GO:0030225

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Name macrophage differentiation
Categary Process
Go Slim No
Go Link GO:0030225
Unique Molecular Interactions 663
Total Molecular Interactions 1035
Total Single Events 8385
Pain Genes Associated 17

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for macrophage differentiation. They are ordered first by their pain relevance and then by number of times they were reported for macrophage differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85
2 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
3 INT117008 Sfpi1 Regulation of Oprm1 1 0.56 0.56 1.49
4 INT151514 Olfr155 Negative_regulation of Gene_expression of VEGFA 1 0.00 1.8 1.42
5 INT351205 VEGFA Positive_regulation of Binding of MRGPRX1 1 0.08 0.65 1.35
6 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33
7 INT202042 CAMK2N2 Negative_regulation of MMP9 1 0.01 0.73 1.25
8 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
9 INT187172 RPS3AP9 Negative_regulation of MMP9 1 0.00 0.89 1.2
10 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
11 INT99691 Pdpk1 Positive_regulation of Positive_regulation of VEGFA 1 0.01 0.72 1.11
12 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1
13 INT98555 Oprm1 Positive_regulation of Casp8 1 0.51 0.36 1.02
14 INT41659 IL31RA Regulation of PRL 1 0.22 1.07 0.98
15 INT41658 IL31RA Regulation of GH1 1 0.09 1.07 0.98
16 INT187111 TIMP2 Regulation of MMP9 1 0.23 1.47 0.97
17 INT161231 Positive_regulation of Htr1a Positive_regulation of Gene_expression of VEGFA 1 0.67 0.16 0.95
18 INT137922 VEGFA Positive_regulation of Oprm1 1 0.06 0 0.94
19 INT266659 Binding of MMP9 and MOCS1 1 0.01 1.71 0.94
20 INT117005 Sfpi1 Positive_regulation of Oprm1 1 0.52 0.56 0.94
21 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
22 INT137921 VEGFA Positive_regulation of Ephb2 1 0.03 0 0.93
23 INT116108 VEGFA Positive_regulation of SEC23IP 1 0.10 0.3 0.83
24 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
25 INT116106 VEGFA Positive_regulation of AKT1 1 0.12 0.3 0.83
26 INT196525 Binding of MMP2 and MMP9 2 0.32 2.49 0.78
27 INT295711 MMP9 Positive_regulation of Localization of VEGFA 1 0.06 0.29 0.74
28 INT259556 PLEK Negative_regulation of Gene_expression of VEGFA 1 0.46 2.15 0.73
29 INT259557 PLEK Negative_regulation of Positive_regulation of VEGFA 1 0.46 2.15 0.73
30 INT120018 VEGFA Positive_regulation of CCL3 1 0.01 1 0.7
31 INT120020 VEGFA Positive_regulation of CCL2 1 0.00 1 0.7
32 INT295720 PTGER2 Regulation of MMP9 1 0.01 0.53 0.7
33 INT120036 VEGFA Positive_regulation of Prap1 1 0.00 1 0.7
34 INT324900 VEGFA Positive_regulation of Gene_expression of Edn1 1 0.06 1.61 0.69
35 INT167355 VEGFA Regulation of RYBP 1 0.01 0.53 0.68
36 INT168295 PROC Regulation of Gene_expression of VEGFA 2 0.00 1.6 0.67
37 INT194857 Positive_regulation of Adora2a Positive_regulation of Gene_expression of Vegfa 1 0.23 0.74 0.67
38 INT136815 VEGFA Positive_regulation of Positive_regulation of RHOA 1 0.44 0.06 0.65
39 INT117007 Binding of Oprm1 and Sfpi1 1 0.50 0.07 0.63
