GO:0015030

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Name Cajal body
Categary Component
Go Slim No
Go Link GO:0015030
Unique Molecular Interactions 107
Total Molecular Interactions 178
Total Single Events 773
Pain Genes Associated 23

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for Cajal body. They are ordered first by their pain relevance and then by number of times they were reported for Cajal body. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT106676 Binding of Trpv1 and Phax 18 0.34 4.19 12.36
2 INT140659 Phax Positive_regulation of Trpv1 3 0.49 0.68 2.18
3 INT167530 Phax Regulation of Gene_expression of Trpv1 1 0.16 0.86 2.05
4 INT262558 Phax Positive_regulation of Trpv1 1 0.01 1.26 1.92
5 INT50706 Phax Positive_regulation of Localization of Trib3 1 0.04 0.28 1.38
6 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27
7 INT116892 Binding of TRPV1 and Phax 4 0.00 0.1 1.24
8 INT283934 Phax Negative_regulation of Positive_regulation of Mapk14 1 0.03 2.06 1.09
9 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02
10 INT85485 Phax Regulation of Gene_expression of Cck 1 0.07 0.61 0.91
11 INT306831 Positive_regulation of Binding of E2F4 and NOLC1 1 0.10 0.46 0.85
12 INT140660 Phax Negative_regulation of Trpv1 2 0.08 0.58 0.84
13 INT306826 Binding of E2F4 and NOLC1 1 0.08 0.41 0.84
14 INT73462 PTPLA Regulation of Gene_expression of SART1 1 0.00 0.79 0.82
15 INT193287 Phax Regulation of STH 1 0.00 0.16 0.81
16 INT193279 Phax Regulation of Fth1 1 0.01 0.16 0.81
17 INT193275 Phax Regulation of Pth 1 0.01 0.16 0.81
18 INT193274 Phax Regulation of Brs3 1 0.00 0 0.8
19 INT281651 Phax Positive_regulation of Gene_expression of Trpv1 1 0.09 0.89 0.79
20 INT79339 Phax Regulation of Gene_expression of Tacr1 1 0.07 0 0.78
21 INT50708 Phax Positive_regulation of Trib3 1 0.03 0.07 0.77
22 INT50707 Phax Positive_regulation of Positive_regulation of Trib3 1 0.04 0.16 0.74
23 INT154989 Phax Positive_regulation of Positive_regulation of Ephb1 1 0.22 0.92 0.69
24 INT252869 Binding of Trpv1 and Phax 2 0.01 0.18 0.6
25 INT164265 TGM7 Negative_regulation of CDK2 1 0.26 1.08 0.53
26 INT335851 Snrpc Positive_regulation of Il10 1 0.01 1.17 0.5
27 INT63459 Binding of Calca and Phax 1 0.00 0.12 0.49
28 INT335850 Snrpc Negative_regulation of Gene_expression of Isl1 1 0.00 1.51 0.45
29 INT313704 Smn1 Negative_regulation of Gene_expression of Edn1 1 0.32 0 0.42
30 INT118889 Phax Regulation of Localization of Calca 1 0.05 0.18 0.42
31 INT118890 Phax Positive_regulation of Localization of Calca 1 0.05 0.18 0.42
32 INT151694 Binding of FBL and RNF130 1 0.40 0.23 0.36
33 INT262307 CAPNS1 Regulation of TAF9 1 0.04 1.23 0.33
34 INT225160 Negative_regulation of Binding of CDK2 and CDKN1A 1 0.35 0 0.25
35 INT61707 Phax Positive_regulation of Gene_expression of Gal 1 0.10 0 0.2
36 INT55164 Binding of NFKB1 and WRAP53 1 0.02 0.11 0.19
37 INT337260 ELL Positive_regulation of Gene_expression of THBS1 1 0.11 0.82 0.18
38 INT337263 ELL Regulation of Gene_expression of THBS1 1 0.10 0.82 0.18
39 INT43118 Binding of Pla2g1b and Phax 1 0.03 0 0.15
40 INT295336 Binding of Grb7 and Xpo1 1 0.09 0.31 0.15
