GO:0007281

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Name germ cell development
Categary Process
Go Slim No
Go Link GO:0007281
Unique Molecular Interactions 917
Total Molecular Interactions 1282
Total Single Events 9092
Pain Genes Associated 41

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for germ cell development. They are ordered first by their pain relevance and then by number of times they were reported for germ cell development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 1 0.10 3.92 7.2
2 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
3 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
4 INT166134 Binding of Cxcl12 and Cxcr4 3 0.49 5.69 3.17
5 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
6 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
7 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
8 INT107578 Kitl Negative_regulation of Grin2b 1 0.12 2.05 2.36
9 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
10 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2
11 INT140019 Avp Positive_regulation of Localization of Kitl 1 0.00 1 2.13
12 INT132229 Binding of Akt1 and Sh2d6 1 0.09 0.98 1.8
13 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
14 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
15 INT140023 Avp Positive_regulation of Gene_expression of Kitl 1 0.00 0.76 1.62
16 INT54601 Binding of Mtor and Ache 1 0.20 0.8 1.58
17 INT214372 Ptprq Positive_regulation of Akt1 1 0.04 0.88 1.43
18 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41
19 INT121802 DEAF1 Negative_regulation of HTR1A 1 0.46 0.88 1.29
20 INT149844 Negative_regulation of Cxcl12 Negative_regulation of C19orf10 1 0.16 0.45 1.26
21 INT149845 Cxcl12 Negative_regulation of C19orf10 1 0.16 0.45 1.24
22 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22
23 INT107579 Kitl Negative_regulation of Grin2a 1 0.10 1.02 1.18
24 INT99577 Binding of KITLG and Kit 3 0.34 2.33 1.11
25 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
26 INT317516 Binding of Oprm1 and Negative_regulation of Positive_regulation of Akt1 1 0.17 0.1 1.11
27 INT323175 PRKCA Positive_regulation of Akt1 1 0.02 0 1.1
28 INT105109 Cxcl12 Positive_regulation of JUN 1 0.01 1.07 1.05
29 INT151218 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Akt1 1 0.00 0.26 1.03
30 INT53844 Penk Regulation of Kitl 1 0.00 0.9 1
31 INT317554 Akt1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1
32 INT53845 Positive_regulation of Penk Regulation of Kitl 1 0.00 0.9 1
33 INT275409 Binding of ITIH4 and Cxcr4 1 0.09 2.87 0.97
34 INT275386 Binding of Cxcr4 and Htatsf1 1 0.01 3.25 0.97
35 INT317567 Binding of Akt1 and Nos1 1 0.22 0 0.96
36 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
37 INT114883 Akt1 Regulation of Pik3r1 2 0.16 0.65 0.92
38 INT166135 Regulation of Binding of Cxcl12 and Cxcr4 1 0.30 0.9 0.91
39 INT317541 Oprd1 Negative_regulation of Akt1 1 0.06 0 0.91
40 INT249012 Binding of Akt1 and Gabrg1 1 0.01 0 0.9
41 INT132226 Binding of Akt1 and Pik3cg 1 0.30 0.49 0.9
42 INT253992 Cxcl12 Positive_regulation of Mif 1 0.46 1.31 0.88
43 INT199109 Binding of Akt1 and Arhgdia 1 0.02 2.73 0.87
44 INT254004 Cxcl12 Positive_regulation of Cxcr4 1 0.47 1.29 0.86
45 INT253995 Binding of Cxcl12 and Cyp3a23/3a1 1 0.06 1.28 0.85
46 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
