GO:0002326

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Name B cell lineage commitment
Categary Process
Go Slim No
Go Link GO:0002326
Unique Molecular Interactions 448
Total Molecular Interactions 562
Total Single Events 5427
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for B cell lineage commitment. They are ordered first by their pain relevance and then by number of times they were reported for B cell lineage commitment. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
3 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
4 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99
5 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
6 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
7 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
8 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
9 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
10 INT150864 RYBP Positive_regulation of Positive_regulation of Bcl2 1 0.01 0.66 0.86
11 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
12 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
13 INT218935 Cyp3a23/3a1 Regulation of Bcl2 1 0.00 1.08 0.74
14 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
15 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
16 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
17 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
18 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
19 INT322048 Prkdc Negative_regulation of Col7a1 1 0.00 0.45 0.5
20 INT302839 MIR15A Negative_regulation of Bcl2 1 0.15 1.41 0.47
21 INT238639 Cd86 Negative_regulation of Negative_regulation of Bcl2 1 0.01 0.97 0.46
22 INT112772 Binding of Bcl2 and SGSM3 1 0.02 0.69 0.45
23 INT116609 Lnpep Negative_regulation of Bcl2 1 0.05 0.62 0.43
24 INT116606 Lnpep Regulation of Gene_expression of Bcl2 1 0.07 0.62 0.43
25 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43
26 INT116607 Lnpep Negative_regulation of Gene_expression of Bcl2 1 0.10 0.62 0.43
27 INT309143 Dlat Positive_regulation of Bcl2 1 0.06 1.04 0.42
28 INT309152 Dlat Positive_regulation of Gene_expression of Bcl2 1 0.04 1.05 0.42
29 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38
30 INT155062 Csf2 Positive_regulation of Transcription of Bcl2 1 0.31 2.91 0.36
31 INT264555 IL15 Positive_regulation of Gene_expression of BCL2 1 0.02 0.92 0.35
32 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34
33 INT155060 Stat3 Negative_regulation of Bcl2 1 0.21 3.7 0.33
34 INT91814 Binding of TNF and TP53 1 0.14 2.2 0.32
35 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
36 INT166396 IFI27 Regulation of Gene_expression of TP53 1 0.19 0.41 0.31
37 INT242398 Cyp19a1 Positive_regulation of Bcl2 1 0.00 1.28 0.3
38 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 0.01 1.23 0.3
39 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3
40 INT163761 MDM2 Positive_regulation of Gene_expression of TP53 1 0.40 0.86 0.3
41 INT166952 LYRM4 Positive_regulation of Gene_expression of TP53 1 0.05 0.75 0.28
42 INT218928 Cyp3a23/3a1 Regulation of Transcription of Bcl2 1 0.00 0.56 0.28
43 INT260837 NRP2 Negative_regulation of Negative_regulation of Bcl2 1 0.00 0.9 0.28
44 INT286042 Binding of Tp53 and Wwox 1 0.04 2.05 0.28
