GO:0005958

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Latest revision as of 22:53, 21 January 2013

Name DNA-dependent protein kinase-DNA ligase 4 complex
Categary Component
Go Slim No
Go Link GO:0005958
Unique Molecular Interactions 41
Total Molecular Interactions 70
Total Single Events 150
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

[edit] Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for DNA-dependent protein kinase-DNA ligase 4 complex. They are ordered first by their pain relevance and then by number of times they were reported for DNA-dependent protein kinase-DNA ligase 4 complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT322266 Binding of LIG4 and NOS3 1 0.02 2.35 0.82
2 INT117412 RYBP Negative_regulation of LIG4 1 0.00 0.42 0.76
3 INT322048 Prkdc Negative_regulation of Col7a1 1 0.00 0.45 0.5
4 INT125514 Positive_regulation of PRKDC Positive_regulation of Positive_regulation of NFKB1 1 0.07 0.44 0.26
5 INT309513 Binding of Xrcc6 and Htt 1 0.30 3.69 0.21
6 INT350736 PRKDC Negative_regulation of CA2 1 0.02 0.16 0.11
7 INT350735 PRKDC Negative_regulation of ITPR3 1 0.01 0.16 0.11
8 INT309511 Binding of Xrcc6 and Xrcc5 1 0.18 1.18 0.08
9 INT249201 PRKDC Regulation of Regulation of CYBB 1 0.01 0.09 0.05
10 INT352669 PRKDC Positive_regulation of Memor1 1 0.00 1.02 0.04
11 INT306511 Binding of XRCC6 and Ung 1 0.00 0.78 0
12 INT249169 PMAIP1 Positive_regulation of PRKDC 1 0.00 0 0
13 INT284919 XRCC6 Negative_regulation of BAX 1 0.01 0.64 0
14 INT309515 Xrcc6 Regulation of Gene_expression of Htt 1 0.32 0.08 0
15 INT225593 Ncoa6 Positive_regulation of Prkdc 1 0.02 0 0
16 INT306509 Binding of XRCC6 and Clu 1 0.37 0.27 0
17 INT225480 Binding of Prkdc and Acsl1 1 0.00 0 0
18 INT276904 Regulation of Binding of Egfr and Prkdc 1 0.03 0.42 0
19 INT225613 TARBP2 Positive_regulation of Prkdc 1 0.00 0 0
20 INT225642 Binding of XRCC5 and Acsl1 1 0.01 0 0
21 INT309521 PRKDC Regulation of Gene_expression of Htt 1 0.41 0.08 0
22 INT309517 Binding of Bax and Xrcc6 1 0.15 0.5 0
23 INT309519 Xrcc5 Regulation of Gene_expression of Htt 1 0.18 0.08 0
24 INT253014 Binding of XRCC5 and Zic2 1 0.00 0.14 0
25 INT309512 Negative_regulation of Xrcc6 Positive_regulation of Phosphorylation of Gopc 1 0.20 0.17 0
26 INT276905 Binding of Egfr and Prkdc 1 0.04 0.41 0
27 INT225614 Binding of XRCC5 and Parp1 1 0.09 0 0
28 INT252904 Binding of PRKDC and XRCC5 1 0.00 0.14 0
29 INT253013 Binding of PRKDC and Zic2 1 0.00 0.14 0
30 INT309518 Negative_regulation of Binding of Bax and Xrcc6 1 0.16 0.25 0
31 INT323185 Binding of LIG4 and OGG1 1 0.02 0.32 0
32 INT309516 Htt Positive_regulation of Gene_expression of Xrcc6 1 0.49 0.06 0
33 INT309509 Negative_regulation of Binding of Xrcc6 and Htt 1 0.31 0.41 0
34 INT309510 Htt Regulation of Gene_expression of Xrcc6 1 0.19 0.15 0
35 INT309508 Htt Negative_regulation of Binding of Xrcc6 1 0.31 0.48 0
36 INT309514 Positive_regulation of Binding of Xrcc6 and Htt 1 0.33 0 0

