GO:0016798

Name hydrolase activity, acting on glycosyl bonds Categary Function Go Slim Yes Go Link GO:0016798

Unique Molecular Interactions 155 Total Molecular Interactions 184 Total Single Events 2330 Pain Genes Associated 38

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for hydrolase activity, acting on glycosyl bonds. They are ordered first by their pain relevance and then by number of times they were reported for hydrolase activity, acting on glycosyl bonds. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT70946	Penk Positive_regulation of Hpse	1	0.34	0	2.65
2	INT26892	OGG1 Negative_regulation of Gene_expression of Gh1	1	0.12	0	2.53
3	INT317538	Binding of Neu3 and Mors1	1	0.00	0	1.51
4	INT109958	Binding of CRH and HPSE	1	0.10	0.72	1.46
5	INT169163	Binding of Calca and Ctbs	1	0.00	0.51	1.4
6	INT26893	OGG1 Negative_regulation of Gh1	1	0.12	0	1.37
7	INT168865	Cd38 Regulation of Wdtc1	1	0.03	0.12	1.35
8	INT115272	Neu1 Positive_regulation of Coq10a	1	0.43	0.41	1.35
9	INT115271	Neu1 Positive_regulation of Coq10a	1	0.01	0.41	1.35
10	INT2641	Binding of Pomc and Lct	2	0.31	0.57	1.32
11	INT168866	Binding of RYR1 and Cd38	1	0.02	0.17	1.28
12	INT195541	Lct Positive_regulation of Gene_expression of Grm2	1	0.02	0.4	1.27
13	INT60794	Binding of TREH and Chrna9	1	0.00	0	1.04
14	INT70947	Penk Regulation of Hpse	1	0.20	0	0.96
15	INT220145	HPSE Negative_regulation of Gene_expression of CRH	1	0.01	0.92	0.64
16	INT77120	Pomc Regulation of HYAL1	1	0.01	0	0.61
17	INT177358	Ptger1 Positive_regulation of Localization of AMY2A	1	0.00	0.56	0.54
18	INT177357	Ptger1 Positive_regulation of Gene_expression of AMY2A	1	0.00	0.56	0.54
19	INT60793	Negative_regulation of Binding of TREH and Chrna9	1	0.00	0	0.53
20	INT60788	Binding of TREH and BHLHE23	1	0.00	0	0.52
21	INT43646	Negative_regulation of Binding of Pomc and Lct	1	0.38	0	0.47
22	INT72203	GH1 Regulation of OGG1	1	0.10	0	0.46
23	INT352387	Binding of CFP and HPSE	1	0.01	1.25	0.46
24	INT177440	Binding of HPSE and Gnrh1	1	0.00	1.82	0.45
25	INT8356	Binding of YY1 and Smpd1	1	0.32	0	0.43
26	INT243682	IRF6 Positive_regulation of NEU2	1	0.01	0.18	0.43
27	INT61131	NEU2 Positive_regulation of CPQ	1	0.01	0	0.41
28	INT354062	Avp Regulation of Lyz2	1	0.00	0.12	0.38
29	INT129769	Binding of LYZ and S100B	1	0.33	0.86	0.37
30	INT129768	Binding of LYZ and PTPRC	1	0.34	0.87	0.37
31	INT87769	Binding of Acot1 and Treh	1	0.00	0	0.35
32	INT210263	Mtx1 Regulation of Gene_expression of LYZ	1	0.00	0.33	0.32
33	INT210935	Il6 Positive_regulation of Smpd1	1	0.02	0.46	0.3
34	INT223965	Binding of AMY2A and Bglap	1	0.05	1.5	0.28
35	INT245640	Nr3c2 Regulation of Positive_regulation of Hpse	1	0.08	0.66	0.26
36	INT35179	Binding of STT3A and LYZ	1	0.07	0.38	0.25
37	INT327383	Il13 Positive_regulation of Gene_expression of Cd38	1	0.19	0	0.25