41 INT295342 Binding of Hua and Xpo1 1 0.06 0.31 0.15
42 INT123194 Bmp6 Positive_regulation of TAF9 1 0.18 0.61 0.14
43 INT88410 BMP7 Negative_regulation of CDK2 1 0.35 0 0.14
44 INT255808 SMN2 Positive_regulation of SMN1 1 0.41 0.89 0.14
45 INT123193 Bmp6 Positive_regulation of Negative_regulation of TAF9 1 0.18 0.61 0.14
46 INT73923 FBL Positive_regulation of Localization of COL7A1 1 0.36 0.33 0.13
47 INT55163 Binding of RELA and WRAP53 1 0.01 0.05 0.1
48 INT245952 Phax Negative_regulation of TRPV1 1 0.00 0.06 0.1
49 INT165619 Binding of LPL and TGS1 1 0.04 0.61 0.09
50 INT221668 Sema3a Positive_regulation of NPAT 1 0.36 0.47 0.09
51 INT245951 Binding of FIBP and Phax 1 0.00 0 0.09
52 INT88411 Positive_regulation of PDGFA Positive_regulation of CDK2 1 0.11 0 0.07
53 INT258021 Positive_regulation of Binding of CDK2 and CDKN1A 1 0.11 0.84 0.07
54 INT333051 Binding of HIVEP1 and NOLC1 1 0.00 4.11 0.07
55 INT88408 PDGFA Positive_regulation of CDK2 1 0.11 0 0.07
56 INT310727 Binding of DKC1 and TERT 1 0.23 0.91 0.05
57 INT333852 Binding of Ccna1 and Cdk2 1 0.20 0.48 0.04
58 INT213392 Binding of SELPLG and XPO1 1 0.02 0.31 0.04
59 INT248493 Pdss1 Positive_regulation of Gene_expression of Smn1 1 0.16 0.4 0.03
60 INT191182 Binding of IRF1 and PRPF31 1 0.06 0.09 0.03
61 INT289608 Binding of CDK2 and CCNE2 5 0.06 4.89 0
62 INT219412 CDK2 Regulation of PCNA 1 0.20 0.11 0
63 INT303406 Binding of NPAT and Myo1f 1 0.06 0 0
64 INT295338 Ptpn11 Regulation of Binding of Xpo1 1 0.02 0 0
65 INT279905 Binding of SNRNP70 and TGS1 1 0.01 1.85 0
66 INT342600 Proc Positive_regulation of Coil 1 0.00 0.47 0
67 INT279900 Binding of RS1 and TGS1 1 0.00 1.12 0
68 INT295344 Regulation of Binding of Hua and Xpo1 1 0.05 0 0
69 INT306827 Binding of E2F2 and NOLC1 1 0.07 0.05 0
70 INT295408 Binding of Oprk1 and Xpo1 1 0.00 0 0
71 INT325156 CDKN1B Negative_regulation of CDK2 1 0.49 0.11 0
72 INT303405 Binding of NPAT and Jag1 1 0.39 0 0
73 INT303342 Binding of NPAT and TCAP 1 0.40 0 0
74 INT176288 Binding of Cdk2 and Pcna 1 0.01 0.66 0
75 INT213391 Positive_regulation of Binding of CHKB and XPO1 1 0.04 0.46 0
76 INT279894 Binding of USF1 and TGS1 1 0.11 3.52 0
77 INT248491 Binding of Smn1 and Pdss1 1 0.12 0.21 0
78 INT248495 Pdss1 Positive_regulation of Smn1 1 0.13 0.25 0
79 INT219426 CDK2 Regulation of HNF4A 1 0.01 0.11 0
80 INT295410 Positive_regulation of Binding of Oprk1 and Xpo1 1 0.00 0 0
81 INT252900 PTTG1 Regulation of Gene_expression of TAF9 1 0.20 0.84 0
82 INT314688 Binding of CCNE1 and CDK2 1 0.04 1.41 0
83 INT286574 Gene_expression of Pkd1 Negative_regulation of Cdk2 1 0.10 0.09 0
84 INT248496 Smn1 Positive_regulation of Gene_expression of Snrpn 1 0.16 0.09 0
85 INT248499 Smn1 Regulation of Snrpn 1 0.15 0.06 0
86 INT268342 Binding of APC and ANKS1B 1 0.01 0.92 0
87 INT135869 Binding of ICA1 and XPO1 1 0.18 0 0
88 INT219413 CDK2 Regulation of SKP2 1 0.23 0.11 0
89 INT295043 Akt1 Positive_regulation of Cdk2 1 0.10 0.93 0
90 INT248492 Upf1 Positive_regulation of Smn1 1 0.03 0.15 0
91 INT290214 Binding of FRG1 and FSHMD1A 1 0.22 0.98 0
92 INT279909 Binding of FADS3 and TGS1 1 0.12 6 0
