GO:0002116

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Name semaphorin receptor complex
Categary Component
Go Slim No
Go Link GO:0002116
Unique Molecular Interactions 47
Total Molecular Interactions 97
Total Single Events 269
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for semaphorin receptor complex. They are ordered first by their pain relevance and then by number of times they were reported for semaphorin receptor complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT260833 Binding of NRP2 and Flt1 1 0.00 3.61 1.22
2 INT168185 Binding of PLXNA2 and MRI1 1 0.25 0.78 1.08
3 INT260842 Binding of NRP2 and Kdr 1 0.00 2.28 0.85
4 INT260832 Binding of NRP2 and Nrp1 1 0.00 2.32 0.7
5 INT260821 NRP2 Positive_regulation of Gene_expression of TNF 1 0.01 1.48 0.56
6 INT97949 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of CDC42 1 0.06 0.72 0.51
7 INT97952 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of AKT1 1 0.03 0.72 0.51
8 INT97950 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of ST3GAL3 1 0.02 0.72 0.5
9 INT36340 Binding of NRP2 and Penk 1 0.04 0.07 0.39
10 INT304339 Negative_regulation of CD79A Positive_regulation of NRP2 1 0.06 0.86 0.33
11 INT304338 CD79A Positive_regulation of NRP2 1 0.08 0.84 0.32
12 INT260841 Il6 Positive_regulation of Localization of NRP2 1 0.00 0.7 0.29
13 INT355038 NRP1 Negative_regulation of CKAP4 1 0.02 1.23 0.29
14 INT260837 NRP2 Negative_regulation of Negative_regulation of Bcl2 1 0.00 0.9 0.28
15 INT260840 NRP2 Positive_regulation of Gene_expression of Bcl2 1 0.00 0.85 0.24
16 INT260835 NRP2 Positive_regulation of Eif2ak3 1 0.00 0.73 0.23
17 INT260844 NRP2 Positive_regulation of Akt1 1 0.00 0.73 0.22
18 INT172232 CALCRL Positive_regulation of Gene_expression of NRP1 1 0.02 0.07 0.17
19 INT172237 TAS2R14 Positive_regulation of Gene_expression of NRP1 1 0.01 0.07 0.17
20 INT146997 Binding of PLXNA3 and RLS 1 0.36 0.47 0.1
21 INT224026 P2RY6 Positive_regulation of NRP2 1 0.10 0.98 0.1
22 INT173051 Binding of VEGFA and NRP1 16 0.44 1.29 0.04
23 INT173053 Binding of VEGFA and NRP2 3 0.12 1.36 0.04
24 INT173056 Binding of NRP2 and NRP1 2 0.24 0.61 0.04
25 INT265771 NRP1 Positive_regulation of VEGFA 1 0.46 0 0.04
26 INT311925 Binding of NRP2 and SEMA3A 1 0.26 0.06 0.04
27 INT265764 NRP1 Positive_regulation of FLT1 1 0.45 0 0.04
28 INT315915 VEGFA Regulation of NRP1 1 0.22 0.32 0.04
29 INT265772 Binding of KDR and NRP1 1 0.29 0 0.04
30 INT311926 Binding of NRP1 and SEMA3A 1 0.26 0.48 0.04
31 INT265749 Binding of FLT1 and NRP1 1 0.43 0 0.04
32 INT315912 VEGFA Regulation of NRP2 1 0.04 0.32 0.04
33 INT311927 AASDH Positive_regulation of NRP2 1 0.02 0.1 0.03
34 INT265744 VEGFA Regulation of Localization of NRP1 1 0.25 0 0
35 INT276285 Binding of SEPHS1 and PLXNA3 1 0.00 0.41 0
36 INT265767 Positive_regulation of Binding of VEGFA and NRP1 1 0.46 0 0
37 INT173054 NRP1 Positive_regulation of KDR 1 0.08 0.34 0
38 INT311948 Binding of NRP1 and Plxna3 1 0.05 0.26 0
39 INT265752 NRP1 Negative_regulation of Gene_expression of FLT1 1 0.33 0 0
40 INT265765 Binding of NRP1 and GOPC 1 0.13 0 0
41 INT265737 Binding of AR and NRP1 1 0.10 0 0
