GO:0008094

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Name DNA-dependent ATPase activity
Categary Function
Go Slim No
Go Link GO:0008094
Unique Molecular Interactions 82
Total Molecular Interactions 116
Total Single Events 567
Pain Genes Associated 20

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for DNA-dependent ATPase activity. They are ordered first by their pain relevance and then by number of times they were reported for DNA-dependent ATPase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113715 Msh3 Positive_regulation of tf 1 0.11 0 2.47
2 INT104709 Msh3 Positive_regulation of Rbm39 1 0.01 0.07 1.76
3 INT145121 Msh3 Positive_regulation of Oprm1 1 0.06 0.15 0.72
4 INT145120 Msh3 Negative_regulation of Positive_regulation of Oprm1 1 0.05 0.15 0.72
5 INT145122 Oprm1 Negative_regulation of Msh3 1 0.06 0.15 0.63
6 INT122823 ERCC2 Regulation of Negative_regulation of OPRM1 1 0.23 0.17 0.63
7 INT148352 Binding of MC1R and XRCC3 1 0.36 0.34 0.62
8 INT142947 Binding of ERCC2 and OPRM1 1 0.05 0.3 0.32
9 INT121186 Binding of Msh3 and Em 1 0.02 0.1 0.3
10 INT182606 Binding of MSH2 and MSH3 1 0.12 1.4 0.21
11 INT29207 Msh2 Regulation of POMC 1 0.02 0.1 0.14
12 INT103557 Binding of ERCC2 and TP53 1 0.40 1 0.13
13 INT182607 Binding of MLH1 and MSH3 1 0.04 0.81 0.11
14 INT227836 Binding of ERCC6 and GPER 1 0.21 0.27 0.08
15 INT355542 Binding of XRCC3 and BCC1 1 0.00 1.19 0.07
16 INT190044 Binding of Msh2 and Msh6 2 0.32 0.77 0.05
17 INT333841 Binding of Rad51 and Mir17 1 0.02 0.52 0.05
18 INT190050 Binding of Msh2 and Pms2 2 0.32 0.49 0.04
19 INT190046 Binding of Msh3 and Pms2 2 0.25 0.5 0.04
20 INT290556 Binding of MLH1 and MSH2 3 0.34 2.74 0
21 INT189375 Rpa1 Regulation of ERCC6 1 0.04 0.05 0
22 INT227830 CSH1 Regulation of ERCC6 1 0.11 0 0
23 INT57107 Binding of Msh2 and Nts 1 0.22 0.22 0
24 INT212013 RAD51D Negative_regulation of ALPP 1 0.00 0.7 0
25 INT227837 Positive_regulation of Binding of CSH1 and ERCC6 1 0.20 0.15 0
26 INT286114 Binding of MSH6 and Mutyh 1 0.17 0 0
27 INT314742 Binding of RAD51 and Brca2 1 0.06 1.05 0
28 INT189373 Rpa1 Negative_regulation of ERCC6 1 0.03 0 0
29 INT314743 Binding of RAD51 and Brca1 1 0.06 1.06 0
30 INT227829 CFC1 Positive_regulation of Gene_expression of ERCC6 1 0.03 0 0
31 INT227838 Binding of ERCC6 and PGBD3 1 0.40 0.23 0
32 INT273949 Binding of Crem and Smarca4 1 0.01 0 0
33 INT212014 RAD51D Positive_regulation of Gene_expression of PRL 1 0.06 0.77 0
34 INT285772 ERCC1 Positive_regulation of Binding of RAD51 1 0.05 0 0
35 INT336780 Ighmbp2 Regulation of ERAP2 1 0.02 0.15 0
36 INT189330 PPA1 Positive_regulation of ERCC6 1 0.10 0 0
37 INT227832 Binding of CSH1 and ERCC6 1 0.15 0.15 0
38 INT227841 PGBD1 Positive_regulation of ERCC6 1 0.44 0.29 0
39 INT351982 Smarca4 Positive_regulation of Stk11 1 0.05 0.58 0
40 INT283062 ERCC8 Positive_regulation of CFH 1 0.02 1.88 0
41 INT212011 RAD51D Regulation of Localization of GNRH1 1 0.04 0.59 0
42 INT285771 ERCC1 Regulation of Binding of RAD51 1 0.05 0 0
