 0.24
74 INT97691 Binding of REST and HDAC9 1 0.26 0.09 0.23
75 INT253568 Negative_regulation of Binding of Lpl and Sp3 1 0.19 0.37 0.22
76 INT97694 Ngf Negative_regulation of Gene_expression of REST 1 0.01 0.09 0.21
77 INT297545 Pou3f3 Regulation of Hes1 1 0.05 0.41 0.2
78 INT203532 Negative_regulation of Pou4f1 Negative_regulation of Gene_expression of Pou4f2 1 0.34 0.44 0.19
79 INT149096 PITX2 Positive_regulation of Gene_expression of Egr1 1 0.01 1.23 0.19
80 INT119265 Binding of CREBBP and PPM1E 1 0.01 0.46 0.17
81 INT194811 Binding of Crebbp and Nfatc1 1 0.00 0.07 0.16
82 INT341818 Binding of PITX2 and Aia1 1 0.00 0.53 0.16
83 INT194826 Binding of CREB1 and Crebbp 1 0.02 0.07 0.16
84 INT104797 Smarce1 Positive_regulation of REST 1 0.01 0.24 0.15
85 INT194829 Gata3 Positive_regulation of IL13 1 0.01 0.12 0.15
86 INT149095 PITX2 Positive_regulation of Casp3 1 0.00 1.51 0.15
87 INT149092 PITX2 Positive_regulation of RFFL 1 0.00 1.51 0.15
88 INT194835 Gata3 Positive_regulation of IL5 1 0.01 0.12 0.15
89 INT316479 Il6 Positive_regulation of Snai1 1 0.24 0.33 0.15
90 INT194833 Binding of IL5 and Gata3 1 0.01 0.12 0.15
91 INT194827 Binding of IL13 and Gata3 1 0.01 0.12 0.15
92 INT200328 Sp3 Positive_regulation of Gene_expression of Oprm1 1 0.38 0 0.13
93 INT338428 Il4 Positive_regulation of Gata3 1 0.06 0.75 0.13
94 INT200338 Rest Positive_regulation of Gene_expression of Oprm1 1 0.36 0 0.13
95 INT287878 Binding of CREB1 and CREBBP 2 0.01 0.16 0.12
96 INT200315 Binding of Sp1 and Sp3 1 0.29 0 0.12
97 INT319726 Crebbp Positive_regulation of Binding of Rela 1 0.02 0.37 0.12
98 INT319727 Binding of Crebbp and Ep300 1 0.02 0.36 0.11
99 INT319728 Positive_regulation of Binding of Crebbp and Ep300 1 0.03 0.36 0.11
100 INT200320 Binding of Sp3 and Negative_regulation of Gene_expression of Oprm1 1 0.35 0.4 0.1
101 INT153637 Gene_expression of REST Positive_regulation of Gene_expression of Oprm1 1 0.03 0.08 0.1
102 INT210992 Binding of KCNMA1 and SP3 1 0.00 0.17 0.1
103 INT210989 Binding of FSCN1 and SP3 1 0.00 0.17 0.1
104 INT297548 Neurod1 Regulation of Hes1 1 0.05 0.2 0.1
105 INT210988 Binding of SP3 and PKDREJ 1 0.01 0.17 0.1
106 INT210994 Binding of SEA and SP3 1 0.00 0.17 0.1
107 INT153636 Binding of REST and Oprm1 1 0.02 0.09 0.09
108 INT191758 ROS1 Positive_regulation of TFAP2A 1 0.01 0.54 0.08
109 INT196213 REST Regulation of Gene_expression of CACNA1A 1 0.46 0.08 0.08
110 INT343792 Binding of TCF21 and CORO7 1 0.01 0.51 0.07
111 INT1226 Fabp6 Negative_regulation of Snai1 1 0.03 0.49 0.07
112 INT119268 CDKN1A Regulation of CREBBP 1 0.21 0.44 0.07
113 INT253570 Binding of Csnk2a2 and Sp3 1 0.16 0.2 0.07
114 INT22568 Cyp1a1 Positive_regulation of Tcf21 1 0.04 0 0.06
115 INT118417 Gata1 Regulation of Gene_expression of Serpinb9g 1 0.17 0.12 0.06
116 INT22567 Cyp1a2 Positive_regulation of Tcf21 1 0.04 0 0.06
117 INT235640 Binding of GATA3 and Mrgpre 1 0.01 0.8 0.04