47 INT97056 Cpz Regulation of Gene_expression of Bcl2l1 1 0.22 0.57 0.83
48 INT149558 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.00 0 0.82
49 INT317556 Phosphorylation of Gopc Positive_regulation of Akt1 1 0.10 0.08 0.82
50 INT317514 Akt1 Regulation of Localization of Oprm1 1 0.21 0.07 0.82
51 INT99578 Binding of CEL and Kit 1 0.04 1.07 0.81
52 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8
53 INT151453 Gtf3a Regulation of Kit 1 0.04 0.25 0.78
54 INT111888 Akt1 Regulation of Regulation of Oprm1 1 0.04 0 0.77
55 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
56 INT335592 Ltp Positive_regulation of Positive_regulation of Akt1 1 0.01 0.19 0.74
57 INT106527 Akt1 Positive_regulation of Jun 1 0.05 0.53 0.74
58 INT276213 Pten Regulation of Phosphorylation of Akt1 1 0.51 0.61 0.72
59 INT298728 Akt1 Positive_regulation of Rela 1 0.01 1.03 0.67
60 INT289357 Ngfr Positive_regulation of Akt1 1 0.03 3.1 0.66
61 INT308668 Akt1 Positive_regulation of Nos3 3 0.05 4.61 0.65
62 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
63 INT296790 Tlr9 Regulation of Bax 1 0.14 0.76 0.65
64 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
65 INT83800 Aap Regulation of Gene_expression of Bcl2l1 1 0.28 0.58 0.64
66 INT134047 Fitm1 Positive_regulation of Phosphorylation of Akt1 1 0.05 0.21 0.63
67 INT134044 Positive_regulation of Fitm1 Positive_regulation of Phosphorylation of Akt1 1 0.05 0.21 0.63
68 INT200808 Binding of Akt1 and Insrr 2 0.00 0.98 0.61
69 INT282286 Akt1 Positive_regulation of Pak1 1 0.15 0.24 0.61
70 INT21607 ACE Positive_regulation of ANGPT2 1 0.03 0.13 0.61
71 INT112699 Bid Regulation of Bax 1 0.25 0.51 0.61
72 INT139901 Ins1 Positive_regulation of Akt1 9 0.31 4.58 0.6
73 INT1211 Binding of Kitl and Cpz 1 0.27 0 0.58
74 INT248994 Binding of Akt1 and Ptar1 1 0.00 0 0.58
75 INT1210 Negative_regulation of Binding of Kitl and Cpz 1 0.33 0 0.58
76 INT323176 PRKCA Positive_regulation of Phosphorylation of Akt1 1 0.02 0 0.56
77 INT302832 Tnfsf10 Positive_regulation of Akt1 1 0.04 1.63 0.56
78 INT253998 Cyp3a23/3a1 Positive_regulation of Binding of Cxcl12 1 0.10 0.65 0.55
79 INT253990 Cyp3a23/3a1 Positive_regulation of Cxcl12 1 0.09 0.65 0.55
80 INT114064 Agtr2 Positive_regulation of Phosphorylation of Akt1 1 0.24 0.41 0.54
81 INT282284 Cpox Positive_regulation of Akt1 1 0.02 0.47 0.54
82 INT282282 Ptger2 Positive_regulation of Akt1 1 0.03 0.47 0.54
83 INT162994 Binding of Akt1 and Trib3 1 0.04 0.09 0.54
84 INT127320 Gpx3 Regulation of Akt1 2 0.00 3.11 0.53
85 INT105110 Cxcl12 Positive_regulation of NFKB1 1 0.06 0.54 0.53
86 INT317523 Oprm1 Positive_regulation of Gene_expression of Akt1 1 0.32 0.05 0.53
87 INT105108 Negative_regulation of Cxcl12 Positive_regulation of NFKB1 1 0.05 0.54 0.53
88 INT109307 Pik3r1 Positive_regulation of Phosphorylation of Akt1 1 0.29 0.4 0.53
89 INT317574 Oprm1 Positive_regulation of Akt1 1 0.22 0.05 0.52
90 INT275388 Binding of Lamp1 and Cxcr4 1 0.01 1.45 0.52
91 INT275403 Binding of Cxcr4 and GOLPH3 1 0.00 1.45 0.52
92 INT194916 Kitl Positive_regulation of Gene_expression of Mmp1a 1 0.00 0.85 0.52
93 INT194919 Kitl Positive_regulation of Gene_expression of VEGFA 1 0.01 0.85 0.52
94 INT151221 Negative_regulation of SIGMAR1 Negative_regulation of Akt1 1 0.00 0.13 0.51
95 INT102844 Pdc Regulation of Akt1 1 0.03 0 0.49