43 INT189333 CSNK2A1 Positive_regulation of Phosphorylation of ERCC6 1 0.10 0 0
44 INT227833 Positive_regulation of CFC1 Positive_regulation of Gene_expression of ERCC6 1 0.03 0 0
45 INT190049 Binding of Mlh1 and Msh3 1 0.24 0.22 0
46 INT243233 Positive_regulation of Ighmbp2 Negative_regulation of Rs1 1 0.11 0.31 0
47 INT190048 Binding of Mlh1 and Msh2 1 0.31 0.22 0
48 INT212012 RAD51D Regulation of GNRH1 1 0.04 0.59 0
49 INT149429 ERCC2 Negative_regulation of Localization of IL8 1 0.05 0.38 0
50 INT276759 ABCB1 Regulation of TOP2A 1 0.04 0.61 0
51 INT227840 Binding of ERCC2 and ERCC6 1 0.11 0.66 0
52 INT212525 MSH6 Positive_regulation of Binding of C1qa 1 0.00 0.38 0
53 INT243235 Ighmbp2 Negative_regulation of Rs1 1 0.11 0.31 0
54 INT149431 ERCC2 Negative_regulation of Localization of Il6 1 0.14 0.2 0
55 INT189374 Binding of RAD51 and Rad54l 1 0.01 0 0
56 INT190062 Binding of MLH1 and Msh2 1 0.01 0.91 0
57 INT227831 Binding of ERCC2 and PGBD3 1 0.07 0.23 0
58 INT283061 Binding of ERCC8 and LDLR 1 0.00 0.44 0
59 INT300617 Binding of MSH6 and MLH1 1 0.28 0.53 0
60 INT305543 Binding of Top2a and Trp53 1 0.37 0.91 0
61 INT190047 Binding of Msh2 and Msh3 1 0.24 0.23 0
62 INT227843 Binding of ERCC6 and MLL 1 0.00 0.34 0
63 INT189331 PPA1 Negative_regulation of Phosphorylation of ERCC6 1 0.06 0 0
64 INT243232 Ighmbp2 Negative_regulation of Ptch1 1 0.02 0.22 0
65 INT149432 ERCC2 Regulation of Localization of Il6 1 0.15 1.06 0
66 INT149428 ERCC2 Regulation of Localization of IL8 1 0.05 0.53 0
67 INT212528 Binding of MSH6 and Apcs 1 0.00 0.68 0
68 INT230709 Binding of Cdk7 and Mnat1 1 0.29 0.09 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for DNA-dependent ATPase activity. They are ordered first by their pain relevance and then by number of times they were reported in DNA-dependent ATPase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT103899 Gene_expression of ERCC2 14 0.65 7.85 5.49
2 INT104705 Regulation of Msh3 4 0.28 0.1 3.51
3 INT104708 Gene_expression of Msh3 6 0.72 0.07 3.17
4 INT103900 Positive_regulation of ERCC2 7 0.58 3.47 1.78
5 INT86909 Negative_regulation of MSH2 9 0.41 12.65 1.7
6 INT107992 Gene_expression of MSH2 39 0.78 37.09 1.6
7 INT112597 Positive_regulation of Msh3 2 0.25 0 1.42
8 INT142950 Protein_catabolism of ERCC2 2 0.25 1.45 1.14
9 INT113712 Positive_regulation of Gene_expression of Msh3 2 0.43 0 1.04
10 INT86907 Negative_regulation of MSH6 8 0.33 6.76 0.93
11 INT306520 Negative_regulation of Msh3 2 0.40 0.22 0.76
12 INT92142 Binding of MSH2 5 0.46 5.64 0.75
13 INT148353 Binding of XRCC3 1 0.15 0.29 0.71
14 INT248470 Gene_expression of Ighmbp2 5 0.75 3.32 0.68
15 INT25176 Regulation of Msh2 3 0.37 0.48 0.68
16 INT130385 Gene_expression of ERCC6 7 0.77 8.36 0.63
17 INT25175 Gene_expression of Msh2 2 0.55 0.4 0.52
18 INT146545 Negative_regulation of Gene_expression of MSH2 17 0.56 18.87 0.51
19 INT134070 Binding of ERCC2 3 0.27 0.76 0.51
20 INT103901 Regulation of ERCC2 1 0.23 0.51 0.4