38	INT149940	Smpd1 Positive_regulation of spc	1	0.03	0.19	0.24
39	INT195544	Lct Positive_regulation of Transcription of Grm2	1	0.01	0.06	0.24
40	INT287101	Binding of Bdnf and Mutyh	1	0.04	0.58	0.24
41	INT195547	Lct Positive_regulation of Transcription of Grm3	1	0.00	0.06	0.24
42	INT184192	IL1B Positive_regulation of SPAM1	1	0.04	0.49	0.24
43	INT195553	Lct Positive_regulation of Grm2	1	0.02	0.05	0.23
44	INT41787	IFNA2 Negative_regulation of Glb1	1	0.04	0.09	0.23
45	INT184191	IL1B Positive_regulation of Gene_expression of SPAM1	1	0.03	0.59	0.23
46	INT195548	Lct Positive_regulation of Grm3	1	0.00	0.06	0.23
47	INT173358	Gnaq Positive_regulation of SMPD1	1	0.01	0.13	0.23
48	INT319555	gr Positive_regulation of Positive_regulation of Hpse	1	0.09	0.11	0.22
49	INT222499	Il10 Regulation of Positive_regulation of Hpse	1	0.00	0.8	0.19
50	INT222531	Il6 Positive_regulation of Hpse	1	0.00	0.61	0.18
51	INT222414	Tlr4 Positive_regulation of Hpse	1	0.00	0.61	0.18
52	INT184194	Binding of HRAS and SPAM1	1	0.00	0.26	0.17
53	INT245641	Nr3c2 Regulation of Gene_expression of Hpse	1	0.14	2.67	0.17
54	INT222505	Gene_expression of Crh Negative_regulation of Gene_expression of Hpse	1	0.02	0.55	0.17
55	INT245314	Binding of HYAL1 and MMP2	1	0.16	0.29	0.15
56	INT245312	Negative_regulation of Binding of HYAL1 and MMP2	1	0.19	0.29	0.15
57	INT222420	Tlr4 Positive_regulation of Positive_regulation of Hpse	1	0.00	0.67	0.15
58	INT222551	Il6 Positive_regulation of Positive_regulation of Hpse	1	0.01	0.5	0.13
59	INT354888	Amy1 Regulation of Il10	1	0.02	1.41	0.13
60	INT354885	Amy1 Regulation of Gene_expression of Il10	1	0.03	1.41	0.13
61	INT311191	ecs Negative_regulation of HPSE	1	0.00	0.94	0.12
62	INT134615	Binding of Neu3 and Trpv1	1	0.01	0.06	0.11
63	INT190631	Gusb Positive_regulation of Tlr4	1	0.08	0.44	0.11
64	INT341879	Oxt Negative_regulation of Positive_regulation of Hpse	1	0.01	0.83	0.11
65	INT214957	Vamp2 Regulation of Neu3	1	0.00	0	0.1
66	INT214954	Vamp1 Regulation of Neu3	1	0.00	0	0.1
67	INT186539	Crh Regulation of Hpse	1	0.09	0.52	0.1
68	INT204904	Tlr4 Positive_regulation of Hexb	1	0.14	0.09	0.09
69	INT223088	Binding of ELF3 and NAGLU	1	0.14	0.84	0.09
70	INT188964	Binding of AMBP and NAGLU	1	0.01	1.27	0.09
71	INT223089	Binding of IDS and NAGLU	1	0.26	0.72	0.09
72	INT204884	Tlr4 Negative_regulation of Negative_regulation of Hexb	1	0.13	0.09	0.09
73	INT354962	Gene_expression of Shank3 Positive_regulation of Gusb	1	0.10	0.45	0.08
74	INT186540	Binding of Cort and Hpse	1	0.05	0.92	0.08
75	INT245642	Nr3c1 Regulation of Gene_expression of Hpse	1	0.05	1.33	0.08
76	INT337072	Binding of Fmr1 and Gusb	1	0.19	1.55	0.08
77	INT249198	CD38 Positive_regulation of CA2	1	0.16	0.16	0.08
78	INT195549	Lct Positive_regulation of Rela	1	0.01	0	0.07
79	INT271493	Ctbs Negative_regulation of Hand1	1	0.04	0.63	0.07
