GO:0005509

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Name calcium ion binding
Categary Function
Go Slim No
Go Link GO:0005509
Unique Molecular Interactions 3185
Total Molecular Interactions 4350
Total Single Events 30896
Pain Genes Associated 399

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for calcium ion binding. They are ordered first by their pain relevance and then by number of times they were reported for calcium ion binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT324068 Binding of GCH1 and SNRNP70 1 0.01 28.19 40.6
2 INT296275 Binding of Dlg4 and Kcnip3 1 0.39 3.58 5.6
3 INT215943 Binding of Mmp14 and Timp2 1 0.21 1.59 3.33
4 INT275850 Binding of NDUFAB1 and SNCA 1 0.00 3.78 3.16
5 INT251146 Binding of Grin1 and Dlg2 1 0.36 1.95 3.16
6 INT101408 Binding of Grin1 and Olr1469 1 0.03 0.86 3.1
7 INT101407 Binding of Grin1 and Spr 1 0.14 0.86 3.09
8 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01
9 INT156381 Binding of Grin1 and Dlg4 1 0.39 0.86 2.9
10 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79
11 INT190167 Binding of JUN and MMP12 1 0.26 0.82 2.76
12 INT91350 Binding of Pla2g4a and RYBP 1 0.00 1.15 2.65
13 INT351444 Grin1 Positive_regulation of Gria2 1 0.22 1.5 2.64
14 INT121698 HRAS Negative_regulation of Gene_expression of MMP3 1 0.06 0.5 2.6
15 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52
16 INT317528 Ppp1r9b Regulation of Grin1 1 0.18 0.2 2.48
17 INT287746 Anxa1 Positive_regulation of Gene_expression of Lpar1 1 0.07 1.72 2.46
18 INT139723 PROC Positive_regulation of MAPK8 1 0.01 2.98 2.33
19 INT156622 Umod Regulation of Phosphorylation of Creb1 1 0.05 0.33 2.27
20 INT156623 Umod Regulation of Phosphorylation of Ephb1 1 0.05 0.33 2.27
21 INT134872 Binding of Calm3 and IQCJ 1 0.00 0.82 2.26
22 INT317524 Binding of Camk2a and Grin1 1 0.17 0.06 2.21
23 INT296277 Binding of Car2 and Kcnip3 5 0.18 1.09 2.06
24 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
25 INT207630 Binding of Calm3 and Nrgn 1 0.06 1.03 1.82
26 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81
27 INT192161 Mmp14 Positive_regulation of Mmp2 2 0.19 1.23 1.81
28 INT272616 Positive_regulation of Binding of Grin1 and Grin2a 2 0.30 1.36 1.8
29 INT115048 Kcnip3 Regulation of Gene_expression of Pdyn 2 0.27 0.71 1.78
30 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
31 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75
32 INT266391 Binding of Ager and S100a1 1 0.01 5.63 1.69
33 INT30134 Binding of TPP1 and S100A9 1 0.13 0.74 1.69
34 INT324067 Regulation of Binding of GCH1 and SNRNP70 1 0.01 0.95 1.67
35 INT151889 Binding of Adarb1 and DLL1 1 0.00 0 1.66
36 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
37 INT236491 GCH1 Regulation of Pain1 1 0.01 0.89 1.65
38 INT147652 PLCB1 Negative_regulation of Positive_regulation of TRPV1 1 0.27 0.92 1.62
39 INT32937 Binding of Pgrmc1 and Dtnb 1 0.20 0 1.61
40 INT131575 Grin1 Negative_regulation of Positive_regulation of Ephb1 1 0.28 0.31 1.58
41 INT130839 Gfap Positive_regulation of S100B 1 0.51 1.9 1.56
42 INT148821 Binding of Oprm1 and Grin1 1 0.05 0.24 1.55
43 INT284785 Gch1 Regulation of Bh4p 1 0.00 1.48 1.54
44 INT112033 Gabrb3 Positive_regulation of Plcg1 1 0.05 0.18 1.49
45 INT298283 Pou4f1 Positive_regulation of Gene_expression of Runx1 1 0.50 1.4 1.48
