GO:0005958

Name DNA-dependent protein kinase-DNA ligase 4 complex Categary Component Go Slim No Go Link GO:0005958

Unique Molecular Interactions 41 Total Molecular Interactions 70 Total Single Events 150 Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for DNA-dependent protein kinase-DNA ligase 4 complex. They are ordered first by their pain relevance and then by number of times they were reported for DNA-dependent protein kinase-DNA ligase 4 complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT322266	Binding of LIG4 and NOS3	1	0.02	2.35	0.82
2	INT117412	RYBP Negative_regulation of LIG4	1	0.00	0.42	0.76
3	INT322048	Prkdc Negative_regulation of Col7a1	1	0.00	0.45	0.5
4	INT125514	Positive_regulation of PRKDC Positive_regulation of Positive_regulation of NFKB1	1	0.07	0.44	0.26
5	INT309513	Binding of Xrcc6 and Htt	1	0.30	3.69	0.21
6	INT350736	PRKDC Negative_regulation of CA2	1	0.02	0.16	0.11
7	INT350735	PRKDC Negative_regulation of ITPR3	1	0.01	0.16	0.11
8	INT309511	Binding of Xrcc6 and Xrcc5	1	0.18	1.18	0.08
9	INT249201	PRKDC Regulation of Regulation of CYBB	1	0.01	0.09	0.05
10	INT352669	PRKDC Positive_regulation of Memor1	1	0.00	1.02	0.04
11	INT306511	Binding of XRCC6 and Ung	1	0.00	0.78	0
12	INT249169	PMAIP1 Positive_regulation of PRKDC	1	0.00	0	0
13	INT284919	XRCC6 Negative_regulation of BAX	1	0.01	0.64	0
14	INT309515	Xrcc6 Regulation of Gene_expression of Htt	1	0.32	0.08	0
15	INT225593	Ncoa6 Positive_regulation of Prkdc	1	0.02	0	0
16	INT306509	Binding of XRCC6 and Clu	1	0.37	0.27	0
17	INT225480	Binding of Prkdc and Acsl1	1	0.00	0	0
18	INT276904	Regulation of Binding of Egfr and Prkdc	1	0.03	0.42	0
19	INT225613	TARBP2 Positive_regulation of Prkdc	1	0.00	0	0
20	INT225642	Binding of XRCC5 and Acsl1	1	0.01	0	0
21	INT309521	PRKDC Regulation of Gene_expression of Htt	1	0.41	0.08	0
22	INT309517	Binding of Bax and Xrcc6	1	0.15	0.5	0
23	INT309519	Xrcc5 Regulation of Gene_expression of Htt	1	0.18	0.08	0
24	INT253014	Binding of XRCC5 and Zic2	1	0.00	0.14	0
25	INT309512	Negative_regulation of Xrcc6 Positive_regulation of Phosphorylation of Gopc	1	0.20	0.17	0
26	INT276905	Binding of Egfr and Prkdc	1	0.04	0.41	0
27	INT225614	Binding of XRCC5 and Parp1	1	0.09	0	0
28	INT252904	Binding of PRKDC and XRCC5	1	0.00	0.14	0
29	INT253013	Binding of PRKDC and Zic2	1	0.00	0.14	0
30	INT309518	Negative_regulation of Binding of Bax and Xrcc6	1	0.16	0.25	0
31	INT323185	Binding of LIG4 and OGG1	1	0.02	0.32	0
32	INT309516	Htt Positive_regulation of Gene_expression of Xrcc6	1	0.49	0.06	0
33	INT309509	Negative_regulation of Binding of Xrcc6 and Htt	1	0.31	0.41	0
34	INT309510	Htt Regulation of Gene_expression of Xrcc6	1	0.19	0.15	0
35	INT309508	Htt Negative_regulation of Binding of Xrcc6	1	0.31	0.48	0
36	INT309514	Positive_regulation of Binding of Xrcc6 and Htt	1	0.33	0	0

