GO:0010389

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Latest revision as of 05:27, 27 January 2013

Name regulation of G2/M transition of mitotic cell cycle
Categary Process
Go Slim No
Go Link GO:0010389
Unique Molecular Interactions 48
Total Molecular Interactions 67
Total Single Events 747
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

[edit] Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of G2/M transition of mitotic cell cycle. They are ordered first by their pain relevance and then by number of times they were reported for regulation of G2/M transition of mitotic cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT338167 Binding of CDKN2A and MC1R 1 0.42 6.14 5.76
2 INT162163 CDKN2A Positive_regulation of PLD2 1 0.24 0 1.24
3 INT69307 Prkcq Negative_regulation of TH1L 1 0.00 0.98 0.98
4 INT158032 Binding of CDKN2A and KRT20 1 0.28 0.59 0.4
5 INT204071 HP Positive_regulation of Gene_expression of CDKN2A 1 0.00 3.48 0.34
6 INT130803 MC1R Regulation of Positive_regulation of Cdkn2a 1 0.17 0.82 0.34
7 INT329954 Binding of PRKCQ and SNRNP70 1 0.07 0.65 0.33
8 INT147593 Binding of CDK4 and CDKN2A 1 0.42 0.23 0.26
9 INT147592 Positive_regulation of Binding of CDK4 and CDKN2A 1 0.44 0.23 0.26
10 INT136855 Arf5 Positive_regulation of Cdkn2a 1 0.07 1.8 0.15
11 INT314856 Binding of Cdc7 and Cdkn2a 1 0.28 1.34 0.14
12 INT302146 CDKN2A Regulation of CDKN1B 1 0.11 0.51 0.14
13 INT302144 CDKN2A Regulation of CDKN1A 1 0.11 0.51 0.14
14 INT314852 Binding of Cdkn2a and Tgfbr3 1 0.28 1.15 0.14
15 INT15902 PKIA Negative_regulation of Positive_regulation of Prkaca 1 0.10 0 0.1
16 INT302178 CDKN1C Regulation of CDKN2A 1 0.09 0.26 0.08
17 INT302158 CDKN1A Regulation of CDKN2A 1 0.04 0.26 0.08
18 INT136856 Cdkn2a Positive_regulation of Arf5 1 0.01 0.9 0.08
19 INT110855 Pkia Negative_regulation of Egf 1 0.15 1.2 0.08
20 INT302139 LAMTOR1 Regulation of CDKN2A 1 0.08 0.26 0.08
21 INT302157 MRPL28 Regulation of CDKN2A 1 0.09 0.26 0.08
22 INT302148 IFI27 Regulation of CDKN2A 1 0.11 0.26 0.08
23 INT204073 Binding of Cdkn2a and Cdk4 1 0.02 0.78 0.05
24 INT204072 Binding of Cdkn2a and Cdk6 1 0.02 0.78 0.05
25 INT244049 Positive_regulation of Binding of Car2 and Camk2d 1 0.01 0 0.03
26 INT314677 TP53 Regulation of Positive_regulation of CDKN2A 1 0.27 0.97 0.03
27 INT244042 Binding of Car2 and Camk2d 1 0.01 0 0.03
28 INT225228 Binding of Cdk4 and Cdkn2a 1 0.21 1.24 0
29 INT329680 BMI1 Negative_regulation of Gene_expression of CDKN2A 1 0.15 1.14 0
30 INT329676 CBX7 Regulation of Localization of CDKN2A 1 0.51 2.4 0
31 INT215707 Cdkn2a Negative_regulation of Cdkn1b 1 0.01 0 0
32 INT246914 Binding of CDKN2A and Ifng 1 0.01 0.71 0
33 INT311404 Binding of CDKN2A and Celf1 1 0.32 0.07 0
34 INT185281 Binding of CDK6 and CDKN2A 1 0.29 0.87 0
35 INT204234 Binding of CDKN2A and TP53 1 0.43 1.27 0
36 INT225229 Binding of Cdk6 and Cdkn2a 1 0.19 1.25 0
37 INT353437 Negative_regulation of Trp53 Positive_regulation of Gene_expression of Cdkn2a 1 0.24 0.59 0
38 INT184956 ID1 Negative_regulation of CDKN2A 1 0.42 0.21 0
39 INT204078 Binding of CDKN2A and Cdk4 1 0.15 0.72 0
40 INT215699 Cdkn2a Negative_regulation of Cdkn1c 1 0.01 0 0
41 INT215696 Cdkn2a Negative_regulation of Kras 1 0.00 0 0
42 INT329677 CDKN2A Regulation of CBX7 1 0.31 2.23 0
43 INT247427 CDKN2A Negative_regulation of Negative_regulation of RB1 1 0.07 1.16 0
44 INT204077 Binding of CDKN2A and Cdk6 1 0.15 0.72 0
45 INT314685 TBX2 Negative_regulation of CDKN2A 1 0.32 1.16 0
46 INT329679 CBX7 Regulation of CDKN2A 1 0.31 4.18 0
47 INT314680 Positive_regulation of TBX2 Negative_regulation of CDKN2A 1 0.34 1.16 0
48 INT311403 CDKN2A Regulation of Celf1 1 0.41 0.14 0

