GO:0030157

Name pancreatic juice secretion Categary Process Go Slim No Go Link GO:0030157

Unique Molecular Interactions 113 Total Molecular Interactions 140 Total Single Events 1302 Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for pancreatic juice secretion. They are ordered first by their pain relevance and then by number of times they were reported for pancreatic juice secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT138961	Dbi Positive_regulation of Chkb	1	0.00	3.05	3.99
2	INT138959	Dbi Positive_regulation of Penk	1	0.01	3.05	3.99
3	INT140011	Avp Positive_regulation of Dbi	2	0.07	0.93	3.61
4	INT37162	Binding of Calca and Cckar	1	0.04	0.55	3.01
5	INT138962	Dbi Positive_regulation of Pomc	1	0.00	1.53	2
6	INT138960	Dbi Positive_regulation of Avp	1	0.02	1.53	2
7	INT138958	Dbi Positive_regulation of Positive_regulation of Avp	1	0.02	1.53	2
8	INT140013	Avp Positive_regulation of Gene_expression of Dbi	1	0.07	0.85	1.52
9	INT140012	Avp Negative_regulation of Dbi	1	0.06	0.8	1.44
10	INT219686	Binding of CEL and COPD	1	0.12	11.35	1.26
11	INT76199	CASP1 Positive_regulation of CEL	1	0.06	0.32	1.14
12	INT41093	Binding of Dbi and Nil	1	0.00	0	0.93
13	INT161769	Cck Regulation of Cckar	1	0.27	0.53	0.92
14	INT55204	Prl Positive_regulation of Localization of Dbi	1	0.02	0	0.91
15	INT122191	Binding of Crh and Ucn	4	0.36	0.79	0.82
16	INT99578	Binding of CEL and Kit	1	0.04	1.07	0.81
17	INT87646	Dbi Regulation of Olfr1507	1	0.00	0.69	0.72
18	INT95148	CEL Regulation of IL1B	1	0.24	0.88	0.7
19	INT122190	Binding of Crhr1 and Ucn	4	0.49	0.65	0.67
20	INT2401	SCT Positive_regulation of SGCA	1	0.00	0	0.62
21	INT26648	Binding of CEL and HP	1	0.04	0	0.58
22	INT98815	Binding of Crhr2 and Ucn	3	0.32	0.5	0.56
23	INT32479	Gh1 Negative_regulation of Dbi	1	0.01	0	0.51
24	INT160444	Tpsab1 Positive_regulation of Gene_expression of CEL	1	0.48	0.96	0.48
25	INT34982	Trh Regulation of Dbi	1	0.12	0	0.47
26	INT34984	Negative_regulation of Trh Regulation of Dbi	1	0.19	0	0.47
27	INT34983	Gene_expression of Dbi Positive_regulation of Localization of Trh	1	0.22	0	0.42
28	INT34981	Gene_expression of Dbi Positive_regulation of Localization of Prl	1	0.23	0	0.41
29	INT219683	Binding of CEL and GOPC	1	0.04	3.11	0.38
30	INT63970	Binding of TRPV1 and Copa	1	0.00	0	0.37
31	INT164371	Dbi Regulation of Pomc	1	0.19	0.17	0.35
32	INT88904	Binding of SCT and Hcrt	1	0.07	0	0.31
33	INT88903	Regulation of Binding of SCT and Hcrt	1	0.06	0	0.31
34	INT168948	Binding of CCK and CCKAR	1	0.23	0	0.3
35	INT260433	Dbi Positive_regulation of Cd8a	1	0.00	0.13	0.3
36	INT35858	PRSS1 Regulation of Positive_regulation of SCT	1	0.17	0.18	0.3
37	INT17162	Binding of CEL and Lhb	1	0.06	0.38	0.3
38	INT139778	Binding of AQP1 and GBE1	1	0.00	0.22	0.3
39	INT118239	Binding of CCKAR and CYP2B6	1	0.32	0.19	0.29
40	INT98816	Crhr2 Positive_regulation of Negative_regulation of Ucn	1	0.33	0.09	0.28
41	INT233785	Binding of SCT and VIPR1	1	0.08	0	0.27
42	INT233784	Binding of GCG and SCT	1	0.06	0	0.27
43	INT233781	Binding of PTH1R and SCT	1	0.18	0	0.27
