GO:0008013

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Name beta-catenin binding
Categary Function
Go Slim No
Go Link GO:0008013
Unique Molecular Interactions 1156
Total Molecular Interactions 1587
Total Single Events 13806
Pain Genes Associated 69

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for beta-catenin binding. They are ordered first by their pain relevance and then by number of times they were reported for beta-catenin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT296484 Binding of Gria2 and GRIP1 1 0.04 4.52 4.59
2 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 0.51 1.79 3.22
3 INT251147 Binding of Grin2b and Dlg2 1 0.33 2.75 2.43
4 INT107578 Kitl Negative_regulation of Grin2b 1 0.12 2.05 2.36
5 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
6 INT168608 Binding of Grin2b and Mmp9 1 0.22 0.41 1.57
7 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
8 INT246519 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Ltp 1 0.25 0.08 1.42
9 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
10 INT158079 Binding of Esr1 and Gper 1 0.31 0.97 1.35
11 INT222182 Binding of ESR1 and HLA-DRB2 1 0.00 3.1 1.35
12 INT150890 Binding of Esr1 and Esr2 2 0.52 2.06 1.31
13 INT154518 Binding of Ephb6 and Grin2b 1 0.21 0.24 1.28
14 INT84886 APC Regulation of PPARD 1 0.51 1.57 1.26
15 INT112105 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2b 2 0.40 0.89 1.2
16 INT105918 Binding of FUT1 and SLC9A3R2 1 0.00 0.14 1.2
17 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19
18 INT122267 Prkcg Positive_regulation of Grin2b 1 0.26 0.61 1.14
19 INT122268 Binding of Grin2b and Grm5 1 0.40 0.52 1.1
20 INT256294 Binding of Grin2b and Ephb1 1 0.28 1.11 1.08
21 INT291966 Pag1 Positive_regulation of Gene_expression of Grin2b 1 0.19 1.91 1.06
22 INT256293 Binding of Grin2b and Insrr 1 0.01 1.06 1.05
23 INT291964 Phex Regulation of Gene_expression of Grin2b 1 0.08 1.39 1.04
24 INT346835 Gene_expression of Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.27 1.07 1.03
25 INT353690 Binding of Grin2b and Ca2 1 0.14 1.17 1.01
26 INT344389 Ephb2 Positive_regulation of Phosphorylation of Grin2b 1 0.16 1.46 0.98
27 INT238091 Binding of GRIP1 and Mmp24 1 0.00 0 0.98
28 INT278292 Binding of CRP and ESR1 6 0.09 10.92 0.96
29 INT344381 Olfr360 Negative_regulation of Gene_expression of Grin2b 1 0.01 1.17 0.93
30 INT344390 Olfr360 Negative_regulation of Phosphorylation of Grin2b 1 0.01 1.17 0.93
31 INT344388 Efnb1 Positive_regulation of Phosphorylation of Grin2b 1 0.40 1.45 0.92
32 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
33 INT251152 Dlg2 Positive_regulation of Localization of Grin2b 1 0.43 0.6 0.92
34 INT291962 Pag1 Negative_regulation of Gene_expression of Grin2b 1 0.17 1.56 0.92
35 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
36 INT108438 Grin2b Regulation of Pdyn 1 0.16 0.25 0.9
37 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85
38 INT278690 LEF1 Negative_regulation of Gene_expression of IK 1 0.00 0.66 0.83
39 INT212290 Binding of Grin2a and Grin2b 2 0.20 1.36 0.82
40 INT278697 LEF1 Negative_regulation of STAT6 1 0.00 0.44 0.78
41 INT108812 Esr1 Positive_regulation of Positive_regulation of Oprm1 1 0.42 0.38 0.78
42 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
43 INT332538 Binding of AD5 and Cxadr 1 0.08 0.98 0.76