40 INT174860 VEGFA Positive_regulation of Localization of CCL2 1 0.21 1.68 0.63
41 INT100369 HIF1A Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.99 0.62
42 INT302469 F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.82 0.62
43 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61
44 INT224731 Binding of VEGFA and Cia1 1 0.01 0.91 0.61
45 INT224733 Negative_regulation of Binding of VEGFA and Cia1 1 0.01 0.91 0.61
46 INT98629 VEGFA Positive_regulation of Gene_expression of EGR1 1 0.52 0.42 0.61
47 INT98628 VEGFA Positive_regulation of Transcription of EGR1 1 0.52 0.42 0.61
48 INT145661 Ptger2 Positive_regulation of Gene_expression of VEGFA 4 0.27 2.73 0.6
49 INT295724 CXCL12 Positive_regulation of MMP9 1 0.02 0.32 0.6
50 INT299286 VEGFA Positive_regulation of PI3 1 0.16 0.46 0.6
51 INT295721 CSF2 Positive_regulation of MMP9 1 0.06 0.32 0.6
52 INT202038 MMP9 Positive_regulation of IL8 1 0.05 0.29 0.59
53 INT202160 Binding of ARSD and CSF1R 1 0.16 1.69 0.59
54 INT342624 VEGFA Negative_regulation of Mmp2 1 0.09 1.54 0.58
55 INT350699 Binding of Casp8 and Stat3 1 0.04 1.81 0.58
56 INT350716 Binding of CD58 and Casp8 1 0.03 1.81 0.58
57 INT327339 Gtf3a Positive_regulation of VEGFA 1 0.00 2.34 0.58
58 INT304326 Ptger1 Positive_regulation of Gene_expression of VEGFA 1 0.19 1.37 0.57
59 INT342621 VEGFA Negative_regulation of Timp2 1 0.09 1.53 0.57
60 INT175626 TIMP1 Positive_regulation of Gene_expression of MMP9 1 0.03 0.72 0.57
61 INT173556 TIMP1 Negative_regulation of MMP9 1 0.02 0 0.56
62 INT175623 TIMP1 Positive_regulation of MMP9 1 0.03 0.71 0.56
63 INT176343 CHI3L1 Positive_regulation of Localization of CSF1 1 0.23 1.86 0.55
64 INT202157 Binding of CSF1R and SLC6A4 1 0.08 0.9 0.54
65 INT176342 CSF1 Positive_regulation of Localization of CSF2 1 0.26 1.84 0.54
66 INT162720 PEG3 Negative_regulation of Positive_regulation of CASP8 1 0.00 0.71 0.52
67 INT194918 Csf2 Positive_regulation of Gene_expression of VEGFA 1 0.02 0.85 0.52
68 INT194919 Kitl Positive_regulation of Gene_expression of VEGFA 1 0.01 0.85 0.52
69 INT97949 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of CDC42 1 0.06 0.72 0.51
70 INT196524 Binding of MMP1 and MMP9 1 0.31 0.74 0.51
71 INT196519 Positive_regulation of Binding of MMP1 and MMP9 1 0.42 0.74 0.51
72 INT187116 TIMP2 Negative_regulation of MMP9 1 0.36 1.37 0.5
73 INT97953 ST3GAL3 Positive_regulation of CDC42 1 0.09 0.7 0.5
74 INT127430 VEGFA Negative_regulation of Gene_expression of TIMP1 1 0.43 0.6 0.5
75 INT117006 Sfpi1 Negative_regulation of Oprm1 1 0.39 0.29 0.49
76 INT327332 VEGFA Positive_regulation of Gene_expression of Hgfac 1 0.00 2.02 0.49
77 INT288376 IL17A Regulation of VEGFA 1 0.00 1.16 0.49
78 INT292814 Binding of VEGFA and Kdr 8 0.18 3.63 0.48
79 INT260858 IL6 Positive_regulation of Gene_expression of VEGFA 2 0.31 1.77 0.48
80 INT305547 VEGFA Positive_regulation of Gtf3a 2 0.00 1.83 0.48
81 INT260836 Il18 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.48
82 INT127664 Negative_regulation of PDE4A Negative_regulation of MMP9 1 0.37 0.76 0.48
