GO:0003746

Name translation elongation factor activity Categary Function Go Slim No Go Link GO:0003746

Unique Molecular Interactions 66 Total Molecular Interactions 71 Total Single Events 885 Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for translation elongation factor activity. They are ordered first by their pain relevance and then by number of times they were reported for translation elongation factor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT227493	Binding of TCEA1 and SIRT2	1	0.01	1.55	1.93
2	INT224856	Binding of Bdnf and Eef2	1	0.14	0	1.02
3	INT43647	Binding of Eef1a1 and Man2a2	1	0.16	0.23	0.7
4	INT36511	Binding of Htr2a and Eef1a1	1	0.22	0	0.62
5	INT41250	Binding of Adra2a and Eef1a1	1	0.06	0.4	0.56
6	INT182813	EEF1A2 Negative_regulation of ITGAL	1	0.10	1.53	0.51
7	INT72525	Positive_regulation of TCEA1 Positive_regulation of Pomc	1	0.08	0	0.5
8	INT72524	Positive_regulation of TCEA1 Positive_regulation of Localization of Pomc	1	0.08	0	0.48
9	INT338086	PYCARD Positive_regulation of TCEA1	1	0.10	0	0.47
10	INT227495	Regulation of Binding of TCEA1 and SIRT2	1	0.01	0.45	0.45
11	INT56578	Eef1a1 Positive_regulation of Localization of Gnrh1	1	0.16	0	0.43
12	INT40208	Binding of Eef1a1 and Hils1	1	0.01	0.22	0.42
13	INT114516	Eef1a1 Positive_regulation of Transcription of co	1	0.00	0	0.41
14	INT207110	Adam3 Regulation of Gene_expression of Eef1a1	1	0.01	1	0.41
15	INT182817	EEF1A2 Positive_regulation of BMP2	1	0.26	1.62	0.28
16	INT239335	Eef1a2 Positive_regulation of Ppara	1	0.27	0.57	0.26
17	INT40964	Binding of Eef1a1 and Positive_regulation of Localization of Acot1	1	0.08	0	0.26
18	INT40854	Man2a2 Regulation of Regulation of Eef1a1	1	0.03	0	0.25
19	INT246576	EEF1A2 Negative_regulation of Negative_regulation of NOSTRIN	1	0.04	0.63	0.24
20	INT144588	Binding of EEF1A2 and pad	1	0.36	1.34	0.24
21	INT182816	EEF1A2 Negative_regulation of CRP	1	0.28	1.84	0.21
22	INT302731	Binding of Gfm1 and Hk	1	0.01	1	0.2
23	INT302732	Positive_regulation of Binding of Gfm1 and Hk	1	0.01	1	0.2
24	INT47842	Man2a2 Regulation of Eef1a1	1	0.01	0	0.18
25	INT230455	FOXG1 Negative_regulation of HBS1L	1	0.02	1.73	0.18
26	INT173499	EEF1A2 Negative_regulation of Cpox	1	0.07	0.39	0.14
27	INT173498	EEF1A2 Regulation of Cpox	1	0.04	0.39	0.14
28	INT317893	Binding of Eef1a1 and Mmp9	1	0.02	1.04	0.11
29	INT317888	Binding of Eef1a1 and Pik3r1	1	0.01	1.04	0.11
30	INT317898	Binding of Akt1 and Eef1a1	1	0.01	1.04	0.11
31	INT227137	Binding of HBS1L and BDNF-AS	1	0.00	1.32	0.08
32	INT212922	Binding of Car2 and Gfm1	1	0.02	0.19	0.06
33	INT239320	Eef1a2 Negative_regulation of Hmgcr	1	0.06	0.89	0.04
34	INT322671	Binding of Gfm1 and Pbrm1	1	0.00	0.96	0.04
