GO:0004510

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Latest revision as of 00:07, 30 January 2013

Name tryptophan 5-monooxygenase activity
Categary Function
Go Slim No
Go Link GO:0004510
Unique Molecular Interactions 8
Total Molecular Interactions 8
Total Single Events 220
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

[edit] Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for tryptophan 5-monooxygenase activity. They are ordered first by their pain relevance and then by number of times they were reported for tryptophan 5-monooxygenase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT189303 Atp6v1e1 Positive_regulation of Gene_expression of TPH1 1 0.01 0.16 0.73
2 INT160156 Tph2 Regulation of Htr1a 1 0.30 0.75 0.56
3 INT352821 Tph2 Regulation of Tst 1 0.31 0.46 0.36
4 INT335888 Lrp5 Negative_regulation of Gene_expression of Tph1 1 0.22 0.15 0.21
5 INT208763 Binding of CSF2 and TPH1 1 0.07 0.65 0.19
6 INT258614 Positive_regulation of Binding of Foxn1 and Tph2 1 0.46 0.06 0
7 INT258615 Binding of Foxn1 and Tph2 1 0.44 0.06 0

[edit] Single Events

The table below shows the top 100 pain related interactions that have been reported for tryptophan 5-monooxygenase activity. They are ordered first by their pain relevance and then by number of times they were reported in tryptophan 5-monooxygenase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT149015 Gene_expression of Tph2 20 0.78 9.45 10.4
2 INT115296 Gene_expression of TPH1 18 0.77 7.46 10.18
3 INT167457 Negative_regulation of Gene_expression of Tph2 5 0.57 2.27 5.9
4 INT126659 Gene_expression of Tph1 22 0.78 2.04 4.04
5 INT137301 Negative_regulation of Gene_expression of TPH1 5 0.12 1.49 2.98
6 INT248419 Negative_regulation of Tph2 11 0.59 6.32 2.59
7 INT115298 Regulation of Gene_expression of TPH1 1 0.22 2.36 2.33
8 INT61011 Regulation of TPH1 4 0.22 1.17 2.09
9 INT248418 Localization of Tph2 5 0.75 2.45 1.45
10 INT126660 Positive_regulation of Gene_expression of Tph1 5 0.50 0.07 1.43
11 INT122745 Negative_regulation of TPH1 6 0.59 2.94 1.2
12 INT115294 Regulation of Regulation of TPH1 2 0.10 1 0.98
13 INT248421 Regulation of Tph1 1 0.27 0.89 0.87
14 INT344348 Transcription of Tph2 1 0.71 0.98 0.87
15 INT344349 Positive_regulation of Gene_expression of Tph2 1 0.46 0.77 0.8
16 INT208774 Positive_regulation of TPH1 2 0.50 0.71 0.78
17 INT344350 Positive_regulation of Tph2 1 0.69 0.82 0.78
18 INT149014 Negative_regulation of Tph1 5 0.58 1.43 0.74
19 INT149013 Positive_regulation of Tph1 3 0.47 1.1 0.65
20 INT61009 Negative_regulation of Regulation of TPH1 1 0.00 0 0.5
21 INT353976 Negative_regulation of Negative_regulation of Tph2 1 0.42 0 0.35
22 INT248415 Binding of Tph2 9 0.44 3.88 0.34
23 INT332750 Regulation of Gene_expression of Tph1 1 0.11 0 0.33
24 INT268069 Regulation of Tph2 1 0.44 0.26 0.28
25 INT353977 Regulation of Gene_expression of Tph2 1 0.26 0 0.24
26 INT335879 Negative_regulation of Gene_expression of Tph1 1 0.19 0.15 0.21
27 INT248417 Binding of Tph1 1 0.37 1.16 0.16
28 INT248416 Phosphorylation of Tph1 1 0.80 1.04 0.13
29 INT248422 Negative_regulation of Phosphorylation of Tph1 1 0.42 1.04 0.13
30 INT248420 Negative_regulation of Phosphorylation of Tph2 1 0.43 0.99 0.11
31 INT248423 Phosphorylation of Tph2 1 0.81 0.99 0.11
32 INT208775 Binding of TPH1 1 0.37 0.61 0.1
33 INT268076 Positive_regulation of Positive_regulation of Tph1 1 0.28 0.83 0.08
34 INT200429 Positive_regulation of Negative_regulation of TPH1 1 0.01 0.24 0.07
35 INT138234 Transcription of Tph1 1 0.66 0 0
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