GO:0007369

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Name gastrulation
Categary Process
Go Slim No
Go Link GO:0007369
Unique Molecular Interactions 371
Total Molecular Interactions 508
Total Single Events 3347
Pain Genes Associated 32

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for gastrulation. They are ordered first by their pain relevance and then by number of times they were reported for gastrulation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT166388 Binding of Gnb2l1 and Mapk1 1 0.49 0.49 1.21
3 INT75486 Binding of Tgfbr1 and Tgfbr2 1 0.10 1.94 1.02
4 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
5 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
6 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
7 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
8 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
9 INT166386 Mapk1 Regulation of Gene_expression of Gnb2l1 1 0.46 0.25 0.7
10 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
11 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
12 INT166387 Binding of Gnb2l1 and Mdk 1 0.30 0.24 0.61
13 INT166385 Binding of Araf and Gnb2l1 1 0.23 0.24 0.6
14 INT343913 Binding of FOS and Smad3 1 0.19 0.92 0.54
15 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
16 INT244050 Binding of Gnb2l1 and Prkca 1 0.01 0 0.45
17 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43
18 INT237453 Binding of STAR and MESP1 1 0.00 0.47 0.42
19 INT17059 Binding of DLD and Oxt 1 0.03 0.22 0.41
20 INT75489 Binding of SGCG and Tgfbr2 1 0.23 0.83 0.41
21 INT75487 Binding of TGFB1 and Tgfbr2 1 0.31 0.83 0.41
22 INT91814 Binding of TNF and TP53 1 0.14 2.2 0.32
23 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
24 INT166396 IFI27 Regulation of Gene_expression of TP53 1 0.19 0.41 0.31
25 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 0.01 1.23 0.3
26 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3
27 INT163761 MDM2 Positive_regulation of Gene_expression of TP53 1 0.40 0.86 0.3
28 INT93833 Binding of Fos and Srf 1 0.00 0 0.3
29 INT150351 Binding of EXT1 and MMP12 1 0.04 3.68 0.29
30 INT137023 Gene_expression of SMAD2 Negative_regulation of Gene_expression of Acta2 1 0.00 0.43 0.29
31 INT93832 Binding of Elk1 and Srf 1 0.00 0 0.29
32 INT166952 LYRM4 Positive_regulation of Gene_expression of TP53 1 0.05 0.75 0.28
33 INT286042 Binding of Tp53 and Wwox 1 0.04 2.05 0.28
34 INT216127 EGR1 Regulation of Transcription of TP53 1 0.06 0.21 0.28
35 INT302837 Binding of TNFRSF10D and Trp53 1 0.01 0.98 0.28
36 INT306267 Binding of INCENP and TP53 1 0.02 0.83 0.27
37 INT216128 EGR1 Regulation of TP53 1 0.11 0.21 0.27
38 INT352931 Prkaca Regulation of TP53 1 0.13 1.01 0.26
39 INT352930 Prkaca Regulation of Phosphorylation of TP53 1 0.13 1.02 0.26
40 INT182325 TP53 Negative_regulation of Transcription of Birc5 1 0.01 1.34 0.26
41 INT172975 Trp53 Positive_regulation of Cdkn1a 1 0.03 1.35 0.26
42 INT352893 PTGDS Regulation of TP53 1 0.16 1.02 0.26
43 INT125516 TP53 Regulation of GDF15 1 0.10 0.47 0.26
44 INT337086 Mif Negative_regulation of Localization of Trp53 1 0.16 1.64 0.25
45 INT337091 Mif Negative_regulation of Positive_regulation of Trp53 1 0.16 1.64 0.25