83 INT127665 Negative_regulation of PDE4A Negative_regulation of Transcription of MMP9 1 0.37 0.76 0.48
84 INT331928 Negative_regulation of Cpox Negative_regulation of VEGFA 1 0.01 0.97 0.47
85 INT314053 VEGFA Positive_regulation of Gene_expression of Mmp2 1 0.02 0.2 0.47
86 INT260843 Il6 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47
87 INT260838 Il17a Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47
88 INT224698 Il17a Positive_regulation of Gene_expression of VEGFA 1 0.01 0.49 0.46
89 INT224699 Il18 Positive_regulation of Gene_expression of VEGFA 1 0.01 0.49 0.46
90 INT224451 Il1 Positive_regulation of Gene_expression of VEGFA 1 0.10 1.08 0.45
91 INT155085 CASP1 Negative_regulation of CASP8 1 0.29 1.25 0.44
92 INT224434 TNF Positive_regulation of VEGFA 1 0.10 2.04 0.44
93 INT121850 CASP8 Positive_regulation of Protein_catabolism of BID 2 0.21 1.81 0.43
94 INT311587 CXCL10 Regulation of Gene_expression of VEGFA 1 0.23 0.45 0.43
95 INT353109 Binding of VEGFA and Aes 1 0.02 3.93 0.43
96 INT311589 EGF Regulation of Gene_expression of VEGFA 1 0.18 0.51 0.43
97 INT254350 FASLG Negative_regulation of Gene_expression of VEGFA 1 0.06 0.92 0.42
98 INT226070 Binding of CRP and MMP9 1 0.51 1.13 0.42
99 INT153720 Binding of VEGFA and Pscs 1 0.32 3.12 0.41
100 INT121848 AKT1 Regulation of CASP8 1 0.18 0.52 0.41
101 INT41657 IL31RA Positive_regulation of CSF2 1 0.22 0.4 0.41
102 INT295709 PTGER2 Regulation of VEGFA 1 0.01 1.61 0.41
103 INT121855 CASP8 Regulation of ROS1 1 0.05 0.52 0.41
104 INT121849 CASP8 Positive_regulation of CYCS 1 0.35 0.48 0.4
105 INT121852 CASP8 Positive_regulation of Localization of CYCS 1 0.32 0.48 0.4
106 INT226072 Binding of MMP9 and SHBG 1 0.15 1.02 0.39
107 INT304319 Ptger1 Positive_regulation of Gene_expression of Vegfa 1 0.37 1.19 0.39
108 INT285205 Binding of VEGFA and SLEB1 1 0.05 5.12 0.38
109 INT342623 Binding of VEGFA and Col18a1 1 0.02 1.15 0.37
110 INT342606 Binding of MMP14 and VEGFA 1 0.08 1.16 0.37
111 INT277353 VEGFA Regulation of Mtor 1 0.02 1.11 0.37
112 INT277355 VEGFA Regulation of Trerf1 1 0.08 1.17 0.37
113 INT277354 Gene_expression of VEGFA Regulation of Mtor 1 0.02 1.1 0.37
114 INT277352 Gene_expression of VEGFA Regulation of Trerf1 1 0.08 1.16 0.37
115 INT298588 IL1B Regulation of Gene_expression of CSF1 1 0.35 0.59 0.36
116 INT329449 IL17A Regulation of Gene_expression of Vegfa 1 0.28 0.63 0.36
117 INT302466 Positive_regulation of F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.1 0.35
118 INT203395 Edn1 Positive_regulation of Vegfa 1 0.06 1.59 0.35
119 INT287380 Binding of VEGFA and Kdr 12 0.18 11.97 0.34
120 INT352231 VEGFA Negative_regulation of Cntf 1 0.04 0.22 0.34
121 INT352230 VEGFA Negative_regulation of Gene_expression of Cntf 1 0.04 0.22 0.34
122 INT352232 VEGFA Negative_regulation of Vegfa 1 0.02 0.21 0.34
123 INT295755 Fgf2 Regulation of MMP9 1 0.07 0.99 0.33
124 INT110691 Lta Positive_regulation of Gene_expression of VEGFA 1 0.24 0.48 0.33
125 INT295717 VEGFA Regulation of MMP9 1 0.01 0.98 0.33
