GO:0016779

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Name nucleotidyltransferase activity
Categary Function
Go Slim Yes
Go Link GO:0016779
Unique Molecular Interactions 98
Total Molecular Interactions 134
Total Single Events 1005
Pain Genes Associated 22

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for nucleotidyltransferase activity. They are ordered first by their pain relevance and then by number of times they were reported for nucleotidyltransferase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT109739 Binding of ITPA and Pcyt1b 1 0.16 0.72 1.6
2 INT43796 Binding of CDS1 and Adra2a 1 0.06 0 0.86
3 INT61165 Binding of Pag1 and Pcyt1a 1 0.01 0.33 0.73
4 INT61164 Binding of Pomc and Pcyt1a 1 0.17 0.24 0.61
5 INT305851 Polk Positive_regulation of Gene_expression of Tslp 1 0.29 0.9 0.51
6 INT189688 PRKCA Regulation of Transcription of TERT 1 0.13 0.2 0.5
7 INT212806 Rngtt Negative_regulation of Gene_expression of Nos2 1 0.03 0.9 0.49
8 INT353631 Oas1a Positive_regulation of Klkb1 1 0.00 0 0.44
9 INT305853 Polk Regulation of Gene_expression of Hand2 1 0.12 0.93 0.35
10 INT305856 Polk Regulation of Gene_expression of TH1L 1 0.43 0.93 0.35
11 INT189687 INSRR Negative_regulation of Transcription of TERT 1 0.00 0.24 0.35
12 INT75643 NCOR2 Positive_regulation of Positive_regulation of EIF2B3 1 0.00 0 0.33
13 INT75641 AR Positive_regulation of Positive_regulation of EIF2B3 1 0.02 0 0.33
14 INT51088 Binding of CDS1 and PRMT1 1 0.06 0 0.28
15 INT305849 Polk Positive_regulation of Gene_expression of Hand2 1 0.08 0.76 0.27
16 INT305854 Polk Regulation of Gene_expression of Atp11c 1 0.05 0.73 0.26
17 INT318075 Polr1a Negative_regulation of interleukin-17 1 0.00 0.17 0.24
18 INT305850 Polk Positive_regulation of Gene_expression of dp 1 0.07 0.64 0.21
19 INT305848 Polk Positive_regulation of dp 1 0.09 0 0.19
20 INT302295 PPARA Regulation of OAS2 1 0.01 0.72 0.17
21 INT305857 Polk Regulation of Gene_expression of IFN1@ 1 0.31 0.74 0.17
22 INT330430 ALDOA Positive_regulation of Pcyt2 1 0.01 0.47 0.17
23 INT76196 Binding of HTR1A and EIF2B3 1 0.06 0 0.17
24 INT305846 Polk Positive_regulation of Gene_expression of Il4 1 0.13 0.24 0.15
25 INT212808 Rngtt Negative_regulation of Gene_expression of Ptger2 1 0.00 0.31 0.12
26 INT285948 IL17A Regulation of Gene_expression of TERT 1 0.00 0.58 0.11
27 INT305855 Polk Regulation of Atp11c 1 0.02 0.73 0.11
28 INT199284 Binding of Polr2a and Vmn1r66 1 0.00 0.19 0.11
29 INT212814 Rngtt Negative_regulation of Gene_expression of Tlr4 1 0.00 0.08 0.1
30 INT189702 CHKB Regulation of Gene_expression of TERT 1 0.06 0.55 0.1
31 INT212807 Rngtt Negative_regulation of Nos2 1 0.03 0.08 0.1
32 INT212811 Rngtt Negative_regulation of Tlr4 1 0.00 0.08 0.1
33 INT318074 Polr1a Negative_regulation of Gene_expression of Il2 1 0.00 0.46 0.08
34 INT244130 Binding of CASP1 and RNGTT 1 0.07 0.24 0.07
35 INT244131 Binding of RNGTT and NLRP1 1 0.11 0.24 0.07
36 INT211875 Binding of CDS1 and SMUG1 1 0.03 1.04 0.07
