GO:0005518

Name collagen binding Categary Function Go Slim No Go Link GO:0005518

Unique Molecular Interactions 581 Total Molecular Interactions 814 Total Single Events 7039 Pain Genes Associated 60

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for collagen binding. They are ordered first by their pain relevance and then by number of times they were reported for collagen binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT113550	Binding of FN1 and VTN	6	0.30	5.24	1.91
2	INT205152	Binding of CD44 and MMP9	23	0.35	17.13	1.85
3	INT100771	Binding of Itga1 and Vcam1	3	0.11	3.91	1.79
4	INT147108	TGFB1 Positive_regulation of Gene_expression of FN1	4	0.47	1.01	1.63
5	INT326509	Binding of ACE and VWF	1	0.05	2.07	1.59
6	INT168609	Binding of Itgb1 and Mmp9	1	0.02	0.41	1.58
7	INT54601	Binding of Mtor and Ache	1	0.20	0.8	1.58
8	INT201950	IFNA1 Positive_regulation of Binding of DPP4	1	0.12	2.17	1.47
9	INT201946	IFNA1 Positive_regulation of DPP4	1	0.17	2.16	1.46
10	INT225019	PDGFB Positive_regulation of Gene_expression of Cxcl1	1	0.27	0.54	1.4
11	INT131949	ANTXR1 Positive_regulation of NAV1	1	0.03	0.23	1.38
12	INT158762	Binding of Vwf and Mthfr	1	0.05	1.85	1.37
13	INT178986	Binding of MMP9 and TIMP1	4	0.47	2.58	1.33
14	INT201942	DPP4 Negative_regulation of CXCL10	1	0.33	0.9	1.3
15	INT271602	Binding of Pdgfa and Pdgfrl	1	0.02	0.86	1.25
16	INT202042	CAMK2N2 Negative_regulation of MMP9	1	0.01	0.73	1.25
17	INT187172	RPS3AP9 Negative_regulation of MMP9	1	0.00	0.89	1.2
18	INT150787	ZNF398 Positive_regulation of Gene_expression of SPARC	1	0.13	1.02	1.05
19	INT106706	POMC Negative_regulation of Binding of FN1	1	0.19	0.79	1.02
20	INT187111	TIMP2 Regulation of MMP9	1	0.23	1.47	0.97
21	INT266659	Binding of MMP9 and MOCS1	1	0.01	1.71	0.94
22	INT222979	Negative_regulation of Binding of COL1A1 and FN1	1	0.01	1.64	0.93
23	INT222978	Binding of COL1A1 and FN1	1	0.01	1.64	0.92
24	INT271601	Pdgfa Positive_regulation of Pdgfrl	1	0.03	0.83	0.91
25	INT251704	Ache Regulation of Gene_expression of Acot1	1	0.08	1.68	0.87
26	INT340437	Binding of SERPINH1 and HLA-DRB4	1	0.00	2.26	0.84
27	INT107698	FN1 Positive_regulation of Gene_expression of CPOX	1	0.13	0.26	0.84
28	INT113250	Olr1259 Negative_regulation of Ache	1	0.01	0.38	0.83
29	INT196525	Binding of MMP2 and MMP9	2	0.32	2.49	0.78
30	INT84466	DPP4 Regulation of Localization of Naga	1	0.00	0.87	0.78
31	INT113546	Binding of FN1 and ITGA3	1	0.03	2.12	0.77
32	INT46246	Tpsg1 Regulation of Ache	1	0.15	0.06	0.76
33	INT46247	Tpsg1 Regulation of Binding of Ache	1	0.15	0.06	0.76
34	INT88921	Positive_regulation of CYP2D6 Negative_regulation of ANTXR1	1	0.00	0.8	0.75
35	INT88922	CYP2D6 Negative_regulation of ANTXR1	1	0.00	0.8	0.75
36	INT201947	IFNA1 Positive_regulation of Gene_expression of DPP4	1	0.11	1.09	0.74
37	INT295711	MMP9 Positive_regulation of Localization of VEGFA	1	0.06	0.29	0.74
38	INT4917	Binding of Pcolce and Tac2	1	0.03	0	0.74
39	INT170992	Binding of FN1 and MMRN1	3	0.01	2.13	0.73
40	INT18447	Binding of Ache and Chat	2	0.33	0.33	0.73
41	INT224580	Gene_expression of IL18 Positive_regulation of SERPINH1	1	0.00	1.34	0.7
42	INT295720	PTGER2 Regulation of MMP9	1	0.01	0.53	0.7
43	INT102863	Prkaca Regulation of Srgn	1	0.50	0.05	0.64
44	INT302469	F2 Positive_regulation of Gene_expression of MMP9	1	0.01	1.82	0.62