46 INT140329 Grin1 Negative_regulation of Ltp 1 0.04 0.64 1.46
47 INT161871 Mors1 Positive_regulation of GRIN1 1 0.01 0.12 1.46
48 INT131039 Binding of Oprm1 and Prf1 1 0.17 0 1.45
49 INT131041 Negative_regulation of Binding of Oprm1 and Prf1 1 0.21 0 1.45
50 INT131040 Binding of Oprm1 and S100a9 1 0.24 0 1.45
51 INT161858 OPRM1 Positive_regulation of GRIN1 1 0.50 0.12 1.45
52 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
53 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
54 INT96262 Positive_regulation of Pik3cd Positive_regulation of Plcg1 1 0.03 0 1.39
55 INT60993 Ntf4 Negative_regulation of Positive_regulation of CRTAC1 1 0.00 0 1.37
56 INT60992 Ngf Regulation of CRTAC1 1 0.00 0 1.35
57 INT317519 Grin1 Positive_regulation of Negative_regulation of Oprm1 1 0.14 0 1.31
58 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3
59 INT139722 PROC Positive_regulation of CDCP1 1 0.00 1.61 1.29
60 INT135830 Gch1 Regulation of Nos2 1 0.65 0 1.29
61 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28
62 INT168866 Binding of RYR1 and Cd38 1 0.02 0.17 1.28
63 INT154203 Binding of Pick1 and Grm7 1 0.41 1.64 1.28
64 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27
65 INT139724 PROC Positive_regulation of MAPK14 1 0.00 1.57 1.25
66 INT202039 CAMK2N2 Negative_regulation of MMP1 1 0.00 0.73 1.24
67 INT21858 Maoa Regulation of Gene_expression of Spna1 1 0.12 0.18 1.24
68 INT202036 CAMK2N2 Negative_regulation of MMP3 1 0.00 0.73 1.24
69 INT21859 Maoa Regulation of Spna1 1 0.12 0.18 1.23
70 INT70028 LTA Regulation of PRF1 1 0.02 1.42 1.21
71 INT70035 TNF Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
72 INT70045 IL12A Regulation of Negative_regulation of PRF1 1 0.04 1.42 1.21
73 INT70032 TNF Regulation of PRF1 1 0.05 1.42 1.21
74 INT70042 LTA Regulation of Negative_regulation of PRF1 1 0.02 1.42 1.21
75 INT70033 IL6 Regulation of PRF1 1 0.03 1.42 1.21
76 INT70038 IL1B Regulation of PRF1 1 0.05 1.42 1.21
77 INT70031 IL1B Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
78 INT70044 IL12A Regulation of PRF1 1 0.04 1.42 1.21
79 INT301166 LRP2 Regulation of TRD@ 1 0.12 1.93 1.21
80 INT70047 IL6 Regulation of Negative_regulation of PRF1 1 0.03 1.42 1.21
81 INT264333 IL-17 Positive_regulation of Gene_expression of Mmp1a 1 0.05 2.88 1.18
82 INT220751 EGF Regulation of GOPC 1 0.08 0 1.18
83 INT220752 Negative_regulation of EGF Regulation of NAV1 1 0.26 0 1.18
84 INT220753 Negative_regulation of EGF Regulation of GOPC 1 0.08 0 1.18
85 INT134871 Negative_regulation of Binding of Calm3 and IQCJ 1 0.00 0.41 1.17
86 INT220748 EGF Regulation of NAV1 1 0.28 0 1.17
87 INT180814 Binding of Ret and Gdnf 1 0.01 1.31 1.17
88 INT207116 F2 Positive_regulation of F2r 5 0.12 2.16 1.16
89 INT290667 Il6 Positive_regulation of Stat3 3 0.69 2.42 1.15
90 INT308172 Rvm Positive_regulation of Phosphorylation of GRIN1 1 0.50 0.68 1.14
91 INT317553 Binding of Car2 and Grin1 1 0.07 0 1.14
92 INT66767 Il1b Positive_regulation of Pla2g10 1 0.05 0.47 1.13
93 INT68160 Alox5 Positive_regulation of Positive_regulation of Pla2g1b 1 0.03 0.64 1.13
94 INT68156 Pla2g1b Positive_regulation of Positive_regulation of Alox5 1 0.03 0.64 1.13
95 INT163799 Binding of GRIN1 and Rvm 1 0.16 0.96 1.13