[edit] Single Events

The table below shows the top 100 pain related interactions that have been reported for DNA-dependent protein kinase-DNA ligase 4 complex. They are ordered first by their pain relevance and then by number of times they were reported in DNA-dependent protein kinase-DNA ligase 4 complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT108148 Positive_regulation of Prkdc 2 0.16 0.49 2.31
2 INT117415 Negative_regulation of LIG4 4 0.04 1.59 2.17
3 INT118155 Regulation of Positive_regulation of Prkdc 1 0.10 0.49 1.42
4 INT125525 Positive_regulation of PRKDC 7 0.45 2.72 1.21
5 INT166935 Gene_expression of Prkdc 10 0.65 3.14 0.9
6 INT125526 Gene_expression of PRKDC 5 0.58 4 0.74
7 INT333877 Protein_catabolism of LIG4 2 0.03 2.03 0.57
8 INT309465 Gene_expression of Xrcc6 24 0.59 5.49 0.43
9 INT125524 Positive_regulation of Gene_expression of PRKDC 2 0.09 1 0.29
10 INT180393 Positive_regulation of Gene_expression of Prkdc 3 0.49 1.17 0.26
11 INT327888 Localization of Prkdc 1 0.14 1.11 0.23
12 INT309493 Binding of Xrcc6 1 0.37 3 0.2
13 INT142384 Gene_expression of XRCC6 3 0.58 1.98 0.16
14 INT309492 Positive_regulation of Gene_expression of Xrcc6 1 0.38 1.29 0.13
15 INT290726 Binding of Prkdc 1 0.03 1.05 0.13
16 INT352666 Regulation of PRKDC 1 0.01 0.36 0.09
17 INT249260 Positive_regulation of Phosphorylation of PRKDC 1 0.03 0.06 0.08
18 INT309460 Binding of Xrcc5 1 0.16 0.09 0.08
19 INT249280 Phosphorylation of PRKDC 2 0.13 0.3 0.07
20 INT309478 Regulation of Gene_expression of Xrcc6 1 0.21 0.36 0.07
21 INT352653 Positive_regulation of Positive_regulation of PRKDC 1 0.01 0.56 0.03
22 INT180394 Phosphorylation of Prkdc 2 0.07 0.6 0
23 INT284963 Binding of XRCC6 2 0.36 1.57 0
24 INT309463 Regulation of Negative_regulation of Xrcc6 1 0.18 0.15 0
25 INT309499 Localization of Xrcc6 1 0.57 0.13 0
26 INT352658 Negative_regulation of PRKDC 1 0.01 0.33 0
27 INT309491 Negative_regulation of Gene_expression of Xrcc6 1 0.32 0.56 0
28 INT350511 Negative_regulation of XRCC6 1 0.08 0.58 0
29 INT309475 Positive_regulation of Binding of Xrcc6 1 0.53 0 0
30 INT309464 Negative_regulation of Negative_regulation of Xrcc6 1 0.45 0.09 0
31 INT309472 Protein_catabolism of Xrcc6 1 0.67 0.43 0
32 INT309468 Transcription of Xrcc6 1 0.52 0.24 0
33 INT350522 Positive_regulation of Gene_expression of XRCC6 1 0.11 0.53 0
34 INT348467 Positive_regulation of XRCC5 1 0.25 0.43 0
35 INT309467 Gene_expression of Xrcc5 1 0.26 0.1 0
36 INT309483 Positive_regulation of Xrcc5 1 0.20 0.1 0
37 INT309461 Negative_regulation of Xrcc6 1 0.45 0.92 0
38 INT309476 Positive_regulation of Protein_catabolism of Xrcc6 1 0.38 0.43 0
39 INT309502 Positive_regulation of Xrcc6 1 0.38 1.58 0
40 INT309479 Negative_regulation of Binding of Xrcc6 1 0.28 0.25 0
41 INT309488 Negative_regulation of Localization of Xrcc6 1 0.32 0.13 0
42 INT309503 Phosphorylation of Xrcc6 1 0.54 0.55 0
43 INT323201 Binding of LIG4 1 0.03 0.32 0
44 INT225463 Binding of XRCC5 1 0.36 0 0
45 INT309480 Positive_regulation of Negative_regulation of Xrcc6 1 0.38 0.12 0
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