GO:0001890

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Name placenta development
Categary Process
Go Slim No
Go Link GO:0001890
Unique Molecular Interactions 558
Total Molecular Interactions 758
Total Single Events 6758
Pain Genes Associated 42

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for placenta development. They are ordered first by their pain relevance and then by number of times they were reported for placenta development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78
2 INT278948 LEP Positive_regulation of Gene_expression of PTGER2 1 0.09 4.04 2.69
3 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
4 INT83170 Lep Regulation of Cck 5 0.43 0.68 1.96
5 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
6 INT326509 Binding of ACE and VWF 1 0.05 2.07 1.59
7 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
8 INT158762 Binding of Vwf and Mthfr 1 0.05 1.85 1.37
9 INT42579 SOD1 Negative_regulation of POMC 1 0.16 0.43 1.27
10 INT84886 APC Regulation of PPARD 1 0.51 1.57 1.26
11 INT117311 HP Positive_regulation of Lep 1 0.00 1.78 1.01
12 INT278962 LEP Positive_regulation of CPOX 1 0.05 1.33 1
13 INT278940 LEP Positive_regulation of Gene_expression of IL8 1 0.34 1.68 0.96
14 INT116930 OPRK1 Positive_regulation of Binding of PTK2 1 0.28 0.35 0.93
15 INT128859 Positive_regulation of RXRA Regulation of Gene_expression of OPRM1 1 0.05 0.26 0.9
16 INT238642 Binding of TNF and Ada 1 0.03 0.86 0.84
17 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
18 INT19299 ANG Regulation of AVP 1 0.25 0 0.82
19 INT130948 Amt Regulation of Gene_expression of LEP 1 0.00 1.04 0.78
20 INT130949 Amt Regulation of LEP 1 0.00 1.04 0.77
21 INT158068 Positive_regulation of Pparg Positive_regulation of Positive_regulation of PTGS2 1 0.01 0.28 0.76
22 INT250959 Binding of HLA-B and SOD1 1 0.05 0.75 0.75
23 INT120848 Sp6 Positive_regulation of Gene_expression of Ndp 1 0.14 0.52 0.74
24 INT278958 LEP Positive_regulation of IL1B 1 0.33 1.91 0.74
25 INT214163 Binding of Lep and Nts 1 0.04 0.21 0.74
26 INT296097 Acsm3 Negative_regulation of SOD1 1 0.01 1.3 0.72
27 INT89009 Lep Positive_regulation of Cck 2 0.67 0.43 0.69
28 INT278956 LEP Regulation of Gene_expression of IL8 1 0.30 1.11 0.69
29 INT278968 LEP Regulation of Gene_expression of IL6 1 0.29 1.11 0.69
30 INT278951 LEP Regulation of Gene_expression of PTGER2 1 0.07 1.11 0.69
31 INT278965 LEP Positive_regulation of Gene_expression of NOS2 2 0.29 2.12 0.66
32 INT61798 Binding of NDP and POMC 2 0.22 0 0.66
33 INT114947 YY1 Positive_regulation of Gene_expression of RXRA 1 0.33 0.25 0.65
34 INT111936 Binding of PIK3CA and PTK2 1 0.19 0.67 0.65
35 INT111937 Binding of PIK3CG and PTK2 1 0.08 0.67 0.64
36 INT114951 PPARA Positive_regulation of Gene_expression of RXRA 1 0.34 0.25 0.64
37 INT153797 NUBPL Negative_regulation of PPARD 1 0.02 0.69 0.64
38 INT114949 NCOA1 Positive_regulation of Gene_expression of RXRA 1 0.13 0.24 0.61
39 INT165844 Binding of ATF4 and HSP90AB1 1 0.15 0.34 0.61
40 INT323773 Binding of Il6 and Lep 1 0.29 3.54 0.6
41 INT327323 Il10 Positive_regulation of Gene_expression of Ttpa 1 0.02 1.43 0.58
42 INT71110 Binding of MC1R and NDP 1 0.10 0 0.57
43 INT349083 Binding of Lep and Rtn1 1 0.09 1.68 0.57
44 INT91339 Binding of Lep and Cck 1 0.28 0.34 0.56
