GO:0002554

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Name serotonin secretion by platelet
Categary Process
Go Slim No
Go Link GO:0002554
Unique Molecular Interactions 44
Total Molecular Interactions 54
Total Single Events 702
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for serotonin secretion by platelet. They are ordered first by their pain relevance and then by number of times they were reported for serotonin secretion by platelet. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT160653 Binding of P2rx1 and Ptgfr 1 0.28 0.66 1.14
2 INT215584 P2rx1 Regulation of Localization of Gabrg1 1 0.01 0 0.92
3 INT102350 P2rx1 Negative_regulation of Localization of Il6 1 0.32 0 0.67
4 INT151783 Regulation of Binding of Calca and P2rx1 1 0.42 0.51 0.64
5 INT151778 Binding of Calca and P2rx1 1 0.35 0.5 0.64
6 INT152281 Binding of P2rx1 and Trpv1 1 0.15 0.42 0.49
7 INT151782 Phosphorylation of Creb1 Positive_regulation of Gene_expression of P2rx1 1 0.41 0.07 0.44
8 INT151781 Calca Positive_regulation of Gene_expression of P2rx1 1 0.50 0.07 0.44
9 INT217034 P2RX1 Regulation of Gene_expression of Ik 1 0.00 0.34 0.42
10 INT196883 Prkca Regulation of P2rx1 1 0.05 0.45 0.31
11 INT258857 Binding of P2rx1 and P2ry2 1 0.22 0.81 0.29
12 INT302818 Gcat Negative_regulation of Syk 1 0.00 0.53 0.24
13 INT264277 Binding of Car2 and P2rx1 1 0.10 0 0.16
14 INT264276 Binding of Ednrb and P2rx1 1 0.00 0.17 0.16
15 INT278373 Myd88 Regulation of Phosphorylation of Syk 1 0.15 0.35 0.15
16 INT336665 Binding of P2rx1 and P2rx2 1 0.07 0 0.14
17 INT275451 Binding of ZAP70 and Syk 1 0.02 0.12 0.1
18 INT275450 Binding of STAM and Syk 1 0.00 0.12 0.1
19 INT313486 GOPC Positive_regulation of P2RX1 1 0.13 0 0.1
20 INT313484 Binding of P2RX1 and SST 1 0.04 0 0.09
21 INT304456 Binding of P2rx1 and P2rx4 1 0.14 0 0.07
22 INT267093 FGFR1 Positive_regulation of Gene_expression of P2rx1 1 0.03 0.2 0.03
23 INT313485 MTOR Positive_regulation of Gene_expression of P2RX1 1 0.16 0 0.03
24 INT278404 Syk Positive_regulation of Mapk1 1 0.13 0 0
25 INT224024 Binding of P2RX1 and WDTC1 1 0.01 0.71 0
26 INT278400 Negative_regulation of Syk Negative_regulation of Positive_regulation of Hps5 1 0.16 0 0
27 INT278382 Binding of Syk and Nlrp3 1 0.24 0 0
28 INT339800 P2RX1 Regulation of Negative_regulation of GOPC 1 0.04 0 0
29 INT278401 Syk Regulation of Positive_regulation of Hps5 1 0.19 0 0
30 INT278410 Gopc Positive_regulation of Phosphorylation of Syk 1 0.10 0.23 0
31 INT224027 Binding of P2RX1 and P2RY12 1 0.10 0.71 0
32 INT278387 Syk Regulation of Positive_regulation of Il1 1 0.06 0 0
33 INT278372 Binding of Syk and Pycard 1 0.06 0 0
34 INT278399 Syk Positive_regulation of Localization of Ctsb 1 0.09 0.28 0
35 INT278405 Tlr4 Positive_regulation of Syk 1 0.06 0 0
36 INT209444 Stam Positive_regulation of Syk 1 0.01 0.26 0
37 INT278392 Syk Regulation of Positive_regulation of Ctsb 1 0.06 0 0
38 INT278396 Msu Positive_regulation of Phosphorylation of Syk 1 0.25 0.27 0
39 INT154173 Binding of SIPA1 and SYK 1 0.16 0.46 0
40 INT278380 Syk Positive_regulation of Pik3r1 1 0.13 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for serotonin secretion by platelet. They are ordered first by their pain relevance and then by number of times they were reported in serotonin secretion by platelet. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT64436 Gene_expression of P2rx1 93 0.78 32.69 36.12
2 INT70776 Positive_regulation of P2rx1 62 0.62 32.55 30.75
3 INT90942 Regulation of P2rx1 31 0.61 16.61 13.69
4 INT70775 Positive_regulation of Positive_regulation of P2rx1 15 0.49 8.65 8.49
5 INT95172 Localization of P2rx1 14 0.78 6.77 7.81
6 INT90943 Negative_regulation of P2rx1 13 0.42 8.21 7.22
7 INT114014 Positive_regulation of Gene_expression of P2rx1 13 0.69 7.77 7.15
8 INT91351 Gene_expression of P2rx1 28 0.75 5.89 6.78
9 INT71758 Gene_expression of P2RX1 40 0.75 9.01 6.14
10 INT71759 Positive_regulation of P2RX1 13 0.67 3.53 4.9
11 INT144396 Positive_regulation of P2rx1 11 0.49 3.25 4.23