93 INT232055 Binding of XPO1 and RNPC3 1 0.02 0.3 0
94 INT232052 Binding of DDR1 and XPO1 1 0.01 0.3 0
95 INT335607 Binding of INS and TGS1 1 0.04 0.95 0
96 INT252893 PTTG1 Positive_regulation of Gene_expression of TAF9 1 0.21 0.9 0
97 INT322544 Binding of CDK2 and Ccne1 1 0.16 0 0
98 INT322503 Negative_regulation of Binding of CDK2 and CCNE2 1 0.01 0.25 0
99 INT333850 Binding of Ccne1 and Cdk2 1 0.26 0 0
100 INT194268 Binding of PLA2G2A and NHP2 1 0.00 0 0
101 INT279910 SNRNP70 Regulation of TGS1 1 0.01 0.76 0
102 INT248500 Positive_regulation of Upf1 Positive_regulation of Smn1 1 0.03 0.15 0
103 INT248498 Smn1 Positive_regulation of Pdss1 1 0.16 0.09 0
104 INT213394 Binding of CHKB and XPO1 1 0.03 0.46 0
105 INT176287 Cdk2 Positive_regulation of Phosphorylation of Esr1 1 0.05 0.67 0
106 INT219419 CDK2 Regulation of E2F2 1 0.23 0.11 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for Cajal body. They are ordered first by their pain relevance and then by number of times they were reported in Cajal body. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT23222 Binding of Phax 52 0.31 7.61 30.4
2 INT22066 Gene_expression of Phax 40 0.78 22.51 25.91
3 INT52775 Positive_regulation of Phax 15 0.42 6.87 11.45
4 INT135088 Negative_regulation of Phax 15 0.36 8.93 8.29
5 INT50705 Localization of Phax 9 0.44 4.65 6.53
6 INT15339 Regulation of Phax 8 0.45 4.34 6.49
7 INT23221 Negative_regulation of Binding of Phax 10 0.37 1.57 5.97
8 INT55710 Positive_regulation of Gene_expression of Phax 5 0.41 1.45 4.16
9 INT135087 Negative_regulation of Gene_expression of Phax 5 0.17 4.39 4.1
10 INT88414 Negative_regulation of CDK2 30 0.57 18.4 3.96
11 INT252968 Positive_regulation of TAF9 11 0.45 5.28 3.68
12 INT107456 Localization of Smn1 2 0.46 1.18 3.1
13 INT252999 Gene_expression of TAF9 12 0.75 12.65 2.92
14 INT281645 Regulation of Gene_expression of Phax 3 0.08 2.51 2.44
15 INT9119 Negative_regulation of TAF9 4 0.42 5.21 2.16
16 INT262317 Binding of TAF9 7 0.31 9.67 2.15
17 INT335846 Localization of Snrpc 1 0.02 6.77 1.97
18 INT73927 Gene_expression of FBL 10 0.48 3.55 1.72
19 INT88412 Positive_regulation of CDK2 17 0.57 8.49 1.66
20 INT123303 Gene_expression of Smn1 40 0.71 15.5 1.18
21 INT107457 Positive_regulation of Smn1 3 0.30 1.26 1.13
22 INT49556 Gene_expression of NOLC1 11 0.49 29.44 1.07
23 INT106735 Phosphorylation of CDK2 11 0.79 4.03 1.02
24 INT38625 Gene_expression of ELL 8 0.58 12.53 1
25 INT163176 Regulation of Localization of Phax 1 0.24 0 0.96
26 INT205497 Binding of NOLC1 13 0.35 15.91 0.91
27 INT283927 Negative_regulation of Positive_regulation of Phax 2 0.12 1.43 0.91
28 INT135086 Phosphorylation of Phax 1 0.32 1.55 0.87
29 INT135085 Negative_regulation of Phosphorylation of Phax 1 0.17 1.56 0.87
30 INT8159 Binding of ELL 7 0.36 12.62 0.84
31 INT73464 Gene_expression of SART1 1 0.02 0.79 0.81
32 INT114880 Negative_regulation of Cdk2 7 0.35 3.89 0.77
33 INT165621 Negative_regulation of TGS1 4 0.14 4.5 0.72
34 INT283660 Regulation of Positive_regulation of Phax 1 0.03 1.49 0.71
35 INT313696 Negative_regulation of Smn1 1 0.25 0.22 0.69
36 INT105330 Gene_expression of CDK2 31 0.63 13.7 0.67
