GO:0016071

Name mRNA metabolic process Categary Process Go Slim No Go Link GO:0016071

Unique Molecular Interactions 427 Total Molecular Interactions 517 Total Single Events 3690 Pain Genes Associated 59

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for mRNA metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for mRNA metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT135516	PRKCA Negative_regulation of Phosphorylation of OPRM1	1	0.12	0	1.62
2	INT118515	Positive_regulation of PRKCA Positive_regulation of Phosphorylation of TRPV1	1	0.27	0.56	1.58
3	INT166676	Binding of PRKCA and UGT1A6	1	0.30	0	1.5
4	INT51388	Binding of CSF2 and RPLP0	1	0.11	1.8	1.27
5	INT139724	PROC Positive_regulation of MAPK14	1	0.00	1.57	1.25
6	INT330379	Gene_expression of IL10 Negative_regulation of Positive_regulation of MAPK14	1	0.00	1.95	1.18
7	INT225067	Binding of ETF1 and IGHG3	1	0.03	4.52	1.17
8	INT182159	Binding of HGF and DCPS	1	0.01	2.5	1.17
9	INT323175	PRKCA Positive_regulation of Akt1	1	0.02	0	1.1
10	INT108547	AKT1 Regulation of MAPKAPK5	1	0.04	1.2	1.08
11	INT79602	Binding of PSMA5 and Oprd1	2	0.19	1.05	1.01
12	INT69506	CA2 Positive_regulation of PRKCA	1	0.50	0.42	0.98
13	INT72213	Positive_regulation of PRKCA Regulation of Gene_expression of METTL3	1	0.05	0.17	0.93
14	INT209928	IL1B Positive_regulation of MAPK14	2	0.15	1.69	0.87
15	INT116106	VEGFA Positive_regulation of AKT1	1	0.12	0.3	0.83
16	INT189671	DAG1 Positive_regulation of PRKCA	3	0.12	0.71	0.82
17	INT144286	ACP1 Negative_regulation of Phosphorylation of PSMC6	1	0.45	0.39	0.78
18	INT346234	MAP2K6 Positive_regulation of MAPK14	1	0.44	1.65	0.77
19	INT166674	YY1 Regulation of Binding of PRKCA	1	0.38	0	0.75
20	INT315185	Binding of CNOT1 and Tg(CAG-EGFP)D4Nagy	1	0.04	0.16	0.74
21	INT251729	Binding of FEN1 and EXOSC1	1	0.19	1.13	0.74
22	INT142994	Binding of UPF1 and FCMTE1	1	0.00	0.91	0.7
23	INT166673	PRKCA Negative_regulation of UGT1A6	1	0.36	0	0.69
24	INT299989	PRKCA Positive_regulation of Gene_expression of IL8	1	0.04	0.45	0.67
25	INT189704	PRKCA Regulation of CHKB	1	0.13	0.18	0.66
26	INT169293	PTPLA Positive_regulation of AKT1	1	0.10	0.15	0.64
27	INT337323	KNG1 Positive_regulation of PRKCA	1	0.15	0.17	0.62
28	INT278695	MTX1 Negative_regulation of Phosphorylation of AKT1	1	0.04	0.81	0.62
29	INT81606	Positive_regulation of PRKCA Positive_regulation of Phosphorylation of TACR1	1	0.29	0	0.6
30	INT225065	Binding of ETF1 and FANCB	1	0.01	2.07	0.59
31	INT81605	PRKCA Positive_regulation of Phosphorylation of TACR1	1	0.43	0	0.57
32	INT225083	Binding of ETF1 and fc	1	0.00	2.13	0.57
33	INT323176	PRKCA Positive_regulation of Phosphorylation of Akt1	1	0.02	0	0.56
34	INT278694	TNF Positive_regulation of MAPK14	1	0.03	0.79	0.56
35	INT323148	PRKCA Positive_regulation of RAF1	1	0.01	0	0.55
36	INT201944	CXCL10 Positive_regulation of Phosphorylation of AKT1	1	0.09	0.79	0.55
37	INT323150	PRKCA Positive_regulation of Phosphorylation of RAF1	1	0.01	0	0.55
38	INT339532	FGF2 Positive_regulation of YWHAZ	1	0.00	1.26	0.54
39	INT323146	PRKCA Positive_regulation of MAPK1	1	0.02	0	0.54
40	INT310701	RPLP0 Regulation of Positive_regulation of PGR	1	0.01	0.49	0.53
41	INT143862	Bdnf Positive_regulation of Gene_expression of NUP214	1	0.27	0.61	0.52
42	INT171906	MAPK1 Positive_regulation of Gene_expression of MAPK14	1	0.08	1.55	0.52
43	INT143861	Nfatc1 Regulation of Gene_expression of NUP214	1	0.00	0.61	0.52
