GO:0005639

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Name integral to nuclear inner membrane
Categary Component
Go Slim No
Go Link GO:0005639
Unique Molecular Interactions 59
Total Molecular Interactions 67
Total Single Events 663
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for integral to nuclear inner membrane. They are ordered first by their pain relevance and then by number of times they were reported for integral to nuclear inner membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT151779 Calca Positive_regulation of Transcription of P2rx7 1 0.02 0.54 0.87
2 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85
3 INT128861 LBR Positive_regulation of Positive_regulation of OPRM1 1 0.19 0.36 0.75
4 INT205706 P2rx7 Regulation of Gene_expression of Il18 1 0.21 1.35 0.7
5 INT246335 Fig4 Regulation of Localization of P2rx7 1 0.01 0 0.67
6 INT205702 P2rx7 Regulation of Gene_expression of Il1 1 0.04 1.38 0.67
7 INT96765 LBR Positive_regulation of Gene_expression of TP53INP2 1 0.11 0.5 0.62
8 INT205705 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of Il6 1 0.07 1.42 0.58
9 INT308174 Binding of TNF and P2rx7 1 0.02 0.84 0.56
10 INT176371 LBR Positive_regulation of IL12A 1 0.04 1.22 0.55
11 INT176367 LBR Positive_regulation of IFNA1 1 0.02 1.22 0.55
12 INT185490 Atp5o Negative_regulation of Gene_expression of P2rx7 1 0.01 0.87 0.53
13 INT216941 P2rx7 Regulation of Ryr1 1 0.01 0.55 0.52
14 INT278122 Negative_regulation of P2rx7 Negative_regulation of Binding of P2RX7 1 0.03 0 0.51
15 INT48102 Positive_regulation of LBR Positive_regulation of Positive_regulation of OR7A5 1 0.21 0 0.48
16 INT176366 LBR Regulation of IFNA1 1 0.04 0.91 0.46
17 INT169859 P2rx7 Regulation of Gene_expression of Grin1 1 0.17 0 0.43
18 INT176361 Positive_regulation of LBR Positive_regulation of Gene_expression of IL18 1 0.10 0.84 0.39
19 INT205704 P2rx7 Regulation of Localization of Il18 1 0.09 0.67 0.35
20 INT176363 IFNA1 Regulation of Positive_regulation of LBR 1 0.04 0.69 0.34
21 INT205713 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of IL8 1 0.03 0.77 0.33
22 INT217025 P2rx7 Regulation of Gene_expression of Ik 1 0.00 0.25 0.33
23 INT217024 Regulation of P2rx7 Regulation of Gene_expression of Ik 1 0.00 0.25 0.33
24 INT205703 P2rx7 Regulation of Positive_regulation of Casp1 1 0.11 0.66 0.33
25 INT205711 P2rx7 Regulation of Localization of IL8 1 0.02 0.92 0.33
26 INT307017 LBR Positive_regulation of Gene_expression of TNF 1 0.02 0.58 0.32
27 INT307014 LBR Positive_regulation of Gene_expression of IL6 1 0.01 0.58 0.32
28 INT145682 Binding of P2rx4 and P2rx7 2 0.25 0.36 0.31
29 INT21321 Pomc Positive_regulation of LBR 1 0.04 0 0.31
30 INT215789 Fig4 Positive_regulation of Localization of P2rx7 1 0.03 0.53 0.29
31 INT205701 P2rx7 Positive_regulation of Il1 1 0.04 0.8 0.25
32 INT185489 Atp5o Negative_regulation of P2rx7 1 0.01 0.29 0.24
33 INT216911 Positive_regulation of P2rx7 Positive_regulation of Localization of Plg 1 0.02 0.13 0.23
34 INT107219 Binding of P2rx7 and Atp5o 1 0.03 0.07 0.21