44 INT137699 AR Regulation of PDYN 1 0.46 0.93 0.75
45 INT195778 Binding of APC and PROCR 7 0.19 3.78 0.73
46 INT72229 Binding of NFKBIL1 and BTRC 1 0.00 0 0.73
47 INT314203 Nos2 Positive_regulation of Gli3 1 0.19 1.27 0.73
48 INT296285 Binding of Car1 and Grin2b 1 0.14 0.32 0.72
49 INT186160 Negative_regulation of Grin2b Negative_regulation of Grin1 1 0.37 0.5 0.72
50 INT296282 Grin2b Regulation of Negative_regulation of Kcnip3 1 0.30 0.3 0.72
51 INT296295 Binding of Grin1 and Grin2b 1 0.16 0.31 0.71
52 INT296298 Grin2b Regulation of Negative_regulation of Hmmr 1 0.03 0.29 0.71
53 INT12238 CCK Positive_regulation of CDH2 1 0.02 0 0.7
54 INT335596 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Car2 1 0.12 0.19 0.69
55 INT249485 Trib3 Negative_regulation of Phosphorylation of Grin2b 1 0.02 0.64 0.68
56 INT68561 Binding of Gli3 and Ust 1 0.01 0.68 0.68
57 INT74728 Binding of Slc6a4 and Ptprj 1 0.01 0.48 0.68
58 INT250084 Negative_regulation of Grin2b Negative_regulation of Positive_regulation of Ltp 1 0.18 0.07 0.66
59 INT74729 Binding of Mpz and Ptprj 1 0.06 0.15 0.66
60 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66
61 INT250078 Negative_regulation of Grin2b Negative_regulation of Ltp 1 0.18 0.07 0.66
62 INT224823 CTBS Regulation of SALL1 1 0.14 0.53 0.66
63 INT38057 Binding of Crp and Esr1 2 0.04 1.21 0.65
64 INT302441 Binding of GRIN1 and Grin2b 1 0.10 1.27 0.63
65 INT186159 Grin2d Negative_regulation of Grin2b 1 0.21 0.82 0.62
66 INT249484 Trib3 Positive_regulation of Phosphorylation of Grin2b 1 0.01 0.57 0.61
67 INT309158 Binding of Esr1 and Dlat 1 0.04 1.39 0.61
68 INT296486 Binding of Pick1 and GRIP1 1 0.03 0.32 0.59
69 INT261372 Gsk3b Regulation of Gene_expression of Ifi205 1 0.00 0.24 0.58
70 INT177269 Binding of CXADR and NR1H4 1 0.04 0 0.58
71 INT341594 Binding of ESR1 and HLA-B 1 0.01 0.72 0.57
72 INT141362 EP300 Negative_regulation of Transcription of IL2 1 0.17 0 0.56
73 INT296483 Prkca Positive_regulation of Localization of GRIP1 1 0.02 0.31 0.55
74 INT251141 Binding of Dlg4 and Grin2b 1 0.14 0.32 0.55
75 INT167651 Binding of Oprd1 and Ep300 1 0.02 0.09 0.55
76 INT251143 Binding of Grin2b and Dlg3 1 0.22 0.32 0.55
77 INT343913 Binding of FOS and Smad3 1 0.19 0.92 0.54
78 INT249497 Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.02 0.51 0.54
79 INT296485 Negative_regulation of Binding of Gria2 and GRIP1 1 0.05 0.3 0.54
80 INT249479 Binding of Ephb1 and Grin2b 1 0.29 0.37 0.54
81 INT208121 Binding of Grin2a and Grin2b 3 0.35 0.06 0.51
82 INT167652 Binding of Ep300 and Ngf 1 0.09 0.06 0.51
83 INT167655 Binding of Polr2f and Ep300 1 0.01 0.06 0.51
84 INT150833 Esr1 Positive_regulation of Localization of Prkce 1 0.08 0.29 0.51
85 INT291556 Binding of ESR1 and Sec22b 2 0.00 0.86 0.5
86 INT122107 Plbd2 Negative_regulation of Cdh2 1 0.03 0.42 0.5
87 INT154014 Binding of Esr1 and Gabrg1 1 0.07 0.07 0.5
88 INT250080 Grin2b Positive_regulation of Ltp 1 0.22 0.19 0.49
89 INT208119 Grin2b Positive_regulation of Positive_regulation of Ltp 1 0.16 0.21 0.49
90 INT72230 Binding of BTRC and EMID1 1 0.00 0 0.49
91 INT72227 Binding of BTRC and AP1M2 1 0.00 0 0.49
92 INT182150 Binding of APC and DCPS 1 0.02 1.14 0.48
93 INT114297 Apc Negative_regulation of Gene_expression of Fcer2a 1 0.03 0.96 0.48
94 INT134046 Jak2 Regulation of Gsk3b 1 0.22 0.13 0.47