37 INT349886 Negative_regulation of Binding of Pcyt1a and Twist1 1 0.02 1.21 0.06
38 INT349887 Binding of Pcyt1a and Twist1 1 0.02 1.21 0.06
39 INT189677 CHKB Regulation of Transcription of TERT 1 0.10 1 0.05
40 INT189679 INSRR Regulation of Transcription of TERT 1 0.00 1 0.05
41 INT310727 Binding of DKC1 and TERT 1 0.23 0.91 0.05
42 INT220812 Tert Positive_regulation of Gene_expression of hl 1 0.01 0.14 0.04
43 INT265451 CSPG4 Positive_regulation of RNGTT 1 0.03 0.24 0.04
44 INT220811 Tert Positive_regulation of Gene_expression of Krt36 1 0.41 0.14 0.04
45 INT278212 Binding of Polr2a and Cytip 1 0.06 0.07 0.04
46 INT220808 Tert Positive_regulation of Gene_expression of Krt31 1 0.43 0.14 0.04
47 INT244129 Binding of RNGTT and NOD1 1 0.11 0 0.04
48 INT285944 IL6 Positive_regulation of Gene_expression of TERT 1 0.01 0.36 0.04
49 INT332944 Binding of HAT1 and Polr2a 1 0.00 0.27 0.03
50 INT330426 Pcyt2 Regulation of Gene_expression of Aldh2 1 0.09 0.46 0.03
51 INT250226 Binding of Camp and Rngtt 1 0.14 0.85 0.03
52 INT296163 Mcph1 Regulation of Tert 1 0.03 0.19 0
53 INT313120 Positive_regulation of Binding of Polr2a and Carf 1 0.06 0.69 0
54 INT293615 Nmnat2 Positive_regulation of Nmnat1 1 0.19 0.79 0
55 INT305845 Polk Positive_regulation of Regulation of Hand2 1 0.08 0.34 0
56 INT313307 TERT Positive_regulation of NFE2L2 1 0.01 0 0
57 INT217779 POLR2B Regulation of Gene_expression of RASGRP1 1 0.01 0.2 0
58 INT331091 Tert Positive_regulation of Positive_regulation of Cd4 1 0.24 0.76 0
59 INT189703 MZF1 Regulation of TERT 1 0.03 0.46 0
60 INT265458 RNGTT Positive_regulation of Gene_expression of ROS1 1 0.08 0.88 0
61 INT285941 IL6 Regulation of Gene_expression of TERT 1 0.01 0.12 0
62 INT217785 POLR2B Regulation of Gene_expression of MAP3K3 1 0.06 0.2 0
63 INT220819 Myc Regulation of Transcription of Tert 1 0.44 0.1 0
64 INT220813 Tert Positive_regulation of Terc 1 0.51 0.17 0
65 INT293613 Wld Positive_regulation of Nmnat1 1 0.42 0.79 0
66 INT189705 INSRR Negative_regulation of Gene_expression of TERT 1 0.00 0.46 0
67 INT220817 Tert Regulation of hl 1 0.01 0.96 0
68 INT189697 INSRR Regulation of Gene_expression of TERT 1 0.00 0.46 0
69 INT270759 Binding of HSD11B1 and TERT 1 0.07 1.67 0
70 INT313115 Binding of Polr2a and Carf 1 0.05 0.69 0
71 INT189690 USF1 Regulation of TERT 1 0.05 0.46 0
72 INT189669 INSRR Regulation of TERT 1 0.00 0 0
73 INT189685 USF1 Positive_regulation of Transcription of TERT 1 0.05 0.27 0
74 INT189698 CHKB Regulation of TERT 1 0.06 0 0
75 INT355663 Binding of CA5P and OAS1 1 0.00 0.47 0
76 INT189673 BCL2 Positive_regulation of Transcription of TERT 1 0.09 0 0
77 INT305852 Polk Positive_regulation of Positive_regulation of Il4 1 0.13 0.08 0
78 INT189676 CCND3 Regulation of Transcription of TERT 1 0.02 0.06 0
79 INT347292 AREG Negative_regulation of Gene_expression of TERT 1 0.02 0.78 0
80 INT189672 Positive_regulation of INSRR Regulation of Transcription of TERT 1 0.00 0.23 0