96 INT134042 Jak2 Regulation of Akt1 1 0.18 0.13 0.47
97 INT309126 Edc4 Positive_regulation of Akt1 1 0.02 0.99 0.47
98 INT309144 Dlat Positive_regulation of Akt1 1 0.03 0.99 0.47
99 INT276207 Binding of Akt1 and Myo1f 1 0.11 0.05 0.47
100 INT114065 Akt1 Regulation of Gene_expression of Insr 1 0.13 0.28 0.46
101 INT276218 Binding of Akt1 and Pten 1 0.26 0.08 0.46
102 INT275399 Binding of ERVW-1 and Cxcr4 1 0.00 1.73 0.46
103 INT238638 Gopc Negative_regulation of Gene_expression of Bax 1 0.04 0.85 0.45
104 INT281126 Binding of Ccr2 and Cxcr4 1 0.30 0.32 0.44
105 INT253996 Binding of Cxcr2 and Cxcr4 1 0.18 0.81 0.44
106 INT139900 Kcne2 Positive_regulation of Akt1 1 0.06 2.95 0.44
107 INT348785 Ins1 Positive_regulation of Phosphorylation of Akt1 1 0.17 3.5 0.42
108 INT322396 Hist1h1t Positive_regulation of Akt1 1 0.01 0 0.42
109 INT40208 Binding of Eef1a1 and Hils1 1 0.01 0.22 0.42
110 INT322395 Akt1 Regulation of Pik3cb 1 0.08 0 0.42
111 INT273111 Bdnf Positive_regulation of Positive_regulation of Mtor 1 0.44 0.07 0.42
112 INT122749 Cyp3a23/3a1 Positive_regulation of Phosphorylation of Akt1 1 0.07 0.24 0.41
113 INT327727 Atp6v0a2 Negative_regulation of Gene_expression of Kit 1 0.05 0.83 0.41
114 INT276216 Binding of Akt1 and Ins1 2 0.03 2.61 0.4
115 INT231842 Pcdh8 Positive_regulation of Akt1 1 0.00 1.59 0.4
116 INT322409 Positive_regulation of OPRM1 Positive_regulation of Phosphorylation of Akt1 1 0.04 0 0.4
117 INT166155 Ccr9 Positive_regulation of Akt1 1 0.58 2.14 0.39
118 INT181441 Csf2 Positive_regulation of Cxcl12 1 0.02 1.69 0.39
119 INT148246 Binding of KITLG and Positive_regulation of Kit 1 0.04 0.43 0.38
120 INT148247 KITLG Positive_regulation of Kit 1 0.03 0.43 0.38
121 INT2428 Pag1 Regulation of Kitl 1 0.00 0.41 0.38
122 INT146611 Ins1 Positive_regulation of Phosphorylation of Akt1 9 0.23 4.34 0.37
123 INT281154 ITIH4 Positive_regulation of Cxcr4 1 0.09 0.71 0.37
124 INT281123 Binding of Cd4 and Cxcr4 1 0.24 0.92 0.37
125 INT281128 Cd4 Positive_regulation of Cxcr4 1 0.25 0.71 0.37
126 INT277353 VEGFA Regulation of Mtor 1 0.02 1.11 0.37
127 INT277354 Gene_expression of VEGFA Regulation of Mtor 1 0.02 1.1 0.37
128 INT226785 Angpt2 Positive_regulation of Localization of Lep 1 0.01 1.65 0.36
129 INT172213 Binding of BAX and BCL2L1 3 0.22 4.02 0.35
130 INT148243 Binding of Akt1 and Kit 1 0.03 0.44 0.35
131 INT122758 Positive_regulation of Helt Positive_regulation of Akt1 1 0.00 0.2 0.35
132 INT148240 Binding of Kit and Ret 1 0.24 0.44 0.35
133 INT288208 Binding of Mapk14 and Positive_regulation of Akt1 1 0.01 0.42 0.35
134 INT148241 Binding of Kit and Ntrk1 1 0.25 0.44 0.35
135 INT122756 Helt Positive_regulation of Akt1 1 0.00 0.2 0.35
136 INT309118 Dlat Positive_regulation of Positive_regulation of Akt1 1 0.03 0.32 0.34
137 INT155061 Stat3 Negative_regulation of Bax 1 0.22 3.71 0.34
138 INT249019 Gabrg1 Positive_regulation of Akt1 1 0.02 0 0.34
139 INT196820 Negative_regulation of Ppp1cc Positive_regulation of Akt1 1 0.00 0 0.34
140 INT44983 Ltc4s Positive_regulation of Rara 1 0.01 0.15 0.33
141 INT214377 Akt1 Regulation of Amph 1 0.15 0 0.33
142 INT273118 Bdnf Positive_regulation of Mtor 1 0.66 0 0.33
143 INT353362 amd Negative_regulation of Cxcr4 1 0.04 0.52 0.33
144 INT181893 TNF Regulation of ANGPT2 1 0.04 1.22 0.33
145 INT226716 Binding of Cxcr4 and Sdf2l1 2 0.30 1.42 0.32
