GO:0003308

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Name negative regulation of Wnt receptor signaling pathway involved in heart development
Categary Process
Go Slim No
Go Link GO:0003308
Unique Molecular Interactions 41
Total Molecular Interactions 81
Total Single Events 207
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of Wnt receptor signaling pathway involved in heart development. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of Wnt receptor signaling pathway involved in heart development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT234992 Car2 Positive_regulation of Jup 1 0.02 0.27 0.2
2 INT201762 JUP Regulation of Gene_expression of Ccnd1 1 0.03 0.8 0.13
3 INT201791 JUP Regulation of Gene_expression of Myc 1 0.49 0.8 0.13
4 INT339111 Binding of ERBB2 and JUP 1 0.38 0.62 0.07
5 INT339108 Binding of ESR1 and JUP 1 0.38 0.62 0.07
6 INT349914 Binding of Cdh1 and Jup 1 0.11 0.47 0.07
7 INT234968 IgG Negative_regulation of Jup 1 0.02 1.09 0.06
8 INT192044 Binding of DSP and Jup 2 0.24 2.39 0
9 INT234995 Binding of CDH16 and Jup 1 0.00 0.27 0
10 INT269943 Sox17 Regulation of Binding of Smad3 1 0.37 0.12 0
11 INT269915 Binding of Smad2 and Sox17 1 0.21 0.07 0
12 INT269919 Sox17 Negative_regulation of Binding of Smad3 1 0.36 0 0
13 INT234969 Jup Regulation of Gene_expression of Dsp 1 0.01 0.54 0
14 INT269948 Sox17 Positive_regulation of Gene_expression of Ccnd1 1 0.61 0.19 0
15 INT235007 Binding of DSG1 and Jup 1 0.08 0.36 0
16 INT235005 Positive_regulation of Binding of DSG1 and Jup 1 0.08 0.36 0
17 INT269940 Binding of Sox17 and Scn4a 1 0.17 0.15 0
18 INT234983 IgG Positive_regulation of Protein_catabolism of Jup 1 0.03 0.61 0
19 INT269955 Positive_regulation of Binding of Smad3 and Sox17 1 0.39 0.05 0
20 INT269928 Binding of Sox17 and Mgst1 1 0.12 0 0
21 INT192045 Jup Positive_regulation of RYR2 1 0.11 0.29 0
22 INT269949 Sox17 Positive_regulation of Ccnd1 1 0.61 0.96 0
23 INT269954 Sox17 Regulation of Gene_expression of Foxa2 1 0.43 0 0
24 INT234970 Binding of Jup and Lat 1 0.01 0 0
25 INT269950 Sox17 Negative_regulation of Gene_expression of Cdkn2b 1 0.27 0.24 0
26 INT266555 Mapk8 Regulation of JUP 1 0.08 0.1 0
27 INT269947 Sox17 Positive_regulation of Gene_expression of Atxn1 1 0.08 0 0
28 INT269957 Sox17 Negative_regulation of Gene_expression of TGFB1 1 0.04 0 0
29 INT269941 Sox17 Regulation of Gene_expression of Foxa1 1 0.56 0 0
30 INT269942 Sox17 Regulation of Smad3 1 0.37 0.12 0
31 INT269934 Sox17 Regulation of Gopc 1 0.12 0 0
32 INT234987 Binding of Jup and Dsp 1 0.01 0.18 0
33 INT269951 Binding of Sox17 and Gopc 1 0.11 0 0
34 INT269930 Binding of Smad3 and Sox17 1 0.40 1.16 0
35 INT269945 Sox17 Positive_regulation of Localization of Ccnd1 1 0.39 0 0
36 INT269922 Sox17 Regulation of Ccnd1 1 0.47 0 0
37 INT269931 Binding of Ccnd1 and Sox17 1 0.33 0.19 0
38 INT269918 Binding of Scn5a and Sox17 1 0.18 0.15 0
39 INT269916 Sox17 Positive_regulation of Pcna 1 0.16 0 0
40 INT192042 Binding of Jup and Ryr2 1 0.17 1.09 0