44	INT120383	PRKCD Positive_regulation of Localization of EPHB2	1	0.29	0.42	0.52
45	INT97952	Negative_regulation of NRP2 Negative_regulation of Positive_regulation of AKT1	1	0.03	0.72	0.51
46	INT120384	PRKCD Positive_regulation of Localization of HSPG2	1	0.29	0.42	0.51
47	INT120382	PRKCD Positive_regulation of Localization of DYT10	1	0.29	0.42	0.51
48	INT189688	PRKCA Regulation of Transcription of TERT	1	0.13	0.2	0.5
49	INT189696	PRKCA Negative_regulation of Negative_regulation of TEP1	1	0.02	0.15	0.5
50	INT189680	PRKCA Negative_regulation of TEP1	1	0.02	0.15	0.5
51	INT97951	ST3GAL3 Positive_regulation of AKT1	1	0.04	0.7	0.5
52	INT189675	Negative_regulation of PRKCA Negative_regulation of TEP1	1	0.02	0.15	0.5
53	INT102599	Binding of EXOSC3 and TPPP3	3	0.39	2.61	0.48
54	INT182150	Binding of APC and DCPS	1	0.02	1.14	0.48
55	INT261648	BDKRB1 Regulation of PRKCA	1	0.03	1.9	0.47
56	INT162932	TXNRD1 Negative_regulation of Phosphorylation of AKT1	1	0.14	1.01	0.47
57	INT142826	UPF1 Positive_regulation of CREB1	1	0.11	0	0.46
58	INT153658	PRKCA Negative_regulation of GEM	1	0.01	0.22	0.46
59	INT233668	Cebpd Negative_regulation of Cebpg	1	0.43	0.66	0.46
60	INT153657	PRKCA Negative_regulation of MED23	1	0.01	0.22	0.46
61	INT162929	NQO1 Negative_regulation of Phosphorylation of AKT1	1	0.41	1	0.46
62	INT110475	EDN1 Regulation of PRKCA	1	0.05	0.07	0.45
63	INT310711	Binding of RPLP0 and Gabrg1	1	0.04	0.37	0.45
64	INT278964	MAPK14 Negative_regulation of Localization of EPHB2	1	0.15	0.47	0.43
65	INT160047	PTEN Regulation of Gene_expression of AKT1	1	0.33	0.6	0.42
66	INT160048	INPPL1 Regulation of Gene_expression of AKT1	1	0.28	0.6	0.42
67	INT121851	AKT1 Regulation of ROS1	1	0.16	0.52	0.41
68	INT121848	AKT1 Regulation of CASP8	1	0.18	0.52	0.41
69	INT13879	Binding of PSMB9 and KCNAB2	1	0.03	0.19	0.41
70	INT189681	Negative_regulation of PRKCA Negative_regulation of Gene_expression of METTL3	1	0.00	0.16	0.41
71	INT121854	AKT1 Regulation of BID	1	0.17	0.52	0.41
72	INT187487	Cebpg Positive_regulation of Gene_expression of Nos2	1	0.03	0.38	0.4
73	INT108197	AKT1 Regulation of JUN	1	0.29	0.25	0.4
74	INT189689	CHKB Negative_regulation of Positive_regulation of PRKCA	1	0.11	0	0.4
75	INT124799	PRKCA Positive_regulation of Localization of ADCY6	1	0.19	0	0.4
76	INT121853	Gene_expression of ROS1 Negative_regulation of AKT1	1	0.25	0.49	0.4
77	INT182158	Binding of IL3RA and DCPS	1	0.06	0.77	0.39
78	INT124798	RAF1 Regulation of PRKCA	1	0.06	0	0.39
79	INT278970	MAPK14 Positive_regulation of Gene_expression of IL8	1	0.11	0.66	0.37
80	INT278955	JAK3 Positive_regulation of Gene_expression of PRKCA	1	0.12	0.65	0.37
81	INT193034	PRKCA Regulation of Positive_regulation of CDK20	1	0.05	0.15	0.37
82	INT278938	MAPK14 Positive_regulation of Gene_expression of PRKCA	1	0.05	0.65	0.37
83	INT89386	INS Positive_regulation of Phosphorylation of AKT1	3	0.43	1.48	0.36
84	INT299288	AKT1 Positive_regulation of RPTOR	1	0.34	0.05	0.36
85	INT329170	DCPS Positive_regulation of Gene_expression of IFN1@	1	0.04	1.55	0.36
86	INT278966	MAPK14 Positive_regulation of Gene_expression of LEP	1	0.16	0.62	0.36
87	INT268110	PRKCA Positive_regulation of Phosphorylation of SNAP25	1	0.32	0.11	0.35
88	INT176135	AKT1 Regulation of Localization of CYCS	1	0.43	2.16	0.35
89	INT346228	MAP2K6 Positive_regulation of Positive_regulation of MAPK14	1	0.44	0.68	0.34
90	INT193784	ITIH4 Positive_regulation of YWHAZ	1	0.04	1.21	0.34