80	INT159461	SCN5A Negative_regulation of HPSE	1	0.00	0	0.07
81	INT159463	Ptprn2 Negative_regulation of HPSE	1	0.00	0	0.07
82	INT211875	Binding of CDS1 and SMUG1	1	0.03	1.04	0.07
83	INT40240	CPOX Negative_regulation of Localization of LYZ	1	0.22	0.16	0.07
84	INT147112	LYZ Regulation of Binding of LTF	1	0.14	1.02	0.07
85	INT345297	Binding of NAGLU and Lcn2	1	0.01	1.24	0.07
86	INT330487	Binding of MME and HPSE	1	0.35	0	0.06
87	INT195551	Lct Regulation of Gene_expression of Grm2	1	0.01	0	0.05
88	INT178968	Slc7a2 Negative_regulation of Glb1	1	0.02	1.77	0.05
89	INT195221	Binding of CSRP1 and NAGLU	1	0.17	0.25	0.05
90	INT80067	Penk Positive_regulation of Gene_expression of Glb1	1	0.07	0.1	0.05
91	INT214033	OGG1 Negative_regulation of BPIFA4P	1	0.08	0.71	0.05
92	INT14440	Binding of GLB1 and NEU1	1	0.00	0.09	0.05
93	INT204906	Tlr4 Negative_regulation of Hexb	1	0.13	0.09	0.04
94	INT302982	Smpd1 Positive_regulation of Gene_expression of Smpd3	1	0.30	0.64	0.04
95	INT249158	CD38 Regulation of CA2	1	0.13	0.07	0.04
96	INT280616	Binding of Neu2 and Mpl	1	0.00	0.12	0.04
97	INT270330	Binding of HYAL1 and TIMP1	1	0.00	0.2	0.04
98	INT246786	Ogg1 Regulation of Phosphorylation of Tsc2	1	0.20	0.42	0.04
99	INT154339	Binding of IGLL1 and MAN1A1	1	0.00	0	0.03
100	INT246791	Tsc2 Regulation of Ogg1	1	0.27	0.56	0.03
101	INT314401	Binding of Ctbs and Gpsm2	1	0.10	0	0
102	INT327465	Binding of Cd4 and Neu1	1	0.06	0.73	0
103	INT191097	Neu1 Positive_regulation of Shc1	1	0.04	1.96	0
104	INT246784	Negative_regulation of Tsc2 Positive_regulation of Negative_regulation of Ogg1	1	0.20	0.43	0
105	INT306511	Binding of XRCC6 and Ung	1	0.00	0.78	0
106	INT246799	Pik3c3 Positive_regulation of Negative_regulation of Ogg1	1	0.04	0	0
107	INT286114	Binding of MSH6 and Mutyh	1	0.17	0	0
108	INT288588	Binding of Cav1 and Neu3	1	0.01	0	0
109	INT246796	Ros1 Positive_regulation of Negative_regulation of Ogg1	1	0.04	0	0
110	INT245589	Binding of Glb1 and B3galt6	1	0.01	0.94	0
111	INT300664	Binding of Gla and Thra	1	0.08	0	0
112	INT182403	Binding of OGG1 and XRCC1	1	0.35	0.14	0
113	INT286111	Binding of Rpa3 and Mutyh	1	0.30	0	0
114	INT185733	Hpse Positive_regulation of Gene_expression of Tnfrsf11b	1	0.20	0.24	0
115	INT240722	Cd38 Positive_regulation of Localization of Ca2	1	0.04	0.79	0
116	INT303822	Tdp1 Regulation of TREH	1	0.02	0.92	0
117	INT246809	Negative_regulation of Tsc2 Positive_regulation of Positive_regulation of Ogg1	1	0.20	0.45	0
118	INT291108	AGL Regulation of Gene_expression of PDK4	1	0.01	0	0
119	INT321126	Negative_regulation of Binding of F5 and Lyz2	1	0.00	0.32	0
120	INT283859	Binding of ACTN4 and TREH	1	0.00	1.61	0
121	INT246812	Ros1 Positive_regulation of Ogg1	1	0.05	0	0
122	INT321128	Binding of F5 and Lyz2	1	0.00	0.32	0
123	INT286115	Binding of APEX1 and Mutyh	1	0.10	0	0