81 INT189682 CHKB Negative_regulation of Gene_expression of TERT 1 0.10 0.46 0
82 INT293617 Wld Positive_regulation of Nmnat2 1 0.65 1.9 0
83 INT220816 Tert Regulation of Myc 1 0.44 0.1 0
84 INT220809 Tert Regulation of Regulation of Myc 1 0.32 0.25 0
85 INT274387 Binding of POLA1 and IGSF9 1 0.01 0.58 0
86 INT189684 RNF2 Regulation of TERT 1 0.02 0.46 0
87 INT352860 Positive_regulation of POLR2B Positive_regulation of Positive_regulation of IKBKAP 1 0.03 0.74 0
88 INT220820 Binding of Myc and Tert 1 0.26 0.19 0
89 INT301472 Binding of Polr2a and Smyd3 1 0.06 0.08 0
90 INT313302 Regulation of TERT Positive_regulation of SQSTM1 1 0.01 0 0
91 INT305847 Polk Positive_regulation of Hand2 1 0.09 0.34 0
92 INT285937 IL6 Regulation of TERT 1 0.01 0.12 0
93 INT313291 TERT Positive_regulation of SQSTM1 1 0.02 0 0
94 INT251822 Binding of POLG and C10orf2 1 0.42 0.29 0
95 INT191413 Tert Positive_regulation of Nqo1 1 0.02 0.84 0
96 INT186989 Binding of Akt1 and Tert 1 0.00 0.61 0
97 INT301476 Binding of Polr2a and Smyd2 1 0.08 0.13 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for nucleotidyltransferase activity. They are ordered first by their pain relevance and then by number of times they were reported in nucleotidyltransferase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT121496 Gene_expression of TERT 107 0.78 45.6 7.42
2 INT20673 Binding of CDS1 18 0.31 1.96 5.72
3 INT4958 Gene_expression of Pcyt1b 18 0.65 3.4 5.66
4 INT121494 Transcription of TERT 64 0.69 10.03 5.55
5 INT75645 Binding of EIF2B3 10 0.07 0.21 4.9
6 INT33399 Negative_regulation of CDS1 12 0.37 1.97 4.22
7 INT20672 Gene_expression of CDS1 19 0.76 8.19 4.08
8 INT157399 Localization of Pcyt1b 9 0.69 2.3 2.54
9 INT133194 Negative_regulation of TERT 23 0.48 4.01 2.45
10 INT189770 Positive_regulation of Transcription of TERT 1 0.28 1.36 2.14
11 INT189766 Regulation of Transcription of TERT 1 0.25 3.48 1.99
12 INT85178 Gene_expression of OAS2 10 0.21 4.17 1.93
13 INT244169 Localization of RNGTT 8 0.23 1.92 1.81
14 INT33400 Regulation of CDS1 8 0.29 5.12 1.79
15 INT305832 Gene_expression of Polk 1 0.48 0.49 1.64
16 INT147403 Regulation of Gene_expression of TERT 11 0.27 3.45 1.54
17 INT220783 Gene_expression of Tert 39 0.77 12.55 1.49
18 INT269141 Gene_expression of Oas1a 2 0.20 0 1.48
19 INT29421 Positive_regulation of CDS1 7 0.46 3.16 1.47
20 INT129712 Positive_regulation of Gene_expression of TERT 12 0.70 7.3 1.44
21 INT75647 Positive_regulation of Binding of EIF2B3 3 0.07 0.11 1.42
22 INT133193 Positive_regulation of TERT 16 0.50 6.43 1.38
23 INT61163 Binding of Pcyt1a 1 0.16 0.57 1.32
24 INT147607 Binding of TERT 16 0.48 12.36 1.31
25 INT189736 Regulation of TERT 22 0.40 3.58 1.29
26 INT38916 Positive_regulation of Tert 3 0.33 1.92 1.28
27 INT145416 Binding of Pcyt1b 6 0.22 0.48 1.19
28 INT178674 Positive_regulation of RNGTT 6 0.15 1.05 1.09
29 INT133195 Negative_regulation of Transcription of TERT 4 0.42 2.9 1.08
30 INT58847 Positive_regulation of Pcyt1b 5 0.32 0.76 1.06