Single Events

The table below shows the top 100 pain related interactions that have been reported for DNA-dependent protein kinase-DNA ligase 4 complex. They are ordered first by their pain relevance and then by number of times they were reported in DNA-dependent protein kinase-DNA ligase 4 complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT108148	Positive_regulation of Prkdc	2	0.16	0.49	2.31
2	INT117415	Negative_regulation of LIG4	4	0.04	1.59	2.17
3	INT118155	Regulation of Positive_regulation of Prkdc	1	0.10	0.49	1.42
4	INT125525	Positive_regulation of PRKDC	7	0.45	2.72	1.21
5	INT166935	Gene_expression of Prkdc	10	0.65	3.14	0.9
6	INT125526	Gene_expression of PRKDC	5	0.58	4	0.74
7	INT333877	Protein_catabolism of LIG4	2	0.03	2.03	0.57
8	INT309465	Gene_expression of Xrcc6	24	0.59	5.49	0.43
9	INT125524	Positive_regulation of Gene_expression of PRKDC	2	0.09	1	0.29
10	INT180393	Positive_regulation of Gene_expression of Prkdc	3	0.49	1.17	0.26
11	INT327888	Localization of Prkdc	1	0.14	1.11	0.23
12	INT309493	Binding of Xrcc6	1	0.37	3	0.2
13	INT142384	Gene_expression of XRCC6	3	0.58	1.98	0.16
14	INT309492	Positive_regulation of Gene_expression of Xrcc6	1	0.38	1.29	0.13
15	INT290726	Binding of Prkdc	1	0.03	1.05	0.13
16	INT352666	Regulation of PRKDC	1	0.01	0.36	0.09
17	INT249260	Positive_regulation of Phosphorylation of PRKDC	1	0.03	0.06	0.08
18	INT309460	Binding of Xrcc5	1	0.16	0.09	0.08
19	INT249280	Phosphorylation of PRKDC	2	0.13	0.3	0.07
20	INT309478	Regulation of Gene_expression of Xrcc6	1	0.21	0.36	0.07
21	INT352653	Positive_regulation of Positive_regulation of PRKDC	1	0.01	0.56	0.03
22	INT180394	Phosphorylation of Prkdc	2	0.07	0.6	0
23	INT284963	Binding of XRCC6	2	0.36	1.57	0
24	INT309463	Regulation of Negative_regulation of Xrcc6	1	0.18	0.15	0
25	INT309499	Localization of Xrcc6	1	0.57	0.13	0
26	INT352658	Negative_regulation of PRKDC	1	0.01	0.33	0
27	INT309491	Negative_regulation of Gene_expression of Xrcc6	1	0.32	0.56	0
28	INT350511	Negative_regulation of XRCC6	1	0.08	0.58	0
29	INT309475	Positive_regulation of Binding of Xrcc6	1	0.53	0	0
30	INT309464	Negative_regulation of Negative_regulation of Xrcc6	1	0.45	0.09	0
31	INT309472	Protein_catabolism of Xrcc6	1	0.67	0.43	0
32	INT309468	Transcription of Xrcc6	1	0.52	0.24	0
33	INT350522	Positive_regulation of Gene_expression of XRCC6	1	0.11	0.53	0
34	INT348467	Positive_regulation of XRCC5	1	0.25	0.43	0
35	INT309467	Gene_expression of Xrcc5	1	0.26	0.1	0
36	INT309483	Positive_regulation of Xrcc5	1	0.20	0.1	0
37	INT309461	Negative_regulation of Xrcc6	1	0.45	0.92	0
38	INT309476	Positive_regulation of Protein_catabolism of Xrcc6	1	0.38	0.43	0
39	INT309502	Positive_regulation of Xrcc6	1	0.38	1.58	0
40	INT309479	Negative_regulation of Binding of Xrcc6	1	0.28	0.25	0
41	INT309488	Negative_regulation of Localization of Xrcc6	1	0.32	0.13	0
42	INT309503	Phosphorylation of Xrcc6	1	0.54	0.55	0
43	INT323201	Binding of LIG4	1	0.03	0.32	0
44	INT225463	Binding of XRCC5	1	0.36	0	0
45	INT309480	Positive_regulation of Negative_regulation of Xrcc6	1	0.38	0.12	0