GO:0008483

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Name transaminase activity
Categary Function
Go Slim No
Go Link GO:0008483
Unique Molecular Interactions 95
Total Molecular Interactions 127
Total Single Events 2227
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for transaminase activity. They are ordered first by their pain relevance and then by number of times they were reported for transaminase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT153728 RYBP Positive_regulation of Gpt 3 0.03 2.01 2.36
2 INT288731 Binding of Got1 and Gpt 1 0.23 1.25 1.61
3 INT167428 Il1b Positive_regulation of Localization of Gpt 1 0.43 1.31 1.11
4 INT167426 Tlr4 Positive_regulation of Localization of Gpt 1 0.25 1.26 1.1
5 INT52596 B4GALNT1 Positive_regulation of Gpt 1 0.00 0 0.95
6 INT168026 Positive_regulation of HBG2 Regulation of Gpt 1 0.01 0.15 0.89
7 INT168019 Ldha Regulation of Gpt 1 0.01 0.15 0.88
8 INT168018 Positive_regulation of Ldha Regulation of Gpt 1 0.01 0.15 0.88
9 INT168025 HBG2 Regulation of Gpt 1 0.01 0.15 0.88
10 INT160412 Tat Positive_regulation of Transcription of Nos2 1 0.37 0.98 0.86
11 INT160413 Tat Positive_regulation of Gene_expression of Cd40lg 1 0.50 0.98 0.86
12 INT151008 Gpt Positive_regulation of Gene_expression of alp 1 0.08 0.07 0.83
13 INT160411 Tat Positive_regulation of Il6 1 0.17 0.89 0.8
14 INT63588 Aap Positive_regulation of Positive_regulation of Got1 1 0.31 0.6 0.79
15 INT63589 Binding of Got1 and Gpt 1 0.36 0.56 0.74
16 INT51933 MSMB Negative_regulation of Positive_regulation of Gpt 1 0.18 0.33 0.74
17 INT150863 Grtp1 Negative_regulation of Gpt 1 0.09 0.58 0.71
18 INT160414 Hivan1 Positive_regulation of Tat 1 0.15 0.84 0.66
19 INT115764 Binding of Rbm39 and Tat 1 0.00 0 0.66
20 INT152766 TAT Positive_regulation of Positive_regulation of MYLK 1 0.44 0.67 0.61
21 INT112869 Aap Positive_regulation of Gpt 2 0.26 0.75 0.6
22 INT152765 TAT Regulation of Positive_regulation of MYLK 1 0.40 0.66 0.6
23 INT288729 Positive_regulation of Binding of Got1 and Gpt 1 0.25 0.61 0.49
24 INT90252 Binding of PPBP and TAT 1 0.39 5.55 0.48
25 INT90262 Binding of TAT and Pf4 1 0.03 5.64 0.48
26 INT11651 Nlrp1a Negative_regulation of Gpt 1 0.12 0.24 0.47
27 INT101327 Binding of Cnr1 and Amt 1 0.25 0 0.47
28 INT161082 asp3 Regulation of Gpt 1 0.23 0.67 0.4
29 INT22921 Ccl4 Positive_regulation of Gpt 1 0.00 0.24 0.39
30 INT38305 Binding of DACT1 and Gpt 1 0.01 0.43 0.39
31 INT22920 Negative_regulation of Ccl4 Positive_regulation of Gpt 1 0.00 0.24 0.39
32 INT91485 ZNF404 Negative_regulation of AMT 1 0.01 0 0.35
33 INT310934 Positive_regulation of Tgm2 Positive_regulation of Binding of IGHE 1 0.14 1.33 0.34
34 INT303127 Gpt Positive_regulation of Gene_expression of Il6 1 0.09 4.38 0.34
35 INT355153 Gpt Positive_regulation of Positive_regulation of Ldha 1 0.02 1.33 0.3
36 INT96102 Binding of TAT and Selp 1 0.04 0.7 0.3
37 INT96082 Binding of SELP and TAT 1 0.40 0.69 0.3
38 INT343569 Negative_regulation of Synm Positive_regulation of Gpt 1 0.01 0.96 0.29
39 INT355152 Gpt Positive_regulation of Gene_expression of Ldha 1 0.02 1.26 0.29
40 INT96099 Binding of TAT and F2 1 0.01 0.68 0.29
41 INT343570 Synm Positive_regulation of Gpt 1 0.01 1.28 0.28
42 INT91449 Gpt Positive_regulation of Got1 1 0.01 3.26 0.26
43 INT101326 Negative_regulation of Binding of Cnr1 and Amt 1 0.29 0 0.25