46 INT156879 Gene_expression of TP53 Negative_regulation of Positive_regulation of PDF 1 0.45 0.9 0.24
47 INT181900 TP53 Negative_regulation of Gene_expression of NOS1 1 0.03 0.94 0.24
48 INT156881 TP53 Positive_regulation of Positive_regulation of PDF 1 0.49 0.89 0.24
49 INT229177 IFRD1 Regulation of TP53 1 0.13 0.68 0.23
50 INT226902 Padi3 Regulation of Trp53 1 0.06 0.69 0.22
51 INT229178 TP53 Regulation of ICAM1 1 0.07 0.9 0.21
52 INT309513 Binding of Xrcc6 and Htt 1 0.30 3.69 0.21
53 INT39567 Txnrd1 Regulation of Localization of Il1f5 1 0.04 0.18 0.21
54 INT156882 Binding of TP53 and PDF 1 0.39 0.77 0.21
55 INT156880 TP53 Positive_regulation of Gene_expression of PDF 1 0.49 0.75 0.21
56 INT234992 Car2 Positive_regulation of Jup 1 0.02 0.27 0.2
57 INT210887 Sst Positive_regulation of Gene_expression of Trp53 1 0.33 0.93 0.2
58 INT310498 Gene_expression of Neurog2 Positive_regulation of Positive_regulation of Eomes 1 0.20 0.42 0.19
59 INT193787 Positive_regulation of CXCR4 Positive_regulation of Positive_regulation of TP53 1 0.03 0.71 0.19
60 INT142853 Binding of TP53 and WISP2 1 0.33 1.43 0.19
61 INT333449 Binding of SMAD2 and SMAD4 1 0.23 0 0.17
62 INT179846 Il11 Regulation of Positive_regulation of Rps6 1 0.04 0.07 0.17
63 INT102804 NFKB1 Regulation of TP53 1 0.35 0.77 0.17
64 INT102803 NFKB1 Regulation of Gene_expression of TP53 1 0.35 0.77 0.17
65 INT91812 Binding of FASLG and TP53 1 0.04 1.1 0.16
66 INT91811 Binding of FAS and TP53 1 0.21 1.1 0.16
67 INT333447 Binding of SMAD2 and RXRA 1 0.04 0 0.16
68 INT266377 Binding of S100a11 and Trp53 1 0.02 0.89 0.15
69 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
70 INT103557 Binding of ERCC2 and TP53 1 0.40 1 0.13
71 INT201762 JUP Regulation of Gene_expression of Ccnd1 1 0.03 0.8 0.13
72 INT132148 LTF Positive_regulation of TP53 1 0.44 0.56 0.13
73 INT201791 JUP Regulation of Gene_expression of Myc 1 0.49 0.8 0.13
74 INT103561 Binding of TP53 and Mc1r 1 0.03 1 0.13
75 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
76 INT261690 Binding of GSC and TCF23 1 0.10 0 0.12
77 INT172976 Mras Regulation of Gene_expression of Smad4 1 0.00 0.83 0.12
78 INT317162 Binding of Bdnf and Htt 1 0.51 0.2 0.12
79 INT83370 Binding of HRAS and TP53 1 0.30 0.59 0.11
80 INT319315 Binding of Ap2a2 and Htt 1 0.28 0.64 0.11
81 INT266386 Binding of S100a1 and Trp53 1 0.03 0.64 0.1
82 INT316823 Sparc Positive_regulation of Phosphorylation of Smad2 1 0.44 0.49 0.1
83 INT193782 Binding of TP53 and SDF2L1 1 0.00 0.67 0.1
84 INT262522 Binding of Trp53 and Foxo4 1 0.05 0.7 0.1
85 INT310743 TP53 Regulation of BAX 1 0.09 1.11 0.1
86 INT326126 Binding of S100A1 and TP53 1 0.04 1.34 0.09
87 INT125089 Binding of HLA-B and TDGF1 1 0.24 0.18 0.09
88 INT302979 Binding of Gnb2l1 and Smpd2 1 0.07 0.71 0.09
89 INT352611 Trp53 Negative_regulation of Localization of Gli1 1 0.23 1.2 0.09
90 INT302168 YWHAQ Regulation of TP53 1 0.01 0.41 0.09
91 INT265466 CSPG4 Regulation of Phosphorylation of TP53 1 0.09 0.15 0.09
92 INT246625 Sirt1 Positive_regulation of Negative_regulation of Trp53 1 0.10 0.96 0.08
93 INT38206 Acr Negative_regulation of Txnrd1 1 0.20 0.08 0.08
94 INT266394 Binding of S100a4 and Trp53 1 0.03 0.59 0.08
95 INT216130 SRF Positive_regulation of Gene_expression of EGR1 1 0.49 0.32 0.07