45	INT282286	Akt1 Positive_regulation of Pak1	1	0.15	0.24	0.61
46	INT295724	CXCL12 Positive_regulation of MMP9	1	0.02	0.32	0.6
47	INT295721	CSF2 Positive_regulation of MMP9	1	0.06	0.32	0.6
48	INT202038	MMP9 Positive_regulation of IL8	1	0.05	0.29	0.59
49	INT175626	TIMP1 Positive_regulation of Gene_expression of MMP9	1	0.03	0.72	0.57
50	INT129271	Binding of ANTXR1 and Efs	1	0.00	0	0.56
51	INT265463	CSPG4 Negative_regulation of Gene_expression of IL6	1	0.06	1.6	0.56
52	INT173556	TIMP1 Negative_regulation of MMP9	1	0.02	0	0.56
53	INT175623	TIMP1 Positive_regulation of MMP9	1	0.03	0.71	0.56
54	INT137897	Binding of SERPINH1 and IL36B	1	0.00	0.64	0.55
55	INT91428	CD44 Positive_regulation of Binding of MMRN1	1	0.24	0.85	0.55
56	INT343913	Binding of FOS and Smad3	1	0.19	0.92	0.54
57	INT150800	THBS3 Negative_regulation of SPARC	1	0.23	0.51	0.53
58	INT196524	Binding of MMP1 and MMP9	1	0.31	0.74	0.51
59	INT196519	Positive_regulation of Binding of MMP1 and MMP9	1	0.42	0.74	0.51
60	INT187116	TIMP2 Negative_regulation of MMP9	1	0.36	1.37	0.5
61	INT36143	Binding of SERPINH1 and HLA-B	1	0.00	0.66	0.49
62	INT175326	SERPINH1 Regulation of Pnlip	1	0.00	0.53	0.49
63	INT127664	Negative_regulation of PDE4A Negative_regulation of MMP9	1	0.37	0.76	0.48
64	INT127665	Negative_regulation of PDE4A Negative_regulation of Transcription of MMP9	1	0.37	0.76	0.48
65	INT352892	Binding of CAV1 and ITGA2	1	0.20	1.61	0.47
66	INT147444	PDGFA Positive_regulation of Gene_expression of Ros1	2	0.00	0.95	0.46
67	INT187099	Binding of Cd4 and Itga1	1	0.00	1.09	0.46
68	INT168445	Positive_regulation of C2 Positive_regulation of Positive_regulation of Dcn	1	0.14	0.66	0.46
69	INT117776	Binding of Ptk2 and Regulation of Phosphorylation of Ddr1	1	0.10	0.17	0.46
70	INT299041	SPARC Regulation of Gene_expression of NPEPPS	1	0.01	0.83	0.42
71	INT226070	Binding of CRP and MMP9	1	0.51	1.13	0.42
72	INT107701	Negative_regulation of FN1 Positive_regulation of CPOX	1	0.11	0.13	0.42
73	INT303857	DDR1 Positive_regulation of IL8	1	0.05	1.5	0.42
74	INT303858	DDR1 Positive_regulation of CXCR2	1	0.11	1.5	0.42
75	INT201943	Regulation of Binding of DPP4 and CXCL10	1	0.20	0.58	0.42
76	INT248239	Binding of FN1 and SDC3	1	0.00	0.77	0.42
77	INT299040	Binding of COL7A1 and SPARC	1	0.02	0.7	0.42
78	INT107696	FN1 Positive_regulation of CPOX	1	0.12	0.13	0.41
79	INT248236	Binding of FN1 and SDC1	1	0.00	0.76	0.41
80	INT120894	Binding of Gp1ba and Vwf	1	0.00	1.38	0.4
81	INT346150	Binding of ADM and FN1	1	0.10	0.93	0.39
82	INT265465	CSPG4 Negative_regulation of Gene_expression of IL8	1	0.07	0.98	0.39
83	INT226072	Binding of MMP9 and SHBG	1	0.15	1.02	0.39
84	INT346135	Positive_regulation of Binding of ADM and FN1	1	0.13	0.93	0.39
85	INT201948	Binding of DPP4 and CXCL10	1	0.27	0.54	0.39
86	INT305407	Binding of ST8SIA2 and ANTXR1	1	0.00	0.09	0.38
87	INT291616	Cby1 Positive_regulation of Gene_expression of Smad7	1	0.00	0.79	0.38
88	INT305405	Binding of KCNMA1 and ANTXR1	1	0.00	0.09	0.38
89	INT200469	Binding of COL7A1 and COMP	1	0.04	0.91	0.38
90	INT166792	Binding of CD44 and HRAS	3	0.12	1.49	0.37
91	INT113560	Negative_regulation of Binding of FN1 and PLAUR	1	0.26	0.87	0.37
92	INT113556	Binding of FN1 and PLAUR	1	0.22	0.81	0.37
93	INT151698	Binding of RNF130 and Vwf	1	0.04	0.29	0.37