42 INT265751 NRP1 Negative_regulation of Localization of FLT1 1 0.33 0 0
43 INT265756 Positive_regulation of Binding of AR and NRP1 1 0.10 0 0
44 INT265757 Regulation of Binding of VEGFA and NRP1 1 0.41 0 0
45 INT265738 NRP1 Positive_regulation of KLKB1 1 0.03 0 0
46 INT265741 Negative_regulation of Binding of FLT1 and NRP1 1 0.38 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for semaphorin receptor complex. They are ordered first by their pain relevance and then by number of times they were reported in semaphorin receptor complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT32256 Gene_expression of PLXNA3 11 0.75 7.8 4.92
2 INT21156 Binding of PLXNA3 21 0.36 7.95 3.3
3 INT168188 Gene_expression of PLXNA2 13 0.58 9 2.73
4 INT82347 Regulation of PLXNA3 5 0.60 4.59 2.45
5 INT36338 Gene_expression of NRP2 29 0.67 6.47 2.4
6 INT64609 Negative_regulation of PLXNA3 5 0.57 3.64 1.94
7 INT196158 Binding of NRP2 16 0.06 7.03 1.73
8 INT113676 Gene_expression of NRP1 22 0.72 10.81 1.71
9 INT16622 Positive_regulation of PLXNA3 6 0.67 5.2 1.69
10 INT149291 Negative_regulation of NRP1 5 0.40 2.64 0.84
11 INT196182 Localization of NRP2 9 0.46 3.61 0.8
12 INT62760 Localization of PLXNA3 3 0.78 2.06 0.8
13 INT149298 Protein_catabolism of NRP1 2 0.82 1.52 0.77
14 INT168189 Positive_regulation of PLXNA2 1 0.20 0.49 0.75
15 INT139205 Binding of NRP1 27 0.45 4.34 0.71
16 INT265800 Localization of NRP1 14 0.75 3.66 0.69
17 INT342318 Localization of PLXNA2 1 0.25 0.75 0.67
18 INT97962 Negative_regulation of NRP2 2 0.08 0.91 0.5
19 INT248346 Binding of PLXNA2 4 0.29 1.38 0.46
20 INT112379 Positive_regulation of Gene_expression of NRP2 3 0.50 0.18 0.46
21 INT149293 Negative_regulation of Protein_catabolism of NRP1 1 0.05 0.93 0.44
22 INT143442 Positive_regulation of NRP1 11 0.57 2.62 0.3
23 INT264305 Negative_regulation of Gene_expression of NRP1 3 0.40 1.4 0.25
24 INT274104 Regulation of PLXNA2 2 0.33 2.66 0.25
25 INT248347 Negative_regulation of PLXNA2 1 0.38 0.24 0.22
26 INT311446 Negative_regulation of Gene_expression of PLXNA2 1 0.12 1.1 0.18
27 INT265792 Regulation of Localization of NRP1 1 0.22 0.21 0.13
28 INT265797 Regulation of Protein_catabolism of NRP1 1 0.51 0.21 0.13
29 INT203612 Positive_regulation of NRP2 2 0.33 0.49 0.12
30 INT143446 Positive_regulation of Gene_expression of NRP1 1 0.45 1.02 0.12
31 INT354592 Positive_regulation of Gene_expression of PLXNA2 1 0.04 0.37 0.07
32 INT354593 Regulation of Gene_expression of PLXNA2 1 0.04 0.34 0.05
33 INT235629 Phosphorylation of NRP1 2 0.76 0.81 0
34 INT196157 Regulation of NRP2 1 0.00 0.16 0
35 INT113675 Regulation of Gene_expression of NRP1 1 0.00 1.62 0
36 INT196170 Regulation of Gene_expression of NRP2 1 0.00 0.16 0
37 INT315923 Negative_regulation of Positive_regulation of NRP1 1 0.40 0.19 0
38 INT265785 Positive_regulation of Localization of NRP1 1 0.41 0 0
39 INT311944 Negative_regulation of Gene_expression of NRP2 1 0.39 0.17 0
40 INT265793 Regulation of NRP1 1 0.22 0 0
41 INT265798 Positive_regulation of Binding of NRP1 1 0.41 0 0
42 INT188898 Negative_regulation of Localization of PLXNA3 1 0.09 0.47 0
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