45 INT113162 Lep Positive_regulation of Positive_regulation of Insrr 1 0.03 0 0.55
46 INT253834 Cck Regulation of Lep 1 0.19 0.23 0.55
47 INT204087 IL1B Positive_regulation of Gene_expression of LEP 1 0.09 2.6 0.54
48 INT214160 Binding of Lep and Mc4r 1 0.29 1.31 0.53
49 INT214143 Binding of Lep and Pomc 1 0.27 1.2 0.53
50 INT274625 OPN1MW Positive_regulation of SOD1 1 0.19 0.29 0.5
51 INT162890 Negative_regulation of Binding of LEP and Tnf 1 0.03 0.49 0.48
52 INT162889 Binding of LEP and Tnf 1 0.03 0.49 0.48
53 INT116932 PTK2 Negative_regulation of Positive_regulation of MAPK8 1 0.35 0.17 0.48
54 INT116935 Positive_regulation of OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.47
55 INT155881 Binding of CDX2 and KRAS 1 0.40 1.51 0.47
56 INT116939 OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.46
57 INT19297 ANG Positive_regulation of AVP 1 0.28 0 0.46
58 INT116928 PTK2 Positive_regulation of JUN 1 0.20 0.15 0.46
59 INT168445 Positive_regulation of C2 Positive_regulation of Positive_regulation of Dcn 1 0.14 0.66 0.46
60 INT132509 Binding of LEP and Cck 1 0.13 0.16 0.45
61 INT147404 NDP Positive_regulation of MC1R 1 0.22 0.25 0.45
62 INT241914 SOD1 Positive_regulation of Ros1 1 0.00 0.76 0.44
63 INT279360 ADA Negative_regulation of Gene_expression of IFNG 1 0.06 0.51 0.44
64 INT107703 PPARG Regulation of Gene_expression of CPOX 1 0.16 0.15 0.41
65 INT323880 Binding of BMI1 and LEP 1 0.02 3.97 0.41
66 INT61799 Negative_regulation of Binding of NDP and POMC 1 0.20 0 0.41
67 INT19298 ANG Regulation of OXT 1 0.07 0 0.41
68 INT316493 Il6 Positive_regulation of Il11ra1 1 0.64 1.69 0.4
69 INT120894 Binding of Gp1ba and Vwf 1 0.00 1.38 0.4
70 INT83171 Cck Regulation of Lep 1 0.30 0.09 0.4
71 INT184135 Il11ra1 Positive_regulation of Stat3 1 0.20 0.3 0.4
72 INT97395 Lep Positive_regulation of Stat3 1 0.67 0.42 0.4
73 INT340297 Ea1 Positive_regulation of Negative_regulation of Peg10 1 0.00 0 0.39
74 INT184092 Il11ra1 Positive_regulation of Jak1 1 0.17 0.3 0.39
75 INT143747 Binding of IL6 and LEP 2 0.04 4.05 0.38
76 INT250956 Positive_regulation of Binding of HLA-B and SOD1 1 0.07 0.38 0.38
77 INT151698 Binding of RNF130 and Vwf 1 0.04 0.29 0.37
78 INT300488 Binding of CRP and LEP 1 0.46 2.03 0.37
79 INT84887 APC Negative_regulation of Gene_expression of PPARD 1 0.36 0.55 0.37
80 INT226785 Angpt2 Positive_regulation of Localization of Lep 1 0.01 1.65 0.36
81 INT278966 MAPK14 Positive_regulation of Gene_expression of LEP 1 0.16 0.62 0.36
82 INT278949 JAK3 Positive_regulation of Gene_expression of LEP 1 0.42 0.63 0.36
83 INT279369 Binding of ADA and Ifx 1 0.29 0.27 0.35
84 INT107726 BIRC2 Regulation of ASIP 1 0.03 0.24 0.35
85 INT323885 LEP Regulation of Gene_expression of NOS2 1 0.26 1.07 0.35
86 INT213484 Binding of Lep and Pik3c3 1 0.01 0 0.35
87 INT327308 Binding of Elavl1 and Ttpa 1 0.02 1.73 0.34
88 INT323352 Binding of F8 and VWF 5 0.08 2.22 0.33
89 INT285558 Binding of Il11ra1 and Il27 1 0.05 1.1 0.33
90 INT207184 Binding of Adipoq and Lep 1 0.25 2.45 0.33
91 INT333993 Binding of Vcam1 and Vwf 1 0.00 1.32 0.33
92 INT122169 AKR1C3 Regulation of PPARG 1 0.45 0.26 0.33
93 INT323870 LEP Regulation of Gene_expression of MMP13 1 0.21 1.76 0.33
94 INT303993 Lep Positive_regulation of Gene_expression of IL2 1 0.15 0.24 0.33