96 INT68158 Pla2g1b Positive_regulation of Pdpk1 1 0.05 0.63 1.12
97 INT68159 Pla2g1b Positive_regulation of Positive_regulation of Pdpk1 1 0.05 0.64 1.12
98 INT332776 FSCN1 Positive_regulation of Grin1 1 0.02 0.21 1.12
99 INT68161 Mthfs Positive_regulation of Positive_regulation of Pla2g1b 1 0.03 0.64 1.12
100 INT68155 Pla2g1b Positive_regulation of Positive_regulation of Mthfs 1 0.03 0.64 1.12
101 INT161512 Ppig Negative_regulation of Positive_regulation of S100a8 1 0.02 0.23 1.12
102 INT212280 Vsnl1 Negative_regulation of Ltp 1 0.00 0.72 1.11
103 INT134870 Regulation of Binding of Calm3 and Nav1 1 0.17 0.42 1.1
104 INT136989 EGF Negative_regulation of Positive_regulation of KCNJ2 1 0.04 1.09 1.1
105 INT134869 Binding of Calm3 and Nav1 1 0.31 0.42 1.1
106 INT269191 Binding of Grin1 and Grin3a 2 0.32 1.05 1.09
107 INT298272 Runx1 Positive_regulation of Gene_expression of Ntrk3 1 0.52 0.88 1.09
108 INT187176 Binding of BSG and MMP1 1 0.09 1.18 1.08
109 INT317561 Binding of Grin1 and Oprm1 1 0.14 0.09 1.08
110 INT100678 IL4 Positive_regulation of STAT6 1 0.49 2.63 1.08
111 INT150794 ZNF398 Positive_regulation of Localization of THBS1 1 0.09 1.02 1.07
112 INT212281 Vsnl1 Regulation of Ltp 1 0.00 1.32 1.07
113 INT150784 ZNF398 Positive_regulation of Localization of THBS3 1 0.07 1.02 1.07
114 INT150789 THBS3 Negative_regulation of THBS1 1 0.18 1.01 1.06
115 INT317552 Binding of Calm3 and Car2 2 0.06 0.07 1.05
116 INT317531 Regulation of Binding of Grin1 and Mors1 1 0.08 0.06 1.05
117 INT150787 ZNF398 Positive_regulation of Gene_expression of SPARC 1 0.13 1.02 1.05
118 INT317534 Regulation of Binding of Camk2a and Grin1 1 0.20 0.06 1.05
119 INT97013 Negative_regulation of Binding of CALM3 and OPRM1 1 0.40 0 1.05
120 INT269199 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.03 0.56 1.05
121 INT97011 Binding of CALM3 and OPRM1 1 0.35 0 1.05
122 INT136988 EGF Negative_regulation of KCNJ2 1 0.04 1.09 1.04
123 INT317535 Binding of Grin1 and Mors1 1 0.07 0.06 1.04
124 INT118859 GNA14 Positive_regulation of STAT3 1 0.01 0.38 1.03
125 INT144069 Positive_regulation of TRPV1 Positive_regulation of Gene_expression of MMP1 1 0.43 1.35 1.03
126 INT269194 Ceacam3 Positive_regulation of Phosphorylation of Grin1 1 0.09 0.55 1.02
127 INT131889 gr Regulation of Gene_expression of Grin1 1 0.02 0 1.01
128 INT186161 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.11 1.05 1.01
129 INT30135 S100A9 Positive_regulation of REN 1 0.32 0.32 1
130 INT298298 Calca Negative_regulation of Gene_expression of Runx1 1 0.19 0.33 1
131 INT317532 Grin1 Regulation of Negative_regulation of Oprm1 1 0.18 0.07 1
132 INT298274 Gene_expression of Runx1 Negative_regulation of Calca 1 0.19 0.33 1
133 INT195668 Binding of F2 and THBD 7 0.08 5.67 0.98
134 INT156510 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.03 0.98 0.98
135 INT238091 Binding of GRIP1 and Mmp24 1 0.00 0 0.98
136 INT238092 Binding of SHBG and Mmp24 1 0.04 0 0.98
137 INT156508 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.22 0.98 0.98
138 INT353372 Dio1 Positive_regulation of Grin1 1 0.16 0 0.98
139 INT346204 Binding of S100A10 and TPPP 1 0.02 1.62 0.97
140 INT156380 Regulation of Binding of Grin1 and Dlg4 1 0.29 0.32 0.97
141 INT137919 Binding of Oprm1 and Stat3 1 0.30 0 0.97
