GO:0003774

Name motor activity Categary Function Go Slim No Go Link GO:0003774

Unique Molecular Interactions 75 Total Molecular Interactions 108 Total Single Events 862 Pain Genes Associated 24

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for motor activity. They are ordered first by their pain relevance and then by number of times they were reported for motor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT169346	Nxn Negative_regulation of Dynll1	1	0.06	1.22	1.87
2	INT145473	Mastl Positive_regulation of Dnahc8	1	0.07	0.06	1.33
3	INT296460	Binding of Gria2 and Myo18a	1	0.01	1.49	1.06
4	INT167431	Binding of APP and MYO1C	1	0.23	1.38	0.83
5	INT145472	D2Mit212 Positive_regulation of Dnahc8	1	0.09	0.16	0.81
6	INT89875	Pdyn Positive_regulation of Localization of Myh6	1	0.09	0	0.66
7	INT296475	Binding of Pick1 and Myo18a	2	0.01	1.63	0.57
8	INT146306	Binding of Chrna9 and Myo5c	1	0.01	0.27	0.48
9	INT276207	Binding of Akt1 and Myo1f	1	0.11	0.05	0.47
10	INT335594	Myo5a Regulation of Hmmr	1	0.00	0.39	0.45
11	INT145475	Negative_regulation of D2Mit212 Positive_regulation of Dnahc8	1	0.08	0.1	0.37
12	INT296444	Binding of Rbm39 and Myo18a	1	0.00	0.56	0.36
13	INT145474	D2Mit212 Regulation of Dnahc8	1	0.05	0.08	0.33
14	INT296482	Binding of GRIP1 and Myo18a	1	0.00	0.35	0.32
15	INT302169	PTGER2 Positive_regulation of DYNC1LI1	1	0.02	1.51	0.25
16	INT177661	Binding of Trib3 and Myo1f	1	0.00	0.54	0.24
17	INT296470	Binding of Cacng2 and Myo18a	1	0.00	0.22	0.24
18	INT354723	Binding of ASIC3 and Myo18a	1	0.00	0.25	0.23
19	INT57964	Myo5a Regulation of Negative_regulation of Cyp1a1	1	0.00	0.1	0.2
20	INT41977	Binding of Htr1a and Dync1i2	1	0.02	0.54	0.18
21	INT354703	Binding of ASIC1 and Myo18a	1	0.00	1.11	0.17
22	INT184388	Binding of fc and DNAI1	1	0.01	1.06	0.15
23	INT272607	Binding of Dnahc8 and Nsf	1	0.02	0.42	0.14
24	INT354718	Binding of INADL and Myo18a	1	0.00	0.13	0.12
25	INT322037	Binding of P2RX7 and Myh1	1	0.06	0	0.12
26	INT42067	Rln1 Positive_regulation of Phosphorylation of Myo1f	1	0.11	0.1	0.1
27	INT125745	Nsf Negative_regulation of Dnahc8	1	0.06	0.33	0.1
28	INT124036	Binding of App and Dnahc8	1	0.03	0.14	0.09
29	INT272595	Binding of Dlg4 and Dnahc8	1	0.03	0.21	0.07
30	INT57965	Myo5a Negative_regulation of Cyp2e1	1	0.01	0.09	0.07
31	INT42066	Rln1 Regulation of Phosphorylation of Myo1f	1	0.05	0.07	0.07
32	INT58151	Binding of MYL3 and DMRT3	1	0.00	0.35	0.06
33	INT93415	Binding of Myo5b and Avpr1b	1	0.01	0.26	0.06
34	INT146007	Gene_expression of TRPV1 Positive_regulation of Gene_expression of MYH2	1	0.11	0.06	0.06
35	INT76862	Dynll1 Positive_regulation of Rb1	1	0.37	0.1	0.06
36	INT214015	Negative_regulation of Binding of Dnahc8 and Ank2	1	0.04	1.09	0.04
37	INT214013	Binding of Dnahc8 and Ank2	1	0.03	1.08	0.04
38	INT340556	Binding of Akt1 and Myh1	1	0.04	0.27	0.04
39	INT192678	PTEN Regulation of Dync1h1	1	0.02	0.5	0.03
40	INT218240	Binding of SAE1 and Dync1h1	1	0.00	0.17	0
41	INT322245	Binding of Hcm and Myh7	1	0.11	1.28	0
42	INT340916	hop Regulation of Dnahc8	1	0.02	0.24	0
43	INT303403	Binding of Laptm5 and Myh3	1	0.02	0	0
44	INT303398	Jag1 Positive_regulation of Protein_catabolism of Myh3	1	0.52	0	0
45	INT240420	Myo5a Positive_regulation of CD4	1	0.06	0.27	0
46	INT321770	Binding of Myo15 and Whrn	1	0.43	0.08	0
47	INT303182	Binding of Myo5b and Trim3	1	0.15	0	0
