GO:0004911

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Name interleukin-2 receptor activity
Categary Function
Go Slim No
Go Link GO:0004911
Unique Molecular Interactions 29
Total Molecular Interactions 32
Total Single Events 689
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for interleukin-2 receptor activity. They are ordered first by their pain relevance and then by number of times they were reported for interleukin-2 receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT103930 Cps1 Negative_regulation of Gene_expression of Il2ra 1 0.02 0.25 0.93
2 INT134785 Il2rb Regulation of Gene_expression of IL6 1 0.00 1.16 0.92
3 INT134784 Il2rb Regulation of IL6 1 0.00 1.16 0.92
4 INT134782 Il2rb Regulation of Gene_expression of Crp 1 0.00 1.16 0.92
5 INT178577 CNTN2 Positive_regulation of IL2RA 1 0.03 2.16 0.75
6 INT329961 Binding of IL2RA and PTPN22 1 0.35 1.87 0.63
7 INT103936 Cps1 Negative_regulation of Il2ra 1 0.02 0.07 0.46
8 INT337325 PIK3CD Positive_regulation of Phosphorylation of IL2RG 1 0.00 0 0.43
9 INT351007 Binding of IL2 and IL2RA 1 0.33 1.33 0.26
10 INT338421 Il2ra Negative_regulation of Gene_expression of Ik 1 0.00 1.27 0.22
11 INT18965 TNF Positive_regulation of IL2RA 1 0.06 0.83 0.2
12 INT289958 Binding of IL2 and IL2RB 1 0.02 0.59 0.12
13 INT351009 IL2RG Positive_regulation of Transcription of IL2 1 0.27 0.44 0.05
14 INT351012 IL2RB Positive_regulation of Gene_expression of IL15 1 0.10 0.42 0.05
15 INT351008 IL2RB Positive_regulation of Gene_expression of IL2 1 0.18 0.42 0.05
16 INT178574 IL2RA Positive_regulation of Gene_expression of Cd3e 1 0.04 0.16 0.05
17 INT248953 Il2ra Regulation of Gene_expression of Cd4 1 0.20 0 0.04
18 INT226506 Maf Positive_regulation of Positive_regulation of Il2ra 1 0.02 0.22 0.04
19 INT130222 IL2 Positive_regulation of Il2rb 1 0.00 0 0
20 INT256386 Il2ra Positive_regulation of Cd4 1 0.41 0.15 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for interleukin-2 receptor activity. They are ordered first by their pain relevance and then by number of times they were reported in interleukin-2 receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT10187 Gene_expression of Il2ra 91 0.78 52.67 16.66
2 INT16322 Gene_expression of Il2rb 19 0.51 15.88 12.18
3 INT5788 Gene_expression of IL2RA 60 0.75 40.67 9.98
4 INT56564 Negative_regulation of Gene_expression of Il2rb 1 0.38 0 6.97
5 INT11747 Positive_regulation of IL2RA 22 0.67 16.55 6.95
6 INT27628 Gene_expression of IL2RG 28 0.75 20.95 6.16
7 INT35028 Positive_regulation of IL2RG 14 0.47 10.05 4.36
8 INT56562 Positive_regulation of Gene_expression of Il2rb 6 0.45 3.17 4.34
9 INT10188 Positive_regulation of Il2ra 19 0.45 11.6 3.37
10 INT61087 Positive_regulation of Gene_expression of Il2ra 12 0.35 9.1 3.25
11 INT10189 Negative_regulation of Gene_expression of Il2ra 8 0.32 8.05 2.91
12 INT56150 Localization of IL2RG 7 0.45 2.74 2.68
13 INT83325 Regulation of Gene_expression of Il2ra 8 0.48 3.59 2.36
14 INT36100 Positive_regulation of Il2rb 7 0.49 4.18 2.32
15 INT36052 Positive_regulation of Gene_expression of IL2RG 7 0.28 4.72 2.32
16 INT47914 Regulation of Il2ra 5 0.18 3.05 1.86
17 INT25163 Positive_regulation of Gene_expression of IL2RA 8 0.45 5.37 1.71
18 INT46766 Negative_regulation of Il2ra 9 0.57 5.27 1.64
19 INT100586 Localization of Il2rb 6 0.15 3.18 1.64
20 INT157357 Binding of IL2RA 6 0.44 5.18 1.63
21 INT99358 Positive_regulation of Localization of IL2RG 1 0.28 0.51 1.53
22 INT22067 Positive_regulation of IL2RB 11 0.70 5.74 1.23
23 INT82443 Negative_regulation of Positive_regulation of Il2ra 1 0.05 0 0.86
24 INT64827 Binding of Il2ra 5 0.36 6.57 0.79
25 INT50954 Regulation of IL2RA 5 0.25 3.09 0.77
26 INT11049 Gene_expression of IL2RB 8 0.60 3.73 0.76
27 INT56136 Localization of IL2RB 3 0.59 1.99 0.67
28 INT88051 Regulation of Gene_expression of IL2RG 2 0.24 1.57 0.65
29 INT48801 Positive_regulation of Gene_expression of IL2RB 2 0.47 1.44 0.61
30 INT100588 Positive_regulation of Localization of Il2rb 1 0.09 0.52 0.53
31 INT178589 Localization of IL2RA 3 0.68 1.99 0.45
32 INT100587 Negative_regulation of Localization of Il2rb 1 0.11 0.23 0.41
33 INT289974 Binding of IL2RB 3 0.11 1.59 0.4
34 INT337346 Phosphorylation of IL2RG 1 0.01 0 0.4
35 INT228102 Localization of Il2ra 2 0.52 0.74 0.37
36 INT95834 Negative_regulation of Gene_expression of IL2RG 1 0.02 0.1 0.34
37 INT150252 Negative_regulation of IL2RA 3 0.41 1.73 0.23
38 INT60017 Regulation of Il2rb 1 0.01 0.71 0.23
39 INT351017 Binding of IL2RG 1 0.17 0.44 0.16
40 INT11050 Regulation of Gene_expression of IL2RA 3 0.41 1.4 0.15
41 INT157356 Negative_regulation of Gene_expression of IL2RA 1 0.07 1.14 0.14
42 INT52969 Regulation of IL2RB 2 0.06 0 0.12
43 INT60016 Negative_regulation of Il2rb 2 0.02 2.26 0.08
44 INT123904 Positive_regulation of Positive_regulation of Il2ra 1 0.14 0.34 0.08
45 INT276306 Transcription of Il2ra 1 0.07 1.04 0.07
46 INT351018 Phosphorylation of IL2RA 1 0.79 0.64 0.05
47 INT254584 Transcription of Il2rb 1 0.01 0 0.05
48 INT229183 Positive_regulation of Localization of IL2RB 1 0.39 0.37 0.05
49 INT351014 Transcription of IL2RA 1 0.48 1.54 0.05
50 INT52968 Regulation of Gene_expression of IL2RB 2 0.16 1.57 0
51 INT125015 Regulation of Positive_regulation of Il2ra 1 0.06 0 0
52 INT52967 Regulation of Positive_regulation of IL2RB 1 0.06 0 0
53 INT160503 Negative_regulation of Binding of Il2ra 1 0.03 0 0
54 INT195214 Positive_regulation of Positive_regulation of IL2RG 1 0.04 0 0
55 INT279322 Regulation of Gene_expression of Il2rb 1 0.14 0.3 0
56 INT229189 Transcription of IL2RB 1 0.42 0.32 0
57 INT237159 Phosphorylation of Il2ra 1 0.15 0 0
58 INT279323 Binding of Il2rb 1 0.09 1.86 0
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