44 INT292621 Binding of IL6 and Gpt 1 0.01 3.88 0.24
45 INT308816 Gpt Positive_regulation of Tnf 1 0.08 0.72 0.24
46 INT288732 Got1 Positive_regulation of Gene_expression of Gpt 1 0.31 0.52 0.23
47 INT304964 Binding of AMT and PTK2B 1 0.23 0.78 0.18
48 INT185360 Binding of PCS and Gpt 1 0.04 0.56 0.18
49 INT310932 Binding of Tgm2 and Serpinb1a 1 0.04 0.87 0.17
50 INT20202 Binding of TAT and Fgf12 1 0.01 1.5 0.17
51 INT20203 Positive_regulation of Binding of TAT and Fgf12 1 0.01 1.51 0.17
52 INT191880 Tlr4 Positive_regulation of Gene_expression of Gpt 1 0.11 0.09 0.16
53 INT191878 Pbsn Positive_regulation of Gene_expression of Gpt 1 0.03 0.09 0.16
54 INT303122 Nos2 Positive_regulation of Gene_expression of Gpt 1 0.37 1.86 0.16
55 INT303121 Gpt Positive_regulation of Gene_expression of Gpt 1 0.25 1.86 0.16
56 INT303129 Nos2 Positive_regulation of Gene_expression of Gpt 1 0.17 1.86 0.16
57 INT127966 GPT Positive_regulation of SLC17A5 1 0.50 1.81 0.14
58 INT250910 Thbs2 Regulation of Tgm2 1 0.04 0.3 0.13
59 INT11632 Binding of SERPINE1 and TAT 1 0.11 0.78 0.13
60 INT270667 Binding of Bcat1 and Prh1 1 0.01 0.89 0.12
61 INT3751 Binding of GOT1 and PIK3C2A 1 0.08 0.68 0.12
62 INT3752 Binding of GOT1 and LDHA 1 0.11 0.68 0.12
63 INT310311 Tlr4 Positive_regulation of Gpt 1 0.05 1.15 0.12
64 INT156749 Gpt Positive_regulation of Gene_expression of Gpt2 1 0.50 0.22 0.1
65 INT156751 Gpt2 Positive_regulation of Gpt 1 0.12 0.21 0.1
66 INT156750 Gpt Positive_regulation of Gpt 1 0.27 0.22 0.1
67 INT73585 TAT Positive_regulation of Mb 1 0.15 0.64 0.09
68 INT185359 Gpt Regulation of PCS 1 0.03 0.33 0.09
69 INT303123 Gpt Positive_regulation of Gene_expression of Mpo 1 0.22 0.99 0.08
70 INT87808 Binding of Gpt and HCC 3 0.04 5.09 0.07
71 INT310933 Il6 Positive_regulation of Tgm2 1 0.00 0.55 0.07
72 INT275503 Ccl4 Positive_regulation of Gpt 1 0.20 0 0.04
73 INT353549 Pck1 Regulation of Gene_expression of Gpt 1 0.00 0 0
74 INT282294 Binding of Gpt and BPIFA4P 1 0.02 0.47 0
75 INT191699 Binding of TAT and TAR 1 0.03 0.75 0
76 INT310280 Gpt Positive_regulation of SLPI 1 0.30 0.43 0
77 INT232817 Mocos Negative_regulation of Positive_regulation of Gpt 1 0.29 0.34 0
78 INT191700 Positive_regulation of Binding of TAT and TAR 1 0.04 0.76 0
79 INT284372 Binding of ABCA1 and AMT 1 0.00 0 0
80 INT229433 Atp6v0a2 Negative_regulation of Positive_regulation of Gpt 1 0.00 0.32 0
81 INT261963 Binding of Cacna1a and Tgm2 1 0.08 1.19 0
82 INT191698 Binding of TAT and SORBS1 1 0.01 1.08 0
83 INT276300 TAT Regulation of Gene_expression of VEGFA 1 0.14 1.58 0
84 INT284391 Binding of AMT and Alms1 1 0.00 0 0
85 INT353550 Pck1 Regulation of Gpt 1 0.00 0 0
86 INT275501 Aap Positive_regulation of Positive_regulation of Gpt 1 0.12 0.23 0
87 INT300891 Binding of Atp9a and Tgm2 1 0.00 0.39 0
88 INT244709 Binding of Ldha and Gpt 1 0.01 1.32 0
89 INT300892 Binding of Atp8a1 and Tgm2 1 0.01 0.68 0
90 INT329644 Galnt5 Positive_regulation of Gpt 1 0.01 0.54 0
91 INT329643 Regulation of Galnt5 Positive_regulation of Gpt 1 0.01 0.54 0
92 INT88689 Binding of HBE1 and Gpt 1 0.00 0.71 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for transaminase activity. They are ordered first by their pain relevance and then by number of times they were reported in transaminase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82