94	INT113555	Negative_regulation of Binding of FN1 and VTN	1	0.23	0.87	0.37
95	INT172023	Binding of FN1 and PRTN3	1	0.00	1.05	0.37
96	INT133307	Binding of CD44 and SPP1	5	0.26	2.6	0.35
97	INT302466	Positive_regulation of F2 Positive_regulation of Gene_expression of MMP9	1	0.01	1.1	0.35
98	INT254393	Binding of FN1 and GSN	1	0.01	1.08	0.34
99	INT323352	Binding of F8 and VWF	5	0.08	2.22	0.33
100	INT51630	Binding of ACHE and OPRM1	1	0.11	0	0.33
101	INT333993	Binding of Vcam1 and Vwf	1	0.00	1.32	0.33
102	INT110350	Positive_regulation of Arigg3 Positive_regulation of Positive_regulation of Dpp4	1	0.01	0	0.33
103	INT322045	Gp6 Positive_regulation of Gene_expression of Selp	1	0.04	0.15	0.33
104	INT295755	Fgf2 Regulation of MMP9	1	0.07	0.99	0.33
105	INT51628	Binding of ACHE and DRD3	1	0.15	0	0.33
106	INT295717	VEGFA Regulation of MMP9	1	0.01	0.98	0.33
107	INT340616	COL4A4 Regulation of MMP9	1	0.12	0.95	0.32
108	INT44127	Agt Negative_regulation of DSPP	1	0.02	0	0.32
109	INT311228	DPP4 Negative_regulation of Localization of GLP1R	1	0.31	1.25	0.32
110	INT257739	SAGE1 Positive_regulation of DDR1	1	0.00	0.91	0.31
111	INT187102	Negative_regulation of Binding of MMP9 and TIMP2	1	0.36	0.69	0.3
112	INT118300	Vwf Positive_regulation of Crp	1	0.00	0.87	0.3
113	INT213062	PTGS1 Regulation of Gene_expression of MMP9	1	0.04	0.25	0.3
114	INT187106	Binding of MMP9 and TIMP2	1	0.30	0.69	0.3
115	INT225021	PDGFB Positive_regulation of Ccl21	1	0.10	0.07	0.3
116	INT333398	CFD Negative_regulation of Gene_expression of Pdgfa	1	0.02	0.64	0.3
117	INT187113	Binding of IGHG3 and MMP9	1	0.01	0.63	0.3
118	INT225026	PDGFB Positive_regulation of Gene_expression of Ccl21	1	0.10	0.07	0.3
119	INT260896	CRH Positive_regulation of Localization of MMP9	1	0.15	0.15	0.3
120	INT179844	Nid1 Regulation of Negative_regulation of Il11	1	0.19	0	0.29
121	INT202313	Gene_expression of PDGFB Positive_regulation of Positive_regulation of Pdgfrb	1	0.14	1	0.29
122	INT187105	TIMP2 Negative_regulation of Positive_regulation of MMP9	1	0.36	0.36	0.29
123	INT57498	Vwf Positive_regulation of F8	1	0.00	0.36	0.29
124	INT202314	Gene_expression of PDGFB Positive_regulation of Phosphorylation of Pdgfrb	1	0.14	1	0.29
125	INT132426	Binding of F13A1 and Vwf	1	0.01	1.86	0.28
126	INT64892	ANTXR1 Regulation of Gtpbp4	1	0.00	0.47	0.28
127	INT355734	Pdgfb Regulation of Bdnf	1	0.22	1.5	0.27
128	INT224457	TNF Positive_regulation of Pdgfa	1	0.34	1.22	0.27
129	INT269313	Binding of Ptafr and Gp6	1	0.00	0.48	0.26
130	INT20547	IL1B Positive_regulation of Gene_expression of FN1	1	0.29	0.06	0.26
131	INT20549	IL1B Positive_regulation of FN1	1	0.19	0.06	0.26
132	INT302468	INCENP Positive_regulation of Gene_expression of MMP9	1	0.01	0.72	0.26
133	INT160225	Acot1 Negative_regulation of Ache	1	0.28	2.18	0.25
134	INT332242	Binding of Egf and Pdgfa	1	0.07	0.97	0.25
135	INT20548	IL1B Regulation of Gene_expression of FN1	1	0.19	0.07	0.25
136	INT23626	Ache Regulation of Mir343	1	0.17	0	0.24
137	INT208728	Positive_regulation of Dcn Positive_regulation of Cysltr1	1	0.02	0.3	0.24
138	INT172022	Binding of F13A1 and FN1	1	0.00	1.33	0.24
139	INT178077	EDN1 Positive_regulation of MMP9	1	0.06	0.88	0.24
140	INT208732	Dcn Positive_regulation of Cysltr1	1	0.02	0.29	0.24
141	INT205155	Negative_regulation of Binding of CD44 and MMP9	1	0.32	1.98	0.23