124	INT272013	Binding of OGG1 and Tsc2	1	0.09	0.67	0
125	INT314398	Ptpn6 Regulation of Gene_expression of Ctbs	1	0.03	0	0
126	INT272010	Tsc2 Negative_regulation of OGG1	1	0.17	0.6	0
127	INT264864	Cd38 Positive_regulation of Localization of INS	1	0.06	0.51	0
128	INT322875	Binding of OSM and Lyz2	1	0.00	0	0
129	INT182407	Binding of NFYA and OGG1	1	0.02	0.07	0
130	INT70122	NAGLU Positive_regulation of Localization of Anpep	1	0.10	0	0
131	INT257341	Binding of Neu2 and Cyba	1	0.00	0.29	0
132	INT328422	Protein_catabolism of Neu1 Positive_regulation of Dnase2b	1	0.01	0.67	0
133	INT184196	GOPC Negative_regulation of HYAL1	1	0.02	0	0
134	INT246795	Ros1 Positive_regulation of Phosphorylation of Ogg1	1	0.05	0	0
135	INT162510	Binding of ITPR1 and HPSE	1	0.02	0.05	0
136	INT246810	Negative_regulation of Akt1 Positive_regulation of Ogg1	1	0.42	0	0
137	INT317597	Binding of Gnrh1 and Hpse	1	0.08	0	0
138	INT349105	Hyal1 Positive_regulation of Gene_expression of Il6	1	0.30	0.25	0
139	INT191837	Binding of SMUG1 and Airn	1	0.02	0.98	0
140	INT103769	AMY2A Positive_regulation of IFNA2	1	0.01	0.26	0
141	INT333637	Smpd1 Positive_regulation of IRF3	1	0.09	0.62	0
142	INT184195	IL1B Regulation of Gene_expression of SPAM1	1	0.02	0	0
143	INT222537	Binding of Nmu and Hpse	1	0.01	0.15	0
144	INT323185	Binding of LIG4 and OGG1	1	0.02	0.32	0
145	INT286109	Binding of Pcna and Mutyh	1	0.30	0	0
146	INT254044	Binding of BGLAP and NEU4	1	0.04	0.29	0
147	INT314679	NEU1 Negative_regulation of TP53	1	0.12	1.23	0
148	INT246800	Binding of Tsc2 and Ogg1	1	0.16	0.38	0
149	INT322874	Binding of PDCD10 and Lyz2	1	0.01	0	0

Single Events

The table below shows the top 100 pain related interactions that have been reported for hydrolase activity, acting on glycosyl bonds. They are ordered first by their pain relevance and then by number of times they were reported in hydrolase activity, acting on glycosyl bonds. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT13415	Positive_regulation of Hpse	58	0.70	24.9	25.53
2	INT12575	Regulation of Hpse	33	0.59	17.7	18.45
3	INT10585	Localization of NAGLU	53	0.80	23.32	12.75
4	INT49474	Gene_expression of Hpse	24	0.55	20.11	10.03
5	INT158796	Positive_regulation of SMUG1	67	0.70	38.97	8.98
6	INT162393	Gene_expression of SMUG1	58	0.75	38.78	7.7
7	INT78199	Gene_expression of Neu1	65	0.75	62.88	7.16
8	INT1973	Positive_regulation of NAGLU	36	0.65	14.78	7
9	INT20389	Localization of LYZ	19	0.79	4.58	6.25
10	INT9779	Gene_expression of Glb1	23	0.58	8.01	6.04
11	INT163540	Gene_expression of HYAL1	27	0.68	12.11	5.95
12	INT3731	Negative_regulation of Neu1	17	0.39	8.35	5.67
13	INT76313	Gene_expression of CD38	30	0.64	20.74	5.27
14	INT65554	Positive_regulation of Hpse	13	0.69	8.16	5.17
15	INT3165	Gene_expression of LYZ	25	0.65	16.72	5.16