12 INT95171 Binding of P2rx1 12 0.36 4.69 3.92
13 INT26833 Negative_regulation of P2rx1 9 0.41 1.5 2.89
14 INT121435 Negative_regulation of Gene_expression of P2rx1 3 0.43 1.82 2.21
15 INT278340 Gene_expression of Syk 7 0.51 4.92 2.09
16 INT215166 Binding of P2rx1 5 0.35 0.41 1.97
17 INT106984 Regulation of P2RX1 12 0.60 2.05 1.75
18 INT146948 Negative_regulation of Positive_regulation of P2rx1 2 0.34 2.23 1.74
19 INT149435 Regulation of Positive_regulation of P2rx1 2 0.30 1.55 1.67
20 INT151777 Regulation of Gene_expression of P2rx1 3 0.60 1.97 1.48
21 INT215162 Phosphorylation of P2rx1 2 0.43 0.12 1.34
22 INT155662 Positive_regulation of Localization of P2rx1 2 0.47 1.92 1.26
23 INT71757 Localization of P2RX1 4 0.73 2.11 1.22
24 INT132283 Regulation of P2rx1 3 0.13 0 1.2
25 INT160652 Positive_regulation of Binding of P2rx1 1 0.36 0.67 1.15
26 INT107143 Negative_regulation of P2RX1 11 0.56 2.92 1.01
27 INT267071 Positive_regulation of Gene_expression of P2rx1 2 0.49 1.77 0.98
28 INT275940 Negative_regulation of Syk 3 0.39 2.08 0.95
29 INT127103 Negative_regulation of Gene_expression of P2rx1 5 0.41 0.46 0.91
30 INT192123 Transcription of P2rx1 4 0.27 1.24 0.91
31 INT148118 Positive_regulation of Gene_expression of P2RX1 4 0.48 0.78 0.83
32 INT126572 Positive_regulation of SYK 3 0.67 2.98 0.83
33 INT108044 Phosphorylation of Syk 3 0.25 1.39 0.77
34 INT224011 Binding of P2RX1 7 0.45 1.12 0.6
35 INT132324 Localization of SYK 2 0.78 1.9 0.59
36 INT278152 Negative_regulation of Syk 1 0.24 1.93 0.59
37 INT217018 Regulation of Regulation of P2RX1 3 0.26 0.34 0.54
38 INT215787 Localization of P2rx1 3 0.68 0.49 0.54
39 INT132325 Positive_regulation of Localization of SYK 1 0.49 0.56 0.54
40 INT154180 Negative_regulation of SYK 3 0.43 4.67 0.5
41 INT302775 Negative_regulation of Gene_expression of Syk 1 0.27 0.84 0.48
42 INT313494 Regulation of Gene_expression of P2RX1 3 0.42 0 0.45
43 INT154182 Phosphorylation of SYK 6 0.82 5.54 0.43
44 INT215494 Positive_regulation of Phosphorylation of P2rx1 1 0.26 0 0.42
45 INT217012 Transcription of P2RX1 1 0.21 0.26 0.39
46 INT239115 Regulation of Binding of P2rx1 1 0.16 0 0.39
47 INT215503 Negative_regulation of Positive_regulation of P2rx1 1 0.23 0 0.38
48 INT154181 Positive_regulation of Phosphorylation of SYK 4 0.70 4.71 0.37
49 INT341920 Negative_regulation of Binding of P2rx1 1 0.20 0.06 0.36
50 INT154175 Regulation of SYK 2 0.62 1.48 0.34
51 INT108043 Negative_regulation of Phosphorylation of Syk 1 0.13 0.53 0.31
52 INT154559 Positive_regulation of Syk 2 0.20 0.74 0.3
53 INT278155 Regulation of Negative_regulation of Syk 1 0.18 0.55 0.26
54 INT252723 Gene_expression of SYK 3 0.25 2.67 0.23
55 INT278154 Regulation of Syk 1 0.05 0.98 0.22
56 INT278147 Localization of Syk 1 0.30 0.98 0.22
57 INT224005 Negative_regulation of Gene_expression of P2RX1 3 0.40 0.48 0.17
58 INT275937 Phosphorylation of Syk 3 0.54 1.67 0.15
59 INT154177 Negative_regulation of Phosphorylation of SYK 1 0.43 1.51 0.14
60 INT341919 Positive_regulation of Binding of P2rx1 1 0.23 0 0.11
61 INT275411 Binding of Syk 1 0.09 0.12 0.1
62 INT339811 Regulation of Positive_regulation of P2RX1 1 0.42 0 0.08
63 INT199076 Positive_regulation of Syk 3 0.31 0.12 0.07
64 INT215817 Transcription of P2rx1 1 0.18 0 0.04
65 INT278363 Binding of Syk 1 0.32 0.3 0.04
66 INT276348 Positive_regulation of Positive_regulation of SYK 1 0.22 0.66 0.04
67 INT313493 Positive_regulation of Negative_regulation of P2RX1 1 0.48 0 0.04
68 INT276371 Positive_regulation of Gene_expression of SYK 1 0.22 0.67 0.03
69 INT154178 Binding of SYK 1 0.37 0.46 0
70 INT278354 Positive_regulation of Phosphorylation of Syk 1 0.31 0.23 0
71 INT275951 Negative_regulation of Phosphorylation of Syk 1 0.34 0.2 0
72 INT278348 Positive_regulation of Gene_expression of Syk 1 0.33 0 0
73 INT278326 Regulation of Positive_regulation of Syk 1 0.18 0 0
74 INT194939 Regulation of Phosphorylation of SYK 1 0.18 0.31 0
75 INT278346 Positive_regulation of Negative_regulation of Syk 1 0.33 0 0
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