37 INT75453 Gene_expression of SMN2 4 0.75 2.55 0.67
38 INT159519 Positive_regulation of Smn1 2 0.64 4.96 0.64
39 INT114879 Gene_expression of Cdk2 5 0.55 2.33 0.6
40 INT114872 Negative_regulation of Gene_expression of Cdk2 2 0.35 1.21 0.6
41 INT113846 Negative_regulation of Positive_regulation of CDK2 1 0.48 0.39 0.6
42 INT151697 Binding of FBL 2 0.36 2.06 0.59
43 INT143398 Regulation of ELL 2 0.44 2.17 0.59
44 INT306880 Localization of NOLC1 2 0.19 6.32 0.54
45 INT323004 Transcription of TAF9 1 0.05 0.79 0.54
46 INT123305 Positive_regulation of Gene_expression of Smn1 2 0.55 2.55 0.53
47 INT212596 Positive_regulation of NOLC1 3 0.37 4.7 0.51
48 INT163285 Negative_regulation of Phosphorylation of CDK2 2 0.32 0.52 0.48
49 INT322997 Localization of TAF9 1 0.05 1.2 0.4
50 INT75454 Negative_regulation of Gene_expression of SMN2 1 0.08 0.52 0.39
51 INT49557 Transcription of NOLC1 4 0.02 16.54 0.38
52 INT310728 Binding of DKC1 1 0.25 2.36 0.38
53 INT238902 Binding of TGS1 3 0.07 2.86 0.36
54 INT151695 Positive_regulation of FBL 2 0.49 0.65 0.36
55 INT194274 Positive_regulation of NHP2 3 0.05 0.09 0.33
56 INT252969 Positive_regulation of Gene_expression of TAF9 5 0.67 5.22 0.32
57 INT73925 Regulation of FBL 3 0.22 2.19 0.31
58 INT43117 Protein_catabolism of Phax 2 0.38 0.14 0.27
59 INT248468 Negative_regulation of Smn1 6 0.39 5.55 0.25
60 INT248477 Regulation of Gene_expression of Smn1 1 0.41 2.17 0.25
61 INT106733 Regulation of CDK2 6 0.44 4.76 0.23
62 INT83974 Transcription of Coil 1 0.35 1.26 0.23
63 INT221610 Gene_expression of NPAT 1 0.65 0.18 0.19
64 INT301343 Negative_regulation of Positive_regulation of ELL 1 0.08 1.64 0.17
65 INT163284 Negative_regulation of Gene_expression of CDK2 5 0.32 1.6 0.16
66 INT238096 Positive_regulation of ELL 4 0.09 2.68 0.16
67 INT176246 Regulation of Cdk2 6 0.30 3.31 0.15
68 INT130004 Positive_regulation of Protein_catabolism of FRG1 1 0.01 1.16 0.15
69 INT130003 Protein_catabolism of FRG1 1 0.03 1.16 0.15
70 INT248488 Transcription of Smn1 1 0.55 0.64 0.14
71 INT165623 Gene_expression of TGS1 5 0.22 3.42 0.13
72 INT165622 Negative_regulation of Gene_expression of TGS1 2 0.14 1.54 0.13
73 INT201462 Binding of CDK2 12 0.39 5.2 0.12
74 INT280011 Negative_regulation of NOLC1 3 0.31 3.31 0.12
75 INT280017 Regulation of NOLC1 2 0.33 2.31 0.1
76 INT201460 Positive_regulation of Gene_expression of CDK2 5 0.52 2.8 0.09
77 INT169428 Regulation of Gene_expression of CDK2 4 0.46 1.03 0.09
78 INT106732 Regulation of Phosphorylation of CDK2 2 0.44 0.8 0.09
79 INT302272 Localization of CDK2 2 0.30 1.09 0.09
80 INT194272 Positive_regulation of Gene_expression of NHP2 1 0.03 0.19 0.09
81 INT194270 Gene_expression of NHP2 1 0.04 0.09 0.09
82 INT213406 Positive_regulation of XPO1 5 0.27 1.19 0.08
83 INT252991 Regulation of TAF9 2 0.44 3.54 0.08
84 INT328553 Positive_regulation of Gene_expression of SMN2 1 0.49 1.03 0.07
85 INT295383 Localization of Xpo1 1 0.16 0.14 0.07
86 INT306852 Positive_regulation of Phosphorylation of NOLC1 1 0.13 0.13 0.05
87 INT213405 Regulation of XPO1 1 0.17 0.87 0.05
88 INT194271 Positive_regulation of Positive_regulation of NHP2 1 0.03 0.09 0.05