126 INT340616 COL4A4 Regulation of MMP9 1 0.12 0.95 0.32
127 INT329448 IL17A Positive_regulation of Gene_expression of Vegfa 1 0.45 0.59 0.32
128 INT342457 CSF1 Negative_regulation of Gene_expression of CCR4 1 0.00 0.93 0.31
129 INT206704 Negative_regulation of Binding of KDR and VEGFA 4 0.39 5.18 0.3
130 INT187102 Negative_regulation of Binding of MMP9 and TIMP2 1 0.36 0.69 0.3
131 INT213062 PTGS1 Regulation of Gene_expression of MMP9 1 0.04 0.25 0.3
132 INT187106 Binding of MMP9 and TIMP2 1 0.30 0.69 0.3
133 INT210953 Binding of VEGFA and Csf2 1 0.00 0.47 0.3
134 INT281797 Positive_regulation of Chrna4 Positive_regulation of Gene_expression of VEGFA 1 0.01 0.43 0.3
135 INT187113 Binding of IGHG3 and MMP9 1 0.01 0.63 0.3
136 INT260896 CRH Positive_regulation of Localization of MMP9 1 0.15 0.15 0.3
137 INT187105 TIMP2 Negative_regulation of Positive_regulation of MMP9 1 0.36 0.36 0.29
138 INT266800 Dlst Positive_regulation of Localization of VEGFA 1 0.02 0.88 0.29
139 INT254353 Binding of VEGFA and MMRN1 1 0.00 0.81 0.28
140 INT177978 Binding of CSF1R and SNRNP70 1 0.02 1.49 0.28
141 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27
142 INT320794 Binding of VEGFA and Flt4 4 0.08 3.04 0.27
143 INT103156 Tnf Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.94 0.27
144 INT287699 TNF Regulation of Binding of VEGFA 1 0.02 0.46 0.27
145 INT318551 Binding of VEGFA and Adamts1 1 0.13 1.13 0.27
146 INT285238 EGF Positive_regulation of VEGFA 1 0.01 1.55 0.27
147 INT342458 CSF1 Positive_regulation of Gene_expression of CCL2 1 0.17 0.84 0.27
148 INT177977 RUNX1 Regulation of CSF1R 1 0.14 1 0.27
149 INT248318 RETN Regulation of VEGFA 1 0.00 0.43 0.26
150 INT109538 Lox Negative_regulation of Transcription of VEGFA 1 0.30 0.69 0.26
151 INT260423 IFNA1 Positive_regulation of Gene_expression of VEGFA 1 0.01 1.28 0.26
152 INT254359 IL1B Positive_regulation of Localization of VEGFA 1 0.01 0.87 0.26
153 INT103152 TNF Positive_regulation of Positive_regulation of VEGFA 1 0.09 0.93 0.26
154 INT126886 Protein_catabolism of SP1 Negative_regulation of Gene_expression of VEGFA 1 0.03 0.49 0.26
155 INT126887 Protein_catabolism of SP4 Negative_regulation of Gene_expression of VEGFA 1 0.15 0.49 0.26
156 INT302468 INCENP Positive_regulation of Gene_expression of MMP9 1 0.01 0.72 0.26
157 INT266803 Dlst Positive_regulation of VEGFA 1 0.01 0.96 0.25
158 INT109539 Lox Negative_regulation of VEGFA 1 0.40 0.68 0.25
159 INT145660 Zfp329 Positive_regulation of Gene_expression of VEGFA 1 0.00 0.51 0.25
160 INT241401 VEGFA Positive_regulation of Gene_expression of Gopc 1 0.11 0.85 0.25
161 INT256227 Binding of EDN1 and VEGFA 1 0.18 2.92 0.25
162 INT98631 Negative_regulation of VEGFA Positive_regulation of EGR1 1 0.44 0.18 0.24
163 INT290376 Binding of CSF1R and MEFV 1 0.29 0.31 0.24
164 INT178077 EDN1 Positive_regulation of MMP9 1 0.06 0.88 0.24
165 INT98630 VEGFA Positive_regulation of EGR1 1 0.52 0.18 0.24
166 INT205155 Negative_regulation of Binding of CD44 and MMP9 1 0.32 1.98 0.23