45 INT216127 EGR1 Regulation of Transcription of TP53 1 0.06 0.21 0.28
46 INT302837 Binding of TNFRSF10D and Trp53 1 0.01 0.98 0.28
47 INT172905 Binding of Bad and Bcl2 3 0.08 6.46 0.27
48 INT306267 Binding of INCENP and TP53 1 0.02 0.83 0.27
49 INT216128 EGR1 Regulation of TP53 1 0.11 0.21 0.27
50 INT237927 BCL2 Positive_regulation of BAX 2 0.24 2.22 0.26
51 INT237928 BCL2 Positive_regulation of FAS 1 0.02 1.41 0.26
52 INT272157 Gh1 Negative_regulation of Bcl2 1 0.23 1.2 0.26
53 INT272158 Gh1 Regulation of Bcl2 1 0.15 1.2 0.26
54 INT352931 Prkaca Regulation of TP53 1 0.13 1.01 0.26
55 INT352930 Prkaca Regulation of Phosphorylation of TP53 1 0.13 1.02 0.26
56 INT125514 Positive_regulation of PRKDC Positive_regulation of Positive_regulation of NFKB1 1 0.07 0.44 0.26
57 INT237925 BCL2 Positive_regulation of Protein_catabolism of PARP1 1 0.02 1.42 0.26
58 INT182325 TP53 Negative_regulation of Transcription of Birc5 1 0.01 1.34 0.26
59 INT172975 Trp53 Positive_regulation of Cdkn1a 1 0.03 1.35 0.26
60 INT352893 PTGDS Regulation of TP53 1 0.16 1.02 0.26
61 INT125516 TP53 Regulation of GDF15 1 0.10 0.47 0.26
62 INT337086 Mif Negative_regulation of Localization of Trp53 1 0.16 1.64 0.25
63 INT337091 Mif Negative_regulation of Positive_regulation of Trp53 1 0.16 1.64 0.25
64 INT156879 Gene_expression of TP53 Negative_regulation of Positive_regulation of PDF 1 0.45 0.9 0.24
65 INT260840 NRP2 Positive_regulation of Gene_expression of Bcl2 1 0.00 0.85 0.24
66 INT181900 TP53 Negative_regulation of Gene_expression of NOS1 1 0.03 0.94 0.24
67 INT156881 TP53 Positive_regulation of Positive_regulation of PDF 1 0.49 0.89 0.24
68 INT229177 IFRD1 Regulation of TP53 1 0.13 0.68 0.23
69 INT302170 PTGER2 Positive_regulation of Gene_expression of BCL2 1 0.04 3.76 0.23
70 INT226902 Padi3 Regulation of Trp53 1 0.06 0.69 0.22
71 INT229178 TP53 Regulation of ICAM1 1 0.07 0.9 0.21
72 INT156882 Binding of TP53 and PDF 1 0.39 0.77 0.21
73 INT156880 TP53 Positive_regulation of Gene_expression of PDF 1 0.49 0.75 0.21
74 INT210887 Sst Positive_regulation of Gene_expression of Trp53 1 0.33 0.93 0.2
75 INT193787 Positive_regulation of CXCR4 Positive_regulation of Positive_regulation of TP53 1 0.03 0.71 0.19
76 INT142853 Binding of TP53 and WISP2 1 0.33 1.43 0.19
77 INT176133 AKT1 Regulation of BCL2 2 0.12 1.84 0.17
78 INT285026 Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
79 INT285022 Regulation of Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
80 INT349475 Regulation of Bax Regulation of Bcl2 1 0.07 1.35 0.17
81 INT155233 TXNIP Regulation of BCL2 1 0.23 0.15 0.17
82 INT285024 Bcl2 Regulation of Bak1 1 0.09 0.71 0.17
83 INT229203 Binding of Bcl2 and Cyp2c11 1 0.36 1.2 0.17
84 INT155068 Csf2 Negative_regulation of Bcl2 1 0.12 1.88 0.17
85 INT102804 NFKB1 Regulation of TP53 1 0.35 0.77 0.17
86 INT102803 NFKB1 Regulation of Gene_expression of TP53 1 0.35 0.77 0.17
87 INT91812 Binding of FASLG and TP53 1 0.04 1.1 0.16
88 INT347445 CD99 Positive_regulation of BCL2 1 0.17 0.95 0.16
89 INT91811 Binding of FAS and TP53 1 0.21 1.1 0.16
90 INT292750 Akt1 Positive_regulation of Bcl2 1 0.01 1.67 0.15
91 INT349476 Bax Regulation of Bcl2 1 0.07 1.33 0.15
92 INT266377 Binding of S100a11 and Trp53 1 0.02 0.89 0.15
93 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