91	INT346229	PREP Positive_regulation of MAPK14	1	0.13	0.63	0.34
92	INT89381	INS Positive_regulation of AKT1	6	0.43	3.06	0.33
93	INT346236	Binding of MAPK14 and MAP2K6	1	0.32	0.65	0.33
94	INT171679	PPY Regulation of PRKCA	1	0.08	0.33	0.33
95	INT175552	Binding of CASR and UPF1	1	0.01	0.89	0.33
96	INT346231	Binding of MAPK14 and MAP2K3	1	0.33	0.65	0.33
97	INT297972	MAPK14 Negative_regulation of ING5	1	0.21	1.67	0.33
98	INT171677	PRKCA Regulation of CISD1	1	0.00	0	0.33
99	INT255944	MAPK14 Positive_regulation of Tauph	1	0.00	0.1	0.32
100	INT259639	MAPK14 Regulation of Gene_expression of IL8	1	0.02	1.2	0.32
101	INT255945	MAPK14 Positive_regulation of Rps6ka5	1	0.06	0.1	0.32
102	INT255946	MAPK14 Positive_regulation of Map3k1	1	0.04	0.1	0.32
103	INT337410	AKT3 Negative_regulation of AKT1	1	0.09	0.49	0.32
104	INT337414	AKT2 Negative_regulation of AKT1	1	0.10	0.5	0.32
105	INT346235	IL1B Positive_regulation of Gene_expression of MAPK14	1	0.15	0.64	0.32
106	INT299307	AKT1 Positive_regulation of Positive_regulation of AKT1S1	1	0.10	0	0.3
107	INT299289	AKT1 Positive_regulation of Positive_regulation of TSC2	1	0.17	0	0.3
108	INT101562	Binding of TNPO1 and Oprl1	1	0.00	0.12	0.3
109	INT112799	Positive_regulation of CASP1 Positive_regulation of MAPK14	1	0.02	0.16	0.3
110	INT303995	Lep Positive_regulation of PSME1	1	0.09	0.32	0.29
111	INT291202	Positive_regulation of INS Positive_regulation of AKT1	1	0.01	0.76	0.29
112	INT123663	F2R Positive_regulation of MAPK14	1	0.12	0.42	0.26
113	INT123662	Negative_regulation of F2R Positive_regulation of MAPK14	1	0.08	0.42	0.26
114	INT171907	MAPK8 Positive_regulation of Gene_expression of MAPK14	1	0.06	0.77	0.26
115	INT156156	Positive_regulation of Binding of NGF and SMG1	1	0.03	0.41	0.26
116	INT123661	COL7A1 Positive_regulation of MAPK14	1	0.08	0.42	0.26
117	INT171911	MAPK8IP3 Positive_regulation of Gene_expression of MAPK14	1	0.05	0.77	0.26
118	INT355982	Binding of HLA-DQA2 and DCPS	1	0.00	1.33	0.26
119	INT310700	PGR Regulation of Gene_expression of RPLP0	1	0.01	0.37	0.25
120	INT35178	Binding of STT3A and PSME3	1	0.01	0.38	0.25
121	INT355983	CSF2 Regulation of Gene_expression of DCPS	1	0.02	0.84	0.25
122	INT189692	INSRR Positive_regulation of PRKCA	1	0.00	0	0.24
123	INT189693	CHKB Positive_regulation of PRKCA	1	0.11	0	0.24
124	INT189700	CHKB Negative_regulation of PRKCA	1	0.11	0	0.24
125	INT118858	PRKCA Regulation of Phosphorylation of SRC	1	0.10	0.15	0.24
126	INT156157	Binding of NGF and SMG1	1	0.02	0.4	0.23
127	INT179230	Binding of MAPK14 and GSR	1	0.03	0.5	0.23
128	INT335462	IGHE Regulation of Positive_regulation of PRKCA	1	0.07	0	0.23
129	INT355985	IDO1 Positive_regulation of Gene_expression of DCPS	1	0.02	1.21	0.23
130	INT265886	IGF1 Positive_regulation of AKT1	1	0.11	3.06	0.23
131	INT112794	CASP1 Positive_regulation of MAPK14	1	0.02	0.16	0.23
132	INT341779	DBT Positive_regulation of PRKCA	1	0.02	0	0.22
133	INT112793	IL4I1 Positive_regulation of Positive_regulation of MAPK14	1	0.04	0	0.22
134	INT335464	Binding of DAG1 and PRKCA	1	0.03	0	0.22
135	INT173357	Gnaq Positive_regulation of PRKCA	1	0.01	0	0.22
136	INT297965	MAPK14 Negative_regulation of GADD45A	1	0.05	1	0.21
137	INT337168	DCPS Negative_regulation of CD86	1	0.02	1.54	0.21
138	INT120716	Binding of AKT1 and TEP1	1	0.05	0.46	0.21
139	INT221955	Binding of ELAVL1 and CDK5R1	1	0.01	0.93	0.19
140	INT106630	Binding of GRK5 and PRKCA	1	0.16	0.82	0.19
