GO:0007598

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Name blood coagulation, extrinsic pathway
Categary Process
Go Slim No
Go Link GO:0007598
Unique Molecular Interactions 46
Total Molecular Interactions 57
Total Single Events 617
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for blood coagulation, extrinsic pathway. They are ordered first by their pain relevance and then by number of times they were reported for blood coagulation, extrinsic pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT126781 Binding of F10 and Serpinc1 1 0.00 1.51 0.69
2 INT190702 CD40 Positive_regulation of Gene_expression of F3 1 0.00 1.4 0.55
3 INT84521 Binding of F7 and TF 1 0.06 0.09 0.37
4 INT174266 TNF Regulation of Gene_expression of F3 1 0.00 3.2 0.33
5 INT174265 IL18 Regulation of Gene_expression of F3 1 0.00 3.21 0.33
6 INT277011 CRP Positive_regulation of Gene_expression of F3 1 0.06 1.03 0.32
7 INT247081 Binding of F5 and F7 1 0.00 0.87 0.28
8 INT191503 CD40LG Regulation of Gene_expression of F3 1 0.01 0.99 0.27
9 INT282647 IL6 Positive_regulation of Gene_expression of F3 1 0.00 1.89 0.27
10 INT282648 IL8 Positive_regulation of Gene_expression of F3 1 0.00 1.89 0.27
11 INT220681 Binding of F10 and tf 1 0.03 1.47 0.26
12 INT308120 Binding of F2 and F10 2 0.07 1.25 0.25
13 INT179166 TFPI Positive_regulation of Gene_expression of IL6 1 0.03 0.18 0.25
14 INT84522 IRF6 Positive_regulation of Gene_expression of F3 1 0.08 0.1 0.21
15 INT220682 tf Positive_regulation of Positive_regulation of F10 1 0.04 0.67 0.19
16 INT247084 Binding of F7 and H1F0 1 0.00 0.38 0.17
17 INT281319 Binding of F7 and tf 1 0.24 1 0.16
18 INT111802 Binding of CD40LG and TFPI 1 0.14 0.62 0.16
19 INT191001 F3 Positive_regulation of F2 1 0.00 0.62 0.14
20 INT223040 AR Positive_regulation of Negative_regulation of TFPI 1 0.03 0 0.13
21 INT276497 F3 Positive_regulation of F7 1 0.02 1.64 0.1
22 INT8675 Positive_regulation of Binding of F2 and F3 2 0.17 0.43 0.09
23 INT8671 Binding of F2 and F3 2 0.13 0.42 0.09
24 INT8674 Positive_regulation of Binding of F3 and ANGPTL5 1 0.06 0.48 0.09
25 INT298502 F10 Positive_regulation of F2 1 0.00 0.12 0.09
26 INT8678 Binding of F3 and ANGPTL5 1 0.04 0.48 0.09
27 INT223039 Gene_expression of TFPI Positive_regulation of Gene_expression of ADRBK1 1 0.11 0 0.07
28 INT223043 Gene_expression of TFPI Positive_regulation of Gene_expression of ADRBK2 1 0.12 0 0.07
29 INT25491 TFPI Regulation of Localization of ENG 1 0.27 0.31 0.06
30 INT25490 Binding of ENG and TFPI 1 0.27 0.4 0.06
31 INT28705 F7 Negative_regulation of TFPI 1 0.02 0.66 0.06
32 INT349665 Positive_regulation of Binding of AR and TFPI 1 0.02 0 0.05
33 INT349667 Binding of AR and TFPI 1 0.02 0 0.05
34 INT349663 Binding of TFPI and PYCARD 1 0.04 0 0.04
35 INT323674 Binding of TFPI and THBD 1 0.02 2.45 0.04
36 INT223041 Binding of ADRBK1 and TFPI 1 0.08 0 0.03
37 INT223038 Binding of ADRBK2 and TFPI 1 0.09 0 0.03
38 INT255012 TF Positive_regulation of F10 1 0.06 0.06 0
39 INT355636 OLR1 Positive_regulation of Positive_regulation of F3 1 0.01 0.57 0
40 INT276493 TFPI Regulation of TF 1 0.12 0.17 0
41 INT354487 Binding of F9 and PLEK 1 0.52 0.14 0
42 INT130413 TNFSF14 Positive_regulation of F3 1 0.11 0 0
43 INT355640 OLR1 Positive_regulation of Gene_expression of F3 1 0.01 0.57 0
44 INT255019 Myo7a Positive_regulation of F10 1 0.00 0.06 0
45 INT308121 Binding of CA2 and F10 1 0.04 0.23 0
46 INT230416 F3 Regulation of MSLN 1 0.06 0.09 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for blood coagulation, extrinsic pathway. They are ordered first by their pain relevance and then by number of times they were reported in blood coagulation, extrinsic pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT25493 Gene_expression of TFPI 74 0.76 39.44 14.78
2 INT17035 Positive_regulation of TFPI 55 0.61 34.88 14.18