35	INT206685	IMPA1 Positive_regulation of HBS1L	1	0.00	0.24	0.04
36	INT254908	ARSH Regulation of Eef1a1	1	0.00	0.89	0.04
37	INT351915	P2ry1 Regulation of Gfm1	1	0.01	0.86	0.03
38	INT351914	P2ry1 Regulation of Gene_expression of Gfm1	1	0.01	0.86	0.03
39	INT298872	RAB7A Regulation of Protein_catabolism of GFM1	1	0.47	0.22	0.03
40	INT317318	Binding of Gfm1 and Trap1	1	0.01	0.83	0
41	INT317317	Binding of Psmb10 and Gfm1	1	0.00	0.73	0
42	INT239325	Eef1a2 Negative_regulation of Lipc	1	0.11	0.84	0
43	INT217788	MIR181A1 Regulation of EIF5A	1	0.23	0.69	0
44	INT342731	Pink1 Regulation of Localization of Gfm1	1	0.00	0.61	0
45	INT311384	Binding of Cnbp and Eef2	1	0.07	0.15	0
46	INT338179	EEF1D Regulation of CDCP1	1	0.00	1.43	0
47	INT311393	Binding of Eef2 and Rps17	1	0.02	0.15	0
48	INT302596	Eef1a2 Negative_regulation of LDLR	1	0.14	0.31	0
49	INT182818	EEF1A2 Negative_regulation of STAR	1	0.01	1.48	0
50	INT221233	Positive_regulation of Binding of Gja3 and Gfm1	1	0.00	0	0
51	INT239350	Eef1a2 Positive_regulation of Apoa1	1	0.22	0.86	0
52	INT221239	Binding of Gja3 and Gfm1	1	0.00	0	0
53	INT260727	Binding of Gfm1 and NAFLD2	1	0.00	1.05	0
54	INT260726	Positive_regulation of Binding of Gfm1 and NAFLD2	1	0.00	1.05	0
55	INT311377	Binding of Eef2 and Pabpc1	1	0.01	0.15	0
56	INT317314	Gfm1 Positive_regulation of Gene_expression of Ros1	1	0.00	0.61	0

Single Events

The table below shows the top 100 pain related interactions that have been reported for translation elongation factor activity. They are ordered first by their pain relevance and then by number of times they were reported in translation elongation factor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT48642	Positive_regulation of TCEA1	92	0.70	24.59	53.64
2	INT7531	Positive_regulation of Eef1a1	29	0.62	8.16	15.41
3	INT16659	Gene_expression of Eef1a1	34	0.64	6.1	11.85
4	INT6384	Regulation of Eef1a1	21	0.61	2.95	7.97
5	INT72523	Regulation of TCEA1	18	0.45	3.19	7.6
6	INT18578	Binding of Eef1a1	20	0.48	2.53	6.95
7	INT42132	Negative_regulation of TCEA1	13	0.51	4.12	6.28
8	INT42133	Gene_expression of TCEA1	17	0.60	5.61	5.55
9	INT18577	Negative_regulation of Eef1a1	20	0.39	3.57	5.24
10	INT52203	Negative_regulation of Positive_regulation of TCEA1	5	0.51	3.27	4.48
11	INT48643	Regulation of Positive_regulation of TCEA1	6	0.53	1.94	3.83
12	INT181249	Binding of TCEA1	8	0.32	2.12	3.66
13	INT139010	Regulation of Gfm1	16	0.32	5.02	3.27
14	INT137679	Localization of Gfm1	18	0.08	9.58	3.24
15	INT19393	Gene_expression of Gfm1	31	0.51	18.9	3.2
16	INT136784	Phosphorylation of Eef2	4	0.55	0	2.79
17	INT181250	Localization of TCEA1	6	0.75	1.54	2.61
18	INT75813	Positive_regulation of Positive_regulation of TCEA1	1	0.50	1.28	2.49