141	INT225649	IL4 Positive_regulation of Localization of DCPS	1	0.02	1.03	0.19
142	INT182152	DCPS Positive_regulation of IFNA1	1	0.02	0.45	0.18
143	INT193081	PRKCA Positive_regulation of Ppp1r14a	1	0.01	0.13	0.18
144	INT182149	DCPS Positive_regulation of Binding of IFNA1	1	0.02	0.45	0.18
145	INT298192	EGFR Positive_regulation of AKT1	1	0.10	0.65	0.18
146	INT121582	AKT1 Regulation of Gene_expression of GDF15	1	0.21	0.4	0.18
147	INT318680	Binding of Cebpg and Ddit3	1	0.39	1.73	0.18
148	INT318324	Binding of AKT1 and PRKCA	1	0.03	0.63	0.18
149	INT182155	DCPS Positive_regulation of Positive_regulation of ITGAX	1	0.04	0.46	0.18
150	INT176133	AKT1 Regulation of BCL2	2	0.12	1.84	0.17
151	INT194696	TTPA Positive_regulation of Phosphorylation of MAPKAPK2	1	0.01	0.08	0.17
152	INT105334	PTGER1 Positive_regulation of Positive_regulation of AKT1	1	0.05	0.66	0.17
153	INT176134	AKT1 Regulation of Gene_expression of BIRC3	1	0.08	1.09	0.17
154	INT97889	Binding of RQCD1 and NPS	1	0.13	1.69	0.17
155	INT194737	Binding of TTPA and MAPKAPK2	1	0.01	0.08	0.17
156	INT180503	Binding of SARS and PSMD6	1	0.22	2.44	0.16
157	INT178079	EDN1 Positive_regulation of Positive_regulation of AKT1	1	0.05	0.91	0.16
158	INT226518	Il1rl1 Positive_regulation of MAPK14	1	0.04	0.2	0.15
159	INT269330	DYNC1I2 Negative_regulation of PRKCA	1	0.03	0	0.15
160	INT226520	Il1rl1 Positive_regulation of Gene_expression of MAPK14	1	0.03	0.2	0.15
161	INT249829	CHI3L1 Positive_regulation of AKT1	1	0.47	0.69	0.14
162	INT344710	Lipc Positive_regulation of Positive_regulation of Hdl1	1	0.04	0.87	0.14
163	INT298639	GDE1 Negative_regulation of AKT1	1	0.00	1.14	0.14
164	INT269326	PRKCA Positive_regulation of Localization of TMPO	1	0.01	0	0.13
165	INT269336	PRKCA Regulation of Localization of TMPO	1	0.01	0.12	0.13
166	INT302156	AKT1 Positive_regulation of E2F2	1	0.02	0.88	0.13
167	INT295480	MAPK14 Positive_regulation of Localization of TNF	1	0.08	1.08	0.12
168	INT341239	Binding of EIF4E and Eif4e	1	0.08	0.23	0.12
169	INT341238	Binding of EIF4E and Eif4g3	1	0.03	0.23	0.12
170	INT299310	RPTOR Positive_regulation of AKT1	1	0.30	0	0.12
171	INT269335	PRKG1 Positive_regulation of Gene_expression of PRKCA	1	0.14	0	0.12
172	INT287881	THEMIS Positive_regulation of PRKCA	1	0.00	0.07	0.12
173	INT297967	MAPK14 Negative_regulation of SCUBE3	1	0.01	0.67	0.12
174	INT182154	Binding of HLA-DRA and DCPS	1	0.01	0.23	0.12
175	INT105338	Prkaca Positive_regulation of AKT1	1	0.04	0.93	0.11
176	INT291260	Map3k8 Regulation of Gene_expression of MAPK14	1	0.07	0.52	0.11
177	INT302161	AKT1 Negative_regulation of CASP9	1	0.03	0.87	0.11
178	INT176130	AKT1 Regulation of Gene_expression of COX18	1	0.13	0.82	0.11
179	INT118587	Binding of UPF1 and CLEC4F	1	0.00	0.22	0.1
180	INT194671	MAPKAPK2 Positive_regulation of CREB1	1	0.06	0.05	0.1
181	INT194689	MAPKAPK2 Positive_regulation of TFAM	1	0.00	0.05	0.1
182	INT213421	Binding of CXCL2 and SET	1	0.11	0.17	0.1
183	INT213417	Binding of CCL7 and SET	1	0.11	0.17	0.1
184	INT343858	Binding of AKT1 and MYD88	1	0.02	0.26	0.1
185	INT57014	PSMB1 Regulation of SCN5A	1	0.02	0	0.1
186	INT213414	Binding of CXCL1 and SET	1	0.10	0.17	0.1
187	INT213415	Binding of CCL8 and SET	1	0.11	0.17	0.1
188	INT213420	Binding of IL6 and SET	1	0.10	0.17	0.1
189	INT213416	Binding of CCL2 and SET	1	0.11	0.17	0.1
190	INT44591	PLAT Negative_regulation of CNOT4	1	0.10	0.33	0.1
191	INT111866	Binding of LNPEP and CNOT4	1	0.02	0	0.09