95 INT185917 Binding of AR and MAPK1 1 0.07 0.5 0.47
96 INT147179 Esr1 Regulation of Gene_expression of Penk 1 0.01 0.68 0.46
97 INT249486 Positive_regulation of Ephb1 Positive_regulation of Phosphorylation of Grin2b 1 0.33 0.4 0.46
98 INT195552 Binding of Rela and Ep300 1 0.03 0.2 0.45
99 INT195554 Binding of Nfkb1 and Ep300 1 0.08 0.2 0.45
100 INT252425 Positive_regulation of AR Positive_regulation of Gene_expression of CXCL10 1 0.00 0.9 0.44
101 INT332539 Regulation of Binding of AD5 and Cxadr 1 0.09 0.65 0.44
102 INT297316 Negative_regulation of Rock2 Positive_regulation of Cdh1 1 0.01 1.92 0.43
103 INT130975 Binding of ASIC3 and Slc9a3r1 1 0.06 0.26 0.43
104 INT323840 Binding of Esr1 and Il1 1 0.04 0.9 0.42
105 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
106 INT261370 Nsdhl Regulation of Esr1 1 0.01 0.75 0.41
107 INT105733 Grin2b Negative_regulation of Gene_expression of Grin2a 1 0.22 0.09 0.41
108 INT296296 Binding of Grin2b and Kcnip3 1 0.24 0 0.4
109 INT279620 Negative_regulation of Binding of Grin2a and Grin2b 1 0.18 0.99 0.4
110 INT139047 Negative_regulation of AR Negative_regulation of Positive_regulation of CPOX 1 0.07 0.76 0.4
111 INT117361 Binding of Esr1 and sea 1 0.02 1.38 0.38
112 INT199974 ESR1 Negative_regulation of Gene_expression of ITGB3BP 1 0.05 0.47 0.38
113 INT291616 Cby1 Positive_regulation of Gene_expression of Smad7 1 0.00 0.79 0.38
114 INT197591 Esr1 Regulation of Pgr 1 0.04 0 0.38
115 INT288545 Gsk3b Negative_regulation of gr 1 0.25 0.38 0.38
116 INT117359 Binding of Esr1 and Wbc1 1 0.00 1.38 0.37
117 INT84887 APC Negative_regulation of Gene_expression of PPARD 1 0.36 0.55 0.37
118 INT150196 Grm5 Regulation of Grin2b 1 0.45 0 0.36
119 INT130974 Slc9a3r1 Positive_regulation of ASIC3 1 0.08 0.29 0.36
120 INT152453 Gsk3b Regulation of Nfkb1 1 0.02 1.68 0.36
121 INT249492 Trib3 Regulation of Phosphorylation of Grin2b 1 0.01 0.23 0.35
122 INT252453 Binding of AR and Adora2b 1 0.05 0 0.35
123 INT291555 Binding of ESR1 and Dlat 1 0.01 0.6 0.35
124 INT66369 Pomc Regulation of Positive_regulation of Gsk3b 1 0.07 0 0.35
125 INT236006 HTR1A Regulation of Grin2b 1 0.00 0 0.33
126 INT291554 Binding of ESR1 and St8sia2 1 0.01 0.49 0.33
127 INT321366 Gsk3b Regulation of Gene_expression of CYP8B1 1 0.01 0.21 0.33
128 INT75641 AR Positive_regulation of Positive_regulation of EIF2B3 1 0.02 0 0.33
129 INT349664 PYCARD Negative_regulation of Localization of AR 1 0.05 0 0.32
130 INT296482 Binding of GRIP1 and Myo18a 1 0.00 0.35 0.32
131 INT195665 APC Negative_regulation of F8 1 0.04 1.53 0.32
132 INT165580 Binding of Akt1 and Grin2b 1 0.02 0.2 0.32
133 INT349662 Binding of PYCARD and Negative_regulation of Localization of AR 1 0.05 0 0.32
134 INT242164 Wnt2 Positive_regulation of Localization of Apc 1 0.13 1.53 0.32
135 INT128756 Binding of Esr1 and Foxc1 1 0.01 0.43 0.32
136 INT198566 Ddit4l Regulation of Axin1 1 0.03 1 0.31
137 INT195664 APC Negative_regulation of F5 1 0.08 1.51 0.31
138 INT342810 Binding of Adarb1 and Gsk3b 1 0.00 0.36 0.3
139 INT63122 Binding of APC and Man2a2 1 0.01 0.15 0.3
140 INT309156 Esr1 Regulation of Gene_expression of Dlat 1 0.05 1.06 0.3
141 INT263749 Binding of Grin2b and Neto1 1 0.38 0 0.3
142 INT222301 Binding of ERBB2 and ESR1 5 0.36 5.07 0.29
143 INT158734 Esr1 Regulation of Esrrb 1 0.00 0.28 0.29
