GO:0006621

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Name protein retention in ER lumen
Categary Process
Go Slim No
Go Link GO:0006621
Unique Molecular Interactions 8
Total Molecular Interactions 10
Total Single Events 77
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein retention in ER lumen. They are ordered first by their pain relevance and then by number of times they were reported for protein retention in ER lumen. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT227498 Binding of KDELR1 and TMED4 1 0.00 0.37 0.67
2 INT197232 Binding of Grik5 and Kars 1 0.17 0.1 0.25
3 INT336993 Binding of PDIA3 and CALCRL 1 0.00 0 0.06
4 INT272600 Binding of Dlg4 and Grik5 1 0.20 0 0.03
5 INT245071 Binding of CXCL12 and KDELR1 1 0.04 1.49 0
6 INT333926 Binding of PDIA3 and ERLEC1 1 0.02 0.18 0
7 INT240215 Binding of SEC31A and PDIA2 1 0.00 0 0
8 INT333931 Binding of CALR and PDIA3 1 0.18 0.18 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein retention in ER lumen. They are ordered first by their pain relevance and then by number of times they were reported in protein retention in ER lumen. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT227504 Gene_expression of KDELR1 8 0.09 5.47 2.43
2 INT212103 Negative_regulation of KDELR1 4 0.13 1.82 2.05
3 INT169472 Gene_expression of PDIA2 15 0.58 7.88 0.96
4 INT168534 Gene_expression of Grik5 3 0.38 0.64 0.9
5 INT78238 Binding of PDIA3 2 0.36 0.87 0.54
6 INT79311 Positive_regulation of Positive_regulation of PDIA3 1 0.49 0.34 0.47
7 INT169473 Positive_regulation of Localization of PDIA2 2 0.18 0.89 0.43
8 INT169476 Localization of PDIA2 3 0.27 1.09 0.42
9 INT168536 Localization of Grik5 1 0.07 0.09 0.34
10 INT168539 Regulation of Gene_expression of Grik5 1 0.02 0.09 0.34
11 INT227505 Binding of KDELR1 2 0.06 1.85 0.33
12 INT227502 Positive_regulation of Gene_expression of KDELR1 1 0.07 0.33 0.32
13 INT228158 Positive_regulation of PDIA2 7 0.44 2.33 0.28
14 INT79313 Positive_regulation of PDIA3 2 0.49 0.27 0.23
15 INT131584 Gene_expression of PDIA3 2 0.33 0.7 0.15
16 INT228155 Binding of PDIA2 4 0.32 0.62 0.14
17 INT223879 Negative_regulation of PDIA2 3 0.37 0.46 0.09
18 INT223878 Positive_regulation of Gene_expression of PDIA2 2 0.42 0 0
19 INT119488 Regulation of KDELR1 1 0.19 0.07 0
20 INT337006 Positive_regulation of Binding of PDIA3 1 0.21 0 0
21 INT259389 Regulation of PDIA2 1 0.24 0 0
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