GO:0009405

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Name pathogenesis
Categary Process
Go Slim No
Go Link GO:0009405
Unique Molecular Interactions 32
Total Molecular Interactions 35
Total Single Events 322
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for pathogenesis. They are ordered first by their pain relevance and then by number of times they were reported for pathogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT73467 PTPLA Positive_regulation of Transcription of Myc 1 0.29 0.97 0.94
2 INT116269 Binding of Myc and Mycbp2 1 0.19 0.5 0.87
3 INT144547 Binding of Mecp2 and Sin3a 1 0.40 0.87 0.76
4 INT135361 Prr14 Positive_regulation of Mecp2 1 0.24 0.15 0.64
5 INT135363 Mecp2 Positive_regulation of Mbd1 1 0.50 0.15 0.64
6 INT247265 Mecp2 Regulation of Fos 1 0.25 0.38 0.52
7 INT135360 Binding of Mecp2 and Aadac 1 0.03 0.19 0.51
8 INT280479 Binding of Mecp2 and Sin3a 1 0.00 1.54 0.35
9 INT327300 Binding of Hnrnpd and Myc 1 0.12 1.02 0.25
10 INT280475 Binding of Bdnf and Mecp2 1 0.11 0.92 0.22
11 INT280478 Mecp2 Negative_regulation of Gene_expression of Bdnf 1 0.13 0.94 0.22
12 INT280487 Negative_regulation of Binding of Mecp2 and Sin3a 1 0.00 0.77 0.18
13 INT318969 Mecp2 Regulation of Gene_expression of Bdnf 1 0.17 0.28 0.17
14 INT116268 Binding of Myc and Acsl1 1 0.08 0.19 0.16
15 INT247266 Binding of Mecp2 and Fos 1 0.30 0.18 0.13
16 INT247267 Binding of Egr1 and Mecp2 1 0.12 0.18 0.13
17 INT201722 Myc Regulation of Gene_expression of Ccnd1 1 0.03 0.79 0.13
18 INT320261 Binding of Myc and Ntrk2 1 0.01 0.36 0.13
19 INT201791 JUP Regulation of Gene_expression of Myc 1 0.49 0.8 0.13
20 INT173200 PPA1 Positive_regulation of Myc 1 0.08 0.5 0.12
21 INT247264 Mecp2 Positive_regulation of Gtf2i 1 0.02 0 0.08
22 INT248209 Camk2a Positive_regulation of Phosphorylation of Mecp2 1 0.52 0 0.08
23 INT253023 Binding of PTTG1 and Myc 1 0.16 0.22 0.04
24 INT302291 Positive_regulation of EGFR Positive_regulation of Myc 1 0.18 1.3 0.04
25 INT202270 Pttg1 Positive_regulation of Myc 1 0.28 0.84 0.03
26 INT173199 CNOT4 Regulation of Regulation of Myc 1 0.01 0.66 0.03
27 INT225550 Binding of Mybbp1a and Carm1 1 0.06 0 0
28 INT329898 MIRLET7C Regulation of Myc 1 0.49 0.62 0
29 INT315159 Erbb2 Negative_regulation of Myc 1 0.43 0.84 0
30 INT322597 Myc Negative_regulation of Gene_expression of CFLAR 1 0.11 1.35 0
31 INT315160 Egfr Negative_regulation of Myc 1 0.45 0.84 0
32 INT303168 Binding of Myc and Dlgap1 1 0.10 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for pathogenesis. They are ordered first by their pain relevance and then by number of times they were reported in pathogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT29988 Gene_expression of Mecp2 27 0.78 5.45 9.47
2 INT144539 Phosphorylation of Mecp2 3 0.82 6.18 6.2
3 INT135359 Positive_regulation of Mecp2 4 0.70 4.35 6.05
4 INT17892 Gene_expression of Myc 57 0.75 36.37 5.82
