GO:0005260

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Latest revision as of 20:26, 25 January 2013

Name channel-conductance-controlling ATPase activity
Categary Function
Go Slim No
Go Link GO:0005260
Unique Molecular Interactions 25
Total Molecular Interactions 31
Total Single Events 605
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

[edit] Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for channel-conductance-controlling ATPase activity. They are ordered first by their pain relevance and then by number of times they were reported for channel-conductance-controlling ATPase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT162419 Binding of Abpa and Cftr 1 0.04 1.66 1.19
2 INT170832 Cftr Regulation of Scnn1a 2 0.16 1.2 0.67
3 INT170833 Cftr Negative_regulation of Slc10a2 1 0.47 0.31 0.56
4 INT69291 Cftr Positive_regulation of Localization of Slc4a8 1 0.04 0.38 0.51
5 INT117482 CFTR Negative_regulation of THRB 1 0.01 0.15 0.51
6 INT341623 Binding of CFTR and CTRC 1 0.35 1.22 0.46
7 INT341624 Binding of CFTR and PRSS1 1 0.39 1.01 0.45
8 INT352547 Binding of CFTR and DMD 1 0.01 1.42 0.35
9 INT310696 Tlr4 Positive_regulation of Positive_regulation of Cftr 1 0.16 0.74 0.28
10 INT196695 Prkaca Positive_regulation of CFTR 1 0.46 0.13 0.27
11 INT274697 Binding of CFTR and Cftr 1 0.08 0.69 0.27
12 INT170834 Cftr Regulation of Slc10a2 1 0.58 0.37 0.22
13 INT196635 CFTR Positive_regulation of Gene_expression of CCL5 1 0.07 0.44 0.21
14 INT196610 IFNG Negative_regulation of CFTR 1 0.17 0.21 0.19
15 INT267660 CFTR Regulation of Gene_expression of P2RX2 1 0.25 0.51 0.18
16 INT196606 IFNG Positive_regulation of CFTR 1 0.16 0.45 0.16
17 INT127206 Negative_regulation of Cftr Negative_regulation of Positive_regulation of Mcf2l 1 0.16 0.62 0.16
18 INT196608 TNF Negative_regulation of CFTR 1 0.16 0.11 0.14
19 INT216545 Gene_expression of Cftr Negative_regulation of Kcnma1 1 0.00 0.59 0.06
20 INT196639 Negative_regulation of NA Negative_regulation of Transcription of CFTR 1 0.02 0.63 0.03
21 INT213585 Binding of CFTR and FLNA 1 0.14 0.11 0.03
22 INT310694 Tlr4 Positive_regulation of Cftr 1 0.16 0.34 0.03
23 INT308747 Binding of Cftr and Prkag1 1 0.02 0 0
24 INT247030 Prkaca Regulation of Positive_regulation of Cftr 1 0.05 0 0