3 INT59870 Gene_expression of F3 51 0.65 51.83 14.01
4 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21
5 INT12039 Localization of TFPI 22 0.68 9.88 5.35
6 INT28703 Negative_regulation of TFPI 29 0.38 19.81 4.93
7 INT2947 Regulation of TFPI 10 0.44 5.81 4.86
8 INT35609 Negative_regulation of F10 37 0.57 17.15 4.41
9 INT54102 Positive_regulation of Gene_expression of TFPI 14 0.49 6.67 3.54
10 INT84527 Positive_regulation of Gene_expression of F3 16 0.49 15.83 2.85
11 INT39560 Positive_regulation of F10 25 0.67 10.67 2.5
12 INT38871 Binding of TFPI 12 0.32 5.9 2.36
13 INT46088 Localization of F3 15 0.37 13.7 2.23
14 INT9840 Positive_regulation of F7 17 0.57 17.83 2.08
15 INT96132 Gene_expression of F10 10 0.58 6.99 1.24
16 INT25492 Positive_regulation of Positive_regulation of TFPI 4 0.50 1.44 1.16
17 INT335454 Negative_regulation of Localization of TFPI 1 0.25 3.24 0.93
18 INT82845 Binding of F10 25 0.37 7.07 0.81
19 INT46087 Regulation of F3 4 0.45 3.49 0.68
20 INT107779 Negative_regulation of F7 3 0.30 2.99 0.66
21 INT3201 Positive_regulation of F9 11 0.49 5.12 0.56
22 INT174271 Binding of F3 6 0.15 6.85 0.53
23 INT335451 Positive_regulation of Localization of TFPI 1 0.29 1.65 0.48
24 INT115612 Regulation of Gene_expression of TFPI 2 0.17 0.27 0.44
25 INT223057 Negative_regulation of Gene_expression of TFPI 1 0.16 0.25 0.43
26 INT200523 Regulation of F7 2 0.01 1.82 0.38
27 INT247095 Binding of F7 2 0.03 1.91 0.37
28 INT54100 Phosphorylation of TFPI 1 0.00 1.09 0.36
29 INT174272 Negative_regulation of Gene_expression of F3 5 0.14 4.06 0.31
30 INT252656 Positive_regulation of Binding of F3 1 0.07 1.89 0.29
31 INT255014 Negative_regulation of Binding of F10 7 0.34 1.81 0.28
32 INT90653 Negative_regulation of Negative_regulation of F10 1 0.04 0.67 0.25
33 INT198659 Protein_catabolism of F10 1 0.01 0.51 0.22
34 INT221999 Gene_expression of F7 2 0.65 2.1 0.2
35 INT138506 Negative_regulation of F3 2 0.04 1.23 0.2
36 INT287790 Positive_regulation of Gene_expression of F7 1 0.49 1.55 0.2
37 INT35073 Transcription of F3 1 0.03 0.34 0.17
38 INT223049 Regulation of Binding of TFPI 1 0.17 0 0.16
39 INT242196 Positive_regulation of Localization of F3 3 0.09 1.71 0.15
40 INT47983 Negative_regulation of Positive_regulation of TFPI 2 0.22 0.32 0.15
41 INT223053 Regulation of Localization of TFPI 1 0.17 0 0.15
42 INT313645 Regulation of Positive_regulation of F10 1 0.19 0.49 0.14
43 INT313646 Regulation of F10 1 0.19 0.49 0.14
44 INT174262 Negative_regulation of Positive_regulation of F10 2 0.41 0.83 0.08
45 INT129458 Regulation of Localization of F7 1 0.19 0.33 0.08
46 INT129459 Localization of F7 1 0.31 0.33 0.08
47 INT327443 Regulation of Gene_expression of F3 1 0.03 0.67 0.08
48 INT96131 Positive_regulation of Gene_expression of F10 1 0.14 0.72 0.07
49 INT9843 Negative_regulation of Positive_regulation of F7 1 0.48 0.83 0.06
50 INT242195 Positive_regulation of Negative_regulation of F10 1 0.01 0.34 0.03
51 INT223050 Negative_regulation of Binding of TFPI 1 0.16 0 0.03
52 INT313644 Negative_regulation of Gene_expression of F10 1 0.34 1.02 0.03
53 INT213647 Gene_expression of F9 10 0.65 6.48 0
54 INT81028 Negative_regulation of F9 3 0.49 2.14 0
55 INT240052 Negative_regulation of Gene_expression of F9 2 0.04 1.32 0
56 INT10137 Negative_regulation of Positive_regulation of F9 1 0.00 0 0
57 INT308127 Positive_regulation of Localization of F10 1 0.35 0.11 0
58 INT344281 Positive_regulation of Negative_regulation of TFPI 1 0.38 1.47 0
59 INT222000 Regulation of Gene_expression of F7 1 0.08 0.76 0
60 INT325340 Positive_regulation of Binding of F10 1 0.09 0.37 0
61 INT222002 Negative_regulation of Gene_expression of F7 1 0.13 0.57 0
62 INT265506 Binding of F9 1 0.03 0.38 0
63 INT308128 Localization of F10 1 0.52 0.88 0
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