146 INT214987 Binding of FANCC and Sigmar1 1 0.06 0.34 0.32
147 INT44985 KNG1 Positive_regulation of Rara 1 0.00 0.15 0.32
148 INT165580 Binding of Akt1 and Grin2b 1 0.02 0.2 0.32
149 INT322964 Binding of IL8 and Cxcl12 1 0.30 0.2 0.32
150 INT255740 Pik3r1 Positive_regulation of Akt1 5 0.24 2.42 0.31
151 INT303063 Akt1 Negative_regulation of Gene_expression of Syn1 1 0.09 0.45 0.31
152 INT165921 Tlr4 Positive_regulation of Akt1 1 0.16 0.75 0.31
153 INT165920 Negative_regulation of Tlr4 Positive_regulation of Akt1 1 0.13 0.75 0.31
154 INT150050 Mtor Positive_regulation of Rps6kb1 3 0.49 1.44 0.3
155 INT337085 Binding of Cxcr4 and Mif 1 0.21 1.89 0.3
156 INT148242 Binding of Kit and Gtf3a 1 0.04 0.34 0.3
157 INT281127 Tcf21 Positive_regulation of Gene_expression of Cxcr4 1 0.08 0.42 0.3
158 INT122575 Akt1 Positive_regulation of Phosphorylation of Nos3 4 0.37 3.89 0.29
159 INT211997 CORD1 Positive_regulation of Rara 1 0.01 0.68 0.29
160 INT132367 Lgals1 Positive_regulation of Akt1 1 0.22 0.13 0.28
161 INT317533 Akt1 Positive_regulation of Nos1 1 0.43 0 0.28
162 INT298348 ANGPT2 Positive_regulation of Phosphorylation of Stat3 1 0.18 0.14 0.28
163 INT333246 Binding of Cxcr4 and Cxcl12 3 0.34 0.99 0.27
164 INT172901 Binding of Bad and Bcl2l1 3 0.13 6.51 0.27
165 INT149322 Amph Positive_regulation of Akt1 1 0.39 0 0.27
166 INT254000 Regulation of Binding of Cxcr4 and Mif 1 0.29 0.56 0.27
167 INT223930 Binding of Akt1 and Pik3cb 1 0.07 0.35 0.26
168 INT258343 Binding of Aicda and Kit 1 0.06 0.57 0.26
169 INT223929 Negative_regulation of Binding of Akt1 and Pik3cb 1 0.08 0.36 0.26
170 INT303082 Akt1 Negative_regulation of Gene_expression of Mafk 1 0.20 0.37 0.26
171 INT308661 Akt1 Positive_regulation of Chuk 1 0.02 0.6 0.25
172 INT314047 THL Negative_regulation of Phosphorylation of Akt1 1 0.14 0.71 0.25
173 INT326094 Akt1 Positive_regulation of Gene_expression of Gopc 1 0.03 0.49 0.24
174 INT326092 Gene_expression of Akt1 Negative_regulation of Gopc 1 0.03 0.55 0.24
175 INT281133 Binding of Ccl2 and Cxcr4 1 0.06 0.63 0.24
176 INT326093 Akt1 Positive_regulation of Gopc 1 0.03 0.43 0.23
177 INT108842 RARA Positive_regulation of Gene_expression of GDF15 1 0.52 0.68 0.23
178 INT254351 Binding of ANGPT2 and TEK 1 0.04 0.87 0.22
179 INT323173 THRA Positive_regulation of Phosphorylation of Akt1 1 0.00 0 0.22
180 INT260844 NRP2 Positive_regulation of Akt1 1 0.00 0.73 0.22
181 INT116467 Vegfa Positive_regulation of Akt1 1 0.33 1.41 0.21
182 INT182606 Binding of MSH2 and MSH3 1 0.12 1.4 0.21
183 INT323174 DBT Positive_regulation of Phosphorylation of Akt1 1 0.01 0 0.21
184 INT116468 VEGFA Positive_regulation of Akt1 1 0.04 1.39 0.21
185 INT289356 Binding of Akt1 and Fgf2 1 0.03 0.82 0.21
186 INT309661 C5 Positive_regulation of Phosphorylation of Akt1 1 0.51 0.45 0.21
187 INT253991 Negative_regulation of Binding of Cxcl12 and Cxcr4 1 0.43 0.41 0.21
188 INT221237 Prkca Regulation of Phosphorylation of Akt1 1 0.01 0.28 0.2
189 INT239328 Hdl1 Regulation of Gene_expression of Kitl 1 0.08 1.86 0.2
190 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19
191 INT280270 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.08 1.81 0.19
192 INT224688 Pten Regulation of Akt1 1 0.04 1.12 0.19
193 INT280267 Tgfb1 Positive_regulation of Cxcr4 1 0.11 2.45 0.19