44	INT233786	Binding of CALCR and SCT	1	0.05	0	0.27
45	INT233780	Binding of ADCYAP1 and SCT	1	0.16	0	0.27
46	INT233782	Binding of PTHLH and SCT	1	0.06	0	0.27
47	INT233783	Binding of SCT and VIPR2	1	0.13	0	0.27
48	INT82194	Dbi Regulation of Oprd1	1	0.12	0.07	0.26
49	INT60360	SCT Regulation of NTS	1	0.13	0	0.24
50	INT43532	Dbi Negative_regulation of Localization of LH	1	0.15	0.75	0.23
51	INT60361	SCT Regulation of CCK	1	0.19	0	0.23
52	INT58305	AQP1 Regulation of Localization of TNF	1	0.10	0.16	0.22
53	INT58303	AQP1 Regulation of Gene_expression of IL1B	1	0.10	0.16	0.22
54	INT35966	SCT Regulation of Localization of LIPF	1	0.32	0.24	0.22
55	INT35472	Dbi Regulation of Gnrh1	1	0.06	0.17	0.22
56	INT35967	SCT Positive_regulation of Localization of LIPF	1	0.33	0.24	0.22
57	INT106993	CEL Positive_regulation of NR1I2	1	0.39	0.39	0.22
58	INT35468	Dbi Regulation of Prl	1	0.05	0.17	0.22
59	INT143394	Ucn Regulation of Crh	1	0.44	0.19	0.2
60	INT46285	SCT Positive_regulation of PRSS1	1	0.16	0.1	0.19
61	INT35471	Dbi Negative_regulation of Localization of Gnrh1	1	0.05	0.14	0.19
62	INT46286	SCT Positive_regulation of CTRC	1	0.24	0.1	0.19
63	INT348059	Dbi Negative_regulation of Binding of Mpo	1	0.08	0.43	0.19
64	INT49057	Positive_regulation of CEL Positive_regulation of Localization of LTC4S	1	0.41	0.28	0.18
65	INT94355	NOVA2 Positive_regulation of Dbi	1	0.00	0.15	0.18
66	INT42521	Pomc Regulation of Dbi	1	0.06	0	0.17
67	INT32665	Pomc Negative_regulation of Dbi	1	0.06	0	0.17
68	INT5520	Negative_regulation of Dbi Negative_regulation of Gene_expression of Crh	1	0.21	0.44	0.16
69	INT5517	Negative_regulation of Dbi Negative_regulation of Crh	1	0.27	0.44	0.16
70	INT355410	Ins1 Regulation of Gene_expression of Dbi	1	0.07	0.57	0.16
71	INT35860	PRSS1 Regulation of Localization of SCT	1	0.10	0.08	0.16
72	INT231838	Pcdh8 Regulation of Cel	1	0.00	0.39	0.15
73	INT85816	Binding of CEL and TTR	1	0.39	0.77	0.14
74	INT231846	Pcdh8 Negative_regulation of Positive_regulation of Cel	1	0.00	0.91	0.14
75	INT355408	Ins1 Regulation of Dbi	1	0.07	0.58	0.14
76	INT92671	Binding of CEL and HLA-B	1	0.38	0.19	0.1
77	INT246535	Binding of Cel and Mag	1	0.01	7.26	0.1
78	INT43530	Dbi Negative_regulation of LH	1	0.18	0.3	0.1
79	INT5519	Dbi Negative_regulation of Crh	1	0.31	0.28	0.1
80	INT32030	Binding of CEL and ERLEC1	1	0.08	0.42	0.1
81	INT43529	Dbi Negative_regulation of Gene_expression of LH	1	0.13	0.3	0.1
82	INT139250	CCKAR Positive_regulation of Localization of POMC	1	0.35	0.61	0.09
83	INT41574	POMC Regulation of CCKAR	1	0.00	0	0.09
84	INT94353	Crh Negative_regulation of Positive_regulation of Dbi	1	0.03	0.14	0.08
85	INT205033	Ucn Positive_regulation of Crhr2	1	0.22	0.15	0.08
86	INT94354	Crh Negative_regulation of Dbi	1	0.03	0.14	0.08
87	INT43528	Dbi Regulation of Localization of LH	1	0.09	0.21	0.07
88	INT45623	Binding of ALB and SCT	1	0.10	0.12	0.06
89	INT222544	Binding of Ucn and Crh	1	0.02	0	0.05
90	INT231834	Trip12 Positive_regulation of Positive_regulation of Cel	1	0.00	0.75	0.05
91	INT133047	TNF Positive_regulation of Gene_expression of CEL	1	0.47	0.61	0.05