96 INT339111 Binding of ERBB2 and JUP 1 0.38 0.62 0.07
97 INT266390 Binding of S100a6 and Trp53 1 0.04 0.51 0.07
98 INT216129 SRF Positive_regulation of Gene_expression of FOS 1 0.28 0.32 0.07
99 INT339108 Binding of ESR1 and JUP 1 0.38 0.62 0.07
100 INT349914 Binding of Cdh1 and Jup 1 0.11 0.47 0.07
101 INT76965 Mpo Negative_regulation of DLD 1 0.26 0.91 0.07
102 INT245296 Trp53 Regulation of Gadd45a 1 0.05 0.43 0.07
103 INT266398 Binding of S100b and Trp53 1 0.06 0.92 0.07
104 INT302143 TP53 Regulation of Positive_regulation of CASP3 1 0.01 0.69 0.06
105 INT311916 Smad3 Negative_regulation of Gene_expression of Mmp13 1 0.12 0.27 0.06
106 INT302155 TP53 Regulation of Positive_regulation of CASP9 1 0.02 0.7 0.06
107 INT311906 Binding of Smad4 and Insrr 1 0.00 0.18 0.06
108 INT234968 IgG Negative_regulation of Jup 1 0.02 1.09 0.06
109 INT204074 Tp53 Positive_regulation of Cdkn1b 1 0.00 0.59 0.06
110 INT140291 ROS1 Positive_regulation of TP53 1 0.52 1.27 0.06
111 INT265459 Phosphorylation of TP53 Positive_regulation of Localization of CASP9 1 0.17 1.16 0.05
112 INT353284 Prdx2 Negative_regulation of Gene_expression of Smad2 1 0.16 0.07 0.05
113 INT352618 Tpt1 Regulation of Trp53 1 0.06 0.54 0.05
114 INT286768 Binding of Trp53 and Tusc2 1 0.07 1.1 0.05
115 INT352621 Gli1 Negative_regulation of Trp53 1 0.32 0.56 0.05
116 INT181601 Binding of TP53 and WT1 1 0.30 0.9 0.05
117 INT265454 Phosphorylation of TP53 Positive_regulation of CASP9 1 0.17 1.16 0.05
118 INT317181 Binding of Htt and Uts2r 1 0.04 0 0.05
119 INT310321 DLD Negative_regulation of COQ10A 1 0.01 0.06 0.05
120 INT345181 Gpr87 Regulation of Trp53 1 0.01 0.42 0.05
121 INT193788 ITIH4 Regulation of Phosphorylation of TP53 1 0.07 0.45 0.05
122 INT352612 Trp53 Negative_regulation of Cd44 1 0.24 1.01 0.04
123 INT348022 Binding of Jun and Trp53 1 0.07 0.46 0.04
124 INT319558 Positive_regulation of Creb1 Regulation of Srf 1 0.31 0.06 0.04
125 INT172214 BAX Positive_regulation of TP53 1 0.09 0.37 0.04
126 INT329230 Negative_regulation of ATIC Positive_regulation of Trp53 1 0.00 0.58 0.04
127 INT319559 Creb1 Regulation of Srf 1 0.28 0.06 0.04
128 INT353290 Binding of Smad2 and Smad4 1 0.20 0.08 0.04
129 INT353294 Binding of Smad2 and Smad3 1 0.15 0.08 0.04
130 INT329228 ATIC Positive_regulation of Trp53 1 0.01 0.58 0.04
131 INT352619 Bcl2l12 Negative_regulation of Trp53 1 0.27 0.94 0.04
132 INT353295 Binding of Smad3 and Smad4 1 0.17 0.08 0.04
133 INT352613 Binding of Trp53 and Bcl2l12 1 0.23 0.94 0.04
134 INT306527 Binding of Htt and Aifm1 1 0.20 0.82 0.04
135 INT353289 Prdx2 Negative_regulation of Positive_regulation of Smad2 1 0.18 0.17 0.04
136 INT353293 Prdx2 Negative_regulation of Localization of Smad2 1 0.16 0 0.04
137 INT170457 RASGRP1 Regulation of TP53 1 0.02 0.58 0.04
138 INT201726 Mapk8 Positive_regulation of Positive_regulation of Trp53 1 0.00 0.41 0.04
139 INT260267 Binding of TFAM and TP53 2 0.37 2.1 0.03
140 INT311904 Smad2 Positive_regulation of Gene_expression of Smad1 1 0.13 0.44 0.03
141 INT355036 CKAP4 Regulation of Positive_regulation of TP53 1 0.08 0.4 0.03
142 INT319218 Bmpr2 Negative_regulation of Smad2 1 0.17 0.12 0.03
143 INT317161 Htt Regulation of Transcription of Bdnf 1 0.48 0.41 0.03
144 INT266903 Binding of Sod2 and Trp53 1 0.05 0 0.03