48	INT321772	Binding of Myo7a and Twf2	1	0.00	0	0
49	INT303394	Binding of Myh3 and Mul1	1	0.04	0.38	0
50	INT86996	NGF Regulation of Regulation of DYNLL1	1	0.26	0	0
51	INT290104	Myo7a Regulation of RPE	1	0.03	0.75	0
52	INT271026	Binding of Car2 and Dnahc8	1	0.00	0.44	0
53	INT303399	Binding of Jag1 and Myh3	1	0.50	0.85	0
54	INT263584	Hspa5 Positive_regulation of Myo1b	1	0.00	1.02	0
55	INT354708	Negative_regulation of Binding of ASIC1 and Myo18a	1	0.00	0.13	0
56	INT303392	Mul1 Positive_regulation of Protein_catabolism of Myh3	1	0.06	0	0
57	INT321779	Whrn Positive_regulation of Myo15	1	0.39	0	0
58	INT303171	Binding of Myo5b and Dlgap1	1	0.08	0	0
59	INT303250	Binding of DYNC1LI1 and Dlgap1	1	0.00	0	0
60	INT211673	Tnni2 Negative_regulation of Dnahc8	1	0.06	0.52	0
61	INT255019	Myo7a Positive_regulation of F10	1	0.00	0.06	0
62	INT234164	Binding of Sod1 and Dynll1	1	0.06	1.27	0
63	INT292294	Myh1 Negative_regulation of Transcription of HIVEP1	1	0.00	1.66	0
64	INT131787	Binding of Myo5a and Pon1	1	0.02	0.06	0
65	INT322257	Binding of Mybpc3 and Myh7	1	0.34	0.43	0
66	INT321767	Myo15 Positive_regulation of Gopc	1	0.16	0	0
67	INT211669	Tnni2 Negative_regulation of Dnahc8	1	0.01	0.57	0

Single Events

The table below shows the top 100 pain related interactions that have been reported for motor activity. They are ordered first by their pain relevance and then by number of times they were reported in motor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT1558	Positive_regulation of Dnahc8	30	0.69	5.78	22.19
2	INT1561	Negative_regulation of Dnahc8	59	0.59	18.12	20.99
3	INT1556	Regulation of Dnahc8	20	0.61	3.23	14.44
4	INT57176	Positive_regulation of Dynll1	9	0.49	4.76	7.71
5	INT74099	Negative_regulation of Dynll1	8	0.56	3.43	7.25
6	INT114993	Binding of Myo5a	15	0.30	11.46	5.48
7	INT74393	Gene_expression of Dynll1	8	0.65	2.64	4.39
8	INT33008	Gene_expression of Dync1h1	41	0.68	23.85	3.82
9	INT169344	Positive_regulation of Gene_expression of Dynll1	3	0.49	2.34	3.48
10	INT160251	Gene_expression of Myo5a	48	0.63	37.14	3.16
11	INT27260	Gene_expression of DYNLL1	8	0.75	7.72	2.78
12	INT65642	Binding of Dync1h1	27	0.41	15.83	2.68
13	INT22739	Positive_regulation of DYNLL1	5	0.67	1.69	2.67
14	INT1557	Binding of Dnahc8	6	0.48	1.5	2.51
15	INT74446	Positive_regulation of Dync1h1	25	0.59	13	2.38
16	INT42140	Gene_expression of Myo1f	7	0.19	2.45	2.27
17	INT86999	Regulation of DYNLL1	5	0.44	2.85	2.18
18	INT140298	Positive_regulation of Myo5c	2	0.03	2.1	2.16
19	INT22738	Negative_regulation of DYNLL1	17	0.57	6.68	2.06
20	INT79198	Positive_regulation of Positive_regulation of Dynll1	2	0.42	0.99	1.99
21	INT106793	Positive_regulation of Positive_regulation of Dnahc8	3	0.50	0.58	1.8
22	INT30168	Gene_expression of Dnahc8	20	0.65	4.17	1.73
23	INT42065	Phosphorylation of Myo1f	13	0.38	2.05	1.71
24	INT33431	Localization of Dnahc8	8	0.67	3.49	1.68
25	INT167288	Regulation of Dynll1	3	0.45	1.22	1.56
26	INT159186	Positive_regulation of Gene_expression of DYNLL1	1	0.49	1.25	1.4
27	INT311241	Transcription of Myo5a	1	0.50	1.61	1.37
28	INT1555	Positive_regulation of Regulation of Dnahc8	1	0.46	0	1.33
29	INT140394	Regulation of Dync1h1	7	0.39	2.59	1.25
30	INT155509	Binding of Myo5c	2	0.00	0.85	1.25
31	INT295694	Localization of DNAI1	4	0.15	3.28	1.09
32	INT22095	Negative_regulation of Dync1h1	11	0.48	5.17	1.08