92	INT177350	Binding of CEL and PLA2G2A	1	0.06	0.08	0.04
93	INT222417	Ucn Positive_regulation of Localization of Pomc	1	0.01	0	0.04
94	INT352624	Trp53 Negative_regulation of CEL	1	0.01	1.01	0.03
95	INT222469	Binding of Ucn and Crhr2	1	0.00	0	0.03
96	INT280601	Binding of HIVEP1 and Dbi	1	0.00	1.57	0.03
97	INT177352	Binding of CEL and PTN	1	0.01	0	0.03
98	INT352625	Trp53 Regulation of CEL	1	0.00	0.71	0
99	INT304135	Binding of CEL and Positive_regulation of CASP8	1	0.00	0.52	0
100	INT262746	Binding of Dbi and RN7SL2	1	0.00	0	0
101	INT79900	NFE2L2 Positive_regulation of Gene_expression of AQP1	1	0.03	0	0
102	INT262498	Binding of Aqp1 and Cav1	1	0.03	0.56	0
103	INT44885	Binding of CEL and MET	1	0.39	0.15	0
104	INT246536	Mag Regulation of Gene_expression of Cel	1	0.01	1.28	0
105	INT169485	Dbi Regulation of Prkca	1	0.02	0.08	0
106	INT35470	Binding of Prl and Dbi	1	0.05	0.17	0
107	INT98626	Aqp1 Positive_regulation of Aqp4	1	0.52	0	0
108	INT169484	Dbi Regulation of Oprk1	1	0.01	0.07	0
109	INT285042	Dbi Regulation of Gene_expression of Rho	1	0.01	0	0
110	INT262747	Binding of CHN1 and Dbi	1	0.01	0	0
111	INT68256	Binding of GH1 and SCT	1	0.04	0.54	0
112	INT4817	Binding of CALCA and SCT	1	0.01	0	0
113	INT183740	Dbi Negative_regulation of A230066D03Rik	1	0.00	0.69	0

Single Events

The table below shows the top 100 pain related interactions that have been reported for pancreatic juice secretion. They are ordered first by their pain relevance and then by number of times they were reported in pancreatic juice secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT20345	Gene_expression of Dbi	136	0.78	56.41	46.2
2	INT5989	Positive_regulation of Dbi	79	0.49	24.38	32.56
3	INT5988	Localization of Dbi	74	0.81	17.52	24.09
4	INT4465	Gene_expression of CEL	116	0.77	98.35	23.58
5	INT11762	Regulation of Dbi	40	0.62	7.83	14.48
6	INT36263	Positive_regulation of CEL	53	0.69	34.88	12.87
7	INT5512	Negative_regulation of Dbi	32	0.36	7.33	9.1
8	INT2241	Negative_regulation of CEL	56	0.58	29.32	8.83
9	INT30638	Positive_regulation of Gene_expression of Dbi	17	0.69	4.63	8.28
10	INT20343	Positive_regulation of Localization of Dbi	21	0.63	5.01	6.61
11	INT19779	Binding of Dbi	41	0.36	8.8	5.87
12	INT2132	Localization of SCT	29	0.81	8.39	5.43
13	INT23725	Gene_expression of CCKAR	14	0.55	0.14	5.3
14	INT23245	Positive_regulation of Gene_expression of CEL	19	0.69	14.81	4.92
15	INT79902	Gene_expression of AQP1	33	0.78	24.72	4.55
16	INT18995	Binding of CEL	23	0.47	14.46	4.5
17	INT11708	Regulation of SCT	12	0.44	2.29	4.07
18	INT4464	Localization of CEL	21	0.80	8.09	3.88
19	INT27642	Regulation of Gene_expression of Dbi	10	0.44	2.55	3.66
20	INT2886	Gene_expression of SCT	13	0.78	4.55	3.57
21	INT23728	Negative_regulation of CCKAR	6	0.42	0.48	3.53
22	INT175442	Gene_expression of Cel	22	0.34	21.36	3.33
23	INT20344	Regulation of Localization of Dbi	8	0.49	1.97	3.31
24	INT53813	Positive_regulation of Cel	20	0.58	19.39	3.05
25	INT4820	Negative_regulation of SCT	7	0.43	4.06	3.01