94 INT223538 Binding of HAND1 and Tcf3 1 0.39 1.13 0.14
95 INT95104 TGFBR2 Positive_regulation of BCL2 1 0.08 0.61 0.14
96 INT309139 Edc4 Positive_regulation of Bcl2 1 0.03 0.12 0.13
97 INT103557 Binding of ERCC2 and TP53 1 0.40 1 0.13
98 INT148594 Binding of BCL2 and CD34 1 0.39 1.17 0.13
99 INT132148 LTF Positive_regulation of TP53 1 0.44 0.56 0.13
100 INT309142 Edc4 Regulation of Bcl2 1 0.02 0.12 0.13
101 INT246016 Negative_regulation of Timp1 Negative_regulation of Gene_expression of Bcl2 1 0.03 1.07 0.13
102 INT103561 Binding of TP53 and Mc1r 1 0.03 1 0.13
103 INT223530 Binding of Tcf3 and Szf1 1 0.33 0.92 0.13
104 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
105 INT348542 BCL2 Negative_regulation of NLRP1 1 0.07 2.02 0.13
106 INT246017 Timp1 Negative_regulation of Gene_expression of Bcl2 1 0.03 1.07 0.13
107 INT223526 Binding of Pax6 and Tcf3 1 0.33 0.92 0.13
108 INT172899 Binding of Bcl2 and Bcl2l1 3 0.02 5.54 0.12
109 INT178101 EDN1 Negative_regulation of Phosphorylation of BCL2 1 0.03 1 0.12
110 INT305194 Bcl2 Positive_regulation of Epo 1 0.06 0.29 0.12
111 INT83370 Binding of HRAS and TP53 1 0.30 0.59 0.11
112 INT350736 PRKDC Negative_regulation of CA2 1 0.02 0.16 0.11
113 INT273063 Negative_regulation of Fas Negative_regulation of Positive_regulation of Bcl2 1 0.01 0.72 0.11
114 INT350735 PRKDC Negative_regulation of ITPR3 1 0.01 0.16 0.11
115 INT221684 Binding of Bcl2 and FRTS 1 0.01 1.19 0.11
116 INT265888 BCL2 Regulation of Gene_expression of BAD 1 0.04 1.08 0.1
117 INT266386 Binding of S100a1 and Trp53 1 0.03 0.64 0.1
118 INT265890 BCL2 Regulation of Gene_expression of BAX 1 0.04 1.08 0.1
119 INT298267 Tcf3 Positive_regulation of Gene_expression of Runx1 1 0.21 0.6 0.1
120 INT193782 Binding of TP53 and SDF2L1 1 0.00 0.67 0.1
121 INT262522 Binding of Trp53 and Foxo4 1 0.05 0.7 0.1
122 INT310743 TP53 Regulation of BAX 1 0.09 1.11 0.1
123 INT239643 Binding of BCL2 and BCL2L11 3 0.16 2.26 0.09
124 INT282094 Apoa2 Negative_regulation of BCL2 1 0.06 1.15 0.09
125 INT326126 Binding of S100A1 and TP53 1 0.04 1.34 0.09
126 INT275183 Bad Positive_regulation of Gene_expression of Bcl2 1 0.08 0.63 0.09
127 INT265887 IGF1 Negative_regulation of BCL2 1 0.09 1.02 0.09
128 INT294637 Bcl2a1a Positive_regulation of Gene_expression of Bcl2 1 0.15 0.97 0.09
129 INT352611 Trp53 Negative_regulation of Localization of Gli1 1 0.23 1.2 0.09
130 INT302168 YWHAQ Regulation of TP53 1 0.01 0.41 0.09
131 INT204300 Bcl2 Negative_regulation of Positive_regulation of Bak1 1 0.02 1.13 0.09
132 INT265466 CSPG4 Regulation of Phosphorylation of TP53 1 0.09 0.15 0.09
133 INT246625 Sirt1 Positive_regulation of Negative_regulation of Trp53 1 0.10 0.96 0.08
134 INT350908 Binding of Bcl2 and Twist1 1 0.04 1.9 0.08
135 INT266394 Binding of S100a4 and Trp53 1 0.03 0.59 0.08
136 INT201456 Hmox1 Positive_regulation of Gene_expression of Bcl2 1 0.06 0.74 0.08
137 INT266390 Binding of S100a6 and Trp53 1 0.04 0.51 0.07
138 INT204299 Bcl2 Negative_regulation of Localization of Aifm1 1 0.06 1.22 0.07
139 INT223531 Binding of Hmga1 and Tcf3 1 0.26 0.57 0.07
140 INT245296 Trp53 Regulation of Gadd45a 1 0.05 0.43 0.07
141 INT297733 Cbr1 Regulation of Gene_expression of Bcl2 1 0.05 0.94 0.07
142 INT266398 Binding of S100b and Trp53 1 0.06 0.92 0.07
