GO:0016818

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Name hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
Categary Function
Go Slim No
Go Link GO:0016818
Unique Molecular Interactions 26
Total Molecular Interactions 37
Total Single Events 153
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides. They are ordered first by their pain relevance and then by number of times they were reported for hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT81580 Cyp3a23/3a1 Positive_regulation of Nudt14 1 0.01 0 1.08
2 INT81581 Plec Positive_regulation of Nudt14 1 0.01 0 1.07
3 INT75823 Penk Positive_regulation of Gene_expression of Ddx5 1 0.03 0 0.92
4 INT75825 Ddx5 Positive_regulation of Gene_expression of Penk 1 0.03 0 0.92
5 INT122823 ERCC2 Regulation of Negative_regulation of OPRM1 1 0.23 0.17 0.63
6 INT142947 Binding of ERCC2 and OPRM1 1 0.05 0.3 0.32
7 INT239324 Nr1h2 Positive_regulation of Hltf 1 0.04 0.78 0.29
8 INT239329 Nr1h2 Positive_regulation of Gene_expression of Hltf 1 0.04 0.84 0.29
9 INT103557 Binding of ERCC2 and TP53 1 0.40 1 0.13
10 INT267152 Binding of LEP and DDX12P 1 0.00 0.69 0.05
11 INT348038 Binding of Fos and Hltf 1 0.01 0.45 0.03
12 INT234180 Binding of BRCA1 and BRIP1 1 0.33 1.37 0
13 INT97441 Positive_regulation of Binding of Hltf and Hemgn 1 0.00 0 0
14 INT290022 Binding of PPARG and DDX12P 1 0.00 1.77 0
15 INT273949 Binding of Crem and Smarca4 1 0.01 0 0
16 INT97440 Binding of Hltf and Hemgn 1 0.00 0 0
17 INT351982 Smarca4 Positive_regulation of Stk11 1 0.05 0.58 0
18 INT149429 ERCC2 Negative_regulation of Localization of IL8 1 0.05 0.38 0
19 INT227840 Binding of ERCC2 and ERCC6 1 0.11 0.66 0
20 INT149431 ERCC2 Negative_regulation of Localization of Il6 1 0.14 0.2 0
21 INT227831 Binding of ERCC2 and PGBD3 1 0.07 0.23 0
22 INT248387 CHD5 Regulation of Gene_expression of TP53 1 0.20 0.83 0
23 INT149432 ERCC2 Regulation of Localization of Il6 1 0.15 1.06 0
24 INT286186 Binding of Blm and Fig4 1 0.09 0.34 0
25 INT149428 ERCC2 Regulation of Localization of IL8 1 0.05 0.53 0
26 INT315814 Tst Positive_regulation of Localization of RTEL1 1 0.02 2.19 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides. They are ordered first by their pain relevance and then by number of times they were reported in hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT103899 Gene_expression of ERCC2 14 0.65 7.85 5.49
2 INT48661 Gene_expression of Ddx5 7 0.07 0.15 4.04
3 INT48662 Negative_regulation of Gene_expression of Ddx5 5 0.04 0.07 2.41
4 INT66391 Negative_regulation of Ddx5 2 0.04 0 2.17
5 INT103900 Positive_regulation of ERCC2 7 0.58 3.47 1.78
6 INT8538 Positive_regulation of Ddx5 2 0.19 0 1.73
7 INT70404 Positive_regulation of Gene_expression of Ddx5 2 0.02 0 1.62
8 INT142950 Protein_catabolism of ERCC2 2 0.25 1.45 1.14
9 INT231961 Gene_expression of Hltf 2 0.28 2.01 1.11
10 INT82969 Positive_regulation of Hltf 2 0.02 0.28 1.03
11 INT231962 Positive_regulation of Gene_expression of Hltf 1 0.25 1.19 0.83
12 INT117083 Localization of RTEL1 5 0.60 9.1 0.8
13 INT82968 Phosphorylation of Hltf 2 0.31 0.07 0.74
14 INT38197 Localization of Nudt14 1 0.17 0 0.72
15 INT134070 Binding of ERCC2 3 0.27 0.76 0.51
16 INT186882 Gene_expression of RTEL1 13 0.27 13.45 0.49
17 INT148087 Positive_regulation of RTEL1 9 0.17 5.13 0.41
18 INT226818 Negative_regulation of RTEL1 1 0.06 1.17 0.41
19 INT103901 Regulation of ERCC2 1 0.23 0.51 0.4
20 INT267166 Binding of DDX12P 1 0.01 3.34 0.18
21 INT41670 Positive_regulation of Nudt14 3 0.11 0.91 0.16
22 INT286183 Regulation of Blm 1 0.36 1.3 0.09
23 INT286184 Gene_expression of Blm 1 0.39 2.16 0.09
24 INT200136 Negative_regulation of ERCC2 1 0.37 1.91 0.07
25 INT260908 Positive_regulation of Smarca4 2 0.21 0.53 0.03
26 INT315806 Phosphorylation of RTEL1 1 0.04 0.68 0.03
27 INT291906 Positive_regulation of Negative_regulation of ERCC2 1 0.40 0 0.03
28 INT186878 Binding of RTEL1 7 0.12 4.75 0
29 INT248395 Regulation of CHD5 1 0.24 0.96 0
30 INT315808 Positive_regulation of Protein_catabolism of RTEL1 1 0.03 0.98 0
31 INT315810 Positive_regulation of Gene_expression of RTEL1 1 0.03 1.77 0
32 INT248392 Positive_regulation of Gene_expression of CHD5 1 0.45 0.87 0
33 INT186880 Regulation of RTEL1 1 0.11 0.54 0
34 INT315811 Negative_regulation of Binding of RTEL1 1 0.02 0.86 0
35 INT248393 Binding of CHD5 1 0.33 0.22 0
36 INT248394 Gene_expression of CHD5 1 0.70 2.3 0
37 INT315970 Regulation of Gene_expression of RTEL1 1 0.03 1.35 0
38 INT186879 Positive_regulation of Positive_regulation of RTEL1 1 0.12 0.29 0
39 INT234190 Gene_expression of BRIP1 1 0.55 0.6 0
40 INT149430 Localization of ERCC2 1 0.43 0.76 0
41 INT315807 Protein_catabolism of RTEL1 1 0.05 0.84 0
42 INT286182 Positive_regulation of Gene_expression of Blm 1 0.29 0.53 0
43 INT260913 Negative_regulation of Smarca4 1 0.18 0.29 0
44 INT248397 Positive_regulation of CHD5 1 0.39 0.24 0
45 INT273916 Binding of Smarca4 1 0.01 0 0
46 INT322459 Binding of Hltf 1 0.01 0.36 0
47 INT315809 Regulation of Protein_catabolism of RTEL1 1 0.03 0.97 0
48 INT315971 Transcription of RTEL1 1 0.04 1.28 0
49 INT290039 Gene_expression of DDX12P 1 0.00 1.41 0
50 INT248396 Negative_regulation of CHD5 1 0.39 0.93 0
51 INT352864 Regulation of BRIP1 1 0.51 0.13 0
52 INT322447 Regulation of Hltf 1 0.01 0.36 0
53 INT186881 Positive_regulation of Binding of RTEL1 1 0.12 0.5 0
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