2 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36
3 INT11650 Negative_regulation of Gpt 122 0.59 69.15 30.36
4 INT3286 Positive_regulation of Gpt 90 0.69 45.08 28.34
5 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38
6 INT3206 Positive_regulation of Got1 39 0.69 19.36 17.02
7 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94
8 INT17565 Regulation of Gpt 85 0.60 43.64 13.68
9 INT22213 Localization of Gpt 52 0.78 34.05 12.94
10 INT11649 Negative_regulation of Positive_regulation of Gpt 25 0.59 13.94 10.87
11 INT62166 Positive_regulation of Gene_expression of Gpt 64 0.50 39.13 9.69
12 INT3287 Gene_expression of Gpt 50 0.75 23.69 8.57
13 INT22214 Positive_regulation of Localization of Gpt 14 0.62 8.42 7.89
14 INT22919 Negative_regulation of Gpt 18 0.55 6.84 7.4
15 INT17779 Negative_regulation of Got1 12 0.40 3.5 6.08
16 INT8866 Positive_regulation of TAT 30 0.67 18.06 5.57
17 INT22943 Positive_regulation of Positive_regulation of Gpt 23 0.47 16.09 5.55
18 INT114311 Negative_regulation of Gene_expression of Gpt 33 0.38 17.83 4.94
19 INT504 Gene_expression of GPT 42 0.75 27.54 3.99
20 INT12189 Localization of Gpt 8 0.73 3.63 3.92
21 INT14717 Gene_expression of TAT 20 0.75 10.67 3.66
22 INT38303 Binding of Gpt 21 0.47 15.84 3.43
23 INT2135 Regulation of Gpt 13 0.44 2.17 3.03
24 INT45971 Negative_regulation of GOT1 9 0.51 6.2 2.84
25 INT49862 Negative_regulation of Positive_regulation of Gpt 8 0.41 3.49 2.6
26 INT4419 Gene_expression of GOT1 20 0.65 22.53 2.53
27 INT56918 Negative_regulation of TAT 11 0.57 5.92 2.44
28 INT79281 Gene_expression of Tgm2 14 0.76 7.46 2.37
29 INT38095 Negative_regulation of Positive_regulation of Got1 3 0.20 1.97 2.16
30 INT63598 Localization of Got1 2 0.70 0.87 2.11
31 INT46668 Negative_regulation of Localization of Gpt 8 0.42 4.61 2.08
32 INT17274 Gene_expression of Got1 11 0.58 3.98 2
33 INT45564 Positive_regulation of Positive_regulation of Gpt 5 0.49 1.85 1.76
34 INT53451 Regulation of TAT 6 0.44 3.07 1.61
35 INT63599 Positive_regulation of Localization of Got1 2 0.46 0.67 1.57
36 INT22159 Gene_expression of AMT 11 0.75 2.19 1.5
37 INT97212 Regulation of Positive_regulation of Gpt 4 0.43 3.95 1.47
38 INT91491 Negative_regulation of AMT 6 0.39 1.93 1.32
39 INT63223 Transcription of Gpt 4 0.65 3.38 1.27
40 INT36330 Positive_regulation of Positive_regulation of GOT1 4 0.32 4.42 1.26
41 INT17099 Regulation of GPT 9 0.44 5.5 1.2
42 INT101323 Negative_regulation of Amt 1 0.40 0 1.14
43 INT166071 Positive_regulation of Negative_regulation of Gpt 2 0.41 1.49 1.12
44 INT3288 Positive_regulation of Gene_expression of Gpt 9 0.49 5.55 1.1
45 INT63597 Negative_regulation of Localization of Got1 2 0.43 0.49 1.06
46 INT3529 Regulation of GOT1 6 0.52 2.4 1.01
47 INT141798 Negative_regulation of Transcription of Gpt 1 0.40 0.87 0.88
48 INT96678 Binding of TAT 3 0.47 6.75 0.85
49 INT207421 Positive_regulation of Gene_expression of GPT 9 0.49 5.62 0.83
50 INT104390 Positive_regulation of Positive_regulation of Got1 3 0.26 1.34 0.83
51 INT141591 Negative_regulation of Positive_regulation of GPT 2 0.42 0.83 0.8
52 INT46881 Negative_regulation of Negative_regulation of Gpt 1 0.38 0 0.8
53 INT12099 Localization of GOT1 2 0.35 2.54 0.72
54 INT344781 Transcription of Tgm2 1 0.28 1.55 0.68
55 INT34663 Protein_catabolism of Gpt 2 0.68 0.99 0.65