143 INT302143 TP53 Regulation of Positive_regulation of CASP3 1 0.01 0.69 0.06
144 INT302177 PTGER2 Positive_regulation of BCL2 1 0.04 2.08 0.06
145 INT302155 TP53 Regulation of Positive_regulation of CASP9 1 0.02 0.7 0.06
146 INT204074 Tp53 Positive_regulation of Cdkn1b 1 0.00 0.59 0.06
147 INT352299 Regulation of Binding of BCL2 and VIM 1 0.10 1.07 0.06
148 INT140291 ROS1 Positive_regulation of TP53 1 0.52 1.27 0.06
149 INT352298 Binding of BCL2 and VIM 1 0.09 1.06 0.06
150 INT265459 Phosphorylation of TP53 Positive_regulation of Localization of CASP9 1 0.17 1.16 0.05
151 INT352618 Tpt1 Regulation of Trp53 1 0.06 0.54 0.05
152 INT286768 Binding of Trp53 and Tusc2 1 0.07 1.1 0.05
153 INT352621 Gli1 Negative_regulation of Trp53 1 0.32 0.56 0.05
154 INT249201 PRKDC Regulation of Regulation of CYBB 1 0.01 0.09 0.05
155 INT181601 Binding of TP53 and WT1 1 0.30 0.9 0.05
156 INT265454 Phosphorylation of TP53 Positive_regulation of CASP9 1 0.17 1.16 0.05
157 INT341375 Sod2 Regulation of Bcl2 1 0.08 1.96 0.05
158 INT345181 Gpr87 Regulation of Trp53 1 0.01 0.42 0.05
159 INT193788 ITIH4 Regulation of Phosphorylation of TP53 1 0.07 0.45 0.05
160 INT190824 Binding of Cl and Bcl2 1 0.02 1.4 0.05
161 INT287221 Tcf3 Regulation of Transcription of Insig1 1 0.03 0.56 0.05
162 INT352612 Trp53 Negative_regulation of Cd44 1 0.24 1.01 0.04
163 INT352669 PRKDC Positive_regulation of Memor1 1 0.00 1.02 0.04
164 INT333252 Positive_regulation of Binding of Bcl2 and Mcl1 1 0.03 0.88 0.04
165 INT348022 Binding of Jun and Trp53 1 0.07 0.46 0.04
166 INT268664 Ptger2 Positive_regulation of Bcl2 1 0.02 0.9 0.04
167 INT172214 BAX Positive_regulation of TP53 1 0.09 0.37 0.04
168 INT333245 Binding of Bcl2 and Bcl2l11 1 0.03 0.87 0.04
169 INT268666 Ptger2 Positive_regulation of Gene_expression of Bcl2 1 0.02 0.9 0.04
170 INT329230 Negative_regulation of ATIC Positive_regulation of Trp53 1 0.00 0.58 0.04
171 INT329228 ATIC Positive_regulation of Trp53 1 0.01 0.58 0.04
172 INT350905 Binding of Bcl2 and Pcsk4 1 0.03 0.96 0.04
173 INT352619 Bcl2l12 Negative_regulation of Trp53 1 0.27 0.94 0.04
174 INT352613 Binding of Trp53 and Bcl2l12 1 0.23 0.94 0.04
175 INT333253 Binding of Bcl2 and Mcl1 1 0.02 2.14 0.04
176 INT170457 RASGRP1 Regulation of TP53 1 0.02 0.58 0.04
177 INT250025 Map3k1 Positive_regulation of Regulation of Bcl2 1 0.01 1.1 0.04
178 INT201726 Mapk8 Positive_regulation of Positive_regulation of Trp53 1 0.00 0.41 0.04
179 INT172902 Binding of Bax and Bcl2 5 0.30 3.19 0.03
180 INT192164 Binding of BAK1 and BCL2 3 0.04 2.8 0.03
181 INT192167 Negative_regulation of Binding of BAK1 and BCL2 2 0.05 1.89 0.03
182 INT260267 Binding of TFAM and TP53 2 0.37 2.1 0.03
183 INT288538 Il2 Positive_regulation of Gene_expression of Bcl2 1 0.04 1.96 0.03
184 INT355036 CKAP4 Regulation of Positive_regulation of TP53 1 0.08 0.4 0.03
185 INT266903 Binding of Sod2 and Trp53 1 0.05 0 0.03
186 INT211873 TP53 Positive_regulation of Transcription of CD40 1 0.03 1.44 0.03
187 INT234625 TP53 Positive_regulation of IGFBP3 1 0.29 0.74 0.03
188 INT217148 MIR21 Regulation of BCL2 1 0.32 0.98 0.03
189 INT352624 Trp53 Negative_regulation of CEL 1 0.01 1.01 0.03
190 INT101159 Gene_expression of Bcl2 Positive_regulation of Gene_expression of CHAT 1 0.31 0.96 0.03