118 INT269214 SNAI1 Positive_regulation of Positive_regulation of CDH1 1 0.35 0.71 0.04
119 INT269211 SNAI1 Positive_regulation of Gene_expression of CDH1 1 0.40 0.73 0.04
120 INT233849 Twist1 Positive_regulation of Snai2 1 0.07 0.58 0.04
121 INT233848 Zeb1 Positive_regulation of Snai1 1 0.07 0.58 0.04
122 INT233853 Zeb1 Positive_regulation of Snai2 1 0.09 0.58 0.04
123 INT170328 Gene_expression of Ido1 Positive_regulation of Hmga2 1 0.01 0.13 0.04
124 INT233852 Twist1 Positive_regulation of Snai1 1 0.02 0.58 0.04
125 INT253574 Sp3 Positive_regulation of Lpl 1 0.22 0 0.03
126 INT200311 Htt Positive_regulation of Rest 1 0.05 0.75 0.03
127 INT280849 REST Negative_regulation of Gene_expression of Avp 1 0.09 0.09 0
128 INT339047 Binding of PITX2 and SNRNP70 1 0.00 0.52 0
129 INT196948 Hmga2 Positive_regulation of Hdac1 1 0.36 0.23 0
130 INT196208 REST Regulation of CACNA1A 1 0.46 0.06 0
131 INT196216 Binding of CACNA1A and REST 1 0.28 0 0
132 INT264735 Binding of Hes1 and Mir199b 1 0.08 0.93 0
133 INT121179 Binding of Htt and Rest 1 0.07 0.45 0
134 INT243106 Binding of Crebbp and Src 1 0.05 0.52 0
135 INT264738 Mir199b Regulation of Gene_expression of Hes1 1 0.08 0.89 0
136 INT298451 Binding of SNAI1 and Vim 1 0.07 1.45 0
137 INT298437 Binding of ITK and SNAI1 1 0.05 1.16 0
138 INT180028 Gopc Regulation of Bhlhe41 1 0.12 1.17 0
139 INT339043 SNRNP70 Regulation of PITX2 1 0.00 1.42 0
140 INT287882 Binding of CREBBP and HNF4A 1 0.01 0.85 0
141 INT245820 Binding of Sp1 and Tfap2a 1 0.03 0.64 0
142 INT264736 Hes1 Regulation of Notch2 1 0.20 0.13 0
143 INT196959 Hmga2 Positive_regulation of Localization of E2f1 1 0.54 0.24 0
144 INT269209 SNAI1 Regulation of Gene_expression of LOXL2 1 0.07 1.14 0
145 INT336780 Ighmbp2 Regulation of ERAP2 1 0.02 0.15 0
146 INT197316 Hes1 Regulation of Atoh1 1 0.01 0.14 0
147 INT250557 Binding of PITX2 and CHDH 1 0.00 2.83 0
148 INT172606 EP300 Positive_regulation of CREBBP 1 0.00 0.07 0
149 INT196940 Positive_regulation of Hmga2 Positive_regulation of E2f1 1 0.50 0.47 0
150 INT235165 Atxn3 Regulation of Transcription of Crebbp 1 0.02 0.3 0
151 INT197304 Ahr Regulation of Hes1 1 0.06 0.17 0
152 INT296999 Binding of EPS15 and TFAP2A 1 0.06 0.2 0
153 INT339044 Binding of PITX2 and SUGT1 1 0.00 2.25 0
154 INT264731 Gene_expression of Hes1 Negative_regulation of Positive_regulation of Musd1 1 0.00 0.18 0
155 INT269213 Binding of SNAI1 and Positive_regulation of Gene_expression of CDH1 1 0.37 1.03 0
156 INT196961 Binding of Hmga2 and Rb1 1 0.48 6.47 0
157 INT354309 Binding of MYC and PITX2 1 0.01 0.51 0
158 INT245828 Binding of VEGFA and Tfap2a 1 0.01 0.64 0
159 INT243233 Positive_regulation of Ighmbp2 Negative_regulation of Rs1 1 0.11 0.31 0
160 INT298436 Binding of KNG1 and SNAI1 1 0.09 0.53 0
161 INT197315 Hes5 Regulation of Atoh1 1 0.00 0.14 0
162 INT217151 Gene_expression of MIR98 Negative_regulation of HMGA2 1 0.24 1.08 0