145 INT211873 TP53 Positive_regulation of Transcription of CD40 1 0.03 1.44 0.03
146 INT234625 TP53 Positive_regulation of IGFBP3 1 0.29 0.74 0.03
147 INT353286 Prdx2 Positive_regulation of Phosphorylation of Smad2 1 0.24 0.06 0.03
148 INT352624 Trp53 Negative_regulation of CEL 1 0.01 1.01 0.03
149 INT280263 Binding of Smad4 and Proc 1 0.00 1.26 0.03
150 INT265464 CSPG4 Regulation of Gene_expression of TP53 1 0.09 0.23 0.03
151 INT254852 Binding of Col7a1 and Smad3 1 0.01 0.57 0.03
152 INT314686 TP53 Regulation of Gene_expression of MDM2 1 0.21 0.96 0.03
153 INT229098 Binding of TP53 and IER3 1 0.01 1.47 0.03
154 INT314677 TP53 Regulation of Positive_regulation of CDKN2A 1 0.27 0.97 0.03
155 INT276389 Binding of Trp53 and KRT20 1 0.01 0.97 0.03
156 INT302134 TP53 Positive_regulation of Transcription of CDKN1A 1 0.04 0.28 0.03
157 INT200311 Htt Positive_regulation of Rest 1 0.05 0.75 0.03
158 INT314690 TP53 Regulation of Gene_expression of ZBTB7A 1 0.33 0.97 0.03
159 INT211872 TP53 Positive_regulation of CD40 1 0.03 1.44 0.03
160 INT242015 Binding of Mdm2 and Trp53 3 0.16 5.74 0
161 INT192044 Binding of DSP and Jup 2 0.24 2.39 0
162 INT234995 Binding of CDH16 and Jup 1 0.00 0.27 0
163 INT352615 Binding of Mdm4 and Trp53 1 0.30 1.36 0
164 INT269943 Sox17 Regulation of Binding of Smad3 1 0.37 0.12 0
165 INT254849 Negative_regulation of Rhoa Positive_regulation of Phosphorylation of Smad3 1 0.11 0.45 0
166 INT304029 Binding of PTEN and TP53 1 0.35 0.62 0
167 INT315395 Regulation of Binding of IFNA1 and Tp53 1 0.00 0.46 0
168 INT304020 AR Regulation of TP53 1 0.24 1.11 0
169 INT315221 Tpt1 Regulation of Positive_regulation of Trp53 1 0.33 1.04 0
170 INT203901 HIVEP1 Positive_regulation of Gene_expression of TP53 1 0.04 0.86 0
171 INT269915 Binding of Smad2 and Sox17 1 0.21 0.07 0
172 INT132849 Homer1 Regulation of Srf 1 0.01 0.15 0
173 INT232006 Binding of Trp53 and Tsp1 1 0.06 0.75 0
174 INT333685 Binding of Trp53 and Hdac1 1 0.26 0.55 0
175 INT333688 Trp53 Positive_regulation of Bcl2 1 0.45 2.51 0
176 INT269937 Binding of Smad3 and Mgst1 1 0.09 0 0
177 INT304022 Binding of PIK3CG and TP53 1 0.10 0.72 0
178 INT333690 Hr Negative_regulation of Transcription of Trp53 1 0.23 0.51 0
179 INT217776 TP53 Regulation of MITF 1 0.00 1.28 0
180 INT188067 Rps6kb1 Regulation of Rps6 1 0.10 0.1 0
181 INT334322 Binding of RB1 and TP53 1 0.34 2 0
182 INT342007 Mta1 Regulation of Trp53 1 0.15 0.15 0
183 INT218669 Olr811 Negative_regulation of Phosphorylation of Smad2 1 0.01 0.18 0
184 INT121179 Binding of Htt and Rest 1 0.07 0.45 0
185 INT179095 Myc Positive_regulation of Gene_expression of Trp53 1 0.43 0.83 0
186 INT315397 Binding of IFNA1 and Tp53 1 0.00 0.43 0
187 INT333689 Hr Positive_regulation of Protein_catabolism of Trp53 1 0.25 1.71 0
188 INT345489 TP53 Positive_regulation of PMAIP1 1 0.05 0.6 0
189 INT269919 Sox17 Negative_regulation of Binding of Smad3 1 0.36 0 0
190 INT286044 Wwox Positive_regulation of Tp53 1 0.05 0.63 0
191 INT347162 MDM2 Negative_regulation of TP53 1 0.02 1.09 0
192 INT190632 Binding of Srf and Yy1 1 0.20 0.14 0
193 INT337915 Tgfbr1 Positive_regulation of Negative_regulation of Smad2 1 0.05 0.15 0
194 INT235645 TP53 Regulation of EPHA2 1 0.10 0.97 0
195 INT241256 TP53 Regulation of OPCML 1 0.12 1.31 0