144 INT250079 Grin2b Regulation of Ltp 1 0.18 0.31 0.29
145 INT158733 Esr1 Regulation of Plxna3 1 0.03 0.27 0.29
146 INT309063 Binding of Trpc3 and Trpc4 1 0.11 0.23 0.28
147 INT289954 Binding of APC and CD28 1 0.03 0.38 0.28
148 INT309056 Binding of Trpc4 and Trpc6 1 0.15 0.23 0.28
149 INT185092 CRP Positive_regulation of ESR1 1 0.06 2.83 0.28
150 INT199978 ESR1 Regulation of ITGB3BP 1 0.03 0.39 0.28
151 INT325530 Positive_regulation of Gsk3b Negative_regulation of Gene_expression of Wnt2 1 0.03 0.63 0.28
152 INT71904 Binding of ESR1 and PGR 6 0.34 3.79 0.27
153 INT323152 Binding of DBT and ESR1 2 0.02 1.29 0.27
154 INT312894 Binding of Gsk3b and Positive_regulation of Gene_expression of Hdac6 1 0.08 1.3 0.27
155 INT350813 Binding of Apc and Crp 1 0.18 1.12 0.27
156 INT249493 Binding of Grin2b and Src 1 0.17 0.15 0.26
157 INT346195 AMELX Negative_regulation of ESR1 1 0.02 0.36 0.26
158 INT263587 Pdia3 Negative_regulation of Binding of Esr1 1 0.07 1.86 0.26
159 INT223042 AR Positive_regulation of ADCY1 1 0.01 0.41 0.25
160 INT297547 Pou3f3 Regulation of Psen1 1 0.00 0.41 0.25
161 INT186783 Binding of ESR1 and NRIP1 1 0.31 0.79 0.25
162 INT199970 CYP19A1 Positive_regulation of Gene_expression of ESR1 1 0.06 0.72 0.25
163 INT182346 Binding of Cd3e and Esr1 1 0.06 1.26 0.25
164 INT182349 Binding of Ms4a1 and Esr1 1 0.04 1.26 0.25
165 INT235976 Binding of APC and Trav6-3 2 0.01 2.62 0.24
166 INT235974 Negative_regulation of Binding of APC and Trav6-3 1 0.00 1.15 0.24
167 INT199971 IL6 Positive_regulation of ESR1 1 0.08 0.84 0.24
168 INT257776 Phosphorylation of AR Positive_regulation of Localization of TAB2 1 0.26 0.38 0.24
169 INT252427 IGKV2D-29 Regulation of Gene_expression of AR 1 0.02 0 0.24
170 INT256656 Binding of EP300 and HHIP 1 0.22 0 0.24
171 INT309160 Binding of Esr1 and Edc4 1 0.03 0.34 0.24
172 INT235972 Negative_regulation of Binding of APC and Bcr 1 0.01 1.15 0.24
173 INT235973 Binding of APC and Bcr 1 0.01 1.14 0.24
174 INT72231 Negative_regulation of Binding of NFKBIL1 and BTRC 1 0.00 0 0.24
175 INT139046 Negative_regulation of AR Negative_regulation of Phosphorylation of DYT10 1 0.33 0.34 0.23
176 INT139050 Negative_regulation of AR Negative_regulation of Phosphorylation of PRKCB 1 0.02 0.34 0.23
177 INT63203 INS Positive_regulation of ESR1 1 0.09 0.3 0.23
178 INT139045 Negative_regulation of AR Negative_regulation of CPOX 1 0.07 0.34 0.23
179 INT139048 Negative_regulation of AR Negative_regulation of Positive_regulation of TRAF3IP2 1 0.02 0.34 0.23
180 INT109408 Negative_regulation of APC Negative_regulation of Positive_regulation of RASGRP1 1 0.06 0.73 0.23
181 INT139049 Negative_regulation of AR Negative_regulation of Positive_regulation of DYT10 1 0.33 0.34 0.23
182 INT63198 POMC Positive_regulation of ESR1 1 0.14 0.3 0.23
183 INT250783 APC Negative_regulation of SERPINE1 1 0.06 0.86 0.23
184 INT317034 Binding of GRIP1 and Tmub1 1 0.02 0.11 0.23
185 INT250782 APC Negative_regulation of F2 1 0.00 0.86 0.23
186 INT283948 SALL1 Positive_regulation of Positive_regulation of Ptgfrn 1 0.00 0.21 0.22
187 INT316111 APC Negative_regulation of SAE1 1 0.04 1.21 0.22
188 INT270135 Binding of ESR1 and RALA 1 0.11 0.37 0.22
189 INT63192 PTH Positive_regulation of ESR1 1 0.20 0.29 0.22
190 INT195663 APC Negative_regulation of Gene_expression of IL6 1 0.16 1.18 0.22