191 INT265464 CSPG4 Regulation of Gene_expression of TP53 1 0.09 0.23 0.03
192 INT229204 Olr1254 Negative_regulation of Gene_expression of Bcl2 1 0.02 0.18 0.03
193 INT314686 TP53 Regulation of Gene_expression of MDM2 1 0.21 0.96 0.03
194 INT229098 Binding of TP53 and IER3 1 0.01 1.47 0.03
195 INT333259 Bcl2 Regulation of Bax 1 0.03 0.32 0.03
196 INT314677 TP53 Regulation of Positive_regulation of CDKN2A 1 0.27 0.97 0.03
197 INT276389 Binding of Trp53 and KRT20 1 0.01 0.97 0.03
198 INT302134 TP53 Positive_regulation of Transcription of CDKN1A 1 0.04 0.28 0.03
199 INT172894 Negative_regulation of Lox Negative_regulation of Gene_expression of Bcl2 1 0.03 1.12 0.03
200 INT220445 Bcl2 Negative_regulation of Positive_regulation of Casp9 1 0.01 1.37 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported for B cell lineage commitment. They are ordered first by their pain relevance and then by number of times they were reported in B cell lineage commitment. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
2 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
3 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
4 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
5 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
6 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
7 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
8 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
9 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
10 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
11 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
12 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
13 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68
14 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37
15 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27
16 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86
17 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71
18 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
19 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41
20 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
21 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71
22 INT84685 Regulation of BCL2 67 0.60 72.96 6.65
23 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
24 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
25 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7
26 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22
27 INT60585 Regulation of TP53 59 0.59 54.55 5.21
28 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07
29 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
30 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
31 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
32 INT101957 Transcription of Bcl2 30 0.69 16.57 4.3
33 INT105882 Phosphorylation of Bcl2 11 0.59 8.15 3.73
34 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
35 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4
36 INT81642 Regulation of Gene_expression of Bcl2 20 0.44 16.93 3.19
37 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16
38 INT72618 Regulation of Tcf3 5 0.44 1.48 3.16
39 INT105884 Binding of Bcl2 19 0.35 15.67 3
40 INT8103 Binding of TP53 46 0.44 40.2 2.96
41 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