142	INT213061	PTGER2 Regulation of Gene_expression of MMP9	1	0.03	0.25	0.23
143	INT225117	Foxm1 Regulation of Gene_expression of FN1	1	0.01	0.4	0.22
144	INT187117	Negative_regulation of TIMP2 Negative_regulation of MMP9	1	0.36	0.6	0.22
145	INT321980	Negative_regulation of Dpp4 Negative_regulation of Positive_regulation of Ins1	1	0.16	0.81	0.22
146	INT193035	Positive_regulation of PDGFA Positive_regulation of EGF	1	0.05	0.53	0.21
147	INT193025	PDGFA Positive_regulation of EGF	1	0.05	0.53	0.21
148	INT193036	EGF Positive_regulation of PDGFA	1	0.05	0.53	0.21
149	INT193032	Positive_regulation of EGF Positive_regulation of PDGFA	1	0.05	0.53	0.21
150	INT166791	CD44 Positive_regulation of Gene_expression of PTGER1	1	0.05	0.15	0.2
151	INT137569	Comp Negative_regulation of Positive_regulation of Prl	1	0.23	0	0.2
152	INT102743	Binding of SEPT5 and Vwf	1	0.01	0.35	0.2
153	INT279107	Binding of COMP and MATN3	1	0.41	1.43	0.2
154	INT189553	DCN Negative_regulation of Transcription of VEGFA	1	0.06	0.78	0.2
155	INT137568	Comp Negative_regulation of Regulation of Prl	1	0.17	0	0.2
156	INT325470	MMP3 Positive_regulation of MMP9	1	0.17	0.9	0.2
157	INT255516	Binding of COL5A2 and GP6	1	0.01	1.17	0.2
158	INT137570	Comp Negative_regulation of Prl	1	0.17	0	0.2
159	INT166787	CD44 Negative_regulation of Gene_expression of PTGER1	1	0.04	0.15	0.2
160	INT312708	DPP8 Positive_regulation of DPP4	1	0.24	0.54	0.19
161	INT312706	DPP9 Positive_regulation of DPP4	1	0.26	0.54	0.19
162	INT335298	IRF6 Positive_regulation of MMP9	1	0.01	0.21	0.19
163	INT332245	Pdgfa Positive_regulation of Stat6	1	0.07	1.22	0.19
164	INT251665	LRP5 Negative_regulation of Ache	1	0.31	0.39	0.19
165	INT355733	Pdgfb Regulation of Transcription of Bdnf	1	0.10	0.86	0.19
166	INT50153	Positive_regulation of Bcar3 Positive_regulation of Gene_expression of Dcn	1	0.01	0.06	0.19
167	INT226071	Binding of HSD11B1 and MMP9	1	0.09	0.47	0.19
168	INT192333	PDGFA Positive_regulation of Gene_expression of FN1	2	0.11	1.26	0.18
169	INT280052	Negative_regulation of Dpp4 Positive_regulation of Zglp1	1	0.03	0.72	0.18
170	INT99006	Regulation of Binding of Selp and Itga1	1	0.06	1.36	0.18
171	INT99012	Binding of Selp and Itga1	1	0.05	1.36	0.18
172	INT284450	Edn1 Positive_regulation of Gene_expression of MMP9	1	0.01	0.3	0.18
173	INT180560	Binding of COMP and CYP27A1	1	0.12	0.47	0.18
174	INT333449	Binding of SMAD2 and SMAD4	1	0.23	0	0.17
175	INT210795	Ihh Negative_regulation of Itgb1	1	0.30	0	0.17
176	INT142332	Binding of SERPINH1 and TNNI3	1	0.03	1.05	0.17
177	INT169117	PLAU Regulation of Gene_expression of MMP9	1	0.47	0.49	0.17
178	INT355732	Pdgfb Negative_regulation of Bdnf	1	0.13	0.87	0.17
179	INT311226	DPP4 Negative_regulation of GLP1R	1	0.31	0.65	0.16
180	INT301907	Binding of THBD and VWF	1	0.02	1.71	0.16
181	INT202312	PDGFB Positive_regulation of Gene_expression of Col7a1	1	0.01	0.7	0.16
182	INT47357	Binding of FN1 and ANGPTL5	1	0.20	0.48	0.16
183	INT202311	PDGFB Positive_regulation of Gene_expression of Fn1	1	0.02	0.7	0.16
184	INT56010	Binding of FN1 and FKBPL	1	0.00	0.54	0.15
185	INT298717	Fgf2 Positive_regulation of Gene_expression of PDGFA	1	0.01	0.23	0.15
186	INT298716	Ngf Positive_regulation of Gene_expression of PDGFA	1	0.01	0.22	0.15
187	INT56008	Binding of FN1 and PTDSS1	1	0.05	0.55	0.15
188	INT180566	Binding of COMP and DMD	1	0.02	0.72	0.15