142 INT296179 Pla2g2a Positive_regulation of Apcs 1 0.17 7.13 0.96
143 INT171264 TNF Positive_regulation of MMP1 2 0.10 2.05 0.95
144 INT133076 STAT6 Positive_regulation of OPRM1 1 0.38 0 0.95
145 INT253836 Cck Regulation of DST 1 0.03 0.42 0.95
146 INT166842 Binding of ANXA1 and Nfkb1 1 0.37 1.64 0.95
147 INT351311 Has1 Regulation of Gene_expression of MMP3 1 0.11 1.15 0.95
148 INT133071 STAT6 Positive_regulation of Gene_expression of GATA3 1 0.55 0 0.95
149 INT296283 Kcnip3 Regulation of Positive_regulation of Cysltr1 1 0.01 0.85 0.94
150 INT214411 DNAH8 Regulation of CAPN1 1 0.00 1.01 0.94
151 INT317559 Binding of Hint1 and Pla2g4a 1 0.01 0.06 0.94
152 INT231392 Enpp2 Positive_regulation of Gene_expression of Lpar1 2 0.38 2.19 0.93
153 INT250868 Fgf8 Positive_regulation of Gene_expression of Mmp3 1 0.15 1.73 0.93
154 INT144551 Binding of Lrp8 and Sepp1 1 0.55 1.73 0.93
155 INT103933 Cps1 Negative_regulation of Gene_expression of Cd69 1 0.03 0.25 0.93
156 INT103930 Cps1 Negative_regulation of Gene_expression of Il2ra 1 0.02 0.25 0.93
157 INT155259 RUNX1 Negative_regulation of Tnf 1 0.00 1.48 0.93
158 INT214409 ATP1A4 Regulation of CAPN1 1 0.01 1.01 0.93
159 INT72386 Egf Positive_regulation of Phosphorylation of Shc1 1 0.09 0.18 0.93
160 INT271635 Negative_regulation of GRIN1 Negative_regulation of Positive_regulation of Ltp 1 0.00 0.65 0.93
161 INT107001 F2 Positive_regulation of PAR1 4 0.05 2.15 0.92
162 INT75200 Umod Positive_regulation of Transcription of Psma4 1 0.02 1.04 0.92
163 INT151263 Jun Positive_regulation of S100a8 1 0.00 0.95 0.92
164 INT138602 Negative_regulation of BCL2L2 Positive_regulation of F2 1 0.00 0.67 0.92
165 INT243044 Mmp8 Regulation of Mmp9 1 0.05 1.45 0.91
166 INT138601 BCL2L2 Positive_regulation of F2 1 0.00 0.66 0.91
167 INT124742 ARSA Positive_regulation of Localization of CSF2 1 0.10 0.15 0.91
168 INT77330 Oprk1 Regulation of Localization of GRIN1 1 0.24 0 0.91
169 INT63488 Sptan1 Positive_regulation of Rtcd1 1 0.03 0.34 0.91
170 INT118288 EGF Positive_regulation of Phosphorylation of EGFR 9 0.54 3.85 0.9
171 INT185417 Binding of ALOX5 and PLA2G2A 4 0.16 3.13 0.9
172 INT133073 IL4 Positive_regulation of Phosphorylation of STAT6 1 0.39 0 0.9
173 INT220744 EGF Positive_regulation of Gene_expression of KRT20 1 0.01 1.26 0.9
174 INT121700 IL12RB1 Positive_regulation of Gene_expression of MMP1 1 0.06 0.22 0.9
175 INT52759 Oprd1 Regulation of Sptan1 1 0.03 0 0.9
176 INT121702 HRAS Negative_regulation of Positive_regulation of MMP1 1 0.06 0.2 0.9
177 INT121701 HRAS Negative_regulation of MMP1 1 0.06 0.2 0.89
178 INT121704 HRAS Negative_regulation of MMP3 1 0.06 0.19 0.89
179 INT52761 Dll1 Regulation of Sptan1 1 0.07 0 0.89
180 INT52762 Dll1 Regulation of Drd1a 1 0.10 0 0.89
181 INT284855 Binding of S100a10 and Nav1 4 0.21 0.99 0.88
182 INT134454 EGF Positive_regulation of EGFR 3 0.56 1.32 0.88
183 INT121699 HRAS Negative_regulation of Gene_expression of MMP1 1 0.06 0.19 0.88
184 INT134453 Negative_regulation of EGF Positive_regulation of EGFR 1 0.35 0.35 0.88
185 INT165540 NGF Positive_regulation of GRIN1 1 0.07 0.17 0.88
186 INT326455 Runx1 Positive_regulation of Gene_expression of Trpv1 1 0.45 0 0.88
187 INT315769 GRIN1 Negative_regulation of Plbd1 1 0.00 0.57 0.87
188 INT203148 Mif Positive_regulation of Gene_expression of S100a8 1 0.00 1.56 0.87
