GO:0004791

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Name thioredoxin-disulfide reductase activity
Categary Function
Go Slim No
Go Link GO:0004791
Unique Molecular Interactions 14
Total Molecular Interactions 15
Total Single Events 199
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for thioredoxin-disulfide reductase activity. They are ordered first by their pain relevance and then by number of times they were reported for thioredoxin-disulfide reductase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT169346 Nxn Negative_regulation of Dynll1 1 0.06 1.22 1.87
2 INT162932 TXNRD1 Negative_regulation of Phosphorylation of AKT1 1 0.14 1.01 0.47
3 INT162931 TXNRD1 Negative_regulation of Phosphorylation of NQO1 1 0.13 0.5 0.23
4 INT39567 Txnrd1 Regulation of Localization of Il1f5 1 0.04 0.18 0.21
5 INT38206 Acr Negative_regulation of Txnrd1 1 0.20 0.08 0.08
6 INT297374 Binding of TXNRD1 and Rxra 1 0.01 0.2 0.03
7 INT98354 TXNRD1 Positive_regulation of Positive_regulation of ESR1 1 0.00 0.05 0
8 INT98355 TXNRD1 Negative_regulation of Positive_regulation of ESR1 1 0.00 0.09 0
9 INT95055 Binding of CYP1A2 and TXNRD1 1 0.04 0 0
10 INT274705 Binding of TXNRD1 and Dh 1 0.00 0 0
11 INT210164 Binding of TXN and TXNRD1 1 0.04 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for thioredoxin-disulfide reductase activity. They are ordered first by their pain relevance and then by number of times they were reported in thioredoxin-disulfide reductase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT39507 Positive_regulation of TXNRD1 37 0.68 12.47 14.25
2 INT100772 Negative_regulation of TXNRD1 10 0.41 3.47 4.74
3 INT35765 Gene_expression of TXNRD1 47 0.56 9.16 4.43
4 INT33951 Regulation of TXNRD1 18 0.51 6.97 4.02
5 INT57957 Localization of TXNRD1 14 0.64 4.01 2.7
6 INT169345 Negative_regulation of Nxn 1 0.07 1.16 1.85
7 INT70615 Binding of TXNRD1 25 0.36 12.15 1.27
8 INT110859 Negative_regulation of Positive_regulation of TXNRD1 1 0.41 0.65 0.82
9 INT351236 Negative_regulation of Negative_regulation of TXNRD1 1 0.22 0.06 0.44
10 INT38203 Negative_regulation of Txnrd1 4 0.39 0.27 0.35
11 INT98363 Positive_regulation of Gene_expression of TXNRD1 8 0.35 0.29 0.24
12 INT144156 Negative_regulation of Localization of TXNRD1 1 0.47 0 0.11
13 INT156816 Regulation of Txnrd1 1 0.22 0 0.1
14 INT276800 Transcription of TXNRD1 2 0.19 0.36 0.07
15 INT128408 Positive_regulation of Positive_regulation of TXNRD1 2 0.30 0 0
16 INT276805 Negative_regulation of Gene_expression of TXNRD1 1 0.13 0 0
17 INT210663 Positive_regulation of Txnrd1 1 0.05 0.1 0
18 INT57804 Localization of Txnrd1 1 0.61 0.07 0
19 INT210665 Transcription of Txnrd1 1 0.06 0.09 0
20 INT123080 Regulation of Regulation of TXNRD1 1 0.01 0 0
21 INT188052 Positive_regulation of Txnrd1 1 0.23 0.25 0
22 INT98362 Positive_regulation of Binding of TXNRD1 1 0.02 0.07 0
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