163 INT304168 Binding of Gata1 and Sfpi1 1 0.08 0.07 0
164 INT314857 Atoh7 Regulation of Pou4f2 1 0.21 0.21 0
165 INT243235 Ighmbp2 Negative_regulation of Rs1 1 0.11 0.31 0
166 INT339049 Binding of PITX2 and RENBP 1 0.00 0.27 0
167 INT280848 Binding of REST and Rest 1 0.02 0.09 0
168 INT332963 Atp6v1e1 Negative_regulation of Binding of Crebbp 1 0.08 0 0
169 INT268600 Mirlet7a-1 Regulation of HMGA2 1 0.01 0.72 0
170 INT196956 Binding of Hmga2 and Hdac1 1 0.25 0.23 0
171 INT196947 Binding of Rb1 and Positive_regulation of Hmga2 1 0.50 0.3 0
172 INT196951 Hmga2 Positive_regulation of E2f1 1 0.50 0.98 0
173 INT197314 Hes5 Regulation of Ascl1 1 0.00 0.14 0
174 INT264729 Mir199b Regulation of Hes1 1 0.05 0.25 0
175 INT196215 Binding of L1RE1 and REST 1 0.33 0.47 0
176 INT196942 Binding of E2f1 and Hmga2 1 0.39 0.87 0
177 INT243111 Binding of Crebbp and Ep300 1 0.16 0.17 0
178 INT253567 Binding of Pik3r1 and Sp3 1 0.11 0.06 0
179 INT292139 SP3 Positive_regulation of Transcription of HIVEP1 1 0.02 0.42 0
180 INT197310 Hes1 Regulation of Ascl1 1 0.01 0.14 0
181 INT217142 MIR98 Regulation of Gene_expression of HMGA2 1 0.40 2.22 0
182 INT196209 Binding of REST and SNAP25 1 0.25 0 0
183 INT121178 Binding of Bdnf and Rest 1 0.10 0.91 0
184 INT264725 Binding of Hes1 and Notch1 1 0.03 0.84 0
185 INT264734 Mir199b Negative_regulation of Negative_regulation of Hes1 1 0.07 0.1 0
186 INT243232 Ighmbp2 Negative_regulation of Ptch1 1 0.02 0.22 0
187 INT196953 Hmga2 Negative_regulation of Rb1 1 0.59 0.35 0
188 INT280837 Binding of Rest and Negative_regulation of Gene_expression of Avp 1 0.00 0.09 0
189 INT298438 Binding of CDH1 and SNAI1 1 0.14 1.16 0
190 INT264739 Mir199b Negative_regulation of Gene_expression of Hes1 1 0.07 0.82 0
191 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0
192 INT196214 Binding of FRAXD and REST 1 0.00 0.07 0
193 INT264733 Hes1 Regulation of Mir199b 1 0.05 0.43 0

[edit] Single Events

The table below shows the top 100 pain related interactions that have been reported for RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription. They are ordered first by their pain relevance and then by number of times they were reported in RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT215353 Gene_expression of Tcf21 16 0.59 9.71 9.49
2 INT1223 Negative_regulation of Snai1 15 0.38 2.05 8.46
3 INT20914 Positive_regulation of Snai1 13 0.41 3.41 7.69
4 INT97693 Gene_expression of REST 29 0.75 5.51 5.26
5 INT72834 Negative_regulation of Tcf21 10 0.58 5.8 4.84
6 INT198736 Binding of Sp3 23 0.40 4.77 4.42
7 INT116011 Positive_regulation of Gata3 5 0.31 3.17 4.21
8 INT202417 Gene_expression of Gata3 16 0.61 7.84 4.12
9 INT22566 Positive_regulation of Tcf21 8 0.65 3.06 3.75
10 INT200248 Gene_expression of Rest 1 0.66 1.25 3.7
11 INT34977 Gene_expression of Hmga2 11 0.76 12.39 3.07
12 INT199255 Binding of Rest 14 0.41 1.43 2.94