196 INT234969 Jup Regulation of Gene_expression of Dsp 1 0.01 0.54 0
197 INT305542 Binding of Rb1 and Trp53 1 0.00 0.9 0
198 INT352625 Trp53 Regulation of CEL 1 0.00 0.71 0
199 INT309515 Xrcc6 Regulation of Gene_expression of Htt 1 0.32 0.08 0
200 INT269948 Sox17 Positive_regulation of Gene_expression of Ccnd1 1 0.61 0.19 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for gastrulation. They are ordered first by their pain relevance and then by number of times they were reported in gastrulation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
2 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
3 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
4 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
5 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
6 INT159116 Gene_expression of Gnb2l1 12 0.77 2.79 9.49
7 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
8 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
9 INT166383 Positive_regulation of Gene_expression of Gnb2l1 1 0.69 2.19 7.02
10 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
11 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
12 INT159115 Negative_regulation of Gene_expression of Gnb2l1 3 0.42 1.33 5.59
13 INT17056 Gene_expression of DLD 37 0.57 13.15 5.47
14 INT127112 Phosphorylation of Smad2 19 0.80 11.01 5.36
15 INT60585 Regulation of TP53 59 0.59 54.55 5.21
16 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
17 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
18 INT159122 Positive_regulation of Gnb2l1 8 0.69 2.2 4.61
19 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
20 INT57157 Gene_expression of TDGF1 5 0.75 3.97 4.02
21 INT75485 Gene_expression of Tgfbr2 10 0.57 10.98 3.76
22 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
23 INT87314 Gene_expression of Htt 112 0.78 55.82 3.03
24 INT12796 Binding of DLD 20 0.36 6.71 3.02
25 INT8103 Binding of TP53 46 0.44 40.2 2.96
26 INT7142 Positive_regulation of DLD 22 0.60 7.69 2.76
27 INT166381 Negative_regulation of Gnb2l1 1 0.43 0.73 2.68
28 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
29 INT4114 Gene_expression of Srf 9 0.70 6.11 2.63
30 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51
31 INT127113 Positive_regulation of Phosphorylation of Smad2 1 0.68 2.38 2.51
32 INT53447 Negative_regulation of DLD 17 0.54 12.9 2.48
33 INT55952 Transcription of TP53 16 0.61 12.14 2.36
34 INT159117 Regulation of Gene_expression of Gnb2l1 3 0.56 0.5 2.36
35 INT194504 Gene_expression of Smad2 27 0.65 7.45 2.25
36 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98
37 INT10447 Negative_regulation of Srf 3 0.40 0.95 1.98
38 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
39 INT107178 Gene_expression of Smad4 12 0.65 9.85 1.92
40 INT65855 Localization of TP53 18 0.76 17.08 1.89
41 INT113345 Positive_regulation of Phosphorylation of TP53 8 0.66 6.11 1.8
42 INT159120 Protein_catabolism of Gnb2l1 1 0.26 0.37 1.79
43 INT64233 Regulation of Trp53 35 0.62 27.11 1.53
44 INT127115 Regulation of Phosphorylation of Smad2 1 0.60 1.74 1.53
45 INT120004 Transcription of Tp53 8 0.72 4.92 1.48
46 INT255251 Negative_regulation of Smad2 12 0.32 5.69 1.44
47 INT101990 Negative_regulation of Positive_regulation of TP53 5 0.33 3.69 1.42