189 INT298289 Runx1 Negative_regulation of Ntrk2 1 0.60 1.09 0.87
190 INT52195 Sigmar1 Positive_regulation of Positive_regulation of Grin1 1 0.15 0 0.87
191 INT298295 Runx1 Negative_regulation of Gene_expression of Ntrk1 2 0.38 0.45 0.86
192 INT104126 STAT3 Regulation of Phospho1 1 0.00 0.06 0.86
193 INT167947 Binding of STAT1 and Oprm1 1 0.00 0 0.86
194 INT124743 ARSA Negative_regulation of PTGER2 1 0.03 0.15 0.85
195 INT194856 Positive_regulation of Adora2b Negative_regulation of Positive_regulation of Mmp13 1 0.01 0.73 0.85
196 INT190165 MMP12 Positive_regulation of MMP2 1 0.13 0.72 0.85
197 INT270218 P2rx3 Positive_regulation of Pla2g4a 1 0.34 0.63 0.85
198 INT167944 Binding of Oprm1 and Stat5a 1 0.00 0 0.85
199 INT260894 CRH Regulation of Localization of MMP3 1 0.21 0.36 0.85
200 INT124744 ARSA Negative_regulation of Gene_expression of PTGER2 1 0.03 0.15 0.85

Single Events

The table below shows the top 100 pain related interactions that have been reported for calcium ion binding. They are ordered first by their pain relevance and then by number of times they were reported in calcium ion binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61
2 INT90910 Phosphorylation of Grin1 150 0.82 68.23 139.24
3 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38
4 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02
5 INT133211 Gene_expression of Runx1 169 0.77 83.4 76.16
6 INT14049 Positive_regulation of GRIN1 102 0.70 48.31 71.06
7 INT90911 Positive_regulation of Phosphorylation of Grin1 62 0.70 27.45 59.26
8 INT7340 Regulation of Grin1 87 0.62 30.37 57.93
9 INT48232 Gene_expression of MMP1 245 0.78 96.31 57.72
10 INT4957 Negative_regulation of Grin1 87 0.59 24.51 53.21
11 INT57021 Positive_regulation of Gene_expression of Grin1 62 0.70 24.77 47.31
12 INT20492 Gene_expression of MMP12 89 0.76 81.36 46.12
13 INT29496 Gene_expression of MMP3 136 0.75 49.49 41.78
14 INT97596 Localization of S100a8 94 0.78 90.69 40.41
15 INT92517 Gene_expression of Grin1 105 0.78 29.53 39.43
16 INT11246 Binding of Grin1 65 0.48 14.53 36.93
17 INT52194 Positive_regulation of Grin1 83 0.69 25.09 34.76
18 INT47710 Negative_regulation of GRIN1 71 0.57 25.57 34.24
19 INT77310 Gene_expression of Aif1 89 0.78 50.49 33.68
20 INT57024 Regulation of Gene_expression of Grin1 32 0.62 9.77 32.6
21 INT67912 Gene_expression of GRIN1 75 0.77 28.99 29.28
22 INT106540 Negative_regulation of Phosphorylation of Grin1 15 0.58 9.32 29.13
23 INT8097 Gene_expression of EGF 122 0.77 75.94 28.47
24 INT80470 Negative_regulation of Gene_expression of Grin1 33 0.59 10.22 27.15
25 INT129956 Gene_expression of MMP13 145 0.72 60.48 26.98
26 INT9647 Gene_expression of PROC 163 0.65 89.76 26.75
27 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4
28 INT15777 Gene_expression of Pvalb 66 0.78 25.97 26.13
29 INT79979 Gene_expression of Ret 94 0.75 19.21 25.51
30 INT140193 Gene_expression of Mmp3 58 0.71 49.65 25.4
31 INT61664 Regulation of GRIN1 38 0.60 16.45 25.35
32 INT93717 Gene_expression of Mmp3 85 0.78 33.95 24.89
33 INT170313 Gene_expression of Mmp1a 50 0.65 38.53 21.36
34 INT11157 Binding of EGF 88 0.48 53.73 21.25
35 INT4535 Localization of PROC 106 0.73 76.24 21.1
36 INT116282 Gene_expression of Mmp13 83 0.75 45.4 20.18