13 INT133080 Gene_expression of GATA3 15 0.61 5.64 2.89
14 INT108793 Gene_expression of PITX2 12 0.75 3.91 2.89
15 INT281367 Regulation of Gene_expression of Tcf21 1 0.09 1.39 2.89
16 INT1225 Regulation of Snai1 10 0.30 1.05 2.72
17 INT89336 Binding of SP3 6 0.47 1.75 2.63
18 INT202419 Positive_regulation of Gene_expression of Gata3 6 0.52 5.47 2.6
19 INT281369 Negative_regulation of Gene_expression of Tcf21 1 0.08 1.4 2.44
20 INT269217 Gene_expression of SNAI1 81 0.76 80.49 2.26
21 INT90004 Gene_expression of TCF21 4 0.65 2.48 2.02
22 INT316162 Localization of TCF21 1 0.18 0.28 1.71
23 INT32024 Positive_regulation of Positive_regulation of Snai1 2 0.25 0.32 1.7
24 INT55302 Binding of Snai1 2 0.31 1.94 1.63
25 INT153635 Positive_regulation of Gene_expression of REST 10 0.54 1.38 1.6
26 INT118412 Gene_expression of Gata1 5 0.62 0.83 1.6
27 INT118413 Positive_regulation of Gene_expression of Gata1 3 0.40 0.68 1.56
28 INT28367 Positive_regulation of REST 10 0.54 2.07 1.52
29 INT136459 Gene_expression of Sp3 6 0.64 1.97 1.47
30 INT116014 Transcription of Gata3 4 0.63 2.24 1.46
31 INT207521 Gene_expression of Tfap2a 7 0.48 1.89 1.45
32 INT116015 Regulation of Gata3 3 0.22 1.41 1.42
33 INT116008 Binding of Gata3 2 0.34 1.37 1.41
34 INT165005 Binding of REST 26 0.43 2.81 1.39
35 INT222228 Positive_regulation of Gene_expression of Tcf21 4 0.38 0.84 1.39
36 INT110485 Binding of Tcf21 2 0.36 0.76 1.37
37 INT319724 Binding of Crebbp 1 0.16 4.19 1.34
38 INT116016 Positive_regulation of Positive_regulation of Gata3 2 0.21 0.5 1.28
39 INT316154 Positive_regulation of TCF21 4 0.17 1.22 1.23
40 INT100154 Regulation of PITX2 5 0.60 0.48 1.15
41 INT133079 Positive_regulation of Gene_expression of GATA3 3 0.50 1.03 1.11
42 INT332771 Phosphorylation of Tcf21 1 0.09 0.21 1.07
43 INT332772 Positive_regulation of Phosphorylation of Tcf21 1 0.06 0.21 1.07
44 INT84511 Positive_regulation of Tfap2a 3 0.27 0.72 1.04
45 INT97032 Gene_expression of Snai1 3 0.52 0.58 1.04
46 INT108795 Transcription of PITX2 1 0.69 0.46 0.96
47 INT34978 Negative_regulation of Gene_expression of Hmga2 2 0.42 1.53 0.95
48 INT117880 Negative_regulation of Crebbp 3 0.38 0.69 0.94
49 INT114922 Phosphorylation of Crebbp 2 0.21 0.92 0.94
50 INT243974 Binding of Tfap2a 7 0.18 1.36 0.93
51 INT136458 Negative_regulation of Sp3 3 0.39 1.53 0.93
52 INT190591 Positive_regulation of Rest 3 0.37 2.52 0.92
53 INT102677 Negative_regulation of TCF21 2 0.41 0.22 0.89
54 INT138980 Binding of PITX2 15 0.47 10.34 0.88
55 INT200255 Localization of Rest 1 0.68 0.14 0.86
56 INT221796 Positive_regulation of Gene_expression of Tfap2a 2 0.10 1.19 0.83
57 INT149817 Gene_expression of Bhlhe41 2 0.43 2.47 0.81
58 INT114956 Gene_expression of CREBBP 5 0.31 1.56 0.75
59 INT207535 Transcription of Tfap2a 3 0.31 0.98 0.74
60 INT116012 Regulation of Positive_regulation of Gata3 1 0.20 0.07 0.71
61 INT144995 Positive_regulation of Gata1 1 0.37 0.14 0.71