48 INT162469 Positive_regulation of Protein_catabolism of TP53 5 0.52 5.48 1.42
49 INT172953 Binding of Trp53 33 0.37 20.76 1.41
50 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41
51 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41
52 INT145221 Binding of Tp53 10 0.37 8.59 1.37
53 INT129619 Phosphorylation of Smad2 34 0.61 11.6 1.34
54 INT333924 Positive_regulation of TDGF1 1 0.02 1.03 1.24
55 INT174156 Localization of Trp53 16 0.72 13.52 1.18
56 INT116436 Negative_regulation of Phosphorylation of TP53 2 0.40 0.94 1.16
57 INT333920 Negative_regulation of Gene_expression of TDGF1 1 0.02 0.89 1.16
58 INT134661 Negative_regulation of Tp53 11 0.43 10.91 1.13
59 INT237456 Gene_expression of MESP1 1 0.03 1.33 1.12
60 INT184720 Negative_regulation of Smad3 8 0.55 5.23 1.1
61 INT108997 Localization of Htt 28 0.77 3.76 1.07
62 INT10448 Positive_regulation of Srf 3 0.47 0.89 1.03
63 INT135032 Negative_regulation of SRF 1 0.49 0 1.03
64 INT97052 Transcription of Trp53 12 0.64 6.52 1.01
65 INT242171 Protein_catabolism of JUP 4 0.96 0.91 1.01
66 INT254875 Positive_regulation of Htt 10 0.47 4.07 0.96
67 INT333922 Negative_regulation of TDGF1 1 0.02 0.91 0.96
68 INT61613 Regulation of DLD 6 0.34 2.96 0.92
69 INT218696 Negative_regulation of Phosphorylation of Smad2 3 0.42 4.36 0.92
70 INT26531 Regulation of Srf 3 0.18 0.62 0.9
71 INT140794 Gene_expression of Smad3 22 0.64 9.41 0.83
72 INT154886 Gene_expression of Htt 18 0.76 15.51 0.82
73 INT93356 Negative_regulation of Gene_expression of Trp53 28 0.53 20.61 0.8
74 INT267095 Regulation of Gene_expression of Smad2 3 0.44 1.77 0.8
75 INT132127 Positive_regulation of Rps6 1 0.49 0.32 0.79
76 INT45293 Transcription of Srf 2 0.47 0.79 0.76
77 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75
78 INT48909 Localization of DLD 9 0.63 3.37 0.75
79 INT137007 Gene_expression of SMAD2 6 0.75 2.53 0.75
80 INT168245 Positive_regulation of Transcription of Tp53 2 0.70 2.63 0.75
81 INT162470 Negative_regulation of Protein_catabolism of TP53 1 0.32 1.24 0.74
82 INT265318 Negative_regulation of Gene_expression of Smad2 8 0.26 2.16 0.72
83 INT172960 Negative_regulation of Gene_expression of Smad4 7 0.39 5.88 0.71
84 INT45489 Gene_expression of SRF 5 0.77 3.29 0.71
85 INT269896 Positive_regulation of Gene_expression of Smad2 9 0.40 2.15 0.69
86 INT137009 Negative_regulation of Gene_expression of SMAD2 4 0.42 1.76 0.66
87 INT268377 Phosphorylation of SMAD2 7 0.80 0.85 0.65
88 INT302664 Positive_regulation of SMAD2 2 0.49 0.85 0.64
89 INT98239 Negative_regulation of Htt 13 0.43 7.84 0.6
90 INT93358 Negative_regulation of Positive_regulation of Trp53 9 0.41 3.95 0.6
91 INT53950 Phosphorylation of Tp53 8 0.61 9.4 0.6
92 INT45292 Negative_regulation of Transcription of Srf 1 0.06 0.65 0.59
93 INT287206 Regulation of Gene_expression of Htt 6 0.50 3.27 0.57
94 INT215340 Localization of Htt 10 0.61 5.12 0.55
95 INT103781 Negative_regulation of Smad4 9 0.42 4.42 0.54
96 INT287204 Protein_catabolism of Htt 6 0.99 2.8 0.53
97 INT55594 Negative_regulation of Positive_regulation of DLD 1 0.02 0.62 0.53
98 INT158889 Gene_expression of Smad2 5 0.65 1.25 0.51
99 INT119230 Negative_regulation of Htt 5 0.42 2.99 0.5