189	INT70090	TGM1 Positive_regulation of Binding of Ache	1	0.03	0.59	0.15
190	INT238331	PDGFA Regulation of Gene_expression of GOPC	1	0.04	0	0.14
191	INT58187	ITGA1 Positive_regulation of Itga3	1	0.01	1.47	0.14
192	INT238330	Binding of PDGFA and Regulation of Gene_expression of GOPC	1	0.06	0	0.14
193	INT332254	Pdgfa Positive_regulation of Stat3	1	0.02	0.52	0.14
194	INT327879	Binding of Itgb1 and Postn	1	0.02	1.05	0.14
195	INT141224	Ache Regulation of Acot1	1	0.09	0.29	0.14
196	INT27393	Tha1 Negative_regulation of Ache	1	0.15	0.24	0.14
197	INT238333	Binding of PDGFA and Regulation of Gene_expression of ADAMTS1	1	0.06	0	0.14
198	INT286900	Binding of HBM and PDGFA	1	0.04	1.08	0.14
199	INT155687	PDGFA Positive_regulation of Phosphorylation of FBRS	1	0.01	0.43	0.14
200	INT332256	Pdgfa Positive_regulation of SOAT1	1	0.01	0.51	0.14

Single Events

The table below shows the top 100 pain related interactions that have been reported for collagen binding. They are ordered first by their pain relevance and then by number of times they were reported in collagen binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT1080	Negative_regulation of Ache	343	0.59	108.51	72.4
2	INT73048	Gene_expression of MMP9	268	0.77	159.75	57.81
3	INT99610	Localization of MMP9	126	0.79	48.46	32.67
4	INT1079	Positive_regulation of Ache	104	0.70	23.52	30.28
5	INT2569	Gene_expression of Ache	120	0.78	26.29	26.89
6	INT73047	Positive_regulation of MMP9	133	0.68	73.22	26.42
7	INT276	Regulation of Ache	83	0.62	16.75	25.99
8	INT14737	Gene_expression of FN1	117	0.78	78.74	18.99
9	INT9900	Positive_regulation of Vwf	80	0.69	51.85	18.13
10	INT84464	Gene_expression of DPP4	101	0.78	56.15	17.53
11	INT19071	Localization of Ache	66	0.81	5.1	16.27
12	INT1752	Negative_regulation of Ache	109	0.59	42.05	15.73
13	INT103245	Positive_regulation of Gene_expression of MMP9	64	0.68	36.86	15.7
14	INT96775	Gene_expression of Pdgfa	42	0.54	29.78	15.46
15	INT63361	Gene_expression of CD44	126	0.77	71.58	12.96
16	INT93715	Negative_regulation of MMP9	69	0.55	36.05	11.73
17	INT89282	Regulation of MMP9	39	0.60	25.45	10.34
18	INT1252	Binding of Ache	46	0.48	9.94	10.25
19	INT82829	Gene_expression of COMP	104	0.78	57	9.81
20	INT126031	Negative_regulation of Gene_expression of MMP9	40	0.57	22.71	9.79
21	INT132036	Negative_regulation of DPP4	126	0.59	63.24	9.51
22	INT9899	Gene_expression of Vwf	91	0.74	45.06	9.13
23	INT27551	Gene_expression of SERPINH1	45	0.62	42.87	9.04
24	INT187190	Positive_regulation of Localization of MMP9	27	0.68	8.1	8.93
25	INT2597	Negative_regulation of ACHE	82	0.59	46.36	8.62
26	INT621	Positive_regulation of SERPINH1	19	0.57	21.52	8.44
27	INT70896	Gene_expression of PDGFB	48	0.65	33.55	8.39
28	INT60034	Positive_regulation of VWF	40	0.68	30.42	8.15
29	INT81378	Negative_regulation of Dpp4	18	0.59	7.87	7.42
30	INT14732	Positive_regulation of FN1	46	0.69	31.17	7.33
31	INT67822	Binding of SERPINH1	17	0.36	19.05	7.24
32	INT95117	Gene_expression of PDGFA	71	0.71	51.17	6.9
33	INT82828	Positive_regulation of COMP	45	0.61	35.12	6.2
34	INT55655	Gene_expression of DCN	17	0.75	7.98	5.98
35	INT131378	Negative_regulation of FN1	20	0.35	33.98	5.85
36	INT13170	Gene_expression of Comp	25	0.74	8.68	5.62
37	INT32458	Gene_expression of VWF	57	0.78	28.97	5.56