5 INT318967 Gene_expression of Mecp2 9 0.77 11.52 3.55
6 INT36886 Transcription of Myc 6 0.69 3.16 2.86
7 INT73460 Positive_regulation of Gene_expression of Myc 26 0.67 20.44 2.61
8 INT144541 Negative_regulation of Gene_expression of Mecp2 3 0.42 1.43 1.9
9 INT247261 Negative_regulation of Mecp2 1 0.42 1.71 1.78
10 INT144538 Regulation of Phosphorylation of Mecp2 2 0.45 1.87 1.77
11 INT135355 Binding of Mecp2 4 0.37 0.83 1.72
12 INT144542 Positive_regulation of Phosphorylation of Mecp2 2 0.68 1.43 1.5
13 INT318963 Positive_regulation of Mecp2 5 0.50 1.78 1.49
14 INT116265 Binding of Myc 9 0.36 4.28 1.36
15 INT247263 Regulation of Mecp2 4 0.60 1.31 1.32
16 INT280467 Negative_regulation of Mecp2 5 0.59 3.33 1.21
17 INT71848 Positive_regulation of Transcription of Myc 1 0.67 0.16 1.11
18 INT102070 Regulation of Gene_expression of Myc 4 0.60 2.68 0.96
19 INT17894 Regulation of Myc 10 0.60 5.65 0.93
20 INT247262 Negative_regulation of Positive_regulation of Mecp2 1 0.42 0.85 0.8
21 INT318962 Negative_regulation of Gene_expression of Mecp2 2 0.43 0.5 0.7
22 INT183395 Localization of Mecp2 4 0.75 1.76 0.69
23 INT280463 Binding of Mecp2 3 0.37 4 0.63
24 INT247256 Negative_regulation of Phosphorylation of Mecp2 1 0.57 0.63 0.52
25 INT247259 Positive_regulation of Gene_expression of Mecp2 1 0.68 0.13 0.46
26 INT280468 Positive_regulation of Localization of Mecp2 3 0.50 1.76 0.45
27 INT318964 Negative_regulation of Localization of Mecp2 1 0.43 0.53 0.43
28 INT90354 Negative_regulation of Myc 6 0.57 4.24 0.4
29 INT280462 Positive_regulation of Phosphorylation of Mecp2 1 0.12 1.69 0.37
30 INT135356 Positive_regulation of Binding of Mecp2 1 0.50 0.1 0.36
31 INT338882 Regulation of Regulation of Mecp2 1 0.24 0.56 0.29
32 INT248208 Phosphorylation of Mecp2 3 0.82 1.17 0.26
33 INT187547 Localization of Myc 1 0.68 0.92 0.26
34 INT187548 Regulation of Transcription of Myc 1 0.44 0.68 0.26
35 INT102071 Negative_regulation of Gene_expression of Myc 8 0.57 3.5 0.22
36 INT247260 Regulation of Gene_expression of Mecp2 1 0.60 0.06 0.21
37 INT17893 Positive_regulation of Myc 4 0.67 3.28 0.06
38 INT201778 Positive_regulation of Phosphorylation of Myc 1 0.49 1.02 0.05
39 INT201776 Phosphorylation of Myc 1 0.80 1.01 0.05
40 INT332334 Regulation of Binding of Myc 1 0.44 0 0.04
41 INT142711 Negative_regulation of Transcription of Myc 1 0.41 0.45 0
42 INT320943 Negative_regulation of Phosphorylation of Mecp2 1 0.43 0.33 0
43 INT301444 Positive_regulation of Carm1 1 0.04 0 0
44 INT301437 Regulation of Carm1 1 0.02 0.06 0
45 INT320939 Transcription of Mecp2 1 0.69 0.2 0
46 INT328132 Regulation of Mecp2 1 0.40 1 0
47 INT320952 Regulation of Gene_expression of Mecp2 1 0.45 0.87 0
48 INT320949 Negative_regulation of Binding of Mecp2 1 0.43 0.21 0
49 INT225388 Binding of Carm1 1 0.17 0 0
50 INT320950 Positive_regulation of Gene_expression of Mecp2 1 0.50 1.24 0
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