100 INT286035 Negative_regulation of Gene_expression of Tp53 5 0.32 6.2 0.49
101 INT266535 Phosphorylation of JUP 3 0.79 0.63 0.49
102 INT242168 Transcription of JUP 4 0.67 1.17 0.46
103 INT243418 Binding of Htt 14 0.30 5.94 0.44
104 INT165597 Positive_regulation of Htt 8 0.60 4.27 0.44
105 INT166382 Positive_regulation of Positive_regulation of Gnb2l1 1 0.50 0.2 0.44
106 INT132128 Positive_regulation of Phosphorylation of Rps6 1 0.49 0.16 0.4
107 INT237457 Positive_regulation of Gene_expression of MESP1 1 0.02 0.45 0.4
108 INT139976 Regulation of Tp53 7 0.44 6.49 0.39
109 INT132126 Phosphorylation of Rps6 1 0.80 0.16 0.39
110 INT132864 Binding of Htt 15 0.46 2.34 0.38
111 INT120899 Positive_regulation of Gene_expression of Tgfbr2 1 0.29 0.46 0.38
112 INT218691 Phosphorylation of Smad3 1 0.28 3 0.38
113 INT145220 Negative_regulation of Binding of Tp53 1 0.20 0.75 0.36
114 INT157804 Phosphorylation of Smad3 18 0.77 8.15 0.35
115 INT38203 Negative_regulation of Txnrd1 4 0.39 0.27 0.35
116 INT287207 Regulation of Protein_catabolism of Htt 3 0.45 1.73 0.35
117 INT242169 Positive_regulation of Protein_catabolism of JUP 1 0.49 0.23 0.34
118 INT185886 Gene_expression of JUP 20 0.75 15.41 0.32
119 INT181918 Positive_regulation of SMAD3 6 0.35 2.62 0.31
120 INT18821 Positive_regulation of Gene_expression of Srf 2 0.35 0.63 0.31
121 INT92100 Binding of Smad4 5 0.31 2.23 0.3
122 INT129908 Positive_regulation of Smad2 5 0.45 2.13 0.3
123 INT140795 Positive_regulation of Gene_expression of Smad3 3 0.48 3.16 0.3
124 INT137008 Positive_regulation of Gene_expression of SMAD2 2 0.49 0.51 0.3
125 INT93355 Negative_regulation of Negative_regulation of Trp53 2 0.41 0.92 0.3
126 INT179089 Protein_catabolism of Trp53 8 0.90 6.52 0.29
127 INT224877 Positive_regulation of Gene_expression of Smad2 1 0.12 0.16 0.29
128 INT254877 Positive_regulation of Gene_expression of Htt 15 0.64 6.29 0.28
129 INT172978 Negative_regulation of SMAD2 4 0.42 0.89 0.27
130 INT7610 Localization of Srf 3 0.67 0.98 0.27
131 INT221860 Negative_regulation of Jup 9 0.15 6.82 0.26
132 INT166960 Positive_regulation of Negative_regulation of TP53 2 0.25 1.65 0.26
133 INT262797 Regulation of Gene_expression of Smad3 2 0.34 2.27 0.25
134 INT314729 Regulation of Localization of TP53 1 0.30 2.5 0.25
135 INT179088 Positive_regulation of Regulation of Trp53 3 0.38 3.23 0.23
136 INT156886 Positive_regulation of Localization of TP53 1 0.48 0.87 0.23
137 INT129907 Regulation of Smad2 1 0.40 0.87 0.23
138 INT287205 Regulation of Htt 5 0.45 3.56 0.22
139 INT265311 Localization of Smad2 5 0.50 1.57 0.21
140 INT265334 Regulation of Phosphorylation of Smad2 2 0.17 0.96 0.2
141 INT234903 Gene_expression of Jup 1 0.23 7.1 0.2
142 INT310483 Positive_regulation of Eomes 2 0.38 0.85 0.19
143 INT310478 Positive_regulation of Transcription of Eomes 1 0.23 0.42 0.19
144 INT310466 Positive_regulation of Positive_regulation of Eomes 1 0.23 0.42 0.19
145 INT170390 Transcription of Eomes 2 0.31 0.51 0.18
146 INT128120 Transcription of DLD 1 0.67 0 0.18
147 INT157797 Negative_regulation of Phosphorylation of Smad3 3 0.40 0.95 0.17
148 INT268365 Binding of SMAD2 2 0.47 0.56 0.17
149 INT179828 Regulation of Positive_regulation of Rps6 1 0.04 0.07 0.17
150 INT300284 Regulation of Phosphorylation of Tp53 1 0.16 1.51 0.17