19	INT139008	Positive_regulation of Gfm1	21	0.35	7.79	2.34
20	INT71268	Positive_regulation of Gene_expression of Eef1a1	7	0.41	1.75	2.26
21	INT71266	Regulation of Gene_expression of Eef1a1	1	0.51	0	2.2
22	INT6628	Transcription of Eef1a1	4	0.16	2.59	1.8
23	INT136782	Positive_regulation of Phosphorylation of Eef2	1	0.41	0	1.78
24	INT32939	Positive_regulation of Positive_regulation of Eef1a1	2	0.19	0	1.67
25	INT136786	Regulation of Eef2	3	0.61	0	1.64
26	INT94827	Gene_expression of HBS1L	24	0.67	26.11	1.61
27	INT113785	Negative_regulation of Eef1a2	15	0.31	1.33	1.48
28	INT18493	Localization of Eef1a1	4	0.70	0.18	1.45
29	INT117148	Gene_expression of Eef1a1	6	0.07	2.32	1.42
30	INT15990	Binding of Gfm1	10	0.31	8.53	1.37
31	INT41893	Negative_regulation of HBS1L	16	0.23	8.98	1.19
32	INT158831	Phosphorylation of Gfm1	10	0.58	5.99	1.19
33	INT136787	Regulation of Regulation of Eef2	1	0.45	0	1.18
34	INT25451	Negative_regulation of Gfm1	13	0.27	8.22	1.06
35	INT158833	Regulation of Gene_expression of Gfm1	3	0.32	1.34	1.04
36	INT114830	Positive_regulation of Regulation of TCEA1	2	0.41	0.11	0.94
37	INT158832	Regulation of Phosphorylation of Gfm1	2	0.32	0.61	0.9
38	INT210762	Positive_regulation of Eef1a1	3	0.07	1.91	0.89
39	INT149641	Binding of Eef1a1	3	0.02	1.72	0.87
40	INT49846	Localization of HBS1L	4	0.24	1.31	0.86
41	INT147488	Gene_expression of Eef1a2	5	0.49	0.87	0.84
42	INT157293	Gene_expression of EEF1A2	4	0.78	4.07	0.77
43	INT46711	Negative_regulation of Binding of Eef1a1	1	0.28	0	0.76
44	INT37431	Binding of Eef1a2	1	0.17	0	0.75
45	INT40084	Binding of HBS1L	8	0.36	9.15	0.69
46	INT94826	Positive_regulation of HBS1L	13	0.40	4.62	0.61
47	INT71264	Negative_regulation of Gene_expression of Eef1a1	1	0.48	0	0.58
48	INT136781	Positive_regulation of Eef2	1	0.22	0	0.56
49	INT152525	Negative_regulation of Eef1a1	1	0.07	0.91	0.55
50	INT33574	Negative_regulation of Positive_regulation of Eef1a1	1	0.04	0.18	0.53
51	INT190571	Gene_expression of Eef2	9	0.35	1.64	0.43
52	INT297675	Negative_regulation of Positive_regulation of Eef1a1	1	0.01	0.92	0.4
53	INT30690	Localization of Eef1a2	2	0.42	0.94	0.39
54	INT147487	Negative_regulation of Gene_expression of Eef1a2	1	0.04	0.34	0.32
55	INT30689	Positive_regulation of Eef1a2	2	0.32	1.18	0.31
56	INT40347	Regulation of Regulation of Eef1a1	1	0.13	0.77	0.3
57	INT176895	Negative_regulation of EEF1A2	3	0.41	0.85	0.29
58	INT40963	Positive_regulation of Binding of Eef1a1	1	0.41	0	0.26
59	INT138921	Regulation of Gene_expression of Eef1a1	1	0.05	0.31	0.25
60	INT40346	Positive_regulation of Regulation of Eef1a1	1	0.14	0.7	0.24
61	INT117144	Negative_regulation of Gene_expression of Eef1a1	1	0.04	0.74	0.24
62	INT176898	Binding of EEF1A2	2	0.36	0.98	0.21