16	INT171033	Localization of SMPD1	15	0.16	11.92	5.16
17	INT171019	Gene_expression of SMPD1	26	0.27	12.08	5.08
18	INT3163	Gene_expression of NAGLU	28	0.75	15.23	4.98
19	INT78524	Positive_regulation of Neu1	6	0.67	8.9	4.4
20	INT1701	Localization of Neu1	11	0.69	6.36	4.18
21	INT30014	Positive_regulation of HPSE	22	0.70	20.91	4.09
22	INT68978	Regulation of Positive_regulation of Hpse	6	0.45	1.88	4.02
23	INT84430	Negative_regulation of Smpd1	22	0.59	10.33	3.95
24	INT14619	Positive_regulation of Localization of NAGLU	18	0.62	7.73	3.94
25	INT26891	Gene_expression of OGG1	21	0.74	2.08	3.64
26	INT2936	Gene_expression of AGL	36	0.49	9.55	3.63
27	INT49006	Gene_expression of Neu3	13	0.08	1.22	3.63
28	INT127006	Phosphorylation of Neu3	3	0.02	0.43	3.61
29	INT61734	Regulation of HPSE	16	0.60	13.05	3.5
30	INT13321	Negative_regulation of Hpse	11	0.56	4.64	3.39
31	INT47011	Positive_regulation of Gusb	14	0.44	8.93	2.87
32	INT69621	Positive_regulation of Positive_regulation of Hpse	7	0.42	4.1	2.85
33	INT78568	Negative_regulation of Gene_expression of Glb1	4	0.30	0.78	2.84
34	INT2464	Gene_expression of AMY2A	21	0.75	13.76	2.78
35	INT171013	Regulation of SMPD1	4	0.11	4.84	2.74
36	INT96338	Gene_expression of HPSE	17	0.75	18.71	2.73
37	INT24895	Positive_regulation of LYZ	25	0.70	17.92	2.64
38	INT118887	Positive_regulation of Neu3	3	0.01	8.39	2.62
39	INT39266	Negative_regulation of Localization of Neu1	6	0.30	4.66	2.6
40	INT13414	Regulation of Regulation of Hpse	4	0.16	1.71	2.55
41	INT137616	Gene_expression of Cd38	19	0.67	9.37	2.54
42	INT171032	Positive_regulation of SMPD1	9	0.12	8.94	2.52
43	INT175797	Regulation of Gene_expression of Hpse	6	0.07	6.52	2.49
44	INT3735	Localization of Neu1	9	0.73	3.83	2.46
45	INT27217	Negative_regulation of LYZ	6	0.42	3.1	2.26
46	INT35745	Negative_regulation of AGL	29	0.50	9.16	2.03
47	INT38008	Positive_regulation of Gene_expression of NAGLU	6	0.44	6.64	2
48	INT119018	Gene_expression of TREH	22	0.65	12.44	1.95
49	INT117934	Gene_expression of Cd38	11	0.68	6.5	1.95
50	INT20388	Binding of LYZ	8	0.39	5.65	1.93
51	INT194074	Regulation of NAGLU	5	0.38	2.93	1.87
52	INT2606	Localization of NEU1	10	0.41	4.6	1.82
53	INT104672	Negative_regulation of Neu3	4	0.14	4.67	1.82
54	INT4028	Regulation of HYAL1	8	0.54	1.55	1.8
55	INT48253	Positive_regulation of AMY2A	8	0.59	3.86	1.79
56	INT86914	Positive_regulation of Smpd1	11	0.43	4.73	1.74
57	INT74707	Negative_regulation of Hpse	4	0.58	2.29	1.73
58	INT114409	Gene_expression of Lyz2	2	0.35	0	1.65
59	INT151743	Binding of Gusb	11	0.24	8.73	1.63
60	INT58931	Binding of NAGLU	11	0.34	4.47	1.63
61	INT33591	Negative_regulation of Positive_regulation of Hpse	6	0.32	3.42	1.63
62	INT129492	Gene_expression of Hpse	11	0.75	6.56	1.59
63	INT74955	Negative_regulation of HPSE	6	0.57	4.75	1.57
64	INT168860	Positive_regulation of Cd38	5	0.70	4.07	1.57