191 INT273237 Cdk5 Positive_regulation of Protein_catabolism of Grin2b 1 0.45 1.31 0.22
192 INT208123 Hpcal1 Regulation of Grin2b 1 0.10 0 0.21
193 INT270433 PLAT Positive_regulation of Positive_regulation of Gsk3b 1 0.04 0.5 0.21
194 INT316110 Binding of APC and SAE1 1 0.03 1.16 0.2
195 INT178074 EDN1 Positive_regulation of Phosphorylation of PXN 1 0.05 0.82 0.2
196 INT250074 Grin2b Positive_regulation of Gene_expression of Hpcal4 1 0.04 0.3 0.2
197 INT308645 Binding of Esr1 and Itpr3 1 0.00 0 0.2
198 INT325529 Binding of Stat3 and Ep300 1 0.01 0.22 0.19
199 INT351086 Negative_regulation of ERBB2 Positive_regulation of Gene_expression of ESR1 1 0.10 0.75 0.19
200 INT351089 FOXO3 Positive_regulation of Gene_expression of ESR1 1 0.04 0.74 0.19

Single Events

The table below shows the top 100 pain related interactions that have been reported for beta-catenin binding. They are ordered first by their pain relevance and then by number of times they were reported in beta-catenin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48
2 INT92518 Gene_expression of Grin2b 131 0.78 65.52 80.91
3 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42
4 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34
5 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64
6 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81
7 INT94029 Positive_regulation of Grin2b 58 0.70 24.2 42.52
8 INT82054 Positive_regulation of Grin2b 56 0.70 17.45 37.14
9 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69
10 INT103998 Positive_regulation of Phosphorylation of Grin2b 33 0.69 19.08 36.08
11 INT130479 Phosphorylation of Grin2b 28 0.77 34.82 34.97
12 INT93451 Positive_regulation of Gene_expression of Grin2b 43 0.70 29.09 31.89
13 INT93033 Negative_regulation of Grin2b 48 0.58 20.94 28.54
14 INT37296 Binding of Esr1 117 0.43 62.51 27.33
15 INT5206 Gene_expression of AR 316 0.78 113.83 27.29
16 INT20462 Binding of ESR1 210 0.44 102.7 26.34
17 INT107577 Negative_regulation of Grin2b 32 0.59 12.35 24.88
18 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52
19 INT102281 Positive_regulation of Gene_expression of Grin2b 27 0.70 10.38 20.84
20 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66
21 INT4067 Negative_regulation of Esr1 97 0.50 43.45 17.52
22 INT17237 Regulation of Esr1 74 0.43 49.09 17.25
23 INT93037 Regulation of Grin2b 26 0.57 11.9 16.92
24 INT92514 Regulation of Grin2b 22 0.50 11.07 16.92
25 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
26 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51
27 INT92354 Localization of ESR1 77 0.75 33.04 15.51
28 INT73916 Gene_expression of Esr1 58 0.77 26.59 15.15
29 INT124372 Gene_expression of Gsk3b 164 0.75 95.64 14.35
30 INT2038 Localization of Esr1 104 0.79 40.12 13.27
31 INT103996 Negative_regulation of Phosphorylation of Grin2b 11 0.58 7.81 12.85
32 INT122117 Negative_regulation of Gene_expression of Grin2b 20 0.59 11.3 12.55
33 INT79545 Positive_regulation of Gene_expression of ESR1 82 0.64 39.42 12.18
34 INT36715 Gene_expression of Trpc4 50 0.68 4.18 11.13
35 INT130475 Positive_regulation of Phosphorylation of Grin2b 8 0.47 11.52 10.96
36 INT238920 Positive_regulation of SLC9A3R2 44 0.50 27.86 10.51
37 INT80006 Regulation of Gene_expression of Grin2b 8 0.57 3.75 9.62
38 INT95342 Gene_expression of GRIN2B 21 0.75 4.99 9.32