[edit] Single Events

The table below shows the top 100 pain related interactions that have been reported for channel-conductance-controlling ATPase activity. They are ordered first by their pain relevance and then by number of times they were reported in channel-conductance-controlling ATPase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT103842 Gene_expression of Cftr 53 0.78 59.59 21.82
2 INT84307 Binding of Cftr 31 0.47 26.19 12.8
3 INT119892 Gene_expression of Cftr 54 0.77 23.76 9.73
4 INT77282 Positive_regulation of Cftr 23 0.69 21.8 9.65
5 INT101891 Negative_regulation of Cftr 25 0.58 24.09 9.55
6 INT138802 Gene_expression of CFTR 36 0.70 18.8 7.02
7 INT69289 Negative_regulation of Cftr 44 0.57 13.28 6.97
8 INT86119 Regulation of Cftr 13 0.45 14.08 5.75
9 INT151102 Positive_regulation of CFTR 22 0.61 15.27 5.12
10 INT89114 Binding of Cftr 13 0.37 11.29 4.99
11 INT170757 Positive_regulation of Gene_expression of Cftr 3 0.51 11.41 4.75
12 INT169756 Binding of CFTR 9 0.35 9.65 4.55
13 INT48993 Positive_regulation of Cftr 17 0.57 6.02 4.12
14 INT89113 Regulation of Cftr 11 0.62 6.83 4.01
15 INT151099 Negative_regulation of CFTR 12 0.59 10.28 3.79
16 INT69290 Localization of Cftr 11 0.75 3.69 2.52
17 INT86315 Transcription of Cftr 7 0.53 4.24 2.3
18 INT202522 Negative_regulation of Gene_expression of Cftr 11 0.57 5.9 2.24
19 INT166710 Positive_regulation of Gene_expression of CFTR 9 0.46 3.72 2.03
20 INT119891 Regulation of Gene_expression of Cftr 4 0.59 2.67 1.98
21 INT151101 Regulation of CFTR 4 0.62 3.69 1.89
22 INT84308 Localization of Cftr 12 0.75 6.16 1.65
23 INT108281 Negative_regulation of Binding of Cftr 4 0.43 3.1 1.38
24 INT139625 Regulation of Gene_expression of Cftr 5 0.50 3.59 1.32
25 INT196675 Localization of CFTR 4 0.64 1.95 1.19
26 INT86314 Regulation of Transcription of Cftr 2 0.33 1.81 0.83
27 INT61290 Regulation of Phosphorylation of CFTR 1 0.44 0.25 0.81
28 INT274693 Positive_regulation of Gene_expression of Cftr 6 0.49 2.93 0.8
29 INT61291 Phosphorylation of CFTR 1 0.80 0.25 0.8
30 INT196682 Negative_regulation of Gene_expression of CFTR 6 0.34 1.96 0.73
31 INT151100 Negative_regulation of Positive_regulation of CFTR 1 0.43 1.11 0.73
32 INT127204 Negative_regulation of Positive_regulation of Cftr 1 0.43 1.9 0.69
33 INT215828 Regulation of Binding of Cftr 2 0.33 1.56 0.66
34 INT103841 Negative_regulation of Gene_expression of Cftr 3 0.43 1.93 0.63
35 INT151098 Positive_regulation of Positive_regulation of CFTR 2 0.50 0.9 0.63
36 INT170759 Positive_regulation of Binding of Cftr 2 0.50 1.82 0.6
37 INT348872 Positive_regulation of Regulation of Cftr 1 0.34 1.3 0.55
38 INT310689 Positive_regulation of Negative_regulation of Cftr 1 0.47 1.41 0.4
39 INT226184 Protein_catabolism of Cftr 3 0.87 1.52 0.38
40 INT170758 Positive_regulation of Localization of Cftr 2 0.50 2.4 0.35
41 INT170756 Negative_regulation of Localization of Cftr 1 0.42 1.74 0.31
42 INT267666 Regulation of Localization of CFTR 1 0.22 0.39 0.3
43 INT120959 Protein_catabolism of CFTR 1 0.03 0.14 0.28
44 INT132710 Negative_regulation of Regulation of Cftr 1 0.06 0.1 0.27
45 INT196688 Positive_regulation of Binding of CFTR 1 0.26 0.33 0.24
46 INT308734 Transcription of Cftr 1 0.68 0.75 0.2
47 INT196681 Negative_regulation of Localization of CFTR 1 0.34 0.18 0.15
48 INT310692 Positive_regulation of Protein_catabolism of Cftr 1 0.44 0.46 0.12
49 INT196672 Positive_regulation of Localization of CFTR 1 0.41 0 0.1
50 INT347555 Positive_regulation of Localization of Cftr 1 0.14 0.63 0.09
51 INT308732 Regulation of Transcription of Cftr 1 0.44 0.18 0.09
52 INT308735 Negative_regulation of Positive_regulation of Cftr 1 0.42 0.15 0.08
53 INT196673 Regulation of Gene_expression of CFTR 1 0.36 0.62 0.08
54 INT274694 Negative_regulation of Binding of Cftr 1 0.35 0.19 0.05
55 INT196683 Negative_regulation of Transcription of CFTR 1 0.22 0.61 0.03
56 INT196685 Transcription of CFTR 1 0.37 0.6 0.03
57 INT308731 Phosphorylation of Cftr 1 0.62 0 0
58 INT216564 Regulation of Negative_regulation of Cftr 1 0.24 0.12 0
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