65	INT46643	Negative_regulation of HYAL1	7	0.37	4.65	1.55
66	INT39997	Negative_regulation of Gla	8	0.59	6.38	1.51
67	INT122449	Localization of SMUG1	10	0.67	7.97	1.47
68	INT168861	Positive_regulation of Gene_expression of Cd38	2	0.50	2.01	1.47
69	INT184529	Negative_regulation of SMUG1	8	0.49	7.06	1.46
70	INT184532	Binding of SMUG1	7	0.21	5.73	1.45
71	INT20233	Negative_regulation of SMPD1	8	0.51	4.19	1.4
72	INT4029	Positive_regulation of HYAL1	10	0.69	2	1.39
73	INT28787	Negative_regulation of Localization of LYZ	4	0.35	0.88	1.39
74	INT67133	Gene_expression of Gusb	14	0.75	18.57	1.37
75	INT65553	Regulation of Hpse	6	0.27	3.89	1.37
76	INT66274	Gene_expression of Ctbs	9	0.39	1.16	1.35
77	INT181856	Gene_expression of SPAM1	2	0.22	4.5	1.35
78	INT168859	Regulation of Cd38	1	0.27	0.11	1.33
79	INT1957	Localization of AMY2A	6	0.68	2.85	1.31
80	INT41805	Localization of Neu3	4	0.10	0.33	1.28
81	INT148638	Protein_catabolism of Hpse	1	0.48	1.09	1.28
82	INT26890	Negative_regulation of Gene_expression of OGG1	2	0.34	0.13	1.26
83	INT291800	Positive_regulation of NEU2	2	0.01	0.57	1.26
84	INT28788	Regulation of LYZ	5	0.42	1.8	1.24
85	INT325005	Positive_regulation of Gene_expression of SMUG1	3	0.25	0.93	1.23
86	INT117933	Positive_regulation of Gene_expression of Cd38	3	0.38	1.62	1.23
87	INT47010	Negative_regulation of Gusb	6	0.43	4.16	1.2
88	INT168864	Positive_regulation of Positive_regulation of Cd38	1	0.47	0.05	1.18
89	INT86319	Protein_catabolism of HYAL1	5	0.64	1.09	1.17
90	INT28790	Regulation of Localization of LYZ	4	0.50	0.74	1.16
91	INT31326	Binding of TREH	7	0.17	2.29	1.14
92	INT80174	Positive_regulation of Gene_expression of Neu1	23	0.37	17.82	1.12
93	INT62377	Regulation of Neu2	2	0.01	0.51	1.11
94	INT57209	Regulation of Gene_expression of Glb1	3	0.23	0.99	1.09
95	INT175794	Negative_regulation of Gene_expression of Hpse	2	0.12	1.82	1.08
96	INT223960	Positive_regulation of Transcription of AMY2A	1	0.08	4.88	1.07
97	INT223961	Transcription of AMY2A	1	0.11	4.83	1.06
98	INT127003	Binding of Neu3	7	0.02	1.57	1.05
99	INT96229	Localization of HPSE	3	0.20	2.76	1.05
100	INT185501	Localization of NEU2	4	0.02	1.08	1.04
101	INT193069	Positive_regulation of Gene_expression of CD38	4	0.15	4.06	1.01
102	INT165835	Positive_regulation of Lct	3	0.49	1.03	0.99
103	INT78569	Positive_regulation of Gene_expression of Glb1	2	0.38	0.24	0.99
104	INT171038	Positive_regulation of Localization of SMPD1	2	0.08	1.8	0.99
105	INT493	Binding of Treh	5	0.02	0.32	0.97
106	INT127005	Positive_regulation of Localization of Neu3	1	0.02	0.33	0.97
107	INT59492	Transcription of HYAL1	2	0.11	0.92	0.96
108	INT55580	Localization of Hpse	5	0.23	3.51	0.89
109	INT2607	Negative_regulation of Localization of NEU1	3	0.30	1.52	0.88
110	INT20390	Negative_regulation of Binding of LYZ	2	0.28	0.24	0.87