192	INT287886	Negative_regulation of THEMIS Negative_regulation of PRKCA	1	0.00	1.19	0.08
193	INT298351	PSMD1 Regulation of Gene_expression of HLA-DRA	1	0.01	0.42	0.08
194	INT103810	Binding of PTPRC and RPL26	1	0.09	1.01	0.08
195	INT298356	PSMD1 Regulation of Gene_expression of Cd14	1	0.04	0.42	0.08
196	INT310113	Binding of SET and TP53INP2	1	0.15	0.05	0.08
197	INT264188	DCPS Positive_regulation of Gene_expression of IL10	1	0.02	0.59	0.08
198	INT166784	Binding of PSMD1 and Nkx6-2	1	0.21	0.5	0.08
199	INT269334	Regulation of PRKCA Regulation of ZAK	1	0.02	0	0.07
200	INT269328	PRKCA Regulation of ZAK	1	0.02	0	0.07

Single Events

The table below shows the top 100 pain related interactions that have been reported for mRNA metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in mRNA metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT48718	Positive_regulation of PRKCA	109	0.69	36.16	46.49
2	INT52712	Negative_regulation of PRKCA	64	0.57	23.11	28.43
3	INT86534	Positive_regulation of MAPK14	81	0.62	57.81	23.62
4	INT69322	Negative_regulation of MAPK14	70	0.54	42.92	22.71
5	INT171924	Gene_expression of MAPK14	60	0.65	54.38	21.68
6	INT79805	Phosphorylation of PRKCA	57	0.81	23.33	20.41
7	INT89396	Phosphorylation of AKT1	225	0.82	111.66	19.61
8	INT86187	Positive_regulation of AKT1	199	0.69	122.13	19.44
9	INT69592	Positive_regulation of PSMD1	27	0.70	17.83	18.98
10	INT151747	Positive_regulation of PSMD2	26	0.68	17.48	17.89
11	INT45142	Gene_expression of DCPS	109	0.56	84.71	16.87
12	INT97245	Gene_expression of AKT1	217	0.77	119.63	15.59
13	INT61172	Gene_expression of PRKCA	34	0.77	8.89	15.47
14	INT52714	Regulation of PRKCA	28	0.61	7.73	13.66
15	INT89395	Negative_regulation of AKT1	127	0.58	70.27	12.54
16	INT72221	Localization of PRKCA	17	0.81	1.23	11.47
17	INT110178	Phosphorylation of MAPK14	40	0.68	19.38	10.37
18	INT159631	Positive_regulation of DCPS	60	0.27	43.23	10.3
19	INT73223	Gene_expression of UPF1	78	0.41	31.44	9.94
20	INT75526	Positive_regulation of Positive_regulation of PRKCA	16	0.50	4.34	7.46
21	INT159632	Localization of DCPS	24	0.21	18.24	6.8
22	INT72222	Positive_regulation of Localization of PRKCA	8	0.70	0.55	6.56
23	INT141151	Regulation of PSMD1	16	0.40	8.19	5.86
24	INT154303	Negative_regulation of DCPS	27	0.36	33.83	5.45
25	INT151748	Positive_regulation of Positive_regulation of PSMD2	4	0.49	4.45	5.35
26	INT70800	Negative_regulation of Positive_regulation of PRKCA	9	0.34	2.18	5.17
27	INT105336	Regulation of AKT1	52	0.56	32.53	4.89
28	INT17110	Gene_expression of PSMD1	60	0.65	19.57	4.69
29	INT166678	Negative_regulation of Phosphorylation of PRKCA	12	0.38	5.77	4.59
30	INT124136	Positive_regulation of YWHAZ	7	0.67	1.85	4.51
31	INT117920	Regulation of MAPK14	14	0.38	8.75	4.31
32	INT109450	Positive_regulation of Phosphorylation of AKT1	62	0.64	25.18	4.21
33	INT117921	Positive_regulation of Positive_regulation of MAPK14	9	0.44	9.93	4.18
34	INT69591	Positive_regulation of Positive_regulation of PSMD1	2	0.50	3.06	3.99
35	INT143494	Binding of DCPS	24	0.29	24.41	3.67
36	INT167478	Positive_regulation of Gene_expression of DCPS	23	0.27	14.75	3.37
37	INT69593	Negative_regulation of PSMD1	11	0.57	4.06	3.33
38	INT72216	Regulation of Positive_regulation of PRKCA	9	0.37	1.36	3.26
39	INT108203	Negative_regulation of Gene_expression of AKT1	28	0.54	16.38	3.19
40	INT53495	Negative_regulation of Negative_regulation of PRKCA	4	0.42	2.37	3.18