37 INT93663 Positive_regulation of MMP1 72 0.67 33.38 19.86
38 INT113399 Positive_regulation of Pla2g4a 36 0.67 33.83 18.78
39 INT50420 Transcription of Grin1 30 0.71 13.21 18.28
40 INT187513 Positive_regulation of Pla2g4a 5 0.62 34.09 18.22
41 INT1060 Negative_regulation of Pla2g1b 50 0.57 22.91 18.12
42 INT23635 Positive_regulation of MMP12 31 0.59 28.19 17.95
43 INT107454 Positive_regulation of Stat3 43 0.68 19.63 17.69
44 INT63928 Negative_regulation of Grin1 51 0.56 11.81 17.57
45 INT150934 Gene_expression of GCH1 17 0.78 14.54 17.53
46 INT16624 Localization of Grin1 38 0.79 8.46 17.15
47 INT195831 Phosphorylation of Pla2g4a 15 0.74 34.43 17.14
48 INT1767 Positive_regulation of PROC 83 0.67 54.14 17
49 INT49379 Localization of MMP12 26 0.77 13.07 16.93
50 INT88356 Negative_regulation of Positive_regulation of Grin1 16 0.58 4.72 16.58
51 INT99898 Gene_expression of Mmp14 37 0.56 28.54 16.39
52 INT26314 Positive_regulation of MMP3 48 0.67 22.14 16.17
53 INT65659 Positive_regulation of STAT3 132 0.70 69.56 15.95
54 INT152730 Positive_regulation of S100a8 48 0.68 47.67 15.4
55 INT81486 Localization of MMP3 31 0.81 12.94 15.21
56 INT103210 Localization of MMP1 43 0.78 12.15 15.13
57 INT18513 Binding of GRIN1 32 0.47 9.44 15.08
58 INT12891 Negative_regulation of MMP3 41 0.58 17.99 15.06
59 INT74587 Gene_expression of MMP8 31 0.78 24.4 14.91
60 INT1284 Negative_regulation of Mmp13 20 0.57 36.21 14.91
61 INT129584 Positive_regulation of Stat3 97 0.68 87.07 14.86
62 INT92823 Positive_regulation of Gene_expression of MMP1 65 0.68 25.69 14.31
63 INT92513 Regulation of Grin1 26 0.59 9.12 13.94
64 INT7342 Positive_regulation of Positive_regulation of Grin1 18 0.50 9.22 13.76
65 INT50056 Positive_regulation of Dll1 13 0.67 3.16 13.7
66 INT190204 Positive_regulation of Gene_expression of MMP12 22 0.67 31.31 13.69
67 INT27739 Positive_regulation of EGF 49 0.70 28.31 13.68
68 INT152729 Negative_regulation of Gene_expression of S100a8 33 0.42 32.25 13.64
69 INT95427 Positive_regulation of Mmp3 39 0.70 15.28 13.36
70 INT13823 Gene_expression of Egf 97 0.78 39.99 12.99
71 INT123593 Gene_expression of Snca 58 0.78 35.76 12.87
72 INT119089 Regulation of Phosphorylation of Grin1 17 0.61 3.1 12.82
73 INT2673 Negative_regulation of PROC 93 0.57 50.34 12.79
74 INT107875 Phosphorylation of Stat3 49 0.80 13.18 12.66
75 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63
76 INT123779 Positive_regulation of MMP13 42 0.65 24.3 12.45
77 INT245517 Positive_regulation of Gene_expression of Runx1 49 0.69 17.7 12.38
78 INT56883 Positive_regulation of Dll1 8 0.49 3.49 12.25
79 INT112103 Binding of Grin1 28 0.48 4.21 12.08
80 INT133212 Negative_regulation of Runx1 21 0.58 11.16 11.89
81 INT21850 Gene_expression of Spna1 107 0.50 51.4 11.81
82 INT1190 Positive_regulation of F2 53 0.70 46.41 11.64
83 INT116347 Positive_regulation of Positive_regulation of GRIN1 12 0.49 3.63 11.44
84 INT3597 Positive_regulation of Pla2g1b 37 0.63 17.94 11.41
85 INT47702 Gene_expression of Sptan1 24 0.76 7.6 11.36
86 INT270238 Localization of Pla2g4a 1 0.72 17.99 11.35
87 INT96259 Positive_regulation of Plcg1 11 0.49 3.01 11.15
88 INT17826 Positive_regulation of Pla2g1b 39 0.70 11.35 10.97
89 INT6515 Gene_expression of BGLAP 110 0.75 45.13 10.81
90 INT4498 Gene_expression of F2 83 0.65 57.4 10.8