38	INT99606	Negative_regulation of Localization of MMP9	23	0.57	7.15	5.47
39	INT96778	Positive_regulation of Pdgfa	22	0.46	12.7	5.31
40	INT19072	Regulation of Gene_expression of Ache	14	0.62	2.74	5.29
41	INT10888	Binding of Vwf	32	0.46	22.87	5.21
42	INT20059	Protein_catabolism of Ache	15	0.98	3.73	4.87
43	INT185877	Negative_regulation of Gene_expression of DCN	3	0.33	2.37	4.85
44	INT94453	Gene_expression of ITGB1	50	0.75	18.41	4.72
45	INT74447	Gene_expression of Vwf	39	0.76	21.96	4.66
46	INT102855	Negative_regulation of Srgn	8	0.57	0.91	4.63
47	INT1753	Gene_expression of Ache	38	0.78	15.31	4.58
48	INT46121	Negative_regulation of SERPINH1	14	0.38	10.84	4.41
49	INT74531	Regulation of PDGFB	14	0.26	7.57	4.38
50	INT57273	Positive_regulation of Gene_expression of FN1	26	0.47	17.83	4.2
51	INT11946	Transcription of Ache	18	0.69	2.62	4.13
52	INT110348	Negative_regulation of Dpp4	28	0.46	22.39	4.12
53	INT99608	Transcription of MMP9	18	0.65	9.67	4.11
54	INT96776	Positive_regulation of Gene_expression of Pdgfa	8	0.40	7.79	3.93
55	INT133312	Binding of MMP9	25	0.42	16.79	3.83
56	INT20925	Binding of ANTXR1	15	0.01	4.2	3.8
57	INT120072	Gene_expression of Smad7	38	0.74	20.87	3.69
58	INT10146	Negative_regulation of Vwf	27	0.40	17.11	3.69
59	INT13451	Positive_regulation of DPP4	23	0.68	9.33	3.62
60	INT8778	Regulation of Ache	17	0.62	3.7	3.57
61	INT162258	Negative_regulation of Gene_expression of COMP	35	0.58	19.14	3.55
62	INT70897	Positive_regulation of Gene_expression of PDGFB	15	0.57	13.04	3.52
63	INT96777	Localization of Pdgfa	12	0.79	5.86	3.52
64	INT130351	Positive_regulation of Vwf	18	0.59	5.99	3.48
65	INT70895	Localization of PDGFB	20	0.52	8.98	3.4
66	INT201959	Positive_regulation of Gene_expression of DPP4	13	0.53	6.24	3.4
67	INT118095	Regulation of COMP	7	0.43	9.69	3.33
68	INT28009	Positive_regulation of Gene_expression of Ache	15	0.70	5.46	3.26
69	INT22375	Localization of PDGFA	21	0.75	15.46	3.25
70	INT70885	Gene_expression of Pdgfb	48	0.67	42.27	3.19
71	INT279122	Regulation of Gene_expression of COMP	3	0.39	8.82	3.19
72	INT8777	Positive_regulation of Ache	25	0.68	7.77	3.18
73	INT61500	Binding of FN1	39	0.48	27.33	3.13
74	INT55409	Localization of VWF	17	0.80	8.99	3.06
75	INT19293	Protein_catabolism of FN1	7	0.95	5.15	2.97
76	INT200470	Positive_regulation of Gene_expression of COMP	13	0.69	13.73	2.93
77	INT201952	Binding of DPP4	11	0.37	8.81	2.91
78	INT22069	Positive_regulation of Localization of Ache	9	0.70	0.61	2.9
79	INT322473	Localization of DCN	1	0.03	0.76	2.9
80	INT10893	Binding of VWF	27	0.47	25.02	2.82
81	INT271599	Phosphorylation of Pdgfa	1	0.11	2.55	2.81
82	INT73836	Regulation of Comp	4	0.19	4.2	2.79
83	INT10516	Localization of Vwf	30	0.79	7.54	2.77
84	INT53755	Positive_regulation of Dcn	8	0.43	2.91	2.74
85	INT143952	Regulation of Gene_expression of MMP9	14	0.53	10.16	2.73
86	INT172963	Negative_regulation of Pdgfa	11	0.21	12.94	2.64
87	INT11892	Gene_expression of ACHE	10	0.68	1.32	2.63
88	INT12619	Positive_regulation of ANTXR1	7	0.49	3.17	2.61
89	INT74527	Positive_regulation of PDGFB	14	0.38	13.31	2.54
90	INT102856	Positive_regulation of Srgn	7	0.61	1.27	2.54
91	INT91429	Binding of CD44	34	0.41	17.67	2.51
92	INT81377	Gene_expression of Dpp4	8	0.71	5.15	2.51
93	INT15540	Positive_regulation of PDGFA	24	0.47	19.01	2.5
94	INT94010	Positive_regulation of Localization of VWF	9	0.70	4.23	2.5