167 INT213061 PTGER2 Regulation of Gene_expression of MMP9 1 0.03 0.25 0.23
168 INT304323 VEGFA Positive_regulation of Gene_expression of Ptger2 1 0.27 0.16 0.23
169 INT118840 VEGFA Regulation of Positive_regulation of Mb 1 0.05 0.36 0.23
170 INT163403 VEGFA Positive_regulation of MMP2 1 0.52 0.13 0.23
171 INT292565 MAP3K5 Positive_regulation of Positive_regulation of CDC42 1 0.02 0 0.23
172 INT323436 VEGFA Regulation of Kdr 1 0.03 0.77 0.23
173 INT304321 Ptger4 Positive_regulation of Gene_expression of VEGFA 1 0.27 0.59 0.23
174 INT304324 VEGFA Positive_regulation of Gene_expression of Ptger4 1 0.27 0.16 0.23
175 INT245866 Binding of VEGFA and Fgf1 1 0.07 0.52 0.22
176 INT118838 Gene_expression of Vegfa Positive_regulation of Gene_expression of Mb 1 0.44 0.4 0.22
177 INT285745 IL31RA Positive_regulation of Gene_expression of MPL 1 0.19 1.04 0.22
178 INT318189 MUC5AC Regulation of Gene_expression of VEGFA 1 0.21 1.17 0.22
179 INT187117 Negative_regulation of TIMP2 Negative_regulation of MMP9 1 0.36 0.6 0.22
180 INT137611 Crh Positive_regulation of Vegfa 1 0.43 0.49 0.21
181 INT116467 Vegfa Positive_regulation of Akt1 1 0.33 1.41 0.21
182 INT137612 Crh Positive_regulation of Positive_regulation of Vegfa 1 0.43 0.43 0.21
183 INT114837 Il1b Negative_regulation of Vegfa 1 0.26 3.04 0.21
184 INT163096 Tlr2 Positive_regulation of Gene_expression of VEGFA 1 0.07 0.16 0.21
185 INT116469 VEGFA Positive_regulation of Amfr 1 0.01 1.39 0.21
186 INT116468 VEGFA Positive_regulation of Akt1 1 0.04 1.39 0.21
187 INT116466 Vegfa Positive_regulation of Amfr 1 0.07 1.41 0.21
188 INT137610 Crh Positive_regulation of Localization of Vegfa 1 0.43 0.49 0.21
189 INT345196 Lpar2 Positive_regulation of Gene_expression of VEGFA 1 0.08 2.14 0.2
190 INT174861 Binding of FGF2 and VEGFA 1 0.34 0.59 0.2
191 INT236405 Mthfs Regulation of Gene_expression of VEGFA 1 0.00 0.25 0.2
192 INT287894 VEGFA Positive_regulation of Localization of BMP4 1 0.04 2.49 0.2
193 INT142578 Binding of CSF1 and Crp 1 0.01 1.2 0.2
194 INT189553 DCN Negative_regulation of Transcription of VEGFA 1 0.06 0.78 0.2
195 INT175948 TNF Positive_regulation of Positive_regulation of CASP8 1 0.02 1.12 0.2
196 INT325470 MMP3 Positive_regulation of MMP9 1 0.17 0.9 0.2
197 INT175947 TNFSF10 Positive_regulation of Positive_regulation of CASP8 1 0.01 1.12 0.2
198 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19
199 INT175727 IL1B Regulation of VEGFA 2 0.04 0.7 0.19
200 INT280275 Tgfb1 Positive_regulation of VEGFA 1 0.02 2.46 0.19

Single Events

The table below shows the top 100 pain related interactions that have been reported for macrophage differentiation. They are ordered first by their pain relevance and then by number of times they were reported in macrophage differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2
2 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65
3 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73
4 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81
5 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53