42 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51
43 INT55952 Transcription of TP53 16 0.61 12.14 2.36
44 INT147349 Localization of Bcl2 13 0.65 7.83 2.31
45 INT108148 Positive_regulation of Prkdc 2 0.16 0.49 2.31
46 INT142677 Negative_regulation of Positive_regulation of Bcl2 4 0.36 3.09 2.24
47 INT72616 Negative_regulation of Tcf3 2 0.41 0.97 2.04
48 INT86671 Negative_regulation of Positive_regulation of Bcl2 6 0.57 3.83 2.03
49 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98
50 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
51 INT65855 Localization of TP53 18 0.76 17.08 1.89
52 INT101108 Localization of Bcl2 16 0.72 11.68 1.86
53 INT105883 Positive_regulation of Phosphorylation of Bcl2 8 0.32 5.67 1.86
54 INT113345 Positive_regulation of Phosphorylation of TP53 8 0.66 6.11 1.8
55 INT101958 Positive_regulation of Transcription of Bcl2 4 0.50 2.22 1.65
56 INT137513 Negative_regulation of Positive_regulation of BCL2 6 0.35 5.3 1.62
57 INT64233 Regulation of Trp53 35 0.62 27.11 1.53
58 INT120004 Transcription of Tp53 8 0.72 4.92 1.48
59 INT101990 Negative_regulation of Positive_regulation of TP53 5 0.33 3.69 1.42
60 INT162469 Positive_regulation of Protein_catabolism of TP53 5 0.52 5.48 1.42
61 INT118155 Regulation of Positive_regulation of Prkdc 1 0.10 0.49 1.42
62 INT172953 Binding of Trp53 33 0.37 20.76 1.41
63 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41
64 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41
65 INT145221 Binding of Tp53 10 0.37 8.59 1.37
66 INT101107 Positive_regulation of Localization of Bcl2 3 0.48 3.13 1.28
67 INT125525 Positive_regulation of PRKDC 7 0.45 2.72 1.21
68 INT72614 Negative_regulation of Regulation of Tcf3 1 0.41 0.17 1.2
69 INT174156 Localization of Trp53 16 0.72 13.52 1.18
70 INT116436 Negative_regulation of Phosphorylation of TP53 2 0.40 0.94 1.16
71 INT134661 Negative_regulation of Tp53 11 0.43 10.91 1.13
72 INT172855 Binding of Bcl2 37 0.32 23.41 1.09
73 INT70021 Localization of BCL2 23 0.74 21.6 1.09
74 INT97052 Transcription of Trp53 12 0.64 6.52 1.01
75 INT166935 Gene_expression of Prkdc 10 0.65 3.14 0.9
76 INT151115 Regulation of Regulation of Bcl2 4 0.21 4.12 0.88
77 INT92117 Phosphorylation of BCL2 26 0.80 9.93 0.86
78 INT93356 Negative_regulation of Gene_expression of Trp53 28 0.53 20.61 0.8
79 INT70019 Binding of BCL2 25 0.47 17.55 0.79
80 INT30050 Gene_expression of Tcf3 13 0.48 2.57 0.77
81 INT109404 Transcription of BCL2 6 0.69 4.49 0.77
82 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75
83 INT124844 Regulation of Positive_regulation of Bcl2 3 0.43 2.55 0.75
84 INT168245 Positive_regulation of Transcription of Tp53 2 0.70 2.63 0.75
85 INT125526 Gene_expression of PRKDC 5 0.58 4 0.74
86 INT155392 Negative_regulation of Negative_regulation of Bcl2 3 0.21 1.64 0.74
87 INT162470 Negative_regulation of Protein_catabolism of TP53 1 0.32 1.24 0.74
88 INT134444 Positive_regulation of Binding of Bcl2 3 0.47 2.67 0.72
89 INT93358 Negative_regulation of Positive_regulation of Trp53 9 0.41 3.95 0.6
90 INT53950 Phosphorylation of Tp53 8 0.61 9.4 0.6
91 INT105266 Localization of Tcf3 3 0.32 1.08 0.59
92 INT70025 Positive_regulation of Positive_regulation of BCL2 3 0.27 0.96 0.58