194 INT279965 STAT3 Regulation of Transcription of BCL2L1 1 0.10 2.31 0.19
195 INT334631 Igf1r Positive_regulation of Phosphorylation of Akt1 1 0.19 0.5 0.18
196 INT355504 ANGPT2 Positive_regulation of CYBB 1 0.01 0.81 0.18
197 INT303058 Akt1 Negative_regulation of Gene_expression of Syt1 1 0.21 0.43 0.18
198 INT333250 Binding of Cxcr7 and Cxcl12 1 0.19 1.39 0.18
199 INT221231 Pdpk1 Positive_regulation of Akt1 1 0.09 0.13 0.18
200 INT221244 Pdpk1 Positive_regulation of Phosphorylation of Akt1 1 0.09 0.13 0.18

Single Events

The table below shows the top 100 pain related interactions that have been reported for germ cell development. They are ordered first by their pain relevance and then by number of times they were reported in germ cell development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
2 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34
3 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43
4 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82
5 INT1726 Positive_regulation of Kitl 65 0.70 38.81 44.85
6 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81
7 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76
8 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53
9 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48
10 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39
11 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09
12 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67
13 INT83797 Gene_expression of Bcl2l1 124 0.77 94.55 22.39
14 INT96741 Gene_expression of Cxcr4 62 0.78 32.3 22.14
15 INT9750 Positive_regulation of Rara 39 0.66 12.44 15.83
16 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36
17 INT109304 Positive_regulation of Phosphorylation of Akt1 113 0.69 40.92 13.49
18 INT26534 Regulation of Akt1 34 0.61 14.47 11.86
19 INT15305 Positive_regulation of Mtor 51 0.67 8.28 11
20 INT20166 Negative_regulation of Mtor 32 0.56 10.64 10.25
21 INT99505 Gene_expression of Bcl2l1 42 0.77 33.12 10.15
22 INT222233 Gene_expression of Cxcl12 42 0.69 32.64 10.13
23 INT75137 Regulation of Akt1 74 0.48 37.89 9.7
24 INT149069 Positive_regulation of Cxcr4 24 0.68 12.21 9.54
25 INT102110 Positive_regulation of Gene_expression of Bax 42 0.67 35.77 9.51
26 INT15307 Regulation of Mtor 27 0.48 4.7 9.34
27 INT102106 Positive_regulation of Bax 48 0.67 30.62 9.28
28 INT120967 Negative_regulation of Phosphorylation of Akt1 47 0.57 23.67 8.98
29 INT104396 Positive_regulation of Positive_regulation of Akt1 44 0.55 14.78 8.69
30 INT126478 Gene_expression of Cxcl12 78 0.77 58.69 8.01
31 INT106522 Negative_regulation of Phosphorylation of Akt1 65 0.58 34.44 7.83
32 INT1664 Gene_expression of Kitl 30 0.65 13.63 7.47
33 INT103925 Negative_regulation of Positive_regulation of Akt1 32 0.58 15.19 7.39
34 INT102107 Negative_regulation of Gene_expression of Bax 30 0.57 29.48 7.33
35 INT126748 Positive_regulation of Positive_regulation of Akt1 26 0.55 11.15 7.08
36 INT11652 Gene_expression of Rara 30 0.58 24.96 6.98
37 INT98837 Positive_regulation of Bax 72 0.61 63.14 6.41
38 INT99506 Negative_regulation of Bcl2l1 25 0.58 15.7 6.09
39 INT117721 Positive_regulation of Gene_expression of Akt1 22 0.69 6.26 6.08
40 INT13352 Regulation of Kitl 11 0.45 3.91 6.07
41 INT114882 Positive_regulation of Gene_expression of Akt1 45 0.69 21.29 6.06
42 INT126481 Gene_expression of Cxcr4 69 0.77 34.99 6