31 INT37080 Negative_regulation of OAS2 4 0.05 1.3 0.89
32 INT303636 Gene_expression of OAS1 6 0.56 2.29 0.87
33 INT293581 Positive_regulation of Nmnat2 1 0.59 4.33 0.86
34 INT189734 Negative_regulation of Gene_expression of TERT 8 0.24 1.84 0.85
35 INT147183 Gene_expression of RNGTT 16 0.37 2.43 0.82
36 INT17246 Negative_regulation of POLG 16 0.56 9.69 0.79
37 INT75646 Positive_regulation of EIF2B3 2 0.06 0.11 0.68
38 INT93752 Positive_regulation of OAS2 2 0.13 0.67 0.64
39 INT244157 Negative_regulation of RNGTT 2 0.12 0.17 0.61
40 INT100941 Positive_regulation of Gene_expression of OAS2 2 0.16 0.53 0.6
41 INT318072 Gene_expression of Polr1a 1 0.01 0.81 0.56
42 INT33401 Negative_regulation of Negative_regulation of CDS1 1 0.37 0 0.53
43 INT189756 Positive_regulation of Phosphorylation of TERT 1 0.28 0.2 0.5
44 INT189728 Phosphorylation of TERT 1 0.34 0.2 0.5
45 INT220787 Localization of Tert 5 0.69 0.87 0.49
46 INT130141 Phosphorylation of POLR2B 1 0.29 0.57 0.47
47 INT224278 Transcription of Pcyt1b 1 0.29 0.41 0.45
48 INT158837 Binding of POLG 4 0.37 4.69 0.44
49 INT244163 Positive_regulation of Localization of RNGTT 1 0.15 0.08 0.43
50 INT305826 Regulation of Gene_expression of Polk 1 0.28 0 0.43
51 INT212803 Gene_expression of Rngtt 6 0.37 0.47 0.37
52 INT80068 Positive_regulation of Pcyt2 1 0.00 0 0.36
53 INT320041 Negative_regulation of Gene_expression of CDS1 1 0.03 0.44 0.35
54 INT305817 Positive_regulation of Gene_expression of Polk 1 0.36 0.05 0.34
55 INT189760 Negative_regulation of Negative_regulation of TERT 1 0.24 0.11 0.34
56 INT189739 Negative_regulation of Regulation of TERT 1 0.18 0.17 0.32
57 INT37112 Negative_regulation of Binding of CDS1 1 0.37 0 0.31
58 INT86395 Negative_regulation of Binding of EIF2B3 1 0.05 0.06 0.3
59 INT305837 Regulation of Polk 1 0.28 0 0.28
60 INT220770 Binding of Tert 7 0.37 1.09 0.27
61 INT349882 Gene_expression of Pcyt1a 1 0.05 8.79 0.27
62 INT136760 Regulation of OAS2 1 0.01 0.21 0.27
63 INT119928 Localization of CDS1 3 0.60 1.94 0.26
64 INT293582 Negative_regulation of Positive_regulation of Nmnat2 1 0.36 0.78 0.26
65 INT244149 Regulation of Gene_expression of RNGTT 1 0.13 0.99 0.26
66 INT220785 Positive_regulation of Tert 15 0.68 6.9 0.25
67 INT138715 Gene_expression of POLG 12 0.66 6.97 0.23
68 INT305841 Binding of Polk 1 0.23 0.43 0.22
69 INT349874 Positive_regulation of Gene_expression of Pcyt1a 1 0.04 3.54 0.22
70 INT293588 Gene_expression of Nmnat2 1 0.76 8.52 0.21
71 INT220777 Positive_regulation of Gene_expression of Tert 9 0.68 2.34 0.18
72 INT169582 Phosphorylation of POLG 2 0.54 1.98 0.18
73 INT250224 Regulation of Rngtt 1 0.25 0.77 0.18
74 INT338841 Regulation of Polr2a 1 0.01 0.08 0.17
75 INT338840 Protein_catabolism of Polr2a 1 0.02 0.08 0.17
76 INT169865 Protein_catabolism of Pcyt1b 1 0.52 0.1 0.16
77 INT244142 Transcription of RNGTT 1 0.21 0.13 0.16
78 INT305827 Negative_regulation of Gene_expression of Polk 1 0.26 0 0.16