111	INT112760	Negative_regulation of Positive_regulation of Smpd1	2	0.38	1.45	0.84
112	INT193019	Positive_regulation of Positive_regulation of SMUG1	6	0.39	4.7	0.83
113	INT37747	Localization of Gusb	4	0.69	1.91	0.82
114	INT171030	Positive_regulation of Gene_expression of SMPD1	2	0.09	0.92	0.82
115	INT109854	Negative_regulation of Positive_regulation of Hpse	1	0.23	0	0.81
116	INT65552	Binding of Hpse	2	0.30	2.48	0.8
117	INT181858	Binding of HYAL1	8	0.16	2.22	0.79
118	INT110240	Positive_regulation of Lyz2	1	0.00	0.96	0.79
119	INT110241	Negative_regulation of Positive_regulation of Lyz2	1	0.00	0.97	0.79
120	INT131384	Binding of Mutyh	5	0.26	2.41	0.78
121	INT3732	Negative_regulation of Localization of Neu1	3	0.01	1	0.75
122	INT702	Negative_regulation of TREH	3	0.36	1.01	0.75
123	INT58866	Regulation of Neu1	3	0.08	1.13	0.75
124	INT93618	Positive_regulation of TREH	6	0.16	2.31	0.73
125	INT181867	Positive_regulation of Positive_regulation of Neu1	1	0.49	0.93	0.72
126	INT171024	Negative_regulation of Localization of SMPD1	1	0.07	1.29	0.72
127	INT72654	Regulation of Localization of Neu1	1	0.02	0.34	0.72
128	INT118886	Regulation of Positive_regulation of Neu3	1	0.01	0.61	0.72
129	INT20316	Regulation of Neu1	1	0.05	0.19	0.7
130	INT39999	Gene_expression of Gla	7	0.59	3.27	0.69
131	INT43644	Binding of Lct	1	0.38	0	0.69
132	INT164589	Negative_regulation of Positive_regulation of Glb1	1	0.43	1.16	0.67
133	INT33662	Regulation of Lyz2	1	0.04	0.08	0.66
134	INT5262	Positive_regulation of AGL	14	0.40	7.51	0.65
135	INT76902	Binding of AGL	3	0.02	2.23	0.64
136	INT164590	Positive_regulation of Glb1	2	0.69	1.77	0.64
137	INT96339	Protein_catabolism of HPSE	5	0.96	2.87	0.63
138	INT166920	Binding of Neu1	2	0.21	2.67	0.63
139	INT5261	Localization of AGL	10	0.36	3.17	0.61
140	INT317596	Positive_regulation of Gene_expression of Hpse	3	0.14	2.24	0.6
141	INT182435	Localization of OGG1	36	0.76	1.66	0.58
142	INT28876	Positive_regulation of Localization of LYZ	3	0.68	0.46	0.58
143	INT45208	Regulation of NEU1	2	0.10	3.79	0.58
144	INT96016	Negative_regulation of Lct	2	0.41	0.69	0.58
145	INT129493	Protein_catabolism of Hpse	2	0.55	2.81	0.57
146	INT71414	Binding of Neu2	1	0.02	0	0.57
147	INT23118	Positive_regulation of Gene_expression of AGL	4	0.30	1.74	0.54
148	INT171043	Negative_regulation of Gene_expression of SMPD1	2	0.08	1.15	0.53
149	INT204863	Gene_expression of Hexb	3	0.44	2.57	0.52
150	INT62184	Binding of AMY2A	3	0.41	1.06	0.52
151	INT177436	Binding of HPSE	2	0.47	1.81	0.52
152	INT215854	Positive_regulation of Gene_expression of Hexb	1	0.34	2.42	0.52
153	INT214945	Regulation of Neu3	11	0.01	1.65	0.51
154	INT67848	Localization of Neu2	5	0.07	1.17	0.51
155	INT14450	Binding of NEU1	7	0.14	5.1	0.5
156	INT165836	Positive_regulation of Positive_regulation of Lct	2	0.49	0.52	0.5