93 INT178128 Negative_regulation of Phosphorylation of BCL2 7 0.27 3.94 0.56
94 INT155090 Regulation of Positive_regulation of BCL2 3 0.26 1.78 0.54
95 INT144696 Regulation of Transcription of Bcl2 5 0.44 2.96 0.51
96 INT286035 Negative_regulation of Gene_expression of Tp53 5 0.32 6.2 0.49
97 INT134445 Positive_regulation of Positive_regulation of Bcl2 3 0.47 2.43 0.49
98 INT221676 Protein_catabolism of Bcl2 4 0.24 2.77 0.48
99 INT204052 Transcription of Bcl2 5 0.51 3.25 0.45
100 INT140295 Protein_catabolism of BCL2 4 0.64 5.7 0.44
101 INT220424 Positive_regulation of Negative_regulation of Bcl2 2 0.14 1.81 0.44
102 INT139976 Regulation of Tp53 7 0.44 6.49 0.39
103 INT155724 Negative_regulation of Transcription of Bcl2 6 0.53 2.35 0.37
104 INT30052 Positive_regulation of Tcf3 3 0.41 0.27 0.37
105 INT145220 Negative_regulation of Binding of Tp53 1 0.20 0.75 0.36
106 INT93355 Negative_regulation of Negative_regulation of Trp53 2 0.41 0.92 0.3
107 INT179089 Protein_catabolism of Trp53 8 0.90 6.52 0.29
108 INT125524 Positive_regulation of Gene_expression of PRKDC 2 0.09 1 0.29
109 INT178114 Positive_regulation of Phosphorylation of BCL2 11 0.49 4.44 0.28
110 INT180393 Positive_regulation of Gene_expression of Prkdc 3 0.49 1.17 0.26
111 INT166960 Positive_regulation of Negative_regulation of TP53 2 0.25 1.65 0.26
112 INT314729 Regulation of Localization of TP53 1 0.30 2.5 0.25
113 INT292743 Negative_regulation of Binding of Bcl2 1 0.05 1.97 0.24
114 INT179088 Positive_regulation of Regulation of Trp53 3 0.38 3.23 0.23
115 INT156886 Positive_regulation of Localization of TP53 1 0.48 0.87 0.23
116 INT285003 Positive_regulation of Regulation of Bcl2 1 0.46 0.68 0.23
117 INT327888 Localization of Prkdc 1 0.14 1.11 0.23
118 INT108563 Negative_regulation of Regulation of Bcl2 1 0.32 0.74 0.22
119 INT220426 Regulation of Negative_regulation of Bcl2 1 0.05 0.81 0.18
120 INT300284 Regulation of Phosphorylation of Tp53 1 0.16 1.51 0.17
121 INT337078 Negative_regulation of Localization of Trp53 1 0.20 1.3 0.17
122 INT238507 Regulation of Regulation of BCL2 3 0.44 5.14 0.16
123 INT101109 Negative_regulation of Localization of Bcl2 1 0.03 0.62 0.16
124 INT179086 Positive_regulation of Negative_regulation of Trp53 5 0.50 4.78 0.15
125 INT229235 Regulation of Localization of BCL2 2 0.29 3.7 0.15
126 INT125081 Positive_regulation of Binding of TP53 2 0.46 1.2 0.15
127 INT207805 Negative_regulation of Phosphorylation of Trp53 2 0.18 0.98 0.15
128 INT102109 Protein_catabolism of Bcl2 1 0.65 0.55 0.15
129 INT286749 Regulation of Localization of Trp53 1 0.06 1.39 0.15
130 INT110957 Positive_regulation of Positive_regulation of Bcl2 3 0.35 2.3 0.13
131 INT90229 Transcription of Tcf3 2 0.12 0.39 0.13
132 INT168244 Regulation of Transcription of Tp53 1 0.33 0.57 0.13
133 INT290726 Binding of Prkdc 1 0.03 1.05 0.13
134 INT179038 Positive_regulation of Regulation of Bcl2 1 0.39 3.49 0.12
135 INT297456 Protein_catabolism of Tp53 1 0.11 0.72 0.1
136 INT111139 Localization of Tp53 4 0.45 2.4 0.09
137 INT352666 Regulation of PRKDC 1 0.01 0.36 0.09
138 INT249260 Positive_regulation of Phosphorylation of PRKDC 1 0.03 0.06 0.08
139 INT249280 Phosphorylation of PRKDC 2 0.13 0.3 0.07
140 INT352605 Regulation of Negative_regulation of Trp53 1 0.45 0.72 0.07