95	INT61805	Positive_regulation of Dpp4	4	0.44	0.41	2.49
96	INT183810	Positive_regulation of Positive_regulation of MMP9	9	0.52	4.15	2.46
97	INT223080	Binding of Pdgfa	8	0.18	7.21	2.44
98	INT192337	Positive_regulation of DDR1	11	0.41	10.34	2.38
99	INT27338	Regulation of ACHE	6	0.62	1.25	2.38
100	INT68087	Regulation of Vwf	9	0.39	8.06	2.36
101	INT71273	Positive_regulation of Comp	8	0.42	3.8	2.32
102	INT84465	Localization of DPP4	8	0.75	7.28	2.29
103	INT8052	Negative_regulation of COMP	46	0.58	13.73	2.22
104	INT14890	Localization of ACHE	5	0.80	0.47	2.21
105	INT184305	Gene_expression of Comp	53	0.77	31.66	2.2
106	INT289775	Negative_regulation of Comp	4	0.41	5.69	2.2
107	INT2570	Negative_regulation of Gene_expression of Ache	13	0.43	2.88	2.18
108	INT27437	Negative_regulation of Comp	5	0.24	2.8	2.15
109	INT15090	Regulation of ANTXR1	4	0.31	2.4	2.05
110	INT103244	Protein_catabolism of MMP9	12	0.72	11.81	2.01
111	INT173851	Localization of FN1	20	0.76	13.95	1.97
112	INT57272	Negative_regulation of Gene_expression of FN1	16	0.43	11.42	1.93
113	INT47062	Gene_expression of ANTXR1	10	0.66	4.63	1.93
114	INT107178	Gene_expression of Smad4	12	0.65	9.85	1.92
115	INT38201	Negative_regulation of Localization of Ache	8	0.59	2.35	1.82
116	INT142477	Gene_expression of GP6	12	0.76	12.53	1.79
117	INT222997	Positive_regulation of Localization of FN1	4	0.14	4.26	1.78
118	INT91430	Positive_regulation of CD44	25	0.69	15.43	1.76
119	INT174924	Gene_expression of Smad7	6	0.41	3.59	1.76
120	INT211200	Regulation of SERPINH1	2	0.03	3.8	1.75
121	INT38574	Binding of Ache	9	0.47	3.64	1.74
122	INT168602	Negative_regulation of Itgb1	3	0.21	1.29	1.73
123	INT174923	Positive_regulation of Gene_expression of Smad7	3	0.37	2.3	1.73
124	INT8757	Binding of ACHE	10	0.48	5.84	1.72
125	INT6598	Gene_expression of ITGA2	9	0.46	4.88	1.72
126	INT37954	Negative_regulation of Dcn	6	0.41	0.62	1.72
127	INT102857	Phosphorylation of Srgn	1	0.72	0.26	1.71
128	INT2847	Positive_regulation of Negative_regulation of Ache	8	0.49	1.09	1.65
129	INT14891	Positive_regulation of ACHE	10	0.70	5.37	1.64
130	INT322472	Negative_regulation of Localization of DCN	1	0.02	0.47	1.64
131	INT93744	Binding of Dpp4	4	0.48	0.91	1.61
132	INT97318	Gene_expression of SPARC	11	0.67	5.07	1.59
133	INT89849	Regulation of Srgn	6	0.30	0.93	1.59
134	INT186724	Negative_regulation of Transcription of MMP9	5	0.37	1.59	1.57
135	INT103767	Phosphorylation of DDR1	6	0.20	4.67	1.56
136	INT166085	Binding of Gp6	11	0.42	3.09	1.55
137	INT295688	Positive_regulation of Regulation of MMP9	1	0.14	0.67	1.51
138	INT74528	Negative_regulation of PDGFB	11	0.40	10.34	1.48
139	INT74530	Transcription of PDGFB	7	0.65	4.56	1.47
140	INT57973	Positive_regulation of ITGB1	5	0.67	1.23	1.44
141	INT118097	Localization of COMP	18	0.70	9.99	1.42
142	INT44529	Positive_regulation of Pdgfb	11	0.43	7.98	1.36
143	INT55476	Negative_regulation of ITGA2	8	0.55	3.55	1.33
144	INT84463	Regulation of Gene_expression of DPP4	5	0.39	4.81	1.33
145	INT102852	Negative_regulation of Phosphorylation of Srgn	1	0.52	0.17	1.32
146	INT247903	Localization of ITGA1	1	0.06	5.69	1.32
147	INT102853	Positive_regulation of Phosphorylation of Srgn	1	0.61	0.17	1.31
148	INT95116	Negative_regulation of PDGFA	24	0.57	19.56	1.29
149	INT14727	Regulation of FN1	13	0.45	5.95	1.26