39 INT135372 Positive_regulation of Gsk3b 72 0.70 50.03 9.28
40 INT152668 Negative_regulation of EP300 13 0.38 7.78 9.03
41 INT35366 Binding of AR 87 0.47 30.52 8.9
42 INT57057 Gene_expression of APC 131 0.78 122.24 8.7
43 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
44 INT112104 Binding of Grin2b 21 0.44 6.78 8.16
45 INT15687 Regulation of ESR1 91 0.60 40.42 7.95
46 INT16631 Negative_regulation of APC 46 0.57 30.53 7.11
47 INT83952 Gene_expression of Cxadr 24 0.75 22.38 6.77
48 INT110987 Transcription of ESR1 45 0.71 24.16 6.72
49 INT50387 Negative_regulation of AR 67 0.45 26.31 6.61
50 INT22901 Negative_regulation of Gene_expression of Esr1 30 0.42 20.92 6.29
51 INT100658 Negative_regulation of Positive_regulation of Grin2b 7 0.41 1.39 6.17
52 INT3819 Positive_regulation of Apc 36 0.69 27.03 6.02
53 INT74593 Transcription of Grin2b 10 0.66 1.21 5.98
54 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
55 INT130472 Negative_regulation of Phosphorylation of Grin2b 4 0.40 4.4 5.78
56 INT20280 Positive_regulation of Esr1 32 0.69 18.37 5.69
57 INT105960 Gene_expression of Cdh1 41 0.76 22.28 5.56
58 INT43997 Positive_regulation of Gene_expression of Esr1 57 0.51 36.66 5.51
59 INT124370 Positive_regulation of Gene_expression of Gsk3b 47 0.67 24.56 5.4
60 INT127353 Regulation of Phosphorylation of Grin2b 5 0.45 1.6 5.29
61 INT130478 Localization of Grin2b 11 0.75 2.49 5.28
62 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22
63 INT92541 Localization of Grin2b 11 0.75 2.85 5.14
64 INT57064 Positive_regulation of APC 72 0.66 48.5 5.08
65 INT99091 Regulation of AR 70 0.45 31.68 5.05
66 INT68559 Negative_regulation of Gli3 5 0.37 4.56 4.93
67 INT16621 Negative_regulation of Esr1 20 0.54 8.2 4.84
68 INT135374 Binding of Gsk3b 46 0.48 24.36 4.75
69 INT5205 Localization of AR 43 0.80 12.87 4.63
70 INT84727 Negative_regulation of Gene_expression of AR 38 0.58 12.46 4.63
71 INT79505 Binding of Grin2b 9 0.36 1.43 4.61
72 INT133630 Negative_regulation of Gene_expression of ESR1 42 0.52 23.89 4.57
73 INT2213 Regulation of EP300 10 0.54 4.72 4.5
74 INT119203 Gene_expression of CXADR 64 0.74 11.37 4.41
75 INT66366 Positive_regulation of Gsk3b 15 0.68 6.56 4.27
76 INT170348 Regulation of Gene_expression of Grin2b 8 0.60 2.29 4.25
77 INT112100 Negative_regulation of Gene_expression of Grin2b 6 0.42 3.71 4.24
78 INT167284 Phosphorylation of Gsk3b 88 0.82 36.03 4.21
79 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
80 INT117205 Transcription of Esr1 23 0.65 9.4 4.14
81 INT41878 Positive_regulation of EP300 13 0.61 5.24 3.95
82 INT3817 Negative_regulation of Apc 29 0.58 22.12 3.91
83 INT116642 Negative_regulation of Gsk3b 13 0.57 7.16 3.83
84 INT63121 Binding of APC 29 0.41 23.02 3.8
85 INT163500 Transcription of Grin2b 3 0.67 3.63 3.8
86 INT218955 Protein_catabolism of ESR1 9 0.92 3.95 3.74
87 INT139646 Positive_regulation of Positive_regulation of Grin2b 4 0.42 3.89 3.74
88 INT120072 Gene_expression of Smad7 38 0.74 20.87 3.69
89 INT20461 Binding of Esr1 34 0.48 9.58 3.66
90 INT5204 Positive_regulation of Gene_expression of AR 60 0.67 23.54 3.53
91 INT135373 Regulation of Gsk3b 35 0.62 18.11 3.53
92 INT178631 Phosphorylation of ESR1 21 0.75 9.16 3.36
93 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26
94 INT73918 Transcription of Esr1 21 0.66 8.74 3.12
95 INT66367 Gene_expression of Gsk3b 16 0.45 9.75 3.07