95 INT116292 Gm9662 Negative_regulation of Pparg 1 0.00 0 0.33
96 INT116291 Gm9662 Negative_regulation of Positive_regulation of Pparg 1 0.00 0 0.32
97 INT105873 Ins1 Negative_regulation of Positive_regulation of Lep 1 0.27 0.67 0.31
98 INT278942 LEP Regulation of IL6 1 0.29 0.61 0.31
99 INT278939 LEP Regulation of IL8 1 0.13 0.61 0.31
100 INT213485 Lep Positive_regulation of Localization of Grin2a 1 0.19 0 0.31
101 INT148556 PPARG Regulation of Gene_expression of PPARA 1 0.30 1.2 0.31
102 INT333453 Binding of PPARA and RXRA 1 0.02 0 0.31
103 INT122168 AKR1C1 Regulation of PPARG 1 0.12 0.25 0.31
104 INT278969 LEP Regulation of PTGER2 1 0.03 0.6 0.31
105 INT105874 Lep Negative_regulation of Positive_regulation of Ins1 1 0.27 0.67 0.31
106 INT226989 Lias Regulation of Gene_expression of Lep 1 0.10 0.91 0.3
107 INT118300 Vwf Positive_regulation of Crp 1 0.00 0.87 0.3
108 INT278961 IL6 Regulation of Gene_expression of LEP 1 0.29 0.89 0.3
109 INT303983 Lep Positive_regulation of CXCL10 1 0.06 0.31 0.29
110 INT333886 Binding of Lep and Positive_regulation of Gene_expression of Nos2 1 0.39 0.73 0.29
111 INT303998 Lep Positive_regulation of Localization of IL1RAPL1 1 0.04 0.31 0.29
112 INT333887 Binding of Lep and Positive_regulation of Gene_expression of Il1 1 0.17 0.73 0.29
113 INT303995 Lep Positive_regulation of PSME1 1 0.09 0.32 0.29
114 INT57498 Vwf Positive_regulation of F8 1 0.00 0.36 0.29
115 INT303984 Lep Positive_regulation of Gene_expression of IL8 1 0.06 0.85 0.28
116 INT132426 Binding of F13A1 and Vwf 1 0.01 1.86 0.28
117 INT327337 MIR29A Negative_regulation of Ttpa 1 0.04 1.14 0.28
118 INT159201 Binding of Ppard and Ppara 1 0.01 0.68 0.28
119 INT100531 Cck Positive_regulation of Lep 1 0.70 0.15 0.26
120 INT110373 CYP4A11 Positive_regulation of PPARG 1 0.00 0.94 0.26
121 INT228611 Binding of DNMT3B and LEP 1 0.04 0 0.25
122 INT242215 Binding of ANG and OLR1 1 0.02 1.63 0.25
123 INT218732 Lep Regulation of Gene_expression of Trh 1 0.19 0.18 0.25
124 INT261375 Binding of Nsdhl and Pparg 1 0.05 1.03 0.25
125 INT130056 PPARG Positive_regulation of CAV1 1 0.02 0.53 0.25
126 INT190052 Binding of Cdx2 and Ebp 1 0.08 0.82 0.24
127 INT125748 Binding of LEP and Gh 1 0.00 0.52 0.24
128 INT130060 PPARG Positive_regulation of Positive_regulation of Egr1 1 0.22 0.46 0.24
129 INT183247 ADA Negative_regulation of ADORA1 1 0.01 0 0.23
130 INT306795 Binding of LEP and SFTPD 1 0.08 1.13 0.23
131 INT303988 Lep Positive_regulation of Gene_expression of ISYNA1 1 0.06 0.55 0.23
132 INT323883 BMI1 Regulation of LEP 1 0.02 2.39 0.23
133 INT17088 Binding of Ttpa and C9orf3 2 0.38 0.7 0.22
134 INT316491 Socs3 Positive_regulation of Il11ra1 1 0.45 0.92 0.22
135 INT102937 Gnrh1 Positive_regulation of Gene_expression of Lep 1 0.50 0 0.22
136 INT110653 Lep Regulation of Localization of Cck 1 0.06 0.22 0.22
137 INT20310 Binding of Hnf1a and Positive_regulation of Transcription of Cyp2e1 1 0.02 0 0.21
138 INT132680 HNF1A Positive_regulation of Gene_expression of UGT1A6 1 0.30 0.08 0.21
139 INT269180 LEP Positive_regulation of Localization of TNF 1 0.01 0.99 0.21
140 INT115148 PPARG Negative_regulation of Gene_expression of INSIG2 1 0.01 0.34 0.21
141 INT283858 Binding of PTK2 and APOA5 1 0.00 0.67 0.21
142 INT323873 LEP Regulation of Gene_expression of TIMP2 1 0.31 0.63 0.21