43 INT253974 Binding of Cxcr4 22 0.47 12.26 5.95
44 INT96744 Positive_regulation of Gene_expression of Cxcr4 14 0.68 7.92 5.75
45 INT136309 Positive_regulation of Cxcl12 24 0.62 12.45 5.58
46 INT7524 Localization of Kitl 9 0.74 3.45 5.49
47 INT145929 Regulation of Bax 20 0.60 18.12 5.35
48 INT87420 Gene_expression of BCL2L1 56 0.75 48.84 5.32
49 INT24080 Negative_regulation of Mtor 64 0.37 41.56 5.19
50 INT25832 Negative_regulation of Kitl 9 0.43 3.59 5.07
51 INT109513 Positive_regulation of Gene_expression of Bax 37 0.67 29.52 5.06
52 INT23611 Gene_expression of Mtor 23 0.66 3.57 5.02
53 INT99507 Positive_regulation of Bcl2l1 17 0.69 9.23 4.97
54 INT58766 Gene_expression of ANGPT2 41 0.67 21.65 4.82
55 INT116614 Positive_regulation of Gene_expression of Bcl2l1 12 0.67 11.39 4.68
56 INT134657 Localization of Akt1 37 0.68 11.58 4.62
57 INT122569 Negative_regulation of Gene_expression of Akt1 34 0.54 17.15 4.44
58 INT99504 Negative_regulation of Bax 19 0.56 8.89 4.44
59 INT1209 Binding of Kitl 14 0.37 6.72 4.3
60 INT10374 Gene_expression of RARA 39 0.75 22.59 4.28
61 INT83794 Positive_regulation of Gene_expression of Bcl2l1 26 0.69 16.89 4.28
62 INT83798 Negative_regulation of Gene_expression of Bcl2l1 28 0.58 20.26 4.21
63 INT90890 Positive_regulation of RARA 25 0.67 9.32 4.2
64 INT75136 Binding of Akt1 27 0.27 8.81 4.15
65 INT88278 Binding of Kit 33 0.37 24.45 4.13
66 INT139898 Negative_regulation of Positive_regulation of Akt1 15 0.42 4.66 4.06
67 INT83796 Regulation of Gene_expression of Bcl2l1 10 0.61 7.85 4.05
68 INT123752 Regulation of Bax 19 0.60 16.45 4
69 INT112692 Localization of Bax 31 0.80 20.97 3.98
70 INT101857 Negative_regulation of BCL2L1 22 0.57 23.56 3.95
71 INT95423 Negative_regulation of Bcl2l1 26 0.41 21.66 3.81
72 INT54886 Negative_regulation of ANGPT2 25 0.42 9.33 3.79
73 INT253983 Binding of Cxcl12 8 0.43 5.33 3.71
74 INT132223 Negative_regulation of Negative_regulation of Akt1 6 0.42 2.75 3.66
75 INT136692 Localization of Akt1 12 0.78 2.14 3.65
76 INT124185 Negative_regulation of Kit 57 0.59 35.43 3.61
77 INT88255 Regulation of Positive_regulation of Kitl 2 0.00 1.72 3.47
78 INT122997 Phosphorylation of Rps6kb1 46 0.72 9.92 3.43
79 INT157687 Regulation of Gene_expression of Akt1 9 0.62 4.96 3.27
80 INT96740 Transcription of Cxcr4 6 0.68 2.96 3.12
81 INT86245 Positive_regulation of Bcl2l1 15 0.46 12.67 3.11
82 INT117720 Negative_regulation of Gene_expression of Akt1 11 0.37 2.33 3.08
83 INT91890 Positive_regulation of Kit 36 0.50 25.44 3.06
84 INT21610 Positive_regulation of ANGPT2 23 0.41 13.28 3.03
85 INT228677 Negative_regulation of Phosphorylation of Rps6kb1 24 0.51 3.88 2.97
86 INT181386 Positive_regulation of Cxcl12 12 0.69 15.35 2.84
87 INT41721 Negative_regulation of MTOR 40 0.58 32.49 2.83
88 INT248177 Localization of Cxcr4 17 0.79 4.87 2.82
89 INT117715 Regulation of Phosphorylation of Akt1 15 0.51 3.23 2.78
90 INT228678 Phosphorylation of Mtor 15 0.78 3.18 2.76
91 INT99508 Regulation of Bcl2l1 12 0.61 10.44 2.71
92 INT156016 Binding of BCL2L1 10 0.36 7.42 2.64
93 INT253982 Positive_regulation of Binding of Cxcl12 1 0.45 3.85 2.6
94 INT214355 Binding of Akt1 13 0.36 3.72 2.59
95 INT149068 Regulation of Cxcr4 3 0.44 3.77 2.46
96 INT110231 Regulation of Gene_expression of Cxcr4 7 0.44 3.18 2.44
97 INT130638 Regulation of Cxcl12 6 0.34 2.91 2.44