96 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95
97 INT54749 Binding of BTRC 7 0.09 0.88 2.9
98 INT31541 Regulation of Esr1 15 0.54 4.12 2.82
99 INT169323 Positive_regulation of Gene_expression of Cxadr 4 0.67 4.09 2.77
100 INT238088 Binding of GRIP1 6 0.04 2.35 2.75
101 INT174727 Positive_regulation of Positive_regulation of ESR1 14 0.44 6.3 2.7
102 INT224826 Gene_expression of SALL1 1 0.55 1.94 2.57
103 INT185927 Positive_regulation of Positive_regulation of AR 12 0.34 6.35 2.5
104 INT101055 Regulation of GRIN2B 4 0.61 1.39 2.5
105 INT126581 Positive_regulation of Gli3 6 0.35 1.59 2.48
106 INT163544 Binding of Psen1 40 0.36 15.28 2.42
107 INT171511 Gene_expression of EP300 14 0.53 4.17 2.29
108 INT177328 Positive_regulation of CXADR 9 0.48 4.29 2.27
109 INT169705 Negative_regulation of Gene_expression of Cdh1 10 0.57 8.8 2.1
110 INT181507 Positive_regulation of Psen1 22 0.49 7.59 2.04
111 INT26123 Regulation of Ep300 6 0.23 1.22 2.03
112 INT126374 Gene_expression of Gli3 6 0.77 3.67 2.02
113 INT171514 Binding of EP300 13 0.32 4.32 2.01
114 INT246518 Regulation of Negative_regulation of Grin2b 1 0.38 0.07 1.99
115 INT26124 Negative_regulation of Ep300 5 0.37 1.25 1.94
116 INT193939 Binding of PSEN1 10 0.36 6.16 1.93
117 INT73913 Regulation of Gene_expression of Esr1 2 0.41 2.24 1.92
118 INT151942 Regulation of Negative_regulation of Grin2b 2 0.41 0.41 1.92
119 INT218959 Negative_regulation of Protein_catabolism of ESR1 3 0.37 0.97 1.9
120 INT204018 Localization of Gsk3b 27 0.71 13.67 1.87
121 INT14914 Regulation of Cdh5 5 0.52 4.59 1.85
122 INT85337 Negative_regulation of Slc9a3r2 5 0.34 2.32 1.8
123 INT74594 Regulation of Transcription of Grin2b 1 0.42 0.17 1.8
124 INT130440 Phosphorylation of GRIN2B 2 0.79 2.93 1.79
125 INT111070 Negative_regulation of Gene_expression of Psen1 17 0.42 9.47 1.77
126 INT247811 Regulation of Gene_expression of Cxadr 2 0.34 2.61 1.77
127 INT174924 Gene_expression of Smad7 6 0.41 3.59 1.76
128 INT105920 Binding of SLC9A3R2 5 0.36 1.99 1.75
129 INT174923 Positive_regulation of Gene_expression of Smad7 3 0.37 2.3 1.73
130 INT44637 Positive_regulation of Slc9a3r2 18 0.55 7.27 1.72
131 INT172622 Localization of EP300 8 0.65 2.56 1.72
132 INT111944 Phosphorylation of VCL 3 0.73 5.23 1.72
133 INT84722 Regulation of Gene_expression of AR 20 0.61 7.73 1.69
134 INT3818 Regulation of Apc 13 0.39 12.52 1.68
135 INT96971 Positive_regulation of Gene_expression of Esr1 6 0.46 2.27 1.67
136 INT10598 Gene_expression of Ar 10 0.64 3.44 1.61
137 INT15969 Negative_regulation of Ar 11 0.43 2.77 1.59
138 INT222089 Positive_regulation of Localization of Esr1 19 0.49 8.73 1.58
139 INT54750 Gene_expression of BTRC 4 0.14 0.99 1.55
140 INT278715 Gene_expression of LEF1 10 0.33 5.43 1.54
141 INT282434 Regulation of Gene_expression of Psen1 9 0.50 2.85 1.52
142 INT209307 Positive_regulation of Gene_expression of Trpc4 1 0.58 0.59 1.52
143 INT120227 Binding of Cxadr 17 0.45 8.02 1.51
144 INT177305 Positive_regulation of Gene_expression of CXADR 7 0.48 1.1 1.51
145 INT118311 Binding of Slc9a3r2 5 0.45 2.03 1.49
146 INT107379 Localization of GRIN2B 2 0.73 0.86 1.48
147 INT278727 Negative_regulation of Gene_expression of LEF1 3 0.11 1.59 1.47
148 INT140245 Binding of Gli3 3 0.36 2.65 1.46
149 INT296265 Regulation of Phosphorylation of Grin2b 2 0.44 1.06 1.4