143 INT207185 Binding of Bmi1 and Lep 1 0.01 1.7 0.21
144 INT132679 HNF1A Regulation of Gene_expression of UGT1A6 1 0.16 0.08 0.21
145 INT222482 Lep Positive_regulation of Localization of Gh1 1 0.02 1.02 0.2
146 INT304001 Lep Negative_regulation of ICAM3 1 0.07 0.35 0.2
147 INT102743 Binding of SEPT5 and Vwf 1 0.01 0.35 0.2
148 INT189553 DCN Negative_regulation of Transcription of VEGFA 1 0.06 0.78 0.2
149 INT178086 Binding of EDNRA and PTK2 1 0.07 0.82 0.2
150 INT333889 Lep Regulation of Col7a1 1 0.04 0.41 0.2
151 INT303979 Lep Positive_regulation of ITGB2 1 0.11 0.35 0.2
152 INT256576 Lep Regulation of Localization of Ins1 1 0.57 2.08 0.2
153 INT303991 Lep Negative_regulation of SELL 1 0.04 0.35 0.2
154 INT217661 LEP Positive_regulation of INS 2 0.25 1.85 0.19
155 INT327814 Rab8a Regulation of Regulation of Lep 1 0.01 0.15 0.19
156 INT327813 Rab8a Regulation of Lep 1 0.01 0.15 0.19
157 INT303964 Lep Positive_regulation of Icam1 1 0.24 0.35 0.19
158 INT28562 SOD1 Negative_regulation of Pacs1 1 0.03 2.63 0.19
159 INT333888 Lep Regulation of Localization of GAG 1 0.68 0.38 0.19
160 INT327317 Ttpa Negative_regulation of Elavl1 1 0.02 0.45 0.19
161 INT327312 Positive_regulation of Ttpa Negative_regulation of Elavl1 1 0.03 0.45 0.19
162 INT251492 Binding of HSPD1 and SOD1 1 0.02 1.45 0.18
163 INT250949 Binding of KIR3DL2 and SOD1 1 0.24 0.55 0.18
164 INT214170 Binding of DST and Lep 1 0.02 0.17 0.18
165 INT303981 Lep Positive_regulation of Localization of CXCL1 1 0.02 0.34 0.18
166 INT178092 EDN3 Positive_regulation of PTK2 1 0.01 1.02 0.17
167 INT81296 Positive_regulation of Pparg Regulation of Gene_expression of Hmox1 1 0.25 0.17 0.17
168 INT327327 Ttpa Negative_regulation of Il3 1 0.01 0.4 0.17
169 INT226988 Lias Positive_regulation of Localization of Lep 1 0.08 0.3 0.17
170 INT323757 Negative_regulation of ACE2 Negative_regulation of ANG 1 0.18 1.73 0.17
171 INT81297 Positive_regulation of Pparg Regulation of Gene_expression of Nos2 1 0.23 0.17 0.17
172 INT179846 Il11 Regulation of Positive_regulation of Rps6 1 0.04 0.07 0.17
173 INT178073 EDN1 Positive_regulation of PTK2 1 0.03 1.02 0.17
174 INT184103 Binding of Socs3 and Il11ra1 1 0.12 0 0.17
175 INT323756 Negative_regulation of ACE2 Positive_regulation of ANG 1 0.19 1.73 0.17
176 INT86892 Glp2r Regulation of Gene_expression of Cdx2 1 0.38 0 0.17
177 INT303967 Lep Positive_regulation of Gene_expression of Icam1 1 0.24 0.58 0.16
178 INT301907 Binding of THBD and VWF 1 0.02 1.71 0.16
179 INT333447 Binding of SMAD2 and RXRA 1 0.04 0 0.16
180 INT303980 Lep Positive_regulation of Transcription of IL2 1 0.10 0.24 0.16
181 INT206070 ANG Positive_regulation of Transcription of IL6 1 0.05 1.5 0.15
182 INT106506 Binding of Pparg and Ptgds 1 0.42 0.31 0.14
183 INT327326 Binding of Mapkapk2 and Ttpa 1 0.02 0.34 0.14
184 INT217667 LEP Negative_regulation of Localization of INS 1 0.15 1.18 0.14
185 INT147727 Phosphorylation of PTK2 Regulation of Positive_regulation of RAC1 1 0.34 0.32 0.14
186 INT117913 CREM Positive_regulation of Negative_regulation of BIRC2 1 0.15 0.81 0.14
187 INT217664 LEP Negative_regulation of INS 1 0.15 1.18 0.14
188 INT147726 Phosphorylation of PTK2 Regulation of Positive_regulation of PIK3CA 1 0.09 0.32 0.14
189 INT252575 Rpe Negative_regulation of SOD1 1 0.03 2.39 0.14