21 INT121185 Binding of Msh3 1 0.10 0.1 0.3
22 INT107983 Gene_expression of MSH6 6 0.51 5.57 0.27
23 INT189346 Positive_regulation of ERCC6 6 0.60 3.37 0.23
24 INT181920 Gene_expression of MSH3 2 0.50 2.54 0.18
25 INT182627 Regulation of MSH2 1 0.26 2.27 0.18
26 INT227876 Transcription of ERCC6 1 0.68 1.87 0.17
27 INT189355 Phosphorylation of ERCC6 1 0.79 1.11 0.16
28 INT184997 Gene_expression of TOP2A 6 0.63 1.65 0.15
29 INT196422 Negative_regulation of Cdk7 1 0.27 1.12 0.15
30 INT182408 Localization of ERCC6 4 0.72 2.31 0.14
31 INT236392 Regulation of Rad51 1 0.00 0.3 0.14
32 INT182623 Localization of MSH2 3 0.77 5.49 0.12
33 INT212020 Negative_regulation of RAD51D 2 0.07 1.06 0.12
34 INT182626 Localization of MSH3 1 0.22 0.77 0.12
35 INT182622 Regulation of MSH3 1 0.08 0.77 0.12
36 INT181745 Positive_regulation of MSH2 4 0.48 5.73 0.11
37 INT243228 Protein_catabolism of Ighmbp2 3 0.16 0.83 0.1
38 INT151702 Binding of ERCC6 6 0.37 1.47 0.09
39 INT227880 Positive_regulation of Transcription of ERCC6 1 0.50 0.52 0.09
40 INT15504 Positive_regulation of Msh2 1 0.33 0.15 0.09
41 INT268846 Negative_regulation of Top2a 6 0.29 3.06 0.07
42 INT200136 Negative_regulation of ERCC2 1 0.37 1.91 0.07
43 INT190034 Transcription of Ighmbp2 3 0.07 0.95 0.06
44 INT258473 Binding of TOP2A 3 0.05 1.65 0.05
45 INT333807 Localization of Rad51 1 0.24 0.52 0.05
46 INT182414 Gene_expression of RAD51 25 0.65 2.14 0.03
47 INT248475 Regulation of Ighmbp2 2 0.05 0.96 0.03
48 INT260908 Positive_regulation of Smarca4 2 0.21 0.53 0.03
49 INT291906 Positive_regulation of Negative_regulation of ERCC2 1 0.40 0 0.03
50 INT141562 Negative_regulation of ERCC6 11 0.50 3.04 0
51 INT189353 Binding of RAD51 11 0.40 0.93 0
52 INT230323 Positive_regulation of RAD51 11 0.58 0.51 0
53 INT141563 Regulation of ERCC6 6 0.59 2.54 0
54 INT230316 Localization of RAD51 5 0.67 0.07 0
55 INT235686 Gene_expression of Top2a 5 0.60 4.34 0
56 INT212022 Gene_expression of RAD51D 4 0.27 0.81 0
57 INT118827 Regulation of TOP2A 4 0.04 1.75 0
58 INT230328 Negative_regulation of RAD51 4 0.36 0 0
59 INT36301 Negative_regulation of TOP2A 3 0.57 2.66 0
60 INT107991 Positive_regulation of Gene_expression of MSH6 3 0.38 1.35 0
61 INT190020 Gene_expression of Msh2 2 0.69 0.69 0
62 INT212023 Regulation of RAD51D 2 0.05 0.34 0
63 INT268847 Binding of Top2a 2 0.24 0.6 0
64 INT212518 Localization of MSH6 2 0.10 2.66 0
65 INT230310 Gene_expression of XRCC3 2 0.32 0.4 0
66 INT190035 Binding of Msh6 2 0.28 2.72 0
67 INT227856 Regulation of Transcription of ERCC6 1 0.45 0 0
68 INT189352 Negative_regulation of Gene_expression of ERCC6 1 0.36 0 0
69 INT336756 Regulation of Transcription of Ighmbp2 1 0.03 0 0
70 INT189345 Negative_regulation of Localization of ERCC6 1 0.41 0.06 0
71 INT206928 Transcription of MSH2 1 0.52 0.4 0
72 INT306522 Negative_regulation of Gene_expression of Msh3 1 0.40 0 0
73 INT230311 Transcription of RAD51 1 0.69 0 0
74 INT182625 Positive_regulation of Localization of MSH2 1 0.45 2.47 0