91 INT27651 Gene_expression of S100A12 45 0.76 52.25 10.51
92 INT6574 Negative_regulation of Pla2g1b 35 0.59 11.4 10.44
93 INT244490 Gene_expression of HSP90B1 4 0.33 41.16 10.37
94 INT139443 Positive_regulation of GCH1 9 0.69 8.2 10.14
95 INT133210 Positive_regulation of Runx1 33 0.69 18.25 10.12
96 INT127123 Positive_regulation of Snca 35 0.70 14.76 10.1
97 INT86813 Gene_expression of Pla2g4a 26 0.75 42.31 10.07
98 INT53590 Gene_expression of PRF1 33 0.58 23.46 10.02
99 INT107606 Negative_regulation of MMP1 38 0.42 11.94 10.01
100 INT61171 Gene_expression of S100A8 92 0.76 57.74 9.98
101 INT245538 Negative_regulation of Gene_expression of Runx1 20 0.58 11.68 9.97
102 INT95632 Positive_regulation of MMP8 26 0.70 10.06 9.96
103 INT6516 Positive_regulation of BGLAP 45 0.67 26.61 9.9
104 INT82829 Gene_expression of COMP 104 0.78 57 9.81
105 INT6065 Localization of GRIN1 15 0.74 3.15 9.81
106 INT2036 Localization of EGF 42 0.77 21.5 9.74
107 INT140191 Positive_regulation of Gene_expression of Mmp13 25 0.67 13.47 9.71
108 INT62544 Gene_expression of Anxa1 21 0.47 13.56 9.71
109 INT67101 Gene_expression of DST 47 0.54 25.92 9.59
110 INT183000 Transcription of KCNIP3 4 0.62 12.89 9.59
111 INT102987 Regulation of MMP3 23 0.60 9.35 9.54
112 INT114874 Gene_expression of Stat3 78 0.76 53.99 9.49
113 INT24328 Gene_expression of Egf 97 0.75 59.65 9.42
114 INT8249 Positive_regulation of Cubn 15 0.66 4.05 9.35
115 INT13893 Negative_regulation of Cubn 9 0.36 1.78 9.24
116 INT21846 Localization of Spna1 27 0.78 5.14 9.22
117 INT64346 Positive_regulation of S100B 95 0.70 63.11 9.17
118 INT48233 Negative_regulation of Gene_expression of MMP1 34 0.58 12.94 9.08
119 INT77490 Positive_regulation of Tnnc1 85 0.68 43.54 9.07
120 INT1168 Binding of PROC 62 0.38 44.15 9.04
121 INT32692 Positive_regulation of Aif1 33 0.35 13.29 9.03
122 INT45209 Positive_regulation of PLA2G2A 37 0.69 33.21 9.02
123 INT4534 Regulation of PROC 38 0.33 19.81 8.99
124 INT156874 Positive_regulation of Gene_expression of S100a8 26 0.49 32.8 8.99
125 INT56884 Gene_expression of Dll1 9 0.48 1.15 8.98
126 INT121987 Phosphorylation of Grin1 11 0.80 4.73 8.88
127 INT182995 Gene_expression of KCNIP3 19 0.69 13.28 8.81
128 INT56019 Gene_expression of Dll1 11 0.78 3.38 8.71
129 INT22771 Positive_regulation of Egf 44 0.70 16.45 8.64
130 INT129962 Positive_regulation of Gene_expression of MMP13 41 0.65 20.74 8.54
131 INT109005 Gene_expression of Proc 61 0.75 37.86 8.49
132 INT91370 Phosphorylation of STAT3 123 0.82 49.25 8.42
133 INT17250 Negative_regulation of BGLAP 35 0.57 21 8.26
134 INT114873 Phosphorylation of Stat3 63 0.82 30.19 8.23
135 INT4021 Positive_regulation of PLA2G1B 35 0.70 23.27 8.2
136 INT7813 Regulation of SRI 25 0.61 6.18 8.13
137 INT117642 Regulation of Gene_expression of Grin1 18 0.53 7.09 8.08
138 INT73544 Gene_expression of Grm7 34 0.64 31.28 8.04
139 INT2271 Gene_expression of F2 51 0.76 30.21 7.97
140 INT75684 Regulation of Aif1 32 0.47 8.03 7.89
141 INT113671 Negative_regulation of Mmp3 26 0.49 6.33 7.88
142 INT5164 Negative_regulation of Ldlr 83 0.58 55.01 7.87
143 INT110004 Gene_expression of Plcg1 7 0.41 2.61 7.87
144 INT165036 Gene_expression of S100a9 38 0.77 38.33 7.84
145 INT7125 Gene_expression of PLA2G2A 47 0.78 42.12 7.83