190 INT323877 LEP Positive_regulation of SOAT1 1 0.20 1.26 0.14
191 INT276228 Nrtim1 Positive_regulation of PPARG 1 0.01 2.18 0.14
192 INT327319 Binding of Mapk14 and Ttpa 1 0.01 0.34 0.14
193 INT102885 Binding of ANG and ACE 2 0.17 0.37 0.13
194 INT115140 PPARG Positive_regulation of EGR1 1 0.36 0.45 0.13
195 INT139975 Binding of LEP and Prl 1 0.02 0.49 0.13
196 INT109410 RASGRP1 Regulation of Gene_expression of PPARG 1 0.03 0.76 0.13
197 INT115145 PPARG Positive_regulation of TFAM 1 0.04 0.45 0.13
198 INT281911 Binding of ANG and MAS1 1 0.05 0.39 0.13
199 INT328060 LEP Positive_regulation of FAAH 1 0.06 0.7 0.13
200 INT346714 LEP Regulation of GALP 1 0.06 0.08 0.13

Single Events

The table below shows the top 100 pain related interactions that have been reported for placenta development. They are ordered first by their pain relevance and then by number of times they were reported in placenta development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31
2 INT67613 Positive_regulation of PPARG 94 0.70 69.15 34.38
3 INT67610 Positive_regulation of Pparg 53 0.70 31.91 25.2
4 INT101483 Gene_expression of Lep 159 0.78 104.77 25.12
5 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76
6 INT73625 Gene_expression of PPARG 108 0.78 104.85 21.42
7 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22
8 INT67608 Gene_expression of Pparg 41 0.78 25.09 19.53
9 INT9900 Positive_regulation of Vwf 80 0.69 51.85 18.13
10 INT62681 Negative_regulation of LEP 93 0.59 66.97 15.77
11 INT75908 Regulation of LEP 77 0.60 60.16 15.19
12 INT32802 Negative_regulation of Ada 21 0.57 4.03 14.87
13 INT67611 Positive_regulation of Pparg 39 0.69 18.33 13.23
14 INT73641 Regulation of Lep 45 0.62 26.2 12.59
15 INT31990 Positive_regulation of SOD1 124 0.69 67.79 12.52
16 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4
17 INT126743 Positive_regulation of Gene_expression of LEP 61 0.66 50.02 11.17
18 INT82079 Positive_regulation of Lep 79 0.70 40 11.07
19 INT79685 Positive_regulation of Gene_expression of Pparg 17 0.70 14.63 11.03
20 INT11238 Positive_regulation of ADA 33 0.70 39.7 9.98
21 INT101481 Positive_regulation of Lep 81 0.69 62.59 9.95
22 INT29740 Gene_expression of ANG 55 0.78 24.53 9.86
23 INT82078 Negative_regulation of Lep 54 0.59 20.47 9.38
24 INT9899 Gene_expression of Vwf 91 0.74 45.06 9.13
25 INT67612 Binding of PPARG 38 0.48 22.67 8.94
26 INT82082 Localization of Lep 63 0.81 26.41 8.56
27 INT75907 Binding of LEP 53 0.46 46.65 8.44
28 INT60034 Positive_regulation of VWF 40 0.68 30.42 8.15
29 INT4663 Positive_regulation of Ada 17 0.69 9.48 7.93
30 INT103399 Positive_regulation of Positive_regulation of Pparg 11 0.66 7 7.36
31 INT64523 Binding of Ndp 10 0.33 2.72 7.29
32 INT14903 Negative_regulation of SOD1 81 0.57 42.02 6.91
33 INT61114 Gene_expression of Ppard 23 0.75 14.98 6.62
34 INT67609 Binding of Pparg 17 0.46 9.53 6.06
35 INT55655 Gene_expression of DCN 17 0.75 7.98 5.98
36 INT100078 Positive_regulation of Positive_regulation of PPARG 11 0.70 3.6 5.86
37 INT146594 Negative_regulation of Gene_expression of LEP 25 0.42 18.88 5.71
38 INT29674 Gene_expression of Ada 16 0.78 4.59 5.69
39 INT101482 Negative_regulation of Lep 53 0.54 33.59 5.65
40 INT30206 Negative_regulation of ADA 17 0.59 10.03 5.63
41 INT69944 Positive_regulation of Ndp 7 0.38 4.81 5.6