6 INT101992 Localization of VEGFA 413 0.81 258.23 36.15
7 INT99610 Localization of MMP9 126 0.79 48.46 32.67
8 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52
9 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1
10 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42
11 INT48692 Binding of VEGFA 345 0.48 210.3 21.31
12 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14
13 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03
14 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7
15 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89
16 INT46619 Gene_expression of CSF1 80 0.73 36.63 12.94
17 INT93715 Negative_regulation of MMP9 69 0.55 36.05 11.73
18 INT89282 Regulation of MMP9 39 0.60 25.45 10.34
19 INT98130 Positive_regulation of CASP8 79 0.67 65.29 10.08
20 INT17283 Positive_regulation of CSF1 37 0.59 24.16 10.01
21 INT126031 Negative_regulation of Gene_expression of MMP9 40 0.57 22.71 9.79
22 INT187190 Positive_regulation of Localization of MMP9 27 0.68 8.1 8.93
23 INT43721 Gene_expression of Vegfa 49 0.77 36.18 6.63
24 INT111545 Phosphorylation of VEGFA 50 0.76 22.19 5.88
25 INT86111 Positive_regulation of Positive_regulation of VEGFA 38 0.69 33.81 5.78
26 INT15542 Negative_regulation of CASP8 20 0.41 17.3 5.63
27 INT152433 Binding of CSF1R 6 0.33 10.97 5.54
28 INT99606 Negative_regulation of Localization of MMP9 23 0.57 7.15 5.47
29 INT117004 Gene_expression of Sfpi1 21 0.75 15.95 5.29
30 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9
31 INT99690 Negative_regulation of Positive_regulation of VEGFA 30 0.58 14.56 4.79
32 INT103153 Positive_regulation of Transcription of VEGFA 34 0.69 22.16 4.22
33 INT156097 Negative_regulation of Localization of VEGFA 70 0.58 34.96 4.17
34 INT99608 Transcription of MMP9 18 0.65 9.67 4.11
35 INT118835 Positive_regulation of Vegfa 18 0.59 11.2 3.91
36 INT133312 Binding of MMP9 25 0.42 16.79 3.83
37 INT152254 Gene_expression of CSF1R 16 0.75 12.93 3.81
38 INT46621 Positive_regulation of Gene_expression of CSF1 17 0.47 10.53 3.59
39 INT99687 Negative_regulation of Transcription of VEGFA 17 0.43 10.3 3.25
40 INT111547 Negative_regulation of Phosphorylation of VEGFA 13 0.42 5.08 3.22
41 INT137609 Localization of Vegfa 22 0.78 14.67 3.01
42 INT177993 Localization of CSF1R 4 0.73 7.49 2.94
43 INT46620 Positive_regulation of Positive_regulation of CSF1 1 0.12 2.9 2.94
44 INT98554 Positive_regulation of Casp8 20 0.67 21.32 2.9
45 INT178002 Positive_regulation of CSF1R 2 0.37 6.52 2.74
46 INT143952 Regulation of Gene_expression of MMP9 14 0.53 10.16 2.73
47 INT43719 Positive_regulation of Vegfa 21 0.69 5.15 2.64
48 INT15543 Gene_expression of CASP8 32 0.75 25.6 2.61
49 INT183810 Positive_regulation of Positive_regulation of MMP9 9 0.52 4.15 2.46
50 INT113164 Regulation of Regulation of VEGFA 6 0.36 5.96 2.43
51 INT123528 Negative_regulation of Gene_expression of Vegfa 10 0.57 7.08 2.31
52 INT43723 Regulation of Vegfa 9 0.34 4.96 2.28
53 INT109970 Negative_regulation of Casp8 5 0.52 9.34 2.19
54 INT116194 Gene_expression of Casp8 14 0.75 14.61 2.13