98 INT26696 Gene_expression of Hils1 4 0.21 1.18 2.38
99 INT102146 Phosphorylation of Bax 4 0.66 3.48 2.35
100 INT97748 Positive_regulation of BCL2L1 12 0.67 9.83 2.26
101 INT91836 Negative_regulation of Gene_expression of BCL2L1 9 0.49 8.59 2.25
102 INT151449 Negative_regulation of Gene_expression of Kit 18 0.45 12.05 2.23
103 INT83799 Phosphorylation of Bcl2l1 8 0.82 7.86 2.23
104 INT138286 Regulation of Positive_regulation of Akt1 13 0.45 4.93 2.22
105 INT102752 Positive_regulation of Gene_expression of BCL2L1 14 0.67 13.8 2.19
106 INT13368 Binding of Hils1 5 0.23 0.46 2.14
107 INT222230 Positive_regulation of Gene_expression of Cxcl12 11 0.59 5.26 2.13
108 INT154970 Localization of Bax 15 0.74 11.12 2.11
109 INT55470 Regulation of Mtor 16 0.24 12.51 2.07
110 INT101645 Regulation of Gene_expression of Bcl2l1 8 0.36 5.27 2.05
111 INT36293 Gene_expression of Mtor 24 0.25 14.5 2.04
112 INT297679 Positive_regulation of Gene_expression of Cxcl12 6 0.69 8.02 2.02
113 INT126060 Negative_regulation of Gene_expression of Cxcr4 9 0.42 3.14 1.99
114 INT98836 Transcription of Bax 6 0.69 5.04 1.96
115 INT99572 Localization of Kit 13 0.75 5.23 1.95
116 INT226637 Negative_regulation of Cxcr4 41 0.48 24.42 1.91
117 INT134442 Transcription of Bax 14 0.67 7.6 1.9
118 INT135540 Negative_regulation of Bax 16 0.48 11.8 1.89
119 INT134443 Binding of Bax 10 0.47 5.62 1.84
120 INT140175 Regulation of Kit 23 0.62 8.59 1.79
121 INT142236 Regulation of Phosphorylation of Akt1 13 0.61 5.02 1.75
122 INT104883 Positive_regulation of Positive_regulation of Bax 4 0.45 4.05 1.74
123 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73
124 INT126476 Positive_regulation of Cxcr4 25 0.69 19.01 1.72
125 INT253972 Positive_regulation of Positive_regulation of Cxcl12 1 0.45 3.22 1.71
126 INT86909 Negative_regulation of MSH2 9 0.41 12.65 1.7
127 INT165332 Negative_regulation of Negative_regulation of Akt1 5 0.42 3.27 1.7
128 INT192092 Positive_regulation of Gene_expression of Rara 8 0.32 4.41 1.68
129 INT116022 Positive_regulation of Positive_regulation of RARA 3 0.11 0.94 1.68
130 INT97749 Regulation of BCL2L1 10 0.41 9.72 1.65
131 INT117714 Regulation of Positive_regulation of Akt1 3 0.61 0.44 1.61
132 INT107992 Gene_expression of MSH2 39 0.78 37.09 1.6
133 INT222227 Localization of Cxcl12 5 0.64 1.61 1.59
134 INT106413 Transcription of Bcl2l1 8 0.53 3.35 1.52
135 INT254252 Localization of Cxcl12 9 0.76 7.17 1.49
136 INT182629 Binding of Cxcr4 12 0.36 5.24 1.47
137 INT146785 Positive_regulation of Localization of Bax 7 0.69 6.16 1.47
138 INT67457 Binding of Rara 12 0.24 8.28 1.45
139 INT41719 Gene_expression of MTOR 27 0.77 19.43 1.44
140 INT109512 Negative_regulation of Gene_expression of Bax 12 0.42 8.04 1.44
141 INT151450 Positive_regulation of Gene_expression of Kit 23 0.69 13.11 1.43
142 INT166764 Localization of Mtor 2 0.75 1.28 1.42
143 INT316075 Negative_regulation of Negative_regulation of Kitl 1 0.06 0.42 1.41
144 INT121307 Gene_expression of Ercc1 4 0.73 12.69 1.37
145 INT105881 Phosphorylation of Bcl2l1 3 0.51 1.99 1.31
146 INT112695 Negative_regulation of Protein_catabolism of Bax 3 0.36 1.72 1.3
147 INT214983 Positive_regulation of FANCC 11 0.15 1.81 1.29
148 INT41698 Localization of Hils1 3 0.16 0.54 1.29
149 INT81400 Binding of RARA 25 0.36 12.93 1.27