151 INT337078 Negative_regulation of Localization of Trp53 1 0.20 1.3 0.17
152 INT43708 Negative_regulation of Binding of DLD 1 0.35 0.17 0.17
153 INT179805 Positive_regulation of Rps6 1 0.10 0.07 0.16
154 INT179086 Positive_regulation of Negative_regulation of Trp53 5 0.50 4.78 0.15
155 INT125081 Positive_regulation of Binding of TP53 2 0.46 1.2 0.15
156 INT207805 Negative_regulation of Phosphorylation of Trp53 2 0.18 0.98 0.15
157 INT310481 Regulation of Eomes 1 0.28 0.1 0.15
158 INT89766 Binding of SRF 1 0.17 0.89 0.15
159 INT139977 Regulation of Smad4 1 0.16 1.41 0.15
160 INT89767 Positive_regulation of Binding of SRF 1 0.23 0.89 0.15
161 INT286749 Regulation of Localization of Trp53 1 0.06 1.39 0.15
162 INT135490 Localization of Smad2 1 0.51 0.08 0.14
163 INT205083 Positive_regulation of JUP 6 0.49 5.51 0.13
164 INT158903 Gene_expression of Smad3 2 0.56 0.54 0.13
165 INT158890 Negative_regulation of Gene_expression of Smad3 1 0.42 0.13 0.13
166 INT158893 Negative_regulation of Gene_expression of Smad2 1 0.30 0.13 0.13
167 INT168244 Regulation of Transcription of Tp53 1 0.33 0.57 0.13
168 INT129616 Negative_regulation of Phosphorylation of Smad2 4 0.38 0.78 0.12
169 INT83129 Protein_catabolism of DLD 1 0.02 0 0.12
170 INT311892 Regulation of Positive_regulation of Smad2 1 0.23 0.24 0.12
171 INT261711 Binding of GSC 1 0.32 0 0.11
172 INT156816 Regulation of Txnrd1 1 0.22 0 0.1
173 INT297456 Protein_catabolism of Tp53 1 0.11 0.72 0.1
174 INT111139 Localization of Tp53 4 0.45 2.4 0.09
175 INT242173 Positive_regulation of Gene_expression of JUP 2 0.49 2.37 0.09
176 INT137756 Regulation of Negative_regulation of DLD 1 0.02 0.09 0.09
177 INT325505 Transcription of Smad2 1 0.67 0.16 0.09
178 INT325510 Transcription of Smad4 1 0.67 0.16 0.09
179 INT309877 Localization of JUP 2 0.73 1.38 0.08
180 INT339206 Negative_regulation of Localization of JUP 1 0.41 1.1 0.08
181 INT234894 Negative_regulation of Protein_catabolism of Jup 1 0.17 2.87 0.08
182 INT287203 Negative_regulation of Gene_expression of Htt 7 0.37 5.08 0.07
183 INT352605 Regulation of Negative_regulation of Trp53 1 0.45 0.72 0.07
184 INT22789 Binding of Srf 1 0.37 0.07 0.07
185 INT22790 Positive_regulation of Binding of Srf 1 0.50 0.07 0.07
186 INT234866 Regulation of Jup 2 0.08 0.58 0.06
187 INT254790 Localization of Smad4 2 0.37 0.54 0.06
188 INT265317 Negative_regulation of Gene_expression of Smad3 2 0.41 0.9 0.06
189 INT190544 Transcription of Srf 1 0.19 0.43 0.06
190 INT261890 Positive_regulation of Gene_expression of Htt 1 0.43 0.85 0.06
191 INT234899 Positive_regulation of Protein_catabolism of Jup 1 0.21 0.88 0.06
192 INT190570 Localization of Srf 1 0.20 0.49 0.06
193 INT329585 Regulation of Negative_regulation of Jup 1 0.01 0.23 0.06
194 INT244341 Regulation of Binding of DLD 1 0.30 0.19 0.06
195 INT234931 Protein_catabolism of Jup 1 0.29 2.23 0.06
196 INT234915 Positive_regulation of Gene_expression of Jup 1 0.15 2.7 0.06
197 INT171421 Regulation of Positive_regulation of TP53 1 0.48 0.45 0.05
198 INT355863 Binding of EXT1 1 0.20 6.43 0.05
199 INT317175 Positive_regulation of Localization of Htt 1 0.48 0 0.05
200 INT306521 Transcription of Htt 1 0.69 4.13 0.05
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