26	INT85947	Regulation of Cckar	2	0.36	2.4	2.86
27	INT23534	Regulation of CCKAR	8	0.32	0.17	2.56
28	INT40505	Positive_regulation of CCKAR	3	0.40	0	2.42
29	INT2611	Negative_regulation of AQP1	17	0.39	10.04	2.15
30	INT3179	Positive_regulation of SCT	15	0.50	4.79	1.98
31	INT2409	Binding of SCT	7	0.48	2.69	1.94
32	INT47628	Regulation of CEL	9	0.60	4.5	1.85
33	INT30373	Localization of CCKAR	5	0.68	0.17	1.79
34	INT32543	Negative_regulation of Gene_expression of Dbi	6	0.42	2.46	1.67
35	INT80162	Localization of Ucn	6	0.80	0.6	1.66
36	INT75694	Regulation of Gene_expression of CEL	9	0.60	6.08	1.53
37	INT54775	Binding of Cckar	1	0.34	0	1.43
38	INT211054	Positive_regulation of AQP1	3	0.33	4.53	1.41
39	INT168954	Binding of CCKAR	1	0.28	0	1.36
40	INT73553	Gene_expression of Aqp1	23	0.67	4.65	1.34
41	INT23727	Positive_regulation of Gene_expression of CCKAR	4	0.31	0	1.34
42	INT11415	Negative_regulation of Cel	5	0.38	5.67	1.29
43	INT2741	Regulation of Localization of SCT	3	0.26	0.16	1.2
44	INT32541	Positive_regulation of Positive_regulation of Dbi	2	0.39	0.5	1.14
45	INT123554	Transcription of Dbi	5	0.72	1.13	1.13
46	INT166889	Positive_regulation of Gene_expression of AQP1	10	0.70	6.43	0.99
47	INT30942	Regulation of Regulation of Dbi	2	0.07	0.12	0.98
48	INT183362	Regulation of AQP1	3	0.23	1.49	0.92
49	INT2131	Positive_regulation of Localization of SCT	6	0.47	2.01	0.88
50	INT80159	Gene_expression of Ucn	3	0.67	0.47	0.82
51	INT23726	Positive_regulation of Negative_regulation of CCKAR	1	0.08	0	0.82
52	INT322101	Localization of Cel	2	0.29	1.11	0.76
53	INT23953	Gene_expression of Cckar	3	0.65	0.2	0.74
54	INT81622	Positive_regulation of Positive_regulation of CEL	4	0.49	3.94	0.73
55	INT76127	Transcription of CEL	5	0.71	2.02	0.7
56	INT175450	Positive_regulation of Gene_expression of Cel	4	0.25	2.69	0.68
57	INT108328	Negative_regulation of Gene_expression of CEL	6	0.57	2.56	0.63
58	INT5504	Negative_regulation of Negative_regulation of Dbi	2	0.25	0.43	0.63
59	INT32542	Negative_regulation of Positive_regulation of Dbi	2	0.17	0	0.63
60	INT168965	Negative_regulation of Binding of CCKAR	1	0.22	0	0.63
61	INT168966	Positive_regulation of Localization of CCKAR	1	0.29	0	0.62
62	INT25006	Negative_regulation of Gene_expression of CCKAR	1	0.30	0	0.62
63	INT183163	Positive_regulation of Positive_regulation of Cel	9	0.31	11.55	0.58
64	INT169489	Positive_regulation of Localization of CEL	1	0.45	0.34	0.58
65	INT80160	Negative_regulation of Ucn	2	0.58	0.29	0.56
66	INT231823	Negative_regulation of Positive_regulation of Cel	2	0.17	2.34	0.56
67	INT21882	Negative_regulation of Localization of Dbi	3	0.45	0.28	0.55
68	INT98814	Negative_regulation of Ucn	2	0.27	0.14	0.55
69	INT139780	Binding of AQP1	7	0.32	4.62	0.54
70	INT62101	Protein_catabolism of CCKAR	1	0.01	0	0.54
71	INT122186	Binding of Ucn	2	0.23	0.37	0.53
72	INT80163	Positive_regulation of Gene_expression of Ucn	1	0.50	0.41	0.52
73	INT39113	Negative_regulation of Cckar	2	0.41	0.28	0.5
74	INT185621	Positive_regulation of Gene_expression of SCT	4	0.14	2.14	0.49