41	INT89392	Negative_regulation of Positive_regulation of AKT1	23	0.50	15.69	3.02
42	INT173179	Binding of MAPK14	13	0.29	4.51	2.92
43	INT51993	Gene_expression of PSMA5	5	0.75	2.59	2.92
44	INT140547	Negative_regulation of PSMB10	3	0.02	2.33	2.92
45	INT89401	Negative_regulation of Phosphorylation of AKT1	68	0.58	35.61	2.8
46	INT24443	Gene_expression of PSMD2	20	0.54	7.29	2.77
47	INT171682	Positive_regulation of Phosphorylation of PRKCA	3	0.43	1.04	2.72
48	INT200963	Regulation of UPF1	10	0.01	2.18	2.67
49	INT60440	Localization of PSMD1	10	0.74	3.94	2.57
50	INT110179	Negative_regulation of Phosphorylation of MAPK14	11	0.36	5.25	2.38
51	INT106616	Gene_expression of PSMB9	35	0.72	28.4	2.29
52	INT118791	Binding of AKT1	32	0.48	15.51	2.25
53	INT156694	Binding of SET	10	0.36	3.77	2.21
54	INT124138	Gene_expression of YWHAZ	9	0.62	4.04	2.21
55	INT101866	Positive_regulation of Gene_expression of AKT1	49	0.52	17.47	2.14
56	INT120650	Negative_regulation of UPF1	14	0.02	6.86	2.14
57	INT173647	Positive_regulation of Gene_expression of MAPK14	15	0.39	7.54	2.05
58	INT106636	Binding of PRKCA	7	0.28	3.06	1.93
59	INT69027	Binding of PSMA5	4	0.47	1.08	1.93
60	INT148702	Positive_regulation of UPF1	29	0.31	12.9	1.91
61	INT67862	Negative_regulation of ETF1	3	0.29	1.45	1.91
62	INT198568	Regulation of DCPS	17	0.34	16.26	1.86
63	INT123130	Positive_regulation of Positive_regulation of AKT1	22	0.49	11.77	1.83
64	INT81924	Positive_regulation of HSPA1B	1	0.03	1.47	1.82
65	INT79569	Protein_catabolism of PRKCA	3	1.00	0.44	1.78
66	INT148721	Binding of PSMD1	13	0.31	4.78	1.76
67	INT127145	Gene_expression of SET	46	0.65	10.39	1.7
68	INT97571	Positive_regulation of Gene_expression of PRKCA	13	0.43	1.61	1.7
69	INT124137	Positive_regulation of Positive_regulation of YWHAZ	1	0.67	0	1.7
70	INT173173	Regulation of Positive_regulation of MAPK14	6	0.38	2.59	1.64
71	INT159185	Positive_regulation of Gene_expression of PSMD2	3	0.40	1.4	1.63
72	INT17885	Negative_regulation of YWHAZ	6	0.56	2.74	1.58
73	INT164152	Negative_regulation of PSMD2	9	0.37	3.41	1.56
74	INT182297	Positive_regulation of Phosphorylation of MAPK14	7	0.42	3.36	1.53
75	INT173654	Localization of MAPK14	12	0.62	3.16	1.43
76	INT69513	Regulation of PSMA5	2	0.60	1.04	1.43
77	INT108587	Negative_regulation of PSMA5	1	0.57	1.73	1.42
78	INT52713	Regulation of Negative_regulation of PRKCA	5	0.36	1.23	1.41
79	INT6018	Positive_regulation of PSMB9	7	0.60	4.36	1.33
80	INT200979	Regulation of Gene_expression of UPF1	4	0.28	2.19	1.31
81	INT159360	Positive_regulation of SMG1	11	0.67	2.01	1.29
82	INT79660	Phosphorylation of PSMC6	3	0.80	0.45	1.28
83	INT67254	Gene_expression of RPLP0	6	0.38	2.7	1.24
84	INT77809	Gene_expression of NUP214	3	0.65	1.35	1.24
85	INT167409	Regulation of Gene_expression of AKT1	8	0.56	4.86	1.23
86	INT200972	Positive_regulation of Gene_expression of UPF1	6	0.31	1.51	1.23
87	INT112823	Negative_regulation of Positive_regulation of MAPK14	5	0.36	1.49	1.22
88	INT103164	Binding of UPF1	4	0.29	4.15	1.22
89	INT220763	Regulation of Phosphorylation of PRKCA	3	0.29	0.84	1.22
90	INT219752	Localization of EXOSC1	4	0.78	6.92	1.19
91	INT135556	Localization of AKT1	38	0.69	12.78	1.17
92	INT118792	Regulation of Positive_regulation of AKT1	8	0.61	3.73	1.15
93	INT159361	Negative_regulation of Positive_regulation of SMG1	1	0.57	0.98	1.15
94	INT107592	Gene_expression of SMG1	42	0.74	11.16	1.13
95	INT176147	Regulation of Phosphorylation of AKT1	14	0.41	6.41	1.13