62 INT116006 Positive_regulation of Transcription of Gata3 1 0.21 0.07 0.7
63 INT116010 Positive_regulation of Binding of Gata3 1 0.31 0.07 0.7
64 INT149819 Regulation of Gene_expression of Bhlhe41 1 0.29 0 0.7
65 INT135197 Gene_expression of Tfap2a 1 0.45 0.48 0.69
66 INT149804 Regulation of Bhlhe41 1 0.29 0 0.69
67 INT248470 Gene_expression of Ighmbp2 5 0.75 3.32 0.68
68 INT88987 Gene_expression of HMGA2 8 0.77 10.46 0.64
69 INT202416 Negative_regulation of Gata3 2 0.32 1.17 0.64
70 INT264709 Gene_expression of Hes1 24 0.76 7.04 0.63
71 INT17840 Negative_regulation of GATA3 3 0.41 1.96 0.63
72 INT205470 Positive_regulation of GATA3 4 0.33 2.53 0.61
73 INT114955 Positive_regulation of Gene_expression of CREBBP 2 0.23 0.24 0.61
74 INT207529 Localization of Tfap2a 2 0.34 0.13 0.6
75 INT290660 Negative_regulation of Gene_expression of Gata3 1 0.25 1.52 0.6
76 INT80300 Gene_expression of TFAP2A 5 0.54 2.76 0.59
77 INT281366 Regulation of Tcf21 1 0.09 0.23 0.59
78 INT54000 Positive_regulation of SNAI1 7 0.49 5.37 0.58
79 INT226481 Negative_regulation of Gene_expression of GATA3 1 0.06 1.41 0.57
80 INT243970 Phosphorylation of Tfap2a 2 0.25 0.56 0.56
81 INT316161 Negative_regulation of Gene_expression of TCF21 1 0.10 0.11 0.56
82 INT200273 Negative_regulation of Rest 1 0.43 0.69 0.55
83 INT153634 Regulation of REST 4 0.48 1.42 0.54
84 INT182835 Phosphorylation of Crebbp 2 0.26 0.78 0.54
85 INT144053 Transcription of GATA3 1 0.67 0.89 0.54
86 INT117879 Regulation of Crebbp 1 0.24 0 0.54
87 INT182836 Positive_regulation of Crebbp 2 0.21 0.76 0.53
88 INT88170 Positive_regulation of HMGA2 2 0.69 2 0.48
89 INT200264 Localization of Sp3 1 0.62 0 0.47
90 INT299799 Negative_regulation of Negative_regulation of GATA3 1 0.09 1.32 0.47
91 INT253558 Negative_regulation of Binding of Sp3 1 0.39 1.09 0.46
92 INT222229 Localization of Tcf21 1 0.57 0.45 0.45
93 INT203478 Gene_expression of Crebbp 3 0.46 2.15 0.44
94 INT98969 Regulation of Binding of SP3 1 0.26 0 0.41
95 INT319725 Positive_regulation of Binding of Crebbp 1 0.17 1.12 0.4
96 INT165006 Positive_regulation of Binding of REST 1 0.23 0.94 0.4
97 INT89333 Negative_regulation of SP3 1 0.38 0.77 0.39
98 INT89335 Negative_regulation of Binding of SP3 1 0.38 0.77 0.39
99 INT80302 Binding of TFAP2A 7 0.39 1.67 0.38
100 INT98960 Positive_regulation of Binding of SP3 1 0.67 0 0.37
101 INT123578 Negative_regulation of Gene_expression of Snai1 1 0.33 0.5 0.36
102 INT123579 Negative_regulation of Positive_regulation of Snai1 1 0.33 0.51 0.36
103 INT106402 Positive_regulation of TFAP2A 2 0.13 0.35 0.35
104 INT88167 Negative_regulation of Positive_regulation of HMGA2 1 0.41 0.16 0.35
105 INT200269 Negative_regulation of Transcription of Rest 1 0.31 0.08 0.35
106 INT200245 Transcription of Rest 1 0.51 0.08 0.35
107 INT200265 Regulation of Sp3 2 0.37 0.25 0.34
108 INT173635 Negative_regulation of TFAP2A 3 0.34 2.93 0.33
