GO:0004509

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Name steroid 21-monooxygenase activity
Categary Function
Go Slim No
Go Link GO:0004509
Unique Molecular Interactions 8
Total Molecular Interactions 8
Total Single Events 182
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for steroid 21-monooxygenase activity. They are ordered first by their pain relevance and then by number of times they were reported for steroid 21-monooxygenase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT29599 Binding of Cyp21a1 and Adarb1 1 0.01 0 1.38
2 INT151637 Binding of Cyp21a1 and Ear11 1 0.01 0 0.44
3 INT61660 Binding of CHAT and CYP21A2 1 0.00 0 0.4
4 INT323042 Binding of CYP21A2 and HLA-DOA 1 0.04 1.49 0.06
5 INT180373 CYP2A6 Regulation of Cyp2d4 1 0.05 2.01 0.05
6 INT20325 Binding of CYP2D6 and CYP21A2 1 0.00 0 0
7 INT20326 Binding of CYP1A2 and CYP21A2 1 0.01 0 0
8 INT20321 Binding of CYP2E1 and CYP21A2 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for steroid 21-monooxygenase activity. They are ordered first by their pain relevance and then by number of times they were reported in steroid 21-monooxygenase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT68347 Negative_regulation of Cyp2d4 34 0.58 7.62 18.35
2 INT22834 Negative_regulation of CYP21A2 28 0.58 23.07 7.13
3 INT23952 Gene_expression of Cyp2d4 18 0.78 4.76 5.31
4 INT230829 Localization of Cyp2d4 3 0.63 0.61 5.18
5 INT60188 Positive_regulation of Cyp2d4 10 0.70 1.04 4.35
6 INT180338 Binding of Cyp2d4 12 0.47 6.87 4.09
7 INT60339 Gene_expression of CYP21A2 8 0.66 4.04 2.77
8 INT180343 Negative_regulation of Negative_regulation of Cyp2d4 2 0.36 0.49 2.38
9 INT29598 Binding of Cyp21a1 5 0.31 0.09 1.71
10 INT10576 Gene_expression of Cyp21a1 7 0.44 1.62 1.32
11 INT145488 Regulation of Cyp2d4 5 0.45 1.1 1.19
12 INT10574 Positive_regulation of Cyp21a1 5 0.44 0.18 1.09
13 INT24297 Regulation of CYP21A2 3 0.05 1.29 1.09
14 INT71349 Negative_regulation of Cyp21a1 3 0.42 1.7 1.04
15 INT217950 Positive_regulation of Negative_regulation of CYP21A2 2 0.03 1.34 0.97
16 INT331007 Negative_regulation of Gene_expression of CYP21A2 1 0.02 1.34 0.97
17 INT10571 Regulation of Cyp21a1 3 0.26 0 0.85
18 INT138040 Regulation of Gene_expression of CYP21A2 1 0.00 0.58 0.72
19 INT10573 Regulation of Gene_expression of Cyp21a1 1 0.01 0 0.64
20 INT10577 Transcription of Cyp21a1 1 0.01 0 0.64
21 INT10569 Regulation of Transcription of Cyp21a1 1 0.01 0 0.35
22 INT44058 Localization of CYP21A2 2 0.74 0.73 0.27
23 INT347186 Regulation of Negative_regulation of Cyp2d4 1 0.45 0.21 0.25
24 INT93748 Regulation of Positive_regulation of Cyp21a1 1 0.03 0 0.19
25 INT261231 Negative_regulation of Gene_expression of Cyp2d4 2 0.42 0.36 0.14
26 INT146889 Positive_regulation of CYP21A2 1 0.39 0 0.12
27 INT113802 Transcription of Cyp2d4 1 0.69 0 0.11
28 INT46801 Negative_regulation of Binding of Cyp21a1 1 0.35 0.09 0.09
29 INT31482 Regulation of Binding of Cyp21a1 1 0.23 0 0.06
30 INT180329 Positive_regulation of Binding of Cyp2d4 1 0.33 1.97 0.05
31 INT264053 Positive_regulation of Negative_regulation of Cyp2d4 1 0.25 0.18 0.03
32 INT323048 Binding of CYP21A2 1 0.37 1.9 0
33 INT180326 Regulation of Gene_expression of Cyp2d4 1 0.18 0.77 0
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