[edit] Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of G2/M transition of mitotic cell cycle. They are ordered first by their pain relevance and then by number of times they were reported in regulation of G2/M transition of mitotic cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT94774 Regulation of CDKN2A 43 0.60 44.41 13.99
2 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61
3 INT92138 Binding of CDKN2A 28 0.37 25.64 7.47
4 INT125467 Positive_regulation of Gene_expression of CDKN2A 35 0.63 39.07 5.56
5 INT13295 Positive_regulation of Cdkn2a 18 0.68 13.02 5.47
6 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38
7 INT78471 Regulation of Gene_expression of CDKN2A 13 0.45 12.52 3.28
8 INT78248 Negative_regulation of Cdkn2a 17 0.59 15.15 2.8
9 INT63846 Gene_expression of Prkcq 1 0.73 1.11 2.58
10 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48
11 INT338170 Regulation of Regulation of CDKN2A 1 0.44 0.96 2.46
12 INT94772 Gene_expression of Cdkn2a 14 0.75 8.25 2.04
13 INT26415 Regulation of Phosphorylation of PKIA 1 0.01 0.06 2.04
14 INT26417 Phosphorylation of PKIA 1 0.02 0.06 2.04
15 INT78470 Negative_regulation of Gene_expression of CDKN2A 14 0.59 14.44 1.38
16 INT63849 Regulation of Gene_expression of Prkcq 1 0.58 0.62 1.24
17 INT63847 Regulation of Prkcq 1 0.42 0.5 1.23
18 INT63856 Positive_regulation of Gene_expression of Prkcq 1 0.47 0.53 1.16
19 INT42104 Regulation of Cdkn2a 4 0.44 5.67 1.06
20 INT338168 Positive_regulation of Binding of CDKN2A 1 0.49 0.52 0.94
21 INT89669 Negative_regulation of Positive_regulation of Prkcq 1 0.08 0.23 0.87
22 INT89668 Positive_regulation of Prkcq 1 0.09 0.22 0.86
23 INT144429 Positive_regulation of Cdkn2a 7 0.58 4.05 0.78
24 INT129115 Negative_regulation of Cdkn2a 16 0.50 17.03 0.76
25 INT126355 Negative_regulation of Camk2d 1 0.49 0.23 0.63
26 INT251026 Negative_regulation of Phosphorylation of CDKN2A 5 0.42 5.02 0.62
27 INT177886 Positive_regulation of Gene_expression of Cdkn2a 3 0.67 3.42 0.62
28 INT147598 Negative_regulation of Positive_regulation of CDKN2A 3 0.41 1.47 0.59
29 INT243933 Gene_expression of Camk2d 1 0.10 0 0.55
30 INT242011 Localization of Cdkn2a 4 0.73 2.49 0.54
31 INT144701 Gene_expression of Cdkn2a 15 0.75 8.42 0.53
32 INT144431 Positive_regulation of Transcription of Cdkn2a 1 0.41 1.11 0.51
33 INT144426 Transcription of Cdkn2a 1 0.42 1.11 0.51
34 INT63850 Negative_regulation of Prkcq 1 0.40 0 0.46
35 INT220088 Positive_regulation of Positive_regulation of CDKN2A 4 0.49 4.04 0.44
36 INT252657 Positive_regulation of Phosphorylation of CDKN2A 2 0.45 3.09 0.42
37 INT42105 Regulation of Positive_regulation of Cdkn2a 1 0.44 0.33 0.42
38 INT190866 Phosphorylation of Camk2d 1 0.13 0.05 0.4
39 INT196323 Localization of Cdkn2a 8 0.73 9.1 0.32
40 INT251025 Phosphorylation of CDKN2A 4 0.61 3.19 0.32
41 INT110852 Binding of Pkia 1 0.12 1.04 0.3
42 INT228477 Positive_regulation of Gene_expression of Cdkn2a 2 0.11 1.3 0.29
43 INT15899 Gene_expression of PKIA 1 0.61 0 0.28
44 INT184624 Localization of CDKN2A 8 0.74 7.87 0.25
45 INT238494 Regulation of Transcription of CDKN2A 1 0.16 5.62 0.25
46 INT241687 Binding of Cdkn2a 5 0.31 5.26 0.18
47 INT147149 Transcription of CDKN2A 8 0.67 6.85 0.15
48 INT225216 Negative_regulation of Negative_regulation of Cdkn2a 1 0.42 3.16 0.15
49 INT24239 Positive_regulation of Pkia 1 0.18 0.31 0.12
50 INT24243 Phosphorylation of Pkia 1 0.22 0.33 0.12
51 INT112001 Binding of Cdkn2a 1 0.24 0.35 0.1
52 INT273604 Regulation of Negative_regulation of Cdkn2a 1 0.12 0.68 0.09
53 INT110853 Negative_regulation of Pkia 1 0.14 1.19 0.08
54 INT315215 Negative_regulation of Binding of Cdkn2a 1 0.35 0.11 0.05
55 INT243944 Positive_regulation of Gene_expression of Camk2d 1 0.07 0 0.03
56 INT94773 Negative_regulation of Gene_expression of Cdkn2a 3 0.41 0.65 0
57 INT282090 Regulation of Cdkn2a 2 0.33 2.02 0
58 INT308355 Negative_regulation of Gene_expression of Cdkn2a 2 0.48 1.42 0
59 INT147151 Positive_regulation of Negative_regulation of CDKN2A 2 0.47 1.74 0
60 INT308400 Negative_regulation of Regulation of CDKN2A 1 0.40 0.87 0
61 INT172979 Regulation of Negative_regulation of CDKN2A 1 0.44 0.57 0
62 INT281254 Negative_regulation of Negative_regulation of CDKN2A 1 0.08 1.44 0
63 INT147147 Positive_regulation of Transcription of CDKN2A 1 0.49 0 0
64 INT185285 Negative_regulation of Transcription of CDKN2A 1 0.43 1.12 0
65 INT184623 Positive_regulation of Localization of CDKN2A 1 0.04 0.86 0
66 INT247424 Transcription of Cdkn2a 1 0.47 0.82 0
67 INT355162 Regulation of Localization of CDKN2A 1 0.40 1.13 0
68 INT247425 Regulation of Transcription of Cdkn2a 1 0.18 0.82 0
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