141 INT171421 Regulation of Positive_regulation of TP53 1 0.48 0.45 0.05
142 INT315213 Negative_regulation of Binding of Trp53 1 0.32 0.11 0.05
143 INT302229 Negative_regulation of Negative_regulation of BCL2 3 0.21 2.69 0.04
144 INT311668 Regulation of Regulation of TP53 2 0.36 3.58 0.04
145 INT295091 Positive_regulation of Gene_expression of Tcf3 2 0.19 0.4 0.04
146 INT305536 Positive_regulation of Binding of Trp53 1 0.35 0.32 0.04
147 INT217802 Regulation of Transcription of TP53 2 0.37 0.81 0.03
148 INT258045 Positive_regulation of Regulation of BCL2 2 0.36 1.78 0.03
149 INT259061 Negative_regulation of Regulation of TP53 2 0.10 2.23 0.03
150 INT221673 Negative_regulation of Protein_catabolism of Bcl2 1 0.11 0.15 0.03
151 INT352653 Positive_regulation of Positive_regulation of PRKDC 1 0.01 0.56 0.03
152 INT123521 Phosphorylation of Bcl2 8 0.81 5 0
153 INT178927 Regulation of Gene_expression of Tp53 6 0.26 2.23 0
154 INT333669 Positive_regulation of Transcription of Trp53 3 0.45 2.33 0
155 INT310419 Negative_regulation of Localization of BCL2 3 0.41 2.51 0
156 INT185909 Regulation of Phosphorylation of BCL2 3 0.24 1.63 0
157 INT250698 Positive_regulation of Transcription of TP53 3 0.18 3.68 0
158 INT155391 Positive_regulation of Negative_regulation of Bcl2 2 0.22 0.92 0
159 INT185887 Regulation of Binding of BCL2 2 0.24 2.22 0
160 INT180394 Phosphorylation of Prkdc 2 0.07 0.6 0
161 INT113348 Negative_regulation of Binding of TP53 2 0.28 1.49 0
162 INT183619 Negative_regulation of Regulation of BCL2 2 0.33 1.01 0
163 INT191056 Negative_regulation of Binding of Bcl2 2 0.37 0.48 0
164 INT214913 Positive_regulation of Positive_regulation of Tp53 2 0.08 2.47 0
165 INT217820 Regulation of Negative_regulation of TP53 2 0.37 1.92 0
166 INT153083 Positive_regulation of Negative_regulation of BCL2 2 0.32 2.9 0
167 INT204059 Positive_regulation of Phosphorylation of Tp53 1 0.07 0.76 0
168 INT295084 Regulation of Gene_expression of Tcf3 1 0.20 0.36 0
169 INT333668 Regulation of Protein_catabolism of Trp53 1 0.24 1.58 0
170 INT352658 Negative_regulation of PRKDC 1 0.01 0.33 0
171 INT204053 Negative_regulation of Transcription of Bcl2 1 0.04 0.86 0
172 INT330962 Negative_regulation of Transcription of BCL2 1 0.10 1.21 0
173 INT333671 Regulation of Transcription of Trp53 1 0.24 0.83 0
174 INT179076 Negative_regulation of Protein_catabolism of Trp53 1 0.32 0.43 0
175 INT282976 Positive_regulation of Binding of Bcl2 1 0.29 0.76 0
176 INT179957 Positive_regulation of Binding of Tp53 1 0.08 0.48 0
177 INT191048 Positive_regulation of Phosphorylation of Bcl2 1 0.69 0.44 0
178 INT333663 Positive_regulation of Protein_catabolism of Trp53 1 0.45 0.84 0
179 INT341935 Regulation of Phosphorylation of Bcl2 1 0.04 0 0
180 INT333662 Negative_regulation of Transcription of Trp53 1 0.53 1.15 0
181 INT282971 Positive_regulation of Localization of Bcl2 1 0.29 0 0
182 INT356124 Positive_regulation of Transcription of BCL2 1 0.45 0.3 0
183 INT223765 Negative_regulation of Positive_regulation of Tp53 1 0.07 1.69 0
184 INT191049 Regulation of Binding of Bcl2 1 0.39 0.52 0
185 INT184508 Positive_regulation of Localization of BCL2 1 0.07 0.87 0
186 INT305295 Regulation of Binding of TP53 1 0.39 1.09 0
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