33	INT184384	Gene_expression of DNAI1	8	0.66	5.45	1.05
34	INT88502	Positive_regulation of Negative_regulation of Dnahc8	2	0.48	0.61	1.04
35	INT42138	Binding of Myo1f	5	0.10	1.49	1.03
36	INT75251	Negative_regulation of Positive_regulation of DYNLL1	1	0.41	0.18	0.99
37	INT192785	Regulation of Myo5a	4	0.05	9.05	0.93
38	INT92428	Regulation of Myo7a	2	0.44	1.23	0.91
39	INT295611	Regulation of DNAI1	5	0.23	2.41	0.87
40	INT184386	Binding of DNAI1	5	0.36	3.77	0.82
41	INT124092	Gene_expression of Myo1b	3	0.41	1.22	0.82
42	INT124091	Negative_regulation of Gene_expression of Myo1b	1	0.04	1.08	0.8
43	INT57958	Positive_regulation of Myo5a	9	0.41	7.52	0.77
44	INT131875	Regulation of Regulation of Dnahc8	1	0.26	0.09	0.76
45	INT276176	Negative_regulation of Myo1f	4	0.12	1.85	0.71
46	INT231951	Localization of Myh1	2	0.15	1.18	0.71
47	INT89870	Localization of Myh6	1	0.26	0	0.65
48	INT167735	Positive_regulation of DNAI1	2	0.49	2.88	0.52
49	INT231950	Gene_expression of Myh1	31	0.69	3.7	0.51
50	INT42139	Regulation of Myo1f	3	0.14	0.64	0.49
51	INT231954	Positive_regulation of Gene_expression of Myh1	6	0.45	1.28	0.48
52	INT276175	Positive_regulation of Transcription of Myo1f	1	0.10	1.03	0.47
53	INT102692	Localization of MYH2	1	0.26	0.45	0.47
54	INT276194	Positive_regulation of Gene_expression of Myo1f	1	0.14	1.03	0.47
55	INT276190	Transcription of Myo1f	1	0.11	1.02	0.46
56	INT276191	Negative_regulation of Binding of Myo1f	1	0.09	0.05	0.46
57	INT48418	Localization of Dync1h1	4	0.61	1.54	0.44
58	INT230517	Localization of Myo1f	2	0.15	1.38	0.44
59	INT167432	Binding of MYO1C	1	0.19	0.67	0.41
60	INT109486	Positive_regulation of Negative_regulation of Dynll1	1	0.48	0	0.41
61	INT35501	Positive_regulation of Myo1f	5	0.69	1.73	0.39
62	INT146304	Gene_expression of Myo5c	1	0.03	0.25	0.39
63	INT241875	Transcription of DNAI1	1	0.34	0.71	0.37
64	INT295682	Regulation of Localization of DNAI1	1	0.08	1.87	0.37
65	INT195574	Localization of Myo5a	4	0.34	1.1	0.36
66	INT66251	Negative_regulation of Phosphorylation of Myo1f	1	0.20	0	0.35
67	INT218235	Negative_regulation of Gene_expression of Dync1h1	2	0.37	0.57	0.34
68	INT241877	Phosphorylation of DNAI1	1	0.46	0.71	0.34
69	INT346862	Regulation of Binding of Dync1h1	1	0.39	0.16	0.34
70	INT310948	Negative_regulation of DNAI1	1	0.12	1.63	0.29
71	INT231952	Positive_regulation of Myh1	14	0.62	0.82	0.27
72	INT138093	Protein_catabolism of Myo5c	1	0.87	0.23	0.26
73	INT193545	Binding of Dynll1	2	0.36	0.39	0.25
74	INT302243	Positive_regulation of DYNC1LI1	1	0.04	1.42	0.25
75	INT302262	Negative_regulation of DYNC1LI1	1	0.04	1.36	0.25
76	INT214006	Negative_regulation of Gene_expression of Dnahc8	2	0.03	1.28	0.24
77	INT124643	Binding of DYNLL1	3	0.36	0.9	0.23
78	INT208856	Protein_catabolism of Dnahc8	1	0.06	0	0.23
79	INT170615	Phosphorylation of Dnahc8	1	0.22	0	0.23
80	INT276203	Negative_regulation of Gene_expression of Myo1f	1	0.09	0.38	0.23
81	INT170611	Phosphorylation of Myh1	1	0.79	0	0.23
82	INT208864	Regulation of Protein_catabolism of Dnahc8	1	0.03	0	0.23
83	INT240411	Negative_regulation of Binding of Myo5a	1	0.09	0.97	0.21
84	INT117571	Gene_expression of Myh7	5	0.27	1.43	0.2
85	INT330879	Gene_expression of Myo18a	2	0.02	0.51	0.14
86	INT276193	Regulation of Negative_regulation of Myo1f	1	0.09	0.38	0.14
87	INT192783	Phosphorylation of Myo5a	1	0.04	2.01	0.12