35 INT216946 P2rx7 Regulation of Il10 1 0.28 0.17 0.21
36 INT107223 APEH Negative_regulation of P2rx7 1 0.00 0.13 0.21
37 INT205710 CAMP Positive_regulation of P2rx7 1 0.02 0.47 0.19
38 INT182326 LBR Positive_regulation of Gene_expression of Birc5 1 0.00 0.46 0.17
39 INT270827 P2rx7 Positive_regulation of Localization of Panx1 1 0.41 0.18 0.13
40 INT216945 Positive_regulation of P2rx7 Positive_regulation of Positive_regulation of Casp1 1 0.14 0.18 0.12
41 INT74504 Binding of P2rx7 and Rp2 1 0.02 0.19 0.11
42 INT39207 LBR Positive_regulation of Gene_expression of IL2 1 0.23 0 0.11
43 INT205708 Binding of Icam1 and P2rx7 1 0.08 1.03 0.09
44 INT217036 IRF6 Positive_regulation of Gene_expression of P2rx7 1 0.02 0 0.09
45 INT270824 Binding of P2rx7 and Panx1 1 0.34 0.15 0.09
46 INT304464 Binding of P2rx7 and P2rx6 1 0.05 0 0.09
47 INT243156 Positive_regulation of P2rx7 Positive_regulation of NOS1 1 0.00 0.08 0.08
48 INT270829 P2rx7 Positive_regulation of Panx1 1 0.66 0.08 0.08
49 INT340420 Hmmr Regulation of P2rx7 1 0.01 1.12 0.08
50 INT270835 Positive_regulation of P2rx7 Positive_regulation of Localization of DPEP1 1 0.04 0.08 0.07
51 INT340427 Positive_regulation of P2rx7 Positive_regulation of Regulation of Pkhd1 1 0.01 1 0.05
52 INT307007 MT1JP Positive_regulation of Localization of LBR 1 0.01 0 0.05
53 INT270825 P2rx7 Positive_regulation of Slc37a4 1 0.01 0 0.04
54 INT323707 LBR Positive_regulation of MIR146A 1 0.02 0.1 0.03
55 INT217031 Binding of P2rx7 and Positive_regulation of Casp1 1 0.02 0 0
56 INT324053 Binding of Banf1 and Lemd3 1 0.20 0.15 0
57 INT217032 Binding of P2rx7 and Positive_regulation of Il1 1 0.02 0 0
58 INT216942 Positive_regulation of P2rx7 Positive_regulation of Casp1 1 0.14 0 0
59 INT307460 P2rx7 Positive_regulation of Phosphorylation of Gsk3a 1 0.02 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for integral to nuclear inner membrane. They are ordered first by their pain relevance and then by number of times they were reported in integral to nuclear inner membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
2 INT88327 Gene_expression of P2rx7 109 0.77 48.86 22.41
3 INT23787 Positive_regulation of P2rx7 36 0.68 23.54 19.45
4 INT121241 Positive_regulation of P2rx7 65 0.69 40.94 13.59
5 INT73427 Localization of P2rx7 24 0.79 8.65 9.87
6 INT48257 Negative_regulation of P2rx7 18 0.41 7.82 8.42
7 INT88326 Negative_regulation of P2rx7 16 0.58 8.77 6.25
8 INT94608 Regulation of P2rx7 19 0.23 8.06 6.19
9 INT68882 Binding of P2rx7 16 0.23 4.33 6.17
10 INT145680 Regulation of P2rx7 22 0.61 11.92 5.42
11 INT185484 Positive_regulation of Gene_expression of P2rx7 8 0.31 7.44 4.28
12 INT144830 Positive_regulation of Gene_expression of P2rx7 22 0.68 9.78 3.92
13 INT129441 Regulation of Gene_expression of P2rx7 8 0.24 4.29 3.32
14 INT144828 Binding of P2rx7 19 0.47 7.84 3.16
15 INT48106 Positive_regulation of LBR 11 0.49 5.14 2.86
16 INT11139 Gene_expression of LBR 20 0.75 5.13 2.78
17 INT107216 Negative_regulation of Gene_expression of P2rx7 10 0.56 3.39 2.61
18 INT144829 Localization of P2rx7 12 0.79 2.92 2.12