150 INT154969 Positive_regulation of Localization of Bax 4 0.64 3.42 1.27
151 INT18947 Negative_regulation of Hils1 3 0.04 1.11 1.27
152 INT228670 Negative_regulation of Rps6kb1 12 0.38 5.27 1.21
153 INT228671 Negative_regulation of Phosphorylation of Mtor 8 0.50 1.77 1.2
154 INT112693 Protein_catabolism of Bax 5 0.74 3.17 1.2
155 INT23415 Regulation of Hils1 2 0.27 0.29 1.18
156 INT141189 Negative_regulation of Transcription of Bax 1 0.41 1.42 1.14
157 INT182985 Transcription of RARA 9 0.60 3.52 1.12
158 INT207203 Transcription of Akt1 6 0.67 3.73 1.1
159 INT149553 Negative_regulation of Transcription of Cxcr4 2 0.36 0.29 1.06
160 INT135806 Regulation of Bcl2l1 10 0.44 7.21 1.05
161 INT211294 Binding of Cxcl12 4 0.45 2.89 1.05
162 INT191050 Positive_regulation of Negative_regulation of Akt1 6 0.31 1.82 1.03
163 INT151774 Positive_regulation of Mtor 38 0.45 20.15 1.01
164 INT164863 Positive_regulation of Phosphorylation of Bcl2l1 1 0.31 0.57 1.01
165 INT232636 Positive_regulation of Binding of Kit 4 0.39 1.98 0.98
166 INT69758 Negative_regulation of Positive_regulation of Rara 2 0.32 0.24 0.97
167 INT94393 Localization of ANGPT2 8 0.17 5.02 0.96
168 INT253976 Positive_regulation of Positive_regulation of Cxcr4 1 0.46 1.19 0.96
169 INT175507 Regulation of Gene_expression of Bax 13 0.50 10.91 0.95
170 INT106746 Gene_expression of Mtap7 1 0.39 2.09 0.95
171 INT134660 Positive_regulation of Localization of Akt1 10 0.32 6.33 0.94
172 INT156015 Negative_regulation of Protein_catabolism of BCL2L1 1 0.42 1.23 0.93
173 INT156014 Protein_catabolism of BCL2L1 1 0.64 1.23 0.93
174 INT163508 Regulation of Gene_expression of Akt1 3 0.45 1.65 0.92
175 INT222231 Transcription of Cxcl12 4 0.55 2.25 0.91
176 INT156017 Positive_regulation of Binding of BCL2L1 1 0.49 1.21 0.91
177 INT226691 Positive_regulation of Gene_expression of Cxcr4 14 0.57 7.9 0.9
178 INT192090 Localization of Rara 6 0.46 4.15 0.89
179 INT36494 Positive_regulation of Hils1 2 0.15 0.88 0.88
180 INT48251 Regulation of Positive_regulation of Rara 2 0.33 0 0.88
181 INT149552 Negative_regulation of Positive_regulation of Cxcr4 1 0.09 0 0.88
182 INT56972 Regulation of ANGPT2 6 0.44 3.48 0.86
183 INT142122 Regulation of Gene_expression of Bmp4 5 0.43 2.69 0.86
184 INT120366 Negative_regulation of Rara 2 0.35 0.15 0.86
185 INT48250 Regulation of Rara 3 0.29 2.47 0.83
186 INT48249 Positive_regulation of Positive_regulation of Rara 2 0.26 0 0.83
187 INT58765 Positive_regulation of Gene_expression of ANGPT2 11 0.38 8.2 0.81
188 INT144697 Regulation of Gene_expression of Bax 8 0.37 9.5 0.81
189 INT210247 Positive_regulation of Bmp4 6 0.65 4.36 0.8
190 INT212109 Localization of RARA 5 0.65 3.17 0.79
191 INT271917 Phosphorylation of Mtor 11 0.13 6.76 0.78
192 INT174069 Positive_regulation of Rps6kb1 14 0.61 3.7 0.77
193 INT63912 Regulation of Negative_regulation of Kitl 1 0.00 0.59 0.77
194 INT167677 Localization of Cxcr4 8 0.58 6.61 0.76
195 INT92142 Binding of MSH2 5 0.46 5.64 0.75
196 INT151170 Regulation of Regulation of Akt1 2 0.45 3.28 0.73
197 INT122999 Gene_expression of Rps6kb1 16 0.67 3.45 0.71
198 INT101209 Gene_expression of Wt1 19 0.72 25.77 0.7
199 INT213923 Positive_regulation of MTOR 16 0.65 9.28 0.7
200 INT131567 Negative_regulation of Positive_regulation of Bcl2l1 1 0.41 0.66 0.7
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