88	INT221195	Positive_regulation of Binding of Dnahc8	1	0.01	0.34	0.11
89	INT303343	Gene_expression of Myh3	1	0.65	0.12	0.1
90	INT341871	Positive_regulation of Binding of Dync1h1	1	0.37	0.61	0.1
91	INT124527	Positive_regulation of Myo7a	1	0.00	0.15	0.1
92	INT58152	Positive_regulation of MYL3	1	0.68	0.45	0.1
93	INT168521	Localization of Myo7a	1	0.18	0.17	0.1
94	INT160258	Negative_regulation of Myo5a	3	0.35	3.96	0.09
95	INT102037	Localization of DYNLL1	2	0.78	0.32	0.08
96	INT58153	Gene_expression of MYL3	1	0.76	0.69	0.08
97	INT193543	Localization of Dynll1	1	0.68	0.17	0.07
98	INT114895	Binding of Myh1	1	0.35	0.29	0.07
99	INT141083	Transcription of Myh1	32	0.64	1.23	0.06
100	INT146008	Gene_expression of MYH2	2	0.32	0.16	0.06
101	INT331180	Positive_regulation of Gene_expression of DNAI1	1	0.49	0.24	0.06
102	INT146010	Positive_regulation of Gene_expression of MYH2	1	0.15	0.06	0.06
103	INT300333	Negative_regulation of Myh1	5	0.52	0.66	0.04
104	INT192784	Positive_regulation of Gene_expression of Myo5a	2	0.45	3.39	0.04
105	INT325356	Regulation of Binding of DNAI1	1	0.44	1.12	0.04
106	INT340545	Positive_regulation of Positive_regulation of Myh1	1	0.10	0.16	0.04
107	INT279098	Positive_regulation of Dynll1	1	0.17	0	0.03
108	INT231953	Regulation of Myh1	3	0.07	0.23	0
109	INT239989	Gene_expression of Myh6	2	0.55	0	0
110	INT178835	Negative_regulation of Binding of Dync1h1	2	0.36	0.85	0
111	INT303379	Positive_regulation of Myh3	1	0.45	0	0
112	INT303360	Positive_regulation of Binding of Myh3	1	0.49	0	0
113	INT239982	Positive_regulation of Positive_regulation of Myh6	1	0.46	0	0
114	INT263567	Positive_regulation of Myo1b	1	0.01	1.01	0
115	INT276524	Regulation of Myo18a	1	0.04	0	0
116	INT286005	Positive_regulation of Binding of Myo5a	1	0.41	0.97	0
117	INT354669	Positive_regulation of Myo18a	1	0.00	0.45	0
118	INT300327	Negative_regulation of Gene_expression of Myh1	1	0.52	0.39	0
119	INT192674	Positive_regulation of Gene_expression of Dync1h1	1	0.32	1.67	0
120	INT239981	Positive_regulation of Myh6	1	0.46	0	0
121	INT303363	Positive_regulation of Regulation of Myh1	1	0.08	0.23	0
122	INT321749	Regulation of Myo15	1	0.37	0.14	0
123	INT239986	Regulation of Myh6	1	0.25	0	0
124	INT158404	Phosphorylation of Dync1h1	1	0.15	0	0
125	INT300324	Regulation of Transcription of Myh1	1	0.24	0.36	0
126	INT234161	Binding of Dynll1	1	0.06	0.46	0
127	INT303359	Positive_regulation of Gene_expression of Myh3	1	0.49	0	0
128	INT102038	Negative_regulation of Localization of DYNLL1	1	0.42	0.24	0
129	INT286004	Positive_regulation of Positive_regulation of Myo5a	1	0.41	0.58	0
130	INT331948	Regulation of Gene_expression of Dnahc8	1	0.02	0.07	0
131	INT300330	Negative_regulation of Transcription of Myh1	1	0.46	0	0
132	INT300325	Positive_regulation of Transcription of Myh1	1	0.54	0.23	0
133	INT303372	Binding of Myh3	1	0.47	0	0
134	INT287856	Positive_regulation of Positive_regulation of Myo1f	1	0.03	0.11	0
135	INT286724	Regulation of Myh3	1	0.26	0	0
136	INT300328	Regulation of Gene_expression of Myh1	1	0.40	0.55	0
137	INT321757	Negative_regulation of Myo15	1	0.31	0.13	0
138	INT276546	Regulation of Myo1b	1	0.16	0	0
139	INT321736	Gene_expression of Myo15	1	0.49	0	0
140	INT303377	Protein_catabolism of Myh3	1	0.96	0	0
141	INT321752	Localization of Myo15	1	0.66	0.16	0
142	INT303368	Localization of Myh3	1	0.73	0	0