89 INT306877 Phosphorylation of NOLC1 1 0.21 0.13 0.05
90 INT212930 Localization of ELL 2 0.15 0.87 0.04
91 INT282568 Positive_regulation of Cdk2 6 0.34 2.95 0.03
92 INT193612 Transcription of SART1 2 0.58 1.56 0.03
93 INT201468 Negative_regulation of Binding of CDK2 2 0.17 1.1 0.03
94 INT194273 Regulation of NHP2 1 0.03 0.24 0.03
95 INT333082 Regulation of Gene_expression of NOLC1 1 0.01 2.09 0.03
96 INT230372 Negative_regulation of ELL 5 0.03 1.35 0
97 INT169427 Transcription of CDK2 2 0.09 0.42 0
98 INT279931 Positive_regulation of TGS1 2 0.13 3.04 0
99 INT124651 Gene_expression of XPO1 2 0.30 0.64 0
100 INT242456 Binding of Cdk2 2 0.16 1.29 0
101 INT295036 Positive_regulation of Positive_regulation of Cdk2 2 0.34 0.93 0
102 INT236705 Phosphorylation of Cdk2 2 0.31 1.39 0
103 INT248482 Localization of Smn1 1 0.69 0.5 0
104 INT333070 Protein_catabolism of NOLC1 1 0.03 2.65 0
105 INT285901 Regulation of Transcription of CDK2 1 0.03 0.7 0
106 INT192280 Binding of PRPF31 1 0.36 0.25 0
107 INT295394 Regulation of Xpo1 1 0.10 0 0
108 INT295035 Negative_regulation of Positive_regulation of Cdk2 1 0.22 0.87 0
109 INT248478 Negative_regulation of Gene_expression of Smn1 1 0.39 0.14 0
110 INT279929 Positive_regulation of Positive_regulation of TGS1 1 0.10 1.36 0
111 INT169913 Positive_regulation of Gene_expression of Cdk2 1 0.21 0.08 0
112 INT277859 Protein_catabolism of Cdk2 1 0.43 0.23 0
113 INT308071 Gene_expression of ANKS1B 1 0.03 1.04 0
114 INT186225 Regulation of NPAT 1 0.05 0 0
115 INT333793 Transcription of Cdk2 1 0.46 0 0
116 INT248479 Positive_regulation of Positive_regulation of Smn1 1 0.46 0.08 0
117 INT341855 Positive_regulation of Positive_regulation of CDK2 1 0.06 0.51 0
118 INT279935 Localization of TGS1 1 0.15 0.8 0
119 INT194275 Binding of NHP2 1 0.02 0 0
120 INT352993 Positive_regulation of SMN2 1 0.28 0.4 0
121 INT333816 Regulation of Positive_regulation of Cdk2 1 0.30 0 0
122 INT290242 Localization of FRG1 1 0.68 0.56 0
123 INT289620 Regulation of Binding of CDK2 1 0.28 0.22 0
124 INT295381 Binding of Xpo1 1 0.08 0 0
125 INT248474 Negative_regulation of Positive_regulation of Smn1 1 0.34 0 0
126 INT295384 Phosphorylation of Xpo1 1 0.14 0 0
127 INT290237 Negative_regulation of Localization of FRG1 1 0.39 0.58 0
128 INT248469 Binding of Smn1 1 0.34 0.52 0
129 INT302873 Regulation of DKC1 1 0.37 0.05 0
130 INT248480 Regulation of Smn1 1 0.41 0.38 0
131 INT290267 Gene_expression of FRG1 1 0.71 2.63 0
132 INT290258 Binding of FRG1 1 0.36 0.3 0
133 INT213396 Regulation of Gene_expression of XPO1 1 0.15 0 0
134 INT325169 Regulation of Negative_regulation of CDK2 1 0.34 0.05 0
135 INT290248 Positive_regulation of Gene_expression of FRG1 1 0.46 1.14 0
136 INT333817 Localization of Cdk2 1 0.50 0.22 0
137 INT225187 Positive_regulation of Binding of CDK2 1 0.56 0.87 0
138 INT252984 Regulation of Gene_expression of TAF9 1 0.26 0.99 0
139 INT202676 Negative_regulation of NPAT 1 0.41 0 0
140 INT338717 Gene_expression of DKC1 1 0.01 0.41 0
141 INT193611 Negative_regulation of SART1 1 0.41 0.68 0
142 INT182412 Localization of FBL 1 0.14 0.05 0
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