109 INT135495 Regulation of Positive_regulation of Snai1 1 0.23 0 0.33
110 INT200270 Regulation of Rest 1 0.20 0.07 0.32
111 INT200256 Negative_regulation of Regulation of Rest 1 0.32 0.07 0.32
112 INT88988 Positive_regulation of Gene_expression of HMGA2 1 0.69 4.05 0.29
113 INT269225 Negative_regulation of Gene_expression of SNAI1 4 0.58 9.11 0.28
114 INT196937 Positive_regulation of Hmga2 3 0.68 2.47 0.28
115 INT200276 Positive_regulation of Sp3 1 0.42 0.17 0.28
116 INT292207 Negative_regulation of Gene_expression of TFAP2A 1 0.05 1.2 0.27
117 INT166727 Regulation of Gene_expression of PITX2 1 0.60 0.09 0.26
118 INT319719 Negative_regulation of Binding of Crebbp 1 0.14 0.51 0.26
119 INT200251 Phosphorylation of Sp3 2 0.67 0.42 0.24
120 INT104789 Negative_regulation of REST 3 0.33 0.44 0.23
121 INT221770 Positive_regulation of Phosphorylation of Crebbp 1 0.14 0.21 0.23
122 INT58734 Regulation of SNAI1 3 0.60 1.26 0.2
123 INT136452 Negative_regulation of Negative_regulation of Sp3 1 0.28 0.65 0.2
124 INT162483 Localization of Snai1 1 0.43 0 0.19
125 INT162484 Regulation of Localization of Snai1 1 0.33 0 0.19
126 INT203497 Gene_expression of Pou4f2 1 0.63 1.05 0.19
127 INT149094 Positive_regulation of Gene_expression of PITX2 1 0.05 1.23 0.19
128 INT264701 Negative_regulation of Gene_expression of Hes1 1 0.42 0.73 0.18
129 INT269228 Binding of SNAI1 1 0.47 2.28 0.18
130 INT181783 Transcription of SNAI1 3 0.71 2.44 0.17
131 INT162939 Binding of Tfap2a 1 0.26 0.34 0.17
132 INT162940 Negative_regulation of Tfap2a 1 0.32 0.34 0.17
133 INT200275 Positive_regulation of Gene_expression of Rest 1 0.59 0.92 0.17
134 INT162941 Negative_regulation of Binding of Tfap2a 1 0.32 0.34 0.17
135 INT58735 Negative_regulation of Regulation of SNAI1 1 0.33 0.24 0.17
136 INT136454 Positive_regulation of Gene_expression of Sp3 1 0.33 0.44 0.16
137 INT152666 Negative_regulation of CREBBP 2 0.06 0.52 0.14
138 INT220570 Transcription of Gata1 2 0.05 0.91 0.14
139 INT307932 Localization of Snai1 3 0.78 2.28 0.13
140 INT200261 Positive_regulation of Transcription of Sp3 1 0.42 0 0.13
141 INT200280 Transcription of Sp3 1 0.57 0 0.13
142 INT316436 Positive_regulation of Snai1 1 0.22 0.35 0.13
143 INT194746 Phosphorylation of Gata3 1 0.10 0.08 0.12
144 INT319722 Positive_regulation of Crebbp 1 0.17 0.62 0.12
145 INT319723 Protein_catabolism of Crebbp 1 0.30 0.56 0.12
146 INT319721 Gene_expression of Crebbp 2 0.23 0.76 0.11
147 INT200281 Negative_regulation of Negative_regulation of Rest 1 0.31 0.44 0.11
148 INT243228 Protein_catabolism of Ighmbp2 3 0.16 0.83 0.1
149 INT200268 Positive_regulation of Binding of Sp3 2 0.39 0.8 0.1
150 INT253546 Positive_regulation of Phosphorylation of Sp3 1 0.29 0.42 0.09
151 INT211005 Gene_expression of SP3 1 0.03 0.58 0.09
152 INT171528 Binding of CREBBP 3 0.07 0.47 0.08
153 INT170298 Regulation of Gene_expression of Hmga2 1 0.01 0.48 0.08