42 INT32458 Gene_expression of VWF 57 0.78 28.97 5.56
43 INT65356 Localization of LEP 46 0.79 41.17 5.43
44 INT91338 Binding of Lep 31 0.48 26.86 5.39
45 INT163913 Gene_expression of Il11ra1 18 0.69 12.62 5.34
46 INT102935 Regulation of Lep 31 0.60 18.47 5.24
47 INT10888 Binding of Vwf 32 0.46 22.87 5.21
48 INT68202 Gene_expression of ADA 26 0.68 23.15 5.18
49 INT36256 Regulation of Ada 9 0.62 4.99 5.07
50 INT9767 Negative_regulation of Ada 5 0.55 0.06 5.06
51 INT185877 Negative_regulation of Gene_expression of DCN 3 0.33 2.37 4.85
52 INT74447 Gene_expression of Vwf 39 0.76 21.96 4.66
53 INT85301 Gene_expression of Ndp 6 0.52 4.19 4.5
54 INT97391 Binding of Lep 18 0.48 8.97 4.47
55 INT73626 Positive_regulation of Gene_expression of PPARG 22 0.70 18.82 4.4
56 INT79692 Negative_regulation of PPARG 24 0.59 16 4.31
57 INT87345 Phosphorylation of PTK2 110 0.82 59.39 4.28
58 INT163581 Localization of Lep 27 0.79 18.99 4.08
59 INT72936 Gene_expression of Pparg 39 0.77 19.01 4.02
60 INT134590 Localization of ADA 7 0.65 8.43 3.96
61 INT112070 Negative_regulation of Gene_expression of Pparg 6 0.59 3.72 3.96
62 INT119606 Regulation of Gene_expression of LEP 17 0.45 17.96 3.75
63 INT174054 Positive_regulation of Gene_expression of Lep 25 0.69 21.3 3.72
64 INT10146 Negative_regulation of Vwf 27 0.40 17.11 3.69
65 INT84891 Gene_expression of PPARD 10 0.78 6.8 3.64
66 INT78845 Binding of Pparg 16 0.44 11.67 3.53
67 INT82077 Positive_regulation of Gene_expression of Lep 32 0.70 17.9 3.5
68 INT130351 Positive_regulation of Vwf 18 0.59 5.99 3.48
69 INT72798 Binding of ADA 12 0.47 7.84 3.39
70 INT279383 Negative_regulation of Ttpa 2 0.06 16.02 3.37
71 INT102034 Positive_regulation of Ppard 10 0.69 3.97 3.17
72 INT19392 Gene_expression of Ada 9 0.77 7.4 3.17
73 INT110956 Negative_regulation of Positive_regulation of Pparg 5 0.41 3.68 3.11
74 INT34604 Binding of Ada 11 0.31 4.15 3.1
75 INT84890 Negative_regulation of PPARD 7 0.59 3.27 3.1
76 INT112071 Regulation of Gene_expression of Pparg 4 0.62 4.62 3.09
77 INT9766 Positive_regulation of Ada 2 0.47 0.4 3.09
78 INT55409 Localization of VWF 17 0.80 8.99 3.06
79 INT99187 Negative_regulation of Positive_regulation of PPARG 5 0.42 5.07 2.99
80 INT131494 Regulation of ADA 8 0.52 7.37 2.97
81 INT322473 Localization of DCN 1 0.03 0.76 2.9
82 INT112758 Binding of Ppard 7 0.37 3.6 2.87
83 INT10893 Binding of VWF 27 0.47 25.02 2.82
84 INT10516 Localization of Vwf 30 0.79 7.54 2.77
85 INT53755 Positive_regulation of Dcn 8 0.43 2.91 2.74
86 INT163911 Negative_regulation of Il11ra1 4 0.39 6.43 2.73
87 INT97443 Positive_regulation of Positive_regulation of LEP 13 0.50 11.91 2.65
88 INT31989 Binding of SOD1 43 0.47 19.38 2.55
89 INT327227 Gene_expression of Ttpa 1 0.08 12.08 2.52
90 INT94010 Positive_regulation of Localization of VWF 9 0.70 4.23 2.5
91 INT102033 Negative_regulation of Ppard 5 0.37 4.14 2.48
92 INT322648 Gene_expression of Pbrm1 1 0.62 39.51 2.43
93 INT103487 Positive_regulation of Positive_regulation of Lep 9 0.67 4.08 2.38
94 INT68087 Regulation of Vwf 9 0.39 8.06 2.36
95 INT89250 Positive_regulation of Il11ra1 8 0.63 3.99 2.27
96 INT81312 Positive_regulation of Gene_expression of Ada 2 0.50 1.58 2.26
97 INT163912 Binding of Il11ra1 5 0.33 5.06 2.22
98 INT81294 Negative_regulation of Positive_regulation of Pparg 7 0.58 4.39 2.2
