GO:0021861

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Latest revision as of 11:45, 23 January 2013

Name forebrain radial glial cell differentiation
Categary Process
Go Slim No
Go Link GO:0021861
Unique Molecular Interactions 38
Total Molecular Interactions 49
Total Single Events 168
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

[edit] Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for forebrain radial glial cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for forebrain radial glial cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85
2 INT278690 LEF1 Negative_regulation of Gene_expression of IK 1 0.00 0.66 0.83
3 INT278697 LEF1 Negative_regulation of STAT6 1 0.00 0.44 0.78
4 INT314203 Nos2 Positive_regulation of Gli3 1 0.19 1.27 0.73
5 INT68561 Binding of Gli3 and Ust 1 0.01 0.68 0.68
6 INT297545 Pou3f3 Regulation of Hes1 1 0.05 0.41 0.2
7 INT297548 Neurod1 Regulation of Hes1 1 0.05 0.2 0.1
8 INT289101 Binding of KCNA1 and LEF1 1 0.00 2.58 0.03
9 INT337402 LEF1 Positive_regulation of E2F1 1 0.11 0 0
10 INT264735 Binding of Hes1 and Mir199b 1 0.08 0.93 0
11 INT302321 Negative_regulation of Binding of Lrp6 and SOST 1 0.16 0.26 0
12 INT264738 Mir199b Regulation of Gene_expression of Hes1 1 0.08 0.89 0
13 INT183648 Binding of Lef1 and Ctnnd2 1 0.07 1.05 0
14 INT337415 Negative_regulation of MIR203 Positive_regulation of Positive_regulation of LEF1 1 0.03 0.25 0
15 INT337405 MIR203 Regulation of LEF1 1 0.02 0.31 0
16 INT264736 Hes1 Regulation of Notch2 1 0.20 0.13 0
17 INT337411 Negative_regulation of MIR203 Positive_regulation of Gene_expression of LEF1 1 0.04 0.25 0
18 INT197316 Hes1 Regulation of Atoh1 1 0.01 0.14 0
19 INT302320 Binding of Lrp6 and SOST 1 0.18 0.26 0
20 INT289102 KCNA1 Negative_regulation of Gene_expression of LEF1 1 0.00 0.44 0
21 INT289098 KCNA1 Regulation of LEF1 1 0.00 0.67 0
22 INT335887 Akt1 Regulation of Lrp6 1 0.06 0.15 0
23 INT197304 Ahr Regulation of Hes1 1 0.06 0.17 0
24 INT335883 Binding of Lrp6 and Wnt5a 1 0.27 0.08 0
25 INT264731 Gene_expression of Hes1 Negative_regulation of Positive_regulation of Musd1 1 0.00 0.18 0
26 INT337417 MIR203 Negative_regulation of LEF1 1 0.04 0.57 0
27 INT220822 Binding of Myc and LEF1 1 0.26 0.08 0
28 INT197315 Hes5 Regulation of Atoh1 1 0.00 0.14 0
29 INT220766 Binding of MAX and LEF1 1 0.40 0.08 0
30 INT197314 Hes5 Regulation of Ascl1 1 0.00 0.14 0
31 INT264729 Mir199b Regulation of Hes1 1 0.05 0.25 0
32 INT197310 Hes1 Regulation of Ascl1 1 0.01 0.14 0
33 INT264725 Binding of Hes1 and Notch1 1 0.03 0.84 0
34 INT264734 Mir199b Negative_regulation of Negative_regulation of Hes1 1 0.07 0.1 0
35 INT289100 KCNA1 Regulation of Gene_expression of LEF1 1 0.00 0.68 0
36 INT264739 Mir199b Negative_regulation of Gene_expression of Hes1 1 0.07 0.82 0
37 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0
38 INT264733 Hes1 Regulation of Mir199b 1 0.05 0.43 0