146 INT84894 Gene_expression of Calb2 45 0.73 24.65 7.81
147 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77
148 INT306287 Binding of TPPP 4 0.24 14.81 7.71
149 INT135113 Localization of Grin1 18 0.73 3.73 7.69
150 INT182976 Negative_regulation of KCNIP3 2 0.51 8.49 7.67
151 INT55859 Binding of Dll1 6 0.35 0 7.64
152 INT189230 Gene_expression of GSN 12 0.75 25.04 7.6
153 INT4022 Negative_regulation of PLA2G1B 30 0.59 10.41 7.58
154 INT24891 Gene_expression of SYP 55 0.75 45.76 7.53
155 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51
156 INT79502 Gene_expression of Pvalb 26 0.78 2.83 7.46
157 INT152347 Binding of GCH1 8 0.37 6.13 7.36
158 INT110705 Positive_regulation of Positive_regulation of Grin1 11 0.69 4.7 7.33
159 INT132246 Negative_regulation of S100a8 19 0.43 22 7.25
160 INT43727 Negative_regulation of Gene_expression of MMP3 16 0.40 4.81 7.18
161 INT58607 Negative_regulation of Dll1 9 0.43 1.89 7.06
162 INT10863 Positive_regulation of Ldlr 45 0.68 31.06 7.05
163 INT168381 Positive_regulation of Mmp3 24 0.58 19.12 7.03
164 INT717 Regulation of F2 29 0.61 17.46 6.99
165 INT110599 Gene_expression of Bglap 49 0.74 41.23 6.97
166 INT23782 Positive_regulation of Spna1 58 0.50 35.41 6.94
167 INT134864 Binding of Calm3 20 0.27 1.86 6.86
168 INT112986 Positive_regulation of S100b 19 0.70 17.61 6.86
169 INT79770 Regulation of Gene_expression of Aif1 13 0.45 5.28 6.82
170 INT2037 Negative_regulation of EGF 30 0.59 15.05 6.81
171 INT117299 Localization of S100b 19 0.78 1.58 6.8
172 INT1038 Negative_regulation of F2 26 0.58 15.12 6.75
173 INT46714 Positive_regulation of TNNC1 76 0.67 75.99 6.66
174 INT38644 Positive_regulation of DST 30 0.53 12.48 6.59
175 INT70287 Positive_regulation of Gene_expression of Dll1 6 0.70 3.58 6.55
176 INT13822 Localization of Egf 30 0.81 13.79 6.4
177 INT21613 Gene_expression of Pla2g1b 25 0.68 9.05 6.39
178 INT5254 Positive_regulation of Pla2g2a 22 0.68 10.42 6.37
179 INT155780 Gene_expression of Mmp8 19 0.77 15.85 6.33
180 INT129918 Positive_regulation of Phosphorylation of Stat3 17 0.63 5.42 6.28
181 INT168383 Positive_regulation of Mmp13 27 0.67 17.9 6.27
182 INT169596 Transcription of Runx1 12 0.71 5.55 6.27
183 INT245515 Regulation of Runx1 14 0.61 5.07 6.22
184 INT11826 Positive_regulation of LDLR 62 0.62 45.09 6.21
185 INT82828 Positive_regulation of COMP 45 0.61 35.12 6.2
186 INT23465 Gene_expression of S100b 31 0.76 15.09 6.2
187 INT95607 Regulation of MMP1 19 0.60 7.86 6.18
188 INT153959 Phosphorylation of GRIN1 8 0.80 4.07 6.18
189 INT163776 Regulation of GCH1 7 0.27 4.58 6.16
190 INT133971 Binding of Kcnip3 4 0.42 5.54 6.12
191 INT140503 Negative_regulation of Gene_expression of Mmp3 7 0.44 5.93 6.08
192 INT14238 Positive_regulation of Cd69 19 0.60 17.75 6.07
193 INT117621 Positive_regulation of HSPA5 17 0.59 13.26 6.06
194 INT14516 Positive_regulation of CRTAC1 14 0.37 4.6 6.01
195 INT141751 Localization of Syt1 21 0.78 11.19 5.98
196 INT93684 Gene_expression of STAT3 66 0.78 34.42 5.94
197 INT254400 Negative_regulation of GSN 22 0.57 18.15 5.89
198 INT97018 Binding of CALM3 7 0.43 0.13 5.82
199 INT69929 Gene_expression of S100a9 11 0.77 16.12 5.79
200 INT60032 Negative_regulation of Pla2g2a 29 0.58 12.42 5.75
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