99 INT101516 Positive_regulation of PPARD 8 0.49 4.75 2.19
100 INT78844 Regulation of Pparg 6 0.41 4 2.19
101 INT82081 Regulation of Gene_expression of Lep 11 0.53 7.78 2.12
102 INT83392 Transcription of Lep 6 0.54 5.07 2.04
103 INT96764 Positive_regulation of Gene_expression of SOD1 36 0.61 16.55 1.99
104 INT61806 Regulation of Negative_regulation of Ada 1 0.30 0.63 1.89
105 INT61802 Binding of NDP 6 0.28 0 1.85
106 INT82083 Negative_regulation of Gene_expression of Lep 12 0.56 8.07 1.75
107 INT29739 Positive_regulation of ANG 11 0.69 4.37 1.75
108 INT37954 Negative_regulation of Dcn 6 0.41 0.62 1.72
109 INT102893 Positive_regulation of Gene_expression of ANG 10 0.69 5.62 1.71
110 INT116110 Positive_regulation of PTK2 20 0.66 10.53 1.64
111 INT322472 Negative_regulation of Localization of DCN 1 0.02 0.47 1.64
112 INT117438 Positive_regulation of Gene_expression of Pparg 11 0.69 8 1.63
113 INT79691 Regulation of Gene_expression of PPARG 10 0.50 10.44 1.62
114 INT34605 Localization of Ada 7 0.80 0.13 1.61
115 INT95056 Positive_regulation of Gene_expression of Ppard 5 0.52 3.84 1.6
116 INT117915 Gene_expression of BIRC2 8 0.63 6.74 1.59
117 INT27293 Regulation of SOD1 21 0.53 15.73 1.55
118 INT79690 Negative_regulation of Gene_expression of PPARG 10 0.59 10.48 1.55
119 INT111946 Positive_regulation of Phosphorylation of PTK2 8 0.66 11.5 1.53
120 INT84889 Positive_regulation of Gene_expression of PPARD 4 0.70 2.94 1.49
121 INT128865 Regulation of Positive_regulation of RXRA 1 0.08 0.64 1.48
122 INT128863 Positive_regulation of RXRA 1 0.12 0.63 1.47
123 INT137927 Positive_regulation of Positive_regulation of Ada 1 0.03 1.31 1.47
124 INT84888 Binding of PPARD 5 0.48 2.82 1.45
125 INT214115 Regulation of Gene_expression of Lep 9 0.61 7.37 1.44
126 INT30277 Protein_catabolism of Ada 3 0.52 0.9 1.42
127 INT181873 Regulation of Localization of ADA 1 0.07 1.98 1.41
128 INT251834 Negative_regulation of Gene_expression of ANG 5 0.59 3.95 1.38
129 INT163915 Positive_regulation of Gene_expression of Il11ra1 2 0.41 1.84 1.37
130 INT132495 Negative_regulation of Gene_expression of Ppard 4 0.44 2.64 1.28
131 INT327244 Negative_regulation of Gene_expression of Ttpa 1 0.06 5.23 1.22
132 INT87343 Negative_regulation of Phosphorylation of PTK2 34 0.59 18.38 1.19
133 INT167270 Negative_regulation of Gene_expression of Lep 13 0.55 5.48 1.19
134 INT87346 Binding of PTK2 6 0.37 4.03 1.18
135 INT213465 Transcription of Lep 4 0.68 2.11 1.15
136 INT327285 Phosphorylation of Ttpa 1 0.09 4.72 1.15
137 INT61800 Negative_regulation of Binding of NDP 3 0.24 0 1.14
138 INT192073 Positive_regulation of Gene_expression of ADA 8 0.47 10.35 1.12
139 INT253813 Regulation of Negative_regulation of Lep 2 0.45 1.01 1.12
140 INT82084 Positive_regulation of Localization of Lep 11 0.70 4.65 1.11
141 INT110259 Negative_regulation of Vwf 6 0.42 3.3 1.1
142 INT19303 Regulation of ANG 3 0.62 1.08 1.09
143 INT163910 Negative_regulation of Gene_expression of Il11ra1 3 0.39 2.11 1.08
144 INT79689 Regulation of PPARG 10 0.62 8.04 1.07
145 INT159543 Localization of SOD1 29 0.75 8.62 1.06
146 INT238636 Regulation of Ada 2 0.15 1.12 1.06
147 INT87342 Regulation of Phosphorylation of PTK2 3 0.59 5.7 1.05
148 INT64525 Negative_regulation of Binding of Ndp 4 0.10 0.31 1.03