55 INT105247 Positive_regulation of Gene_expression of Vegfa 12 0.67 12.07 2.05
56 INT136818 Positive_regulation of Phosphorylation of VEGFA 4 0.46 0.81 2.02
57 INT103244 Protein_catabolism of MMP9 12 0.72 11.81 2.01
58 INT122195 Regulation of Localization of VEGFA 13 0.57 10.61 1.92
59 INT41660 Regulation of IL31RA 2 0.45 1.46 1.81
60 INT117003 Binding of Sfpi1 5 0.47 5.04 1.74
61 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73
62 INT118833 Positive_regulation of Gene_expression of Vegfa 11 0.65 8.14 1.7
63 INT12442 Localization of Vegfa 11 0.73 4.85 1.68
64 INT15544 Regulation of CASP8 6 0.41 5.83 1.63
65 INT105248 Negative_regulation of Vegfa 8 0.47 6.19 1.61
66 INT186724 Negative_regulation of Transcription of MMP9 5 0.37 1.59 1.57
67 INT127724 Localization of CSF1 12 0.73 9.35 1.56
68 INT295688 Positive_regulation of Regulation of MMP9 1 0.14 0.67 1.51
69 INT89116 Regulation of Positive_regulation of VEGFA 8 0.43 6.62 1.5
70 INT109536 Negative_regulation of Vegfa 15 0.46 10.35 1.39
71 INT15541 Positive_regulation of Negative_regulation of CASP8 2 0.31 1.23 1.31
72 INT202161 Negative_regulation of CSF1R 3 0.31 3.36 1.22
73 INT97955 Positive_regulation of CDC42 8 0.49 2.47 1.19
74 INT15419 Gene_expression of IL31RA 6 0.65 5.02 1.19
75 INT137607 Positive_regulation of Localization of Vegfa 7 0.49 3.72 1.18
76 INT188376 Negative_regulation of Gene_expression of Vegfa 5 0.30 5.29 1.18
77 INT187123 Negative_regulation of Positive_regulation of MMP9 7 0.42 2.54 1.17
78 INT62496 Binding of CSF1 6 0.36 4.55 1.14
79 INT110394 Regulation of CSF1R 3 0.38 2.49 1.12
80 INT143956 Regulation of Positive_regulation of MMP9 5 0.40 2.61 1.11
81 INT96579 Negative_regulation of Negative_regulation of MMP9 5 0.40 4.55 1.04
82 INT117002 Negative_regulation of Sfpi1 16 0.58 9.72 1
83 INT112717 Negative_regulation of Binding of VEGFA 21 0.56 11.07 0.99
84 INT187135 Positive_regulation of Negative_regulation of MMP9 3 0.43 1.87 0.92
85 INT142122 Regulation of Gene_expression of Bmp4 5 0.43 2.69 0.86
86 INT211488 Regulation of Binding of VEGFA 5 0.43 3.72 0.83
87 INT191101 Regulation of Localization of MMP9 6 0.38 2.49 0.81
88 INT187132 Negative_regulation of Binding of MMP9 5 0.36 3.15 0.81
89 INT210247 Positive_regulation of Bmp4 6 0.65 4.36 0.8
90 INT174194 Negative_regulation of Gene_expression of CSF1 3 0.33 2.05 0.8
91 INT142016 Negative_regulation of Gene_expression of CEBPA 1 0.41 0.67 0.8
92 INT142018 Gene_expression of CEBPA 1 0.75 0.66 0.8
93 INT173082 Positive_regulation of Binding of VEGFA 20 0.48 11.16 0.79
94 INT72628 Regulation of CSF1 7 0.25 1.95 0.75
95 INT143445 Protein_catabolism of VEGFA 12 0.85 4.14 0.72
96 INT12443 Regulation of Localization of Vegfa 2 0.20 0 0.72
97 INT156875 Positive_regulation of Gene_expression of Casp8 2 0.49 2.49 0.7
98 INT340625 Protein_catabolism of Vegfa 1 0.05 1.61 0.64
99 INT96422 Gene_expression of Bmp4 18 0.69 3.26 0.63
100 INT174868 Regulation of Negative_regulation of VEGFA 4 0.43 4.51 0.63
101 INT202163 Negative_regulation of Localization of CSF1R 1 0.31 1.76 0.63