[edit] Single Events

The table below shows the top 100 pain related interactions that have been reported for forebrain radial glial cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in forebrain radial glial cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT68559 Negative_regulation of Gli3 5 0.37 4.56 4.93
2 INT126581 Positive_regulation of Gli3 6 0.35 1.59 2.48
3 INT126374 Gene_expression of Gli3 6 0.77 3.67 2.02
4 INT278715 Gene_expression of LEF1 10 0.33 5.43 1.54
5 INT278727 Negative_regulation of Gene_expression of LEF1 3 0.11 1.59 1.47
6 INT140245 Binding of Gli3 3 0.36 2.65 1.46
7 INT152951 Negative_regulation of LEF1 5 0.41 3.22 1.31
8 INT108519 Binding of Lrp6 8 0.44 1.47 1.19
9 INT278710 Phosphorylation of LEF1 1 0.05 0.76 0.82
10 INT68560 Regulation of Gli3 3 0.18 1.51 0.68
11 INT264709 Gene_expression of Hes1 24 0.76 7.04 0.63
12 INT135062 Transcription of Gli3 1 0.05 0 0.52
13 INT111230 Transcription of LEF1 3 0.30 1.72 0.33
14 INT335875 Regulation of Lrp6 1 0.57 0.43 0.27
15 INT135061 Protein_catabolism of Gli3 1 0.04 0 0.25
16 INT135060 Negative_regulation of Transcription of Gli3 1 0.03 0 0.19
17 INT264701 Negative_regulation of Gene_expression of Hes1 1 0.42 0.73 0.18
18 INT335861 Localization of Lrp6 1 0.69 0.54 0.17
19 INT270451 Localization of Gli3 1 0.26 0.63 0.11
20 INT135063 Regulation of Gene_expression of Gli3 1 0.04 0 0.09
21 INT126375 Negative_regulation of Gene_expression of Gli3 1 0.58 0.79 0.08
22 INT298251 Gene_expression of Hes5 2 0.45 0.39 0.06
23 INT335865 Positive_regulation of Phosphorylation of Lrp6 1 0.64 0.46 0.05
24 INT335862 Phosphorylation of Lrp6 1 0.76 0.37 0.05
25 INT220802 Binding of LEF1 7 0.36 3.86 0.04
26 INT289116 Positive_regulation of Localization of LEF1 2 0.22 1.19 0.04
27 INT289110 Localization of LEF1 2 0.32 1.19 0.04
28 INT264717 Negative_regulation of Hes1 7 0.42 0.77 0.03
29 INT264704 Regulation of Hes1 4 0.44 1.03 0.03
30 INT264702 Positive_regulation of Gene_expression of Hes1 1 0.68 1.39 0.03
31 INT264719 Regulation of Gene_expression of Hes1 2 0.28 0.12 0
32 INT289127 Positive_regulation of LEF1 2 0.22 0.76 0
33 INT264708 Transcription of Hes1 1 0.67 0.83 0
34 INT335872 Positive_regulation of Gene_expression of Lrp6 1 0.46 0.18 0
35 INT337456 Positive_regulation of Binding of LEF1 1 0.22 0 0
36 INT234916 Gene_expression of Lef1 1 0.04 0.25 0
37 INT264705 Binding of Hes1 1 0.35 0.07 0
38 INT289129 Positive_regulation of Gene_expression of LEF1 1 0.13 0.76 0
39 INT298236 Localization of Hes5 1 0.51 0.39 0
40 INT264706 Positive_regulation of Hes1 1 0.40 0.14 0
41 INT337461 Positive_regulation of Transcription of LEF1 1 0.22 0.26 0
42 INT289108 Negative_regulation of Transcription of LEF1 1 0.11 0.32 0
43 INT347117 Negative_regulation of Binding of Lrp6 1 0.28 0.5 0
44 INT335866 Regulation of Transcription of Lrp6 1 0.42 0.25 0
45 INT220775 Binding of Lef1 1 0.20 0.06 0
46 INT335881 Gene_expression of Lrp6 1 0.62 0.09 0
47 INT289124 Negative_regulation of Positive_regulation of LEF1 1 0.11 0.34 0
48 INT335873 Transcription of Lrp6 1 0.64 0.25 0
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