56 INT12192 Negative_regulation of Localization of Gpt 1 0.39 0.45 0.64
57 INT103191 Phosphorylation of Gpt 3 0.78 2.35 0.63
58 INT103194 Positive_regulation of Phosphorylation of Gpt 1 0.48 1.94 0.63
59 INT167680 Localization of Tat 1 0.73 0.84 0.58
60 INT61110 Positive_regulation of Binding of Gpt 2 0.50 1.13 0.56
61 INT51485 Localization of TAT 3 0.78 2.18 0.55
62 INT11867 Positive_regulation of Positive_regulation of TAT 2 0.49 2.02 0.54
63 INT2812 Transcription of GPT 2 0.67 1.18 0.52
64 INT163114 Positive_regulation of Gene_expression of GOT1 7 0.24 8.93 0.5
65 INT56598 Transcription of Gpt 4 0.34 1.65 0.5
66 INT22158 Regulation of AMT 1 0.26 0.45 0.45
67 INT55807 Negative_regulation of GPT 4 0.42 4.11 0.44
68 INT47387 Negative_regulation of Positive_regulation of GOT1 2 0.26 1.04 0.43
69 INT79282 Positive_regulation of Tgm2 5 0.67 5.15 0.39
70 INT344782 Positive_regulation of Transcription of Tgm2 1 0.24 0.67 0.36
71 INT70552 Regulation of Gene_expression of Got1 1 0.16 0.18 0.36
72 INT137056 Regulation of Gene_expression of Gpt 9 0.39 3.92 0.33
73 INT56600 Positive_regulation of Transcription of Gpt 1 0.12 0.1 0.32
74 INT46443 Regulation of Positive_regulation of Gpt 1 0.27 0.52 0.3
75 INT274704 Localization of GPT 5 0.73 3.91 0.29
76 INT79280 Positive_regulation of Gene_expression of Tgm2 1 0.19 1.79 0.27
77 INT335119 Regulation of Transcription of GPT 1 0.08 0.56 0.27
78 INT136660 Regulation of Gene_expression of Gpt 1 0.14 0.24 0.25
79 INT330595 Regulation of Localization of Gpt 1 0.02 1.05 0.25
80 INT44540 Binding of GPT 3 0.36 6.14 0.23
81 INT188319 Regulation of Negative_regulation of Gpt 2 0.09 1.91 0.21
82 INT55871 Binding of GOT1 1 0.04 2.22 0.19
83 INT292617 Negative_regulation of Binding of Gpt 2 0.03 1.97 0.18
84 INT159088 Gene_expression of Tat 1 0.75 1.43 0.15
85 INT154678 Positive_regulation of Gene_expression of TAT 2 0.49 1.7 0.12
86 INT342900 Negative_regulation of Regulation of GOT1 1 0.04 0.42 0.12
87 INT250897 Negative_regulation of Tgm2 1 0.05 0.25 0.12
88 INT298577 Negative_regulation of Negative_regulation of GPT 1 0.02 1.76 0.12
89 INT270632 Binding of Bcat1 1 0.34 0.88 0.12
90 INT298572 Negative_regulation of Negative_regulation of Gpt 1 0.03 1.76 0.12
91 INT180027 Binding of Tgm2 6 0.35 4.06 0.11
92 INT295451 Negative_regulation of Gene_expression of Gpt 4 0.38 1.26 0.1
93 INT34664 Binding of Gpt 2 0.36 1.21 0.09
94 INT342261 Positive_regulation of Localization of GPT 2 0.49 0.95 0.07
95 INT273457 Regulation of Gene_expression of Tgm2 2 0.60 0.88 0.07
96 INT330596 Protein_catabolism of Gpt 1 0.05 0.13 0.07
97 INT38981 Positive_regulation of Gene_expression of Got1 1 0.33 0.65 0.07
98 INT180025 Regulation of Tgm2 1 0.20 1.59 0.05
99 INT197485 Regulation of Positive_regulation of GOT1 1 0.01 0.44 0.04
100 INT197486 Positive_regulation of Regulation of GOT1 1 0.01 0.44 0.04
101 INT191701 Regulation of Binding of TAT 1 0.26 0.43 0.04
102 INT222142 Binding of AMT 5 0.20 0.36 0.03
103 INT273143 Negative_regulation of Tat 1 0.01 2.3 0
104 INT329631 Regulation of Regulation of Gpt 1 0.15 0.53 0
105 INT344588 Negative_regulation of Gene_expression of GPT 1 0.41 0.62 0
106 INT284386 Positive_regulation of Gene_expression of AMT 1 0.07 0 0
107 INT284387 Positive_regulation of AMT 1 0.09 0.08 0
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