96	INT124135	Positive_regulation of Gene_expression of YWHAZ	2	0.45	0.21	1.05
97	INT67638	Positive_regulation of PSMA5	1	0.21	1.15	1.05
98	INT13882	Binding of PSMB9	3	0.15	2.84	1
99	INT27314	Negative_regulation of CNOT4	4	0.00	1.64	0.98
100	INT78322	Positive_regulation of PSME1	2	0.44	1.8	0.95
101	INT144289	Negative_regulation of Positive_regulation of PSMC6	1	0.41	0.56	0.92
102	INT67863	Positive_regulation of Negative_regulation of ETF1	1	0.35	0.14	0.92
103	INT144287	Positive_regulation of PSMC6	1	0.49	0.56	0.92
104	INT194875	Regulation of Negative_regulation of MAPK14	1	0.04	2.39	0.91
105	INT81925	Positive_regulation of Positive_regulation of HSPA1B	1	0.02	0.74	0.91
106	INT156641	Positive_regulation of CNOT4	4	0.07	3.19	0.9
107	INT120393	Negative_regulation of PRKCD	3	0.22	1.07	0.86
108	INT120396	Positive_regulation of Localization of PRKCD	1	0.26	0.42	0.85
109	INT120392	Localization of PRKCD	1	0.39	0.4	0.83
110	INT182167	Transcription of DCPS	1	0.11	1.94	0.82
111	INT355989	Positive_regulation of Localization of DCPS	1	0.05	1.83	0.8
112	INT78323	Negative_regulation of PSME1	1	0.37	0.5	0.78
113	INT79568	Regulation of Protein_catabolism of PRKCA	1	0.45	0.1	0.76
114	INT108590	Negative_regulation of Negative_regulation of PSMA5	1	0.57	0.92	0.75
115	INT85349	Negative_regulation of Localization of PRKCA	1	0.09	0	0.74
116	INT131433	Phosphorylation of MAPKAPK2	3	0.30	0.99	0.73
117	INT82366	Positive_regulation of Protein_catabolism of PRKCA	1	0.49	0	0.73
118	INT187506	Binding of Cebpg	7	0.47	2.27	0.72
119	INT182182	Positive_regulation of Positive_regulation of DCPS	4	0.08	3.32	0.7
120	INT38283	Positive_regulation of Cebpg	2	0.04	1.96	0.69
121	INT299338	Negative_regulation of Regulation of AKT1	2	0.31	2.32	0.68
122	INT139840	Positive_regulation of Negative_regulation of MAPK14	2	0.21	1.55	0.67
123	INT200961	Transcription of UPF1	2	0.01	0.52	0.67
124	INT108586	Positive_regulation of Negative_regulation of PSMA5	1	0.49	0.82	0.67
125	INT70216	Gene_expression of HSPB1	8	0.78	4.81	0.64
126	INT17646	Gene_expression of HSPA8	8	0.77	6.75	0.64
127	INT166024	Protein_catabolism of AKT1	5	0.46	2.6	0.64
128	INT304293	Positive_regulation of Negative_regulation of DCPS	2	0.08	3.17	0.64
129	INT200949	Negative_regulation of Gene_expression of UPF1	1	0.01	0.81	0.64
130	INT225072	Binding of ETF1	1	0.02	2.55	0.63
131	INT156169	Binding of SMG1	8	0.35	2.84	0.62
132	INT145142	Gene_expression of RPL5	3	0.12	1.54	0.62
133	INT67860	Positive_regulation of ETF1	3	0.23	0.49	0.62
134	INT89100	Gene_expression of CNOT1	7	0.65	1.76	0.59
135	INT123131	Negative_regulation of Negative_regulation of AKT1	6	0.42	3.23	0.58
136	INT17109	Regulation of Gene_expression of PSMD1	3	0.44	0.86	0.58
137	INT159634	Negative_regulation of Positive_regulation of DCPS	2	0.13	2.39	0.58
138	INT45724	Positive_regulation of Lipc	2	0.08	0.84	0.58
139	INT184815	Regulation of ETF1	3	0.40	1.83	0.54
140	INT16681	Positive_regulation of PSMC2	1	0.07	0	0.54
141	INT209936	Negative_regulation of Gene_expression of MAPK14	7	0.20	4.95	0.53
142	INT214855	Regulation of Positive_regulation of CNOT4	1	0.02	0.66	0.53
143	INT280711	Positive_regulation of Gene_expression of Cebpg	1	0.49	0	0.52
144	INT282809	Negative_regulation of Positive_regulation of YWHAZ	1	0.03	1.07	0.52
145	INT182178	Regulation of Gene_expression of DCPS	4	0.07	3.16	0.51
146	INT67864	Positive_regulation of Positive_regulation of ETF1	2	0.23	0.07	0.5