102 INT125867 Protein_catabolism of CASP8 9 0.65 8.5 0.57
103 INT174873 Regulation of Transcription of VEGFA 8 0.43 3.71 0.55
104 INT97956 Negative_regulation of CDC42 3 0.27 1.58 0.55
105 INT172964 Binding of Vegfa 14 0.47 10.62 0.53
106 INT162721 Negative_regulation of Positive_regulation of CASP8 3 0.12 3.17 0.52
107 INT105677 Binding of Vegfa 7 0.37 5.22 0.51
108 INT178000 Positive_regulation of Gene_expression of CSF1R 1 0.46 0.85 0.46
109 INT312528 Binding of Spib 1 0.00 1.46 0.46
110 INT142124 Binding of Bmp4 1 0.35 0.46 0.45
111 INT285756 Positive_regulation of IL31RA 1 0.45 2.01 0.44
112 INT247568 Negative_regulation of Negative_regulation of VEGFA 5 0.41 5.35 0.43
113 INT268877 Regulation of Gene_expression of Vegfa 2 0.58 4.73 0.42
114 INT152023 Regulation of Vegfa 4 0.52 3.99 0.41
115 INT180688 Transcription of Bmp4 3 0.58 0.35 0.41
116 INT180702 Positive_regulation of Transcription of Bmp4 3 0.42 0.35 0.41
117 INT43720 Regulation of Positive_regulation of Vegfa 1 0.03 0.41 0.41
118 INT43722 Positive_regulation of Regulation of Vegfa 1 0.06 0.41 0.41
119 INT290389 Positive_regulation of Binding of CSF1R 1 0.25 1.14 0.4
120 INT142872 Regulation of Casp8 6 0.29 3.11 0.39
121 INT129849 Positive_regulation of Localization of Vegfa 1 0.46 0.35 0.39
122 INT181025 Localization of Sfpi1 3 0.80 4.96 0.38
123 INT84555 Negative_regulation of Spi1 6 0.42 0.71 0.34
124 INT187022 Positive_regulation of Transcription of MMP9 3 0.45 3.27 0.34
125 INT177994 Negative_regulation of Phosphorylation of CSF1R 1 0.39 1 0.34
126 INT295690 Negative_regulation of Regulation of MMP9 1 0.11 0.99 0.33
127 INT177999 Phosphorylation of CSF1R 1 0.75 0.99 0.33
128 INT181020 Positive_regulation of Gene_expression of Sfpi1 2 0.67 1.11 0.31
129 INT166099 Phosphorylation of MMP9 2 0.41 0.52 0.29
130 INT181051 Transcription of Sfpi1 1 0.62 1.1 0.29
131 INT135546 Positive_regulation of Positive_regulation of CASP8 13 0.31 10.97 0.28
132 INT159213 Gene_expression of BMP4 8 0.74 2.1 0.28
133 INT159212 Positive_regulation of Gene_expression of BMP4 2 0.66 0.91 0.28
134 INT176260 Binding of CASP8 5 0.36 2.73 0.27
135 INT224619 Regulation of Positive_regulation of Vegfa 1 0.05 0.57 0.27
136 INT224638 Positive_regulation of Positive_regulation of Vegfa 1 0.06 0.57 0.27
137 INT159323 Negative_regulation of Protein_catabolism of CASP8 1 0.31 0.59 0.27
138 INT167206 Positive_regulation of Positive_regulation of Casp8 4 0.49 2.11 0.26
139 INT148796 Regulation of Phosphorylation of VEGFA 3 0.35 1.66 0.26
140 INT109537 Transcription of Vegfa 2 0.44 1.32 0.26
141 INT185009 Negative_regulation of BMP4 2 0.56 1.04 0.25
142 INT290388 Regulation of Gene_expression of CSF1R 1 0.24 0.84 0.25
143 INT137608 Regulation of Localization of Vegfa 1 0.25 0.56 0.24
144 INT183881 Localization of CDC42 3 0.49 1.92 0.23
145 INT101308 Positive_regulation of Spi1 2 0.67 0.38 0.23
146 INT83716 Negative_regulation of CSF1 3 0.23 0.43 0.21
147 INT142121 Positive_regulation of Gene_expression of Bmp4 3 0.47 7 0.21