79 INT220767 Regulation of Tert 1 0.53 1 0.16
80 INT288390 Positive_regulation of Gene_expression of Pcyt1b 1 0.07 0.07 0.16
81 INT20012 Positive_regulation of OAS1 3 0.45 1.14 0.15
82 INT270032 Gene_expression of Nmnat1 2 0.72 7.19 0.15
83 INT74158 Positive_regulation of Gene_expression of CDS1 2 0.43 1.05 0.15
84 INT200282 Phosphorylation of Polr2a 1 0.04 0.14 0.15
85 INT220774 Negative_regulation of Gene_expression of Tert 1 0.58 1.09 0.14
86 INT189761 Positive_regulation of Regulation of TERT 1 0.19 0.14 0.14
87 INT115575 Regulation of Gene_expression of Pcyt1a 1 0.28 0 0.13
88 INT115576 Regulation of Pcyt1a 1 0.38 0 0.13
89 INT205561 Positive_regulation of Localization of Pcyt1b 1 0.11 0.25 0.13
90 INT260367 Regulation of Gene_expression of Pcyt1b 2 0.16 0 0.12
91 INT190557 Transcription of Polr2a 1 0.09 0.51 0.12
92 INT302679 Negative_regulation of Localization of POLG 1 0.39 0.99 0.11
93 INT186980 Transcription of Tert 1 0.34 0.34 0.11
94 INT186973 Regulation of Transcription of Tert 1 0.21 0.34 0.11
95 INT190499 Regulation of OAS1 2 0.04 0.99 0.1
96 INT250223 Negative_regulation of Rngtt 1 0.24 0.53 0.1
97 INT302692 Localization of POLG 1 0.69 0.99 0.1
98 INT292827 Positive_regulation of Pcyt1a 2 0.04 2.21 0.09
99 INT210442 Negative_regulation of Pcyt1b 2 0.24 0 0.09
100 INT293606 Negative_regulation of Gene_expression of Nmnat2 1 0.42 0.54 0.09
101 INT251829 Positive_regulation of POLG 1 0.53 1.5 0.08
102 INT46700 Negative_regulation of Pcyt1a 1 0.42 0.26 0.08
103 INT220780 Regulation of Gene_expression of Tert 1 0.44 0 0.08
104 INT293611 Localization of Nmnat2 1 0.69 3.12 0.08
105 INT115577 Gene_expression of Pcyt1a 3 0.42 0 0.07
106 INT250225 Positive_regulation of Rngtt 2 0.28 0.78 0.07
107 INT20671 Regulation of Binding of CDS1 1 0.07 0 0.07
108 INT270031 Positive_regulation of Gene_expression of Nmnat1 2 0.65 1.73 0.06
109 INT349877 Negative_regulation of Localization of Pcyt1a 1 0.03 1.09 0.05
110 INT186977 Gene_expression of Tert 1 0.36 1.49 0.05
111 INT349875 Positive_regulation of Localization of Pcyt1a 1 0.03 1.09 0.05
112 INT212802 Negative_regulation of Gene_expression of Rngtt 1 0.05 0 0.05
113 INT349878 Localization of Pcyt1a 1 0.05 1.09 0.05
114 INT251827 Regulation of POLG 3 0.59 2.94 0.04
115 INT220784 Regulation of Regulation of Tert 1 0.39 0 0.04
116 INT244172 Regulation of Transcription of RNGTT 1 0.13 0.06 0.04
117 INT220786 Negative_regulation of Tert 8 0.43 2.55 0.03
118 INT301441 Binding of Polr2a 3 0.10 0.41 0.03
119 INT175888 Gene_expression of POLR2B 2 0.04 0.32 0.03
120 INT274377 Localization of TERT 3 0.70 0.78 0
121 INT298408 Transcription of POLR2B 3 0.12 2.78 0
122 INT175893 Regulation of POLR2B 2 0.08 1.34 0
123 INT220792 Transcription of Tert 2 0.71 0.56 0
124 INT223278 Positive_regulation of Binding of TERT 2 0.44 1.35 0
125 INT266162 Transcription of POLG 2 0.68 0.76 0
126 INT186978 Positive_regulation of Positive_regulation of Tert 1 0.22 0.44 0
127 INT311975 Regulation of Gene_expression of OAS1 1 0.11 0.08 0