154 INT196248 Localization of REST 1 0.66 0.15 0.08
155 INT269218 Localization of SNAI1 4 0.79 3.1 0.07
156 INT88990 Binding of HMGA2 1 0.48 0.95 0.07
157 INT190034 Transcription of Ighmbp2 3 0.07 0.95 0.06
158 INT298251 Gene_expression of Hes5 2 0.45 0.39 0.06
159 INT170300 Positive_regulation of Gene_expression of Hmga2 2 0.68 4.51 0.06
160 INT170302 Regulation of Hmga2 2 0.44 0.94 0.06
161 INT97754 Regulation of Gene_expression of TFAP2A 1 0.36 0.13 0.06
162 INT262962 Localization of PITX2 1 0.42 0.64 0.06
163 INT253554 Regulation of Negative_regulation of Sp3 1 0.30 0 0.05
164 INT180026 Positive_regulation of Bhlhe41 1 0.35 0.79 0.05
165 INT298445 Positive_regulation of Gene_expression of SNAI1 4 0.59 5.07 0.04
166 INT197017 Binding of GATA3 2 0.36 0.94 0.04
167 INT319060 Localization of Crebbp 2 0.73 0 0.04
168 INT269219 Phosphorylation of SNAI1 1 0.62 0.38 0.04
169 INT356474 Negative_regulation of PITX2 1 0.03 0.07 0.04
170 INT264717 Negative_regulation of Hes1 7 0.42 0.77 0.03
171 INT264704 Regulation of Hes1 4 0.44 1.03 0.03
172 INT248475 Regulation of Ighmbp2 2 0.05 0.96 0.03
173 INT203460 Negative_regulation of Gene_expression of Crebbp 2 0.25 0.73 0.03
174 INT243077 Regulation of Crebbp 1 0.27 0.13 0.03
175 INT203462 Negative_regulation of Crebbp 1 0.02 0.62 0.03
176 INT243085 Positive_regulation of Gene_expression of Crebbp 1 0.30 0.14 0.03
177 INT76371 Protein_catabolism of Hmga2 1 0.02 0.06 0.03
178 INT264702 Positive_regulation of Gene_expression of Hes1 1 0.68 1.39 0.03
179 INT187585 Binding of Crebbp 6 0.36 0.11 0
180 INT264719 Regulation of Gene_expression of Hes1 2 0.28 0.12 0
181 INT269222 Regulation of Gene_expression of SNAI1 2 0.27 2.24 0
182 INT250574 Positive_regulation of PITX2 2 0.02 1.79 0
183 INT172620 Localization of CREBBP 2 0.09 0.06 0
184 INT337420 Negative_regulation of Localization of Crebbp 1 0.41 0 0
185 INT340511 Localization of Crebbp 1 0.26 0 0
186 INT264708 Transcription of Hes1 1 0.67 0.83 0
187 INT336756 Regulation of Transcription of Ighmbp2 1 0.03 0 0
188 INT196931 Phosphorylation of Hmga2 1 0.80 0.4 0
189 INT173648 Regulation of Binding of TFAP2A 1 0.03 0.32 0
190 INT196923 Binding of Hmga2 1 0.47 2.5 0
191 INT292209 Regulation of SP3 1 0.17 0.34 0
192 INT337421 Negative_regulation of Binding of Crebbp 1 0.41 0 0
193 INT276802 Negative_regulation of Gene_expression of CREBBP 1 0.03 0 0
194 INT300344 Localization of HMGA2 1 0.42 1.75 0
195 INT136451 Protein_catabolism of Sp3 1 0.66 0.15 0
196 INT217195 Negative_regulation of HMGA2 1 0.55 3.54 0
197 INT173631 Negative_regulation of Positive_regulation of TFAP2A 1 0.05 0.27 0
198 INT136461 Positive_regulation of Protein_catabolism of Sp3 1 0.46 0.15 0
199 INT248485 Positive_regulation of Gene_expression of Ighmbp2 1 0.05 0.1 0
200 INT340512 Positive_regulation of Gene_expression of Crebbp 1 0.17 0 0
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