150	INT120076	Positive_regulation of Gene_expression of Smad7	16	0.65	11.33	1.25
151	INT192349	Negative_regulation of Gene_expression of PDGFB	5	0.31	2.64	1.25
152	INT211198	Localization of SERPINH1	2	0.66	4.33	1.25
153	INT184313	Positive_regulation of Comp	4	0.55	4.23	1.24
154	INT97909	Binding of COMP	13	0.37	5.98	1.22
155	INT1787	Binding of Antxr1	13	0.32	2.62	1.22
156	INT166082	Positive_regulation of Gp6	9	0.61	1.69	1.22
157	INT145959	Negative_regulation of DSPP	19	0.57	2.75	1.21
158	INT105571	Gene_expression of SRGN	33	0.58	14.68	1.19
159	INT37849	Negative_regulation of Negative_regulation of Ache	3	0.43	0.8	1.19
160	INT103766	Positive_regulation of Phosphorylation of DDR1	2	0.13	1.94	1.19
161	INT333999	Protein_catabolism of Comp	1	0.72	1.77	1.19
162	INT201955	Regulation of DPP4	18	0.45	11.91	1.18
163	INT29772	Positive_regulation of Positive_regulation of Ache	3	0.50	0.09	1.18
164	INT50146	Gene_expression of Dcn	18	0.51	0.9	1.17
165	INT70886	Positive_regulation of Gene_expression of Pdgfb	13	0.45	12.57	1.17
166	INT187123	Negative_regulation of Positive_regulation of MMP9	7	0.42	2.54	1.17
167	INT6599	Binding of ITGA2	4	0.35	3.6	1.16
168	INT322041	Positive_regulation of Localization of Gp6	1	0.15	0.88	1.16
169	INT72599	Negative_regulation of Gene_expression of ITGA2	2	0.09	1.3	1.15
170	INT156613	Positive_regulation of Positive_regulation of FN1	2	0.45	3.33	1.15
171	INT322043	Localization of Gp6	1	0.22	0.88	1.15
172	INT91431	Positive_regulation of Gene_expression of CD44	18	0.69	9.25	1.12
173	INT210392	Regulation of PDGFA	10	0.36	11.41	1.12
174	INT27366	Negative_regulation of Negative_regulation of Ache	4	0.43	0.29	1.12
175	INT227925	Negative_regulation of Gene_expression of ITGB1	1	0.02	2.19	1.12
176	INT143956	Regulation of Positive_regulation of MMP9	5	0.40	2.61	1.11
177	INT184720	Negative_regulation of Smad3	8	0.55	5.23	1.1
178	INT110259	Negative_regulation of Vwf	6	0.42	3.3	1.1
179	INT265491	Gene_expression of CSPG4	16	0.58	7.27	1.07
180	INT191253	Negative_regulation of DDR1	13	0.25	10.05	1.05
181	INT96579	Negative_regulation of Negative_regulation of MMP9	5	0.40	4.55	1.04
182	INT208125	Gene_expression of DDR1	10	0.06	8.15	1.03
183	INT101614	Gene_expression of Dpp4	7	0.78	2.73	1.02
184	INT117774	Phosphorylation of Ddr1	1	0.15	0.37	1.02
185	INT63354	Negative_regulation of Gene_expression of CD44	4	0.50	4.76	1.01
186	INT235793	Positive_regulation of Gene_expression of DDR1	3	0.04	4.29	1.01
187	INT89853	Gene_expression of Srgn	12	0.44	1.13	1
188	INT115987	Positive_regulation of SPARC	4	0.44	1.52	0.99
189	INT89128	Binding of DSPP	7	0.32	2.24	0.98
190	INT126416	Gene_expression of Itga1	1	0.02	0.89	0.98
191	INT157573	Localization of Vwf	9	0.69	2.93	0.97
192	INT4099	Regulation of Antxr1	2	0.17	0.09	0.97
193	INT106386	Regulation of Gene_expression of CD44	8	0.27	3.66	0.96
194	INT226478	Protein_catabolism of DPP4	11	0.85	5.52	0.95
195	INT96774	Positive_regulation of Localization of Pdgfa	3	0.69	1.21	0.95
196	INT187135	Positive_regulation of Negative_regulation of MMP9	3	0.43	1.87	0.92
197	INT188317	Positive_regulation of Gene_expression of PDGFA	15	0.46	12.7	0.91
198	INT147880	Regulation of SRGN	28	0.33	13.99	0.9
199	INT118098	Protein_catabolism of COMP	5	0.66	2.76	0.9
200	INT116459	Negative_regulation of VWF	8	0.58	5.66	0.89