19 INT44773 Negative_regulation of LBR 6 0.57 2.32 2.03
20 INT216936 Negative_regulation of Gene_expression of P2rx7 5 0.42 2.59 1.84
21 INT23786 Positive_regulation of Positive_regulation of P2rx7 5 0.44 2.21 1.58
22 INT125735 Transcription of P2rx7 3 0.62 1.34 1.58
23 INT215757 Transcription of P2rx7 3 0.21 1.84 1.45
24 INT205691 Regulation of Gene_expression of P2rx7 5 0.44 3.25 1.42
25 INT205690 Positive_regulation of Positive_regulation of P2rx7 14 0.68 6.26 1.3
26 INT28643 Positive_regulation of Gene_expression of LBR 3 0.11 2.43 1.16
27 INT31805 Localization of LBR 3 0.73 1.23 1.13
28 INT71378 Transcription of LBR 2 0.07 1.34 1.03
29 INT216661 Regulation of Positive_regulation of P2rx7 1 0.07 0 1
30 INT113887 Positive_regulation of Negative_regulation of P2rx7 1 0.22 1.02 0.96
31 INT44772 Negative_regulation of Negative_regulation of LBR 2 0.42 0.38 0.92
32 INT151776 Positive_regulation of Transcription of P2rx7 1 0.03 0.53 0.86
33 INT271589 Regulation of Transcription of P2rx7 1 0.05 0.5 0.78
34 INT125734 Negative_regulation of Transcription of P2rx7 1 0.38 0.81 0.67
35 INT46148 Binding of LBR 5 0.31 1.58 0.64
36 INT185485 Negative_regulation of Localization of P2rx7 1 0.26 0.95 0.62
37 INT307027 Positive_regulation of Localization of LBR 1 0.05 0.82 0.61
38 INT176375 Positive_regulation of Positive_regulation of LBR 1 0.10 1.12 0.53
39 INT153099 Negative_regulation of Positive_regulation of P2rx7 1 0.42 0.25 0.5
40 INT215732 Negative_regulation of Binding of P2rx7 1 0.11 0.74 0.49
41 INT278114 Negative_regulation of Negative_regulation of P2rx7 1 0.21 0 0.45
42 INT215741 Positive_regulation of Transcription of P2rx7 1 0.15 1.15 0.43
43 INT3044 Regulation of LBR 2 0.44 0.1 0.35
44 INT121239 Regulation of Positive_regulation of P2rx7 2 0.61 1.32 0.32
45 INT216937 Regulation of Binding of P2rx7 1 0.44 0.08 0.29
46 INT216938 Negative_regulation of Localization of P2rx7 1 0.37 0.25 0.24
47 INT216940 Negative_regulation of Binding of P2rx7 1 0.37 0.15 0.2
48 INT216889 Phosphorylation of P2rx7 1 0.23 0 0.18
49 INT307467 Regulation of Binding of P2rx7 1 0.08 0 0.16
50 INT270813 Positive_regulation of Localization of P2rx7 1 0.46 0.24 0.15
51 INT64474 Regulation of Positive_regulation of LBR 1 0.22 0.08 0.13
52 INT324046 Gene_expression of Lemd3 1 0.67 1.69 0.1
53 INT307481 Phosphorylation of P2rx7 1 0.15 0.35 0.08
54 INT55486 Negative_regulation of Positive_regulation of LBR 1 0.41 1.07 0.08
55 INT307480 Positive_regulation of Phosphorylation of P2rx7 1 0.09 0.35 0.08
56 INT303974 Phosphorylation of LBR 2 0.79 0.24 0.06
57 INT303973 Negative_regulation of Phosphorylation of LBR 1 0.41 0.14 0.06
58 INT324047 Binding of Lemd3 1 0.48 3.18 0
59 INT330661 Regulation of Phosphorylation of LBR 1 0.03 0.1 0
60 INT324043 Localization of Lemd3 1 0.75 0 0
61 INT324044 Negative_regulation of Lemd3 1 0.43 2.86 0
62 INT298394 Positive_regulation of Binding of LBR 1 0.05 0.31 0
63 INT324048 Positive_regulation of Negative_regulation of Lemd3 1 0.50 0.2 0
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