GO:0008200

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Name ion channel inhibitor activity
Categary Function
Go Slim No
Go Link GO:0008200
Unique Molecular Interactions 11
Total Molecular Interactions 12
Total Single Events 56
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for ion channel inhibitor activity. They are ordered first by their pain relevance and then by number of times they were reported for ion channel inhibitor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT166388 Binding of Gnb2l1 and Mapk1 1 0.49 0.49 1.21
2 INT166386 Mapk1 Regulation of Gene_expression of Gnb2l1 1 0.46 0.25 0.7
3 INT166387 Binding of Gnb2l1 and Mdk 1 0.30 0.24 0.61
4 INT166385 Binding of Araf and Gnb2l1 1 0.23 0.24 0.6
5 INT244050 Binding of Gnb2l1 and Prkca 1 0.01 0 0.45
6 INT134080 OPA1 Negative_regulation of Phosphorylation of Gnb2l1 1 0.03 0.22 0.34
7 INT302979 Binding of Gnb2l1 and Smpd2 1 0.07 0.71 0.09
8 INT275799 Binding of Hcrt and Lynx1 1 0.01 0.34 0.07
9 INT190738 Adcyap1 Positive_regulation of Gene_expression of Gnb2l1 1 0.08 0 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported for ion channel inhibitor activity. They are ordered first by their pain relevance and then by number of times they were reported in ion channel inhibitor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT159116 Gene_expression of Gnb2l1 12 0.77 2.79 9.49
2 INT166383 Positive_regulation of Gene_expression of Gnb2l1 1 0.69 2.19 7.02
3 INT159115 Negative_regulation of Gene_expression of Gnb2l1 3 0.42 1.33 5.59
4 INT159122 Positive_regulation of Gnb2l1 8 0.69 2.2 4.61
5 INT166381 Negative_regulation of Gnb2l1 1 0.43 0.73 2.68
6 INT159117 Regulation of Gene_expression of Gnb2l1 3 0.56 0.5 2.36
7 INT159120 Protein_catabolism of Gnb2l1 1 0.26 0.37 1.79
8 INT336708 Gene_expression of Lynx1 2 0.49 1.72 0.67
9 INT351321 Binding of Lynx1 1 0.01 0.87 0.63
10 INT166382 Positive_regulation of Positive_regulation of Gnb2l1 1 0.50 0.2 0.44
11 INT336711 Negative_regulation of Lynx1 1 0.35 0.94 0.36
12 INT134072 Negative_regulation of Phosphorylation of Gnb2l1 1 0.11 0.22 0.34
13 INT134076 Phosphorylation of Gnb2l1 1 0.22 0.22 0.3
14 INT190723 Gene_expression of Gnb2l1 1 0.17 0 0.03
15 INT337982 Transcription of Gnb2l1 1 0.20 0.83 0
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