150 INT220177 Binding of Apc 21 0.37 15.34 1.37
151 INT181509 Negative_regulation of Psen1 17 0.57 11.53 1.35
152 INT82932 Transcription of AR 14 0.67 5.75 1.34
153 INT100275 Gene_expression of TBL1XR1 19 0.25 6.99 1.33
154 INT68500 Regulation of Ar 6 0.27 4.16 1.32
155 INT161903 Regulation of Cxadr 4 0.43 1.9 1.32
156 INT152951 Negative_regulation of LEF1 5 0.41 3.22 1.31
157 INT110434 Positive_regulation of Gene_expression of Apc 20 0.50 11.37 1.3
158 INT8511 Localization of Esr1 6 0.80 3.27 1.26
159 INT120076 Positive_regulation of Gene_expression of Smad7 16 0.65 11.33 1.25
160 INT182474 Gene_expression of Cdh5 17 0.57 14.58 1.23
161 INT128752 Negative_regulation of Localization of Esr1 11 0.43 4.8 1.23
162 INT249527 Positive_regulation of Positive_regulation of Grin2b 2 0.37 1.12 1.22
163 INT213379 Phosphorylation of AR 6 0.63 2.03 1.21
164 INT134663 Gene_expression of SOX9 40 0.75 9.07 1.2
165 INT70821 Positive_regulation of Ep300 4 0.25 1.47 1.2
166 INT95347 Negative_regulation of GRIN2B 1 0.57 0 1.19
167 INT122103 Negative_regulation of Cdh1 5 0.49 2.05 1.18
168 INT824 Negative_regulation of Negative_regulation of ESR1 3 0.42 1.53 1.18
169 INT296479 Negative_regulation of Binding of GRIP1 1 0.05 1.55 1.18
170 INT167283 Negative_regulation of Phosphorylation of Gsk3b 12 0.59 7.94 1.16
171 INT102073 Regulation of Gene_expression of APC 5 0.45 6.09 1.15
172 INT134036 Regulation of Gsk3b 4 0.60 1.42 1.15
173 INT113865 Binding of CXADR 35 0.46 3.18 1.12
174 INT32545 Localization of Gsk3b 9 0.07 2.88 1.11
175 INT208536 Positive_regulation of Positive_regulation of Gsk3b 6 0.30 4.83 1.11
176 INT102074 Positive_regulation of Gene_expression of APC 20 0.50 13.66 1.1
177 INT184720 Negative_regulation of Smad3 8 0.55 5.23 1.1
178 INT169704 Regulation of Gene_expression of Cdh1 4 0.35 1.75 1.09
179 INT143091 Positive_regulation of Negative_regulation of Grin2b 2 0.44 0.9 1.09
180 INT291961 Negative_regulation of Regulation of Grin2b 1 0.30 1.65 1.09
181 INT286596 Positive_regulation of Positive_regulation of SLC9A3R2 2 0.50 3.37 1.07
182 INT81945 Negative_regulation of Binding of Esr1 3 0.32 0.55 1.06
183 INT286597 Localization of SLC9A3R2 3 0.54 6.71 1.05
184 INT105922 Gene_expression of SLC9A3R2 6 0.48 2.09 1.04
185 INT107874 Positive_regulation of Trpc4 3 0.58 0.09 1.02
186 INT122106 Localization of Cdh2 3 0.69 0.95 1
187 INT167650 Binding of Ep300 1 0.09 0.14 1
188 INT116646 Regulation of Negative_regulation of Gsk3b 2 0.44 0.39 0.99
189 INT71906 Regulation of Gene_expression of ESR1 22 0.41 11.01 0.98
190 INT154468 Negative_regulation of Transcription of ESR1 3 0.29 1.14 0.96
191 INT209679 Positive_regulation of Regulation of AR 3 0.37 1.88 0.96
192 INT173747 Regulation of Positive_regulation of Esr1 4 0.37 4.85 0.95
193 INT91771 Positive_regulation of Gene_expression of PSEN1 13 0.49 8.93 0.93
194 INT166715 Gene_expression of Sox9 16 0.65 6.39 0.92
195 INT236576 Positive_regulation of Binding of Esr1 3 0.41 2.39 0.92
196 INT154465 Negative_regulation of Transcription of Esr1 1 0.05 0 0.92
197 INT128755 Protein_catabolism of Esr1 10 0.57 4.61 0.9
198 INT261360 Binding of Gsk3b 5 0.36 2.85 0.9
199 INT101056 Positive_regulation of GRIN2B 1 0.23 0.32 0.9
200 INT242134 Localization of Apc 8 0.74 4.83 0.88
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