75 INT296158 Negative_regulation of Rad51 1 0.17 0.11 0
76 INT308260 Positive_regulation of TOP2A 1 0.03 0.58 0
77 INT230648 Gene_expression of Cdk7 1 0.65 0.49 0
78 INT230318 Regulation of RAD51 1 0.38 0 0
79 INT256916 Regulation of Gene_expression of Top2a 1 0.47 1.2 0
80 INT212024 Positive_regulation of RAD51D 1 0.05 0.32 0
81 INT248485 Positive_regulation of Gene_expression of Ighmbp2 1 0.05 0.1 0
82 INT189344 Positive_regulation of Phosphorylation of ERCC6 1 0.58 0 0
83 INT189354 Negative_regulation of Phosphorylation of ERCC6 1 0.49 0 0
84 INT189358 Negative_regulation of Regulation of ERCC6 1 0.36 0 0
85 INT190015 Binding of Msh2 1 0.27 1.41 0
86 INT305347 Negative_regulation of Gene_expression of Msh6 1 0.25 2.22 0
87 INT211715 Negative_regulation of Gene_expression of MSH6 1 0.06 1.09 0
88 INT227866 Positive_regulation of Regulation of ERCC6 1 0.50 0.58 0
89 INT189357 Positive_regulation of Binding of ERCC6 1 0.42 0.15 0
90 INT239664 Positive_regulation of Gene_expression of TOP2A 1 0.01 0.1 0
91 INT149430 Localization of ERCC2 1 0.43 0.76 0
92 INT230322 Regulation of XRCC3 1 0.06 0.06 0
93 INT256921 Regulation of Top2a 1 0.21 1.28 0
94 INT107984 Positive_regulation of Gene_expression of MSH2 1 0.11 0 0
95 INT182624 Positive_regulation of Positive_regulation of MSH2 1 0.45 1.24 0
96 INT227883 Positive_regulation of Gene_expression of ERCC6 1 0.60 0.4 0
97 INT230301 Positive_regulation of Gene_expression of RAD51 1 0.58 0.16 0
98 INT336755 Positive_regulation of Ighmbp2 1 0.03 0.09 0
99 INT260913 Negative_regulation of Smarca4 1 0.18 0.29 0
100 INT268845 Positive_regulation of Binding of Top2a 1 0.05 0.33 0
101 INT285820 Negative_regulation of XRCC3 1 0.16 0.78 0
102 INT273916 Binding of Smarca4 1 0.01 0 0
103 INT150198 Gene_expression of ERCC8 1 0.09 0.12 0
104 INT230677 Positive_regulation of Gene_expression of Cdk7 1 0.58 0.24 0
105 INT336753 Positive_regulation of Negative_regulation of Ighmbp2 1 0.03 0.14 0
106 INT273508 Negative_regulation of Gene_expression of Top2a 1 0.21 0.17 0
107 INT227879 Regulation of Protein_catabolism of ERCC6 1 0.27 0.38 0
108 INT296159 Gene_expression of Rad51 1 0.11 0.11 0
109 INT189356 Regulation of Regulation of ERCC6 1 0.59 0 0
110 INT230652 Binding of Cdk7 1 0.31 0.09 0
111 INT304071 Binding of MSH6 1 0.28 1.11 0
112 INT337913 Binding of Ighmbp2 1 0.36 0.26 0
113 INT289818 Positive_regulation of Cdk7 1 0.04 0.05 0
114 INT336757 Negative_regulation of Ighmbp2 1 0.03 0.27 0
115 INT150197 Regulation of ERCC8 1 0.03 0.13 0
116 INT189361 Regulation of Phosphorylation of ERCC6 1 0.38 0.07 0
117 INT227875 Protein_catabolism of ERCC6 1 0.65 0.81 0
118 INT212021 Regulation of Gene_expression of RAD51D 1 0.05 0.23 0
119 INT306519 Regulation of Gene_expression of Msh3 1 0.42 0 0
120 INT230321 Regulation of Binding of RAD51 1 0.38 0 0
121 INT212025 Localization of RAD51D 1 0.08 1.29 0
122 INT305349 Gene_expression of Msh6 1 0.46 2.21 0
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