41 INT234982 Binding of Jup and Pkp1 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of Wnt receptor signaling pathway involved in heart development. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of Wnt receptor signaling pathway involved in heart development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT242171 Protein_catabolism of JUP 4 0.96 0.91 1.01
2 INT266535 Phosphorylation of JUP 3 0.79 0.63 0.49
3 INT242168 Transcription of JUP 4 0.67 1.17 0.46
4 INT242169 Positive_regulation of Protein_catabolism of JUP 1 0.49 0.23 0.34
5 INT185886 Gene_expression of JUP 20 0.75 15.41 0.32
6 INT221860 Negative_regulation of Jup 9 0.15 6.82 0.26
7 INT234903 Gene_expression of Jup 1 0.23 7.1 0.2
8 INT205083 Positive_regulation of JUP 6 0.49 5.51 0.13
9 INT242173 Positive_regulation of Gene_expression of JUP 2 0.49 2.37 0.09
10 INT309877 Localization of JUP 2 0.73 1.38 0.08
11 INT339206 Negative_regulation of Localization of JUP 1 0.41 1.1 0.08
12 INT234894 Negative_regulation of Protein_catabolism of Jup 1 0.17 2.87 0.08
13 INT234866 Regulation of Jup 2 0.08 0.58 0.06
14 INT234899 Positive_regulation of Protein_catabolism of Jup 1 0.21 0.88 0.06
15 INT329585 Regulation of Negative_regulation of Jup 1 0.01 0.23 0.06
16 INT234931 Protein_catabolism of Jup 1 0.29 2.23 0.06
17 INT234915 Positive_regulation of Gene_expression of Jup 1 0.15 2.7 0.06
18 INT234890 Phosphorylation of Jup 1 0.24 1.56 0.03
19 INT234867 Localization of Jup 1 0.24 2.84 0.03
20 INT266537 Positive_regulation of Phosphorylation of JUP 2 0.49 0.29 0
21 INT266534 Negative_regulation of Phosphorylation of JUP 2 0.41 0.15 0
22 INT242174 Negative_regulation of Gene_expression of JUP 2 0.41 2.58 0
23 INT221864 Binding of JUP 2 0.36 1.05 0
24 INT221859 Binding of Jup 2 0.14 2.21 0
25 INT200864 Positive_regulation of Sox17 2 0.50 0.07 0
26 INT269903 Localization of Sox17 1 0.75 0.07 0
27 INT309874 Positive_regulation of Binding of JUP 1 0.49 0.32 0
28 INT269907 Positive_regulation of Localization of Sox17 1 0.50 0.2 0
29 INT269904 Regulation of Sox17 1 0.45 0 0
30 INT234877 Positive_regulation of Binding of Jup 1 0.21 0.24 0
31 INT242170 Negative_regulation of JUP 1 0.42 0.85 0
32 INT269876 Binding of Sox17 1 0.48 0.72 0
33 INT269885 Negative_regulation of Sox17 1 0.42 0.32 0
34 INT269891 Positive_regulation of Gene_expression of Sox17 1 0.69 0.4 0
35 INT269878 Negative_regulation of Gene_expression of Sox17 1 0.42 0 0
36 INT269892 Transcription of Sox17 1 0.71 0 0
37 INT309876 Regulation of JUP 1 0.60 0.67 0
38 INT234918 Positive_regulation of Jup 1 0.15 1.08 0
39 INT309875 Regulation of Gene_expression of JUP 1 0.44 0.39 0
40 INT269898 Positive_regulation of Binding of Sox17 1 0.44 0 0
41 INT269869 Gene_expression of Sox17 1 0.77 2.48 0
42 INT234896 Negative_regulation of Gene_expression of Jup 1 0.13 0.54 0
43 INT269882 Regulation of Gene_expression of Sox17 1 0.61 0.14 0
44 INT355092 Positive_regulation of Transcription of JUP 1 0.49 0.05 0
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