75	INT19592	Localization of AQP1	4	0.81	1.09	0.44
76	INT327786	Negative_regulation of Gene_expression of AQP1	3	0.29	4.21	0.44
77	INT2740	Negative_regulation of Localization of SCT	3	0.42	0.42	0.44
78	INT53811	Regulation of Cel	4	0.23	2.1	0.43
79	INT123831	Regulation of Ucn	2	0.42	0	0.42
80	INT228731	Negative_regulation of Gene_expression of Cel	2	0.17	1.12	0.41
81	INT60601	Negative_regulation of Negative_regulation of CEL	1	0.41	0.34	0.4
82	INT65090	Negative_regulation of Positive_regulation of SCT	1	0.30	0	0.4
83	INT42288	Negative_regulation of Binding of Dbi	1	0.13	0	0.37
84	INT135069	Regulation of Localization of CEL	1	0.44	0	0.34
85	INT352167	Negative_regulation of Positive_regulation of CEL	1	0.04	1.07	0.31
86	INT59862	Phosphorylation of CEL	2	0.70	0.53	0.3
87	INT53814	Regulation of Positive_regulation of Cel	2	0.23	0.45	0.29
88	INT281746	Negative_regulation of Localization of CEL	1	0.03	0.6	0.29
89	INT280795	Positive_regulation of Ucn	1	0.31	0.06	0.27
90	INT63967	Negative_regulation of Copa	1	0.02	0	0.26
91	INT122676	Positive_regulation of Ucn	1	0.43	0.92	0.26
92	INT143391	Gene_expression of Ucn	1	0.67	0.2	0.26
93	INT175459	Binding of Cel	2	0.11	6.62	0.24
94	INT16158	Protein_catabolism of CEL	1	0.64	0	0.24
95	INT30371	Regulation of Localization of CCKAR	1	0.18	0.17	0.22
96	INT202425	Negative_regulation of Transcription of CEL	1	0.03	0.49	0.21
97	INT10042	Protein_catabolism of Cckar	1	0.08	0	0.18
98	INT19780	Protein_catabolism of Dbi	3	0.29	0.43	0.17
99	INT215814	Negative_regulation of Gene_expression of Aqp1	2	0.31	0.25	0.17
100	INT76880	Localization of Cckar	2	0.07	0.08	0.17
101	INT98625	Regulation of Aqp1	1	0.27	0.1	0.17
102	INT175454	Positive_regulation of Binding of Cel	1	0.15	0.92	0.14
103	INT215820	Negative_regulation of Aqp1	3	0.23	0.83	0.1
104	INT159343	Positive_regulation of Localization of AQP1	1	0.11	0	0.1
105	INT131055	Positive_regulation of Cckar	1	0.36	0	0.09
106	INT280766	Localization of Ucn	1	0.46	0	0.07
107	INT262510	Regulation of Gene_expression of Aqp1	1	0.33	1.18	0.07
108	INT257457	Positive_regulation of Positive_regulation of SCT	1	0.20	1.66	0.07
109	INT222594	Binding of Ucn	1	0.06	0	0.03
110	INT123553	Positive_regulation of Transcription of Dbi	2	0.69	0.52	0
111	INT262504	Positive_regulation of Aqp1	1	0.25	0.43	0
112	INT238790	Regulation of Gene_expression of Cel	1	0.07	1.27	0
113	INT286264	Positive_regulation of Negative_regulation of AQP1	1	0.01	0.79	0
114	INT262513	Negative_regulation of Binding of Aqp1	1	0.23	0.64	0
115	INT19781	Negative_regulation of Protein_catabolism of Dbi	1	0.18	0	0
116	INT262514	Binding of Aqp1	1	0.20	0.64	0
117	INT352610	Regulation of Regulation of CEL	1	0.00	0.55	0
118	INT97442	Positive_regulation of Binding of CEL	1	0.67	0	0
119	INT299193	Transcription of Aqp1	1	0.56	0.62	0
120	INT262511	Positive_regulation of Gene_expression of Aqp1	1	0.37	1.78	0
121	INT327782	Regulation of Gene_expression of AQP1	1	0.36	1.63	0
122	INT262512	Localization of Aqp1	1	0.40	0.7	0
123	INT280597	Positive_regulation of Negative_regulation of Dbi	1	0.03	0	0