63	INT113786	Regulation of Eef1a2	2	0.33	1.34	0.2
64	INT260912	Positive_regulation of Gene_expression of Eef1a2	2	0.32	0.22	0.19
65	INT157295	Positive_regulation of Gene_expression of EEF1A2	1	0.70	1.57	0.19
66	INT317881	Transcription of Eef1a1	2	0.03	1.38	0.18
67	INT230456	Negative_regulation of Binding of HBS1L	1	0.05	1.73	0.18
68	INT292852	Positive_regulation of Binding of Gfm1	2	0.03	2.56	0.17
69	INT275338	Positive_regulation of Gene_expression of Gfm1	5	0.03	3.14	0.16
70	INT195213	Positive_regulation of Gene_expression of HBS1L	4	0.15	3.5	0.16
71	INT317276	Protein_catabolism of Gfm1	4	0.06	2.41	0.15
72	INT208863	Transcription of Eef2	1	0.24	0	0.14
73	INT164561	Negative_regulation of Negative_regulation of Eef1a2	1	0.01	0.06	0.1
74	INT157292	Positive_regulation of EEF1A2	1	0.70	0.8	0.09
75	INT266513	Localization of Eef1a1	1	0.11	0.82	0.08
76	INT157294	Regulation of EEF1A2	1	0.45	0.76	0.08
77	INT206703	Protein_catabolism of HBS1L	1	0.04	0	0.07
78	INT298902	Positive_regulation of Protein_catabolism of GFM1	1	0.49	0.44	0.06
79	INT292861	Regulation of Binding of Gfm1	1	0.03	0.06	0.06
80	INT93917	Transcription of TCEA1	1	0.13	0	0.05
81	INT275340	Positive_regulation of Localization of Gfm1	3	0.03	1.43	0.04
82	INT197172	Negative_regulation of Gene_expression of Gfm1	2	0.02	1.68	0.04
83	INT298907	Protein_catabolism of GFM1	1	0.86	0.22	0.03
84	INT206698	Regulation of HBS1L	4	0.09	3.06	0
85	INT206695	Gene_expression of GFM1	3	0.58	0.77	0
86	INT196399	Transcription of Gfm1	2	0.01	0.89	0
87	INT238458	Binding of GFM1	2	0.47	1.44	0
88	INT300037	Localization of EEF1A2	2	0.73	2.02	0
89	INT275337	Negative_regulation of Positive_regulation of Gfm1	2	0.02	0.76	0
90	INT93632	Negative_regulation of Gene_expression of TCEA1	1	0.14	0.09	0
91	INT352042	Negative_regulation of Gene_expression of HBS1L	1	0.13	0.76	0
92	INT322725	Positive_regulation of GFM1	1	0.15	1.19	0
93	INT348736	Gene_expression of Eef2	1	0.21	0	0
94	INT352039	Regulation of Gene_expression of HBS1L	1	0.13	0.94	0
95	INT217841	Regulation of EIF5A	1	0.53	0.74	0
96	INT227641	Phosphorylation of Eef2	1	0.80	0.22	0
97	INT217838	Positive_regulation of Regulation of EIF5A	1	0.59	0.74	0
98	INT275339	Regulation of Positive_regulation of Gfm1	1	0.02	0.3	0
99	INT217837	Gene_expression of EIF5A	1	0.51	1.08	0
100	INT217821	Positive_regulation of EIF5A	1	0.18	0.74	0
101	INT224980	Regulation of Eef1a1	1	0.01	0.24	0
102	INT275341	Regulation of Localization of Gfm1	1	0.02	0.3	0
103	INT192424	Negative_regulation of Localization of HBS1L	1	0.01	0.97	0
104	INT323187	Positive_regulation of Transcription of Gfm1	1	0.01	0.15	0
105	INT275336	Negative_regulation of Localization of Gfm1	1	0.02	0.3	0
106	INT298915	Binding of EEF1D	1	0.47	0.06	0