128 INT293597 Negative_regulation of Negative_regulation of Nmnat2 1 0.36 0.15 0
129 INT186985 Positive_regulation of Transcription of Tert 1 0.24 0 0
130 INT186976 Binding of Tert 1 0.17 0.55 0
131 INT310442 Gene_expression of POLA1 1 0.30 0.97 0
132 INT175901 Negative_regulation of POLR2B 1 0.00 0.34 0
133 INT298404 Regulation of Transcription of POLR2B 1 0.05 1.02 0
134 INT293610 Transcription of Nmnat2 1 0.45 0.54 0
135 INT93751 Negative_regulation of Positive_regulation of OAS2 1 0.11 0.05 0
136 INT347316 Negative_regulation of Binding of TERT 1 0.18 0.26 0
137 INT293598 Negative_regulation of Binding of Nmnat2 1 0.36 1.3 0
138 INT293595 Negative_regulation of Localization of Nmnat2 1 0.36 0.86 0
139 INT189751 Regulation of Regulation of TERT 1 0.11 0.08 0
140 INT293589 Positive_regulation of Localization of Nmnat2 1 0.43 0.17 0
141 INT293585 Localization of Nmnat1 1 0.75 2.74 0
142 INT293599 Positive_regulation of Negative_regulation of Nmnat2 1 0.43 1.02 0
143 INT293596 Positive_regulation of Gene_expression of Nmnat2 1 0.46 0.95 0
144 INT266161 Regulation of Negative_regulation of POLG 1 0.38 0.56 0
145 INT331373 Positive_regulation of Transcription of Tert 1 0.24 0.17 0
146 INT260376 Protein_catabolism of TERT 1 0.02 0.36 0
147 INT266164 Negative_regulation of Gene_expression of POLG 1 0.41 1.08 0
148 INT186974 Negative_regulation of Transcription of Tert 1 0.27 0 0
149 INT292830 Transcription of Pcyt1a 1 0.03 0.5 0
150 INT293608 Binding of Nmnat2 1 0.32 2.8 0
151 INT293591 Regulation of Localization of Nmnat1 1 0.37 0.77 0
152 INT310440 Positive_regulation of POLA1 1 0.18 0.09 0
153 INT293612 Negative_regulation of Nmnat1 1 0.35 0.46 0
154 INT352861 Positive_regulation of Transcription of POLR2B 1 0.04 0.73 0
155 INT265096 Negative_regulation of Binding of Pcyt1b 1 0.15 0 0
156 INT266170 Negative_regulation of Transcription of POLG 1 0.36 1.43 0
157 INT293594 Positive_regulation of Nmnat1 1 0.57 1.41 0
158 INT346970 Binding of POLR2B 1 0.03 0.36 0
159 INT251832 Positive_regulation of Positive_regulation of POLG 1 0.35 0.28 0
160 INT352872 Positive_regulation of POLR2B 1 0.05 0.72 0
161 INT267044 Negative_regulation of Gene_expression of Pcyt1a 1 0.03 0 0
162 INT355666 Binding of OAS1 1 0.27 0.47 0
163 INT310439 Regulation of POLA1 1 0.24 2.21 0
164 INT251952 Negative_regulation of Localization of CDS1 1 0.28 0.44 0
165 INT310443 Negative_regulation of POLA1 1 0.16 0.31 0
166 INT186988 Negative_regulation of Gene_expression of Tert 1 0.27 1.06 0
167 INT293592 Negative_regulation of Nmnat2 1 0.50 8.75 0
168 INT293602 Transcription of Nmnat1 1 0.58 0.21 0
169 INT186986 Negative_regulation of Tert 1 0.27 0.61 0
170 INT293586 Binding of Nmnat1 1 0.35 1.78 0
171 INT293580 Protein_catabolism of Nmnat2 1 0.97 0.97 0
172 INT293593 Negative_regulation of Gene_expression of Nmnat1 1 0.35 0.52 0
173 INT186987 Regulation of Tert 1 0.13 0 0
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