157	INT59493	Regulation of Transcription of HYAL1	1	0.00	0	0.5
158	INT165837	Negative_regulation of Positive_regulation of Lct	1	0.41	0.51	0.49
159	INT190590	Localization of Hpse	2	0.28	0.49	0.48
160	INT45878	Gene_expression of NEU1	14	0.65	7.28	0.47
161	INT102631	Localization of HYAL1	4	0.26	1.79	0.46
162	INT2610	Positive_regulation of Localization of NEU1	2	0.12	0.7	0.44
163	INT117932	Positive_regulation of Cd38	2	0.35	1.17	0.43
164	INT3689	Gene_expression of Lct	2	0.19	0.78	0.43
165	INT48326	Negative_regulation of Localization of Gusb	1	0.23	0.65	0.43
166	INT47915	Negative_regulation of NAGLU	2	0.22	0.66	0.42
167	INT134731	Localization of Cd38	4	0.70	0.87	0.41
168	INT177437	Transcription of HPSE	2	0.23	3.44	0.41
169	INT84900	Positive_regulation of Localization of Hpse	1	0.16	0.16	0.41
170	INT43645	Negative_regulation of Binding of Lct	1	0.33	0	0.41
171	INT235063	Positive_regulation of Gene_expression of Gla	2	0.04	0.81	0.39
172	INT184203	Regulation of SPAM1	2	0.17	1.43	0.39
173	INT184197	Localization of SPAM1	1	0.21	1.49	0.39
174	INT319548	Positive_regulation of Localization of Hpse	1	0.17	0.08	0.38
175	INT129302	Positive_regulation of Gene_expression of TREH	4	0.49	1.28	0.37
176	INT9778	Regulation of Glb1	4	0.19	1.48	0.37
177	INT342278	Localization of Lyz2	2	0.03	0.37	0.37
178	INT30370	Negative_regulation of AMY2A	7	0.49	3.36	0.36
179	INT47175	Negative_regulation of Negative_regulation of AGL	4	0.24	1.19	0.36
180	INT22236	Negative_regulation of CD38	2	0.41	0.1	0.36
181	INT129494	Regulation of Gene_expression of Hpse	2	0.23	1.36	0.36
182	INT129495	Negative_regulation of Gene_expression of Hpse	1	0.36	0.52	0.36
183	INT350224	Regulation of NEU2	1	0.00	0.25	0.35
184	INT15031	Positive_regulation of Treh	1	0.03	0	0.35
185	INT74954	Positive_regulation of Positive_regulation of HPSE	2	0.40	0.45	0.34
186	INT79189	Transcription of Glb1	1	0.29	0	0.34
187	INT55784	Negative_regulation of Neu1	4	0.24	1.93	0.33
188	INT32138	Positive_regulation of Neu2	3	0.02	0.86	0.33
189	INT55582	Positive_regulation of Negative_regulation of Hpse	2	0.13	0.56	0.32
190	INT177439	Negative_regulation of Positive_regulation of HPSE	1	0.21	1.48	0.32
191	INT65389	Negative_regulation of Treh	1	0.02	0.15	0.32
192	INT184205	Binding of SPAM1	3	0.09	0.86	0.31
193	INT350226	Negative_regulation of Positive_regulation of NEU2	1	0.00	0.14	0.31
194	INT173329	Protein_catabolism of SMPD1	1	0.13	0	0.31
195	INT264860	Binding of Cd38	1	0.39	2.36	0.31
196	INT214579	Positive_regulation of CD38	4	0.24	1.22	0.3
197	INT181855	Negative_regulation of Gene_expression of HYAL1	1	0.10	0.59	0.3
198	INT318060	Phosphorylation of SMUG1	4	0.69	2.39	0.29
199	INT181854	Positive_regulation of Gene_expression of HYAL1	2	0.14	0.58	0.29
200	INT83288	Negative_regulation of NEU4	12	0.51	3.58	0.28