149 INT98817 Regulation of Pparg 3 0.26 1.62 1.03
150 INT129398 Negative_regulation of Gene_expression of SOD1 22 0.43 7.11 1.02
151 INT86889 Gene_expression of Cdx2 8 0.60 4.23 1.02
152 INT112759 Negative_regulation of Binding of Ppard 2 0.39 2.08 0.99
153 INT157573 Localization of Vwf 9 0.69 2.93 0.97
154 INT238637 Binding of Ada 2 0.26 1.01 0.94
155 INT118538 Binding of ANG 5 0.47 3.02 0.92
156 INT107714 Localization of PPARG 4 0.73 0.88 0.91
157 INT105070 Localization of Ndp 1 0.57 0.93 0.91
158 INT116459 Negative_regulation of VWF 8 0.58 5.66 0.89
159 INT87344 Gene_expression of PTK2 90 0.78 59.03 0.87
160 INT117308 Negative_regulation of Localization of Lep 3 0.59 2.16 0.86
161 INT103400 Transcription of Pparg 2 0.67 3.15 0.85
162 INT333883 Positive_regulation of Positive_regulation of Lep 2 0.46 1.06 0.83
163 INT84892 Negative_regulation of Gene_expression of PPARD 2 0.43 1.85 0.83
164 INT68200 Protein_catabolism of Ada 2 0.44 0.68 0.83
165 INT87837 Binding of Dcn 4 0.35 1.28 0.82
166 INT109079 Negative_regulation of ANG 4 0.57 2.2 0.8
167 INT87838 Gene_expression of Dcn 7 0.75 0.74 0.79
168 INT85300 Regulation of Ndp 1 0.23 0.42 0.79
169 INT132127 Positive_regulation of Rps6 1 0.49 0.32 0.79
170 INT87341 Regulation of Gene_expression of PTK2 2 0.62 8.34 0.77
171 INT279366 Positive_regulation of Localization of ADA 2 0.42 4.37 0.76
172 INT82080 Regulation of Localization of Lep 2 0.45 1.36 0.76
173 INT88957 Positive_regulation of Gene_expression of VWF 12 0.42 7.34 0.75
174 INT156533 Transcription of LEP 9 0.69 4.35 0.74
175 INT213471 Positive_regulation of Localization of Lep 4 0.48 2.65 0.74
176 INT150037 Regulation of Gene_expression of Vwf 2 0.14 1.99 0.74
177 INT9898 Positive_regulation of Gene_expression of Vwf 9 0.49 4.47 0.71
178 INT28561 Regulation of Gene_expression of SOD1 9 0.61 2.83 0.71
179 INT111399 Negative_regulation of DCN 2 0.18 1.74 0.7
180 INT130350 Negative_regulation of Positive_regulation of Vwf 1 0.36 0.22 0.7
181 INT327246 Binding of Ttpa 1 0.05 2.48 0.7
182 INT40605 Negative_regulation of Negative_regulation of Ada 1 0.32 0 0.7
183 INT110089 Positive_regulation of Binding of PPARG 1 0.70 1.04 0.7
184 INT130352 Positive_regulation of Positive_regulation of Vwf 1 0.43 0.22 0.7
185 INT25283 Negative_regulation of Positive_regulation of Vwf 2 0.21 2.7 0.69
186 INT184053 Regulation of Il11ra1 3 0.16 2.03 0.68
187 INT278334 Negative_regulation of Hsp90ab1 3 0.30 4.34 0.68
188 INT94148 Positive_regulation of Binding of Pparg 2 0.43 1.16 0.66
189 INT98208 Regulation of Vwf 3 0.08 1.14 0.63
190 INT114959 Gene_expression of RXRA 2 0.50 1.06 0.63
191 INT116288 Negative_regulation of Pparg 4 0.42 1.69 0.62
192 INT87836 Localization of Dcn 3 0.68 0.6 0.62
193 INT210028 Protein_catabolism of ADA 1 0.07 0.13 0.62
194 INT101484 Regulation of Positive_regulation of Lep 3 0.45 1.68 0.61
195 INT114960 Positive_regulation of Gene_expression of RXRA 1 0.32 0.24 0.61
196 INT71114 Regulation of NDP 1 0.12 0 0.61
197 INT37953 Regulation of Dcn 3 0.39 0.51 0.6
198 INT345957 Positive_regulation of Binding of Lep 2 0.38 2.03 0.6
199 INT165847 Positive_regulation of HSP90AB1 1 0.60 0.31 0.6
200 INT135690 Negative_regulation of Negative_regulation of Dcn 1 0.38 0 0.6
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