147	INT35619	Positive_regulation of Localization of RNPS1	1	0.01	0	0.49
148	INT120390	Phosphorylation of PRKCD	1	0.33	0.38	0.49
149	INT304297	Negative_regulation of Negative_regulation of DCPS	4	0.08	4.43	0.47
150	INT121027	Regulation of Phosphorylation of MAPK14	2	0.38	1.1	0.46
151	INT67861	Negative_regulation of Positive_regulation of ETF1	1	0.22	0.07	0.46
152	INT254389	Negative_regulation of Gene_expression of DCPS	6	0.08	7.26	0.44
153	INT173625	Positive_regulation of Localization of MAPK14	3	0.17	1.05	0.44
154	INT349073	Localization of ETF1	1	0.11	0	0.44
155	INT179170	Protein_catabolism of MAPK14	3	0.43	0.88	0.43
156	INT350879	Negative_regulation of Localization of PSMD1	1	0.05	0.43	0.43
157	INT202762	Gene_expression of PSMD3	8	0.47	1.44	0.42
158	INT255902	Positive_regulation of Binding of MAPK14	1	0.17	0.93	0.42
159	INT200975	Positive_regulation of Transcription of UPF1	1	0.01	0.22	0.42
160	INT280564	Negative_regulation of Gene_expression of PSMB9	5	0.54	5.99	0.41
161	INT120394	Positive_regulation of PRKCD	2	0.26	1.58	0.41
162	INT78324	Regulation of PSME1	1	0.61	0.49	0.41
163	INT156643	Positive_regulation of Positive_regulation of CNOT4	2	0.05	1.64	0.39
164	INT111872	Binding of CNOT4	4	0.02	1.11	0.37
165	INT280560	Positive_regulation of Gene_expression of PSMB9	7	0.64	6.44	0.36
166	INT76855	Negative_regulation of Gene_expression of PRKCA	4	0.30	1.8	0.36
167	INT335718	Regulation of Gene_expression of PSMD2	1	0.09	0.07	0.35
168	INT41179	Negative_regulation of EXOSC3	1	0.42	0.08	0.35
169	INT11689	Binding of PSMD2	16	0.36	2.77	0.34
170	INT57019	Gene_expression of PSMB1	1	0.38	0	0.34
171	INT120391	Negative_regulation of Localization of PRKCD	1	0.22	0	0.34
172	INT159633	Negative_regulation of Localization of DCPS	1	0.13	0.1	0.34
173	INT120398	Positive_regulation of Positive_regulation of PRKCD	1	0.26	0	0.33
174	INT156647	Transcription of CNOT4	1	0.07	0.79	0.32
175	INT156650	Positive_regulation of Transcription of CNOT4	1	0.05	0.79	0.32
176	INT85944	Binding of ELAVL1	5	0.07	1.11	0.31
177	INT187502	Positive_regulation of Cebpg	3	0.67	0.56	0.3
178	INT105142	Positive_regulation of HSPB1	3	0.70	1.08	0.3
179	INT280707	Gene_expression of Cebpg	4	0.75	0.37	0.29
180	INT164993	Positive_regulation of Gene_expression of SMG1	4	0.66	0.69	0.29
181	INT158048	Gene_expression of MAPKAPK2	2	0.28	0.79	0.29
182	INT11688	Binding of PSMD3	5	0.36	1.17	0.28
183	INT255923	Positive_regulation of Regulation of MAPK14	1	0.17	0.41	0.28
184	INT210645	Regulation of SMG1	5	0.40	1.15	0.27
185	INT118490	Regulation of CNOT4	2	0.02	1.18	0.27
186	INT281933	Localization of YWHAZ	2	0.09	1.08	0.27
187	INT76252	Positive_regulation of NUP214	1	0.45	0.17	0.27
188	INT156707	Positive_regulation of SET	6	0.49	1.14	0.26
189	INT89035	Positive_regulation of Gene_expression of HSPA8	1	0.69	1.8	0.26
190	INT240203	Regulation of Transcription of UPF1	1	0.01	0.3	0.26
191	INT44599	Gene_expression of CNOT4	4	0.40	3.09	0.25
192	INT318671	Transcription of Cebpg	1	0.67	2.35	0.25
193	INT173656	Negative_regulation of Cebpg	4	0.57	1.23	0.24
194	INT131823	Negative_regulation of PSMB6	2	0.01	0.09	0.24
195	INT171685	Phosphorylation of HSPB1	2	0.69	0.39	0.24
196	INT35618	Localization of RNPS1	1	0.01	0	0.24
197	INT120649	Localization of UPF1	3	0.03	0.93	0.22
198	INT322282	Localization of PSMD2	2	0.20	1.42	0.22
199	INT3239	Negative_regulation of ELAVL1	1	0.41	0.25	0.22
200	INT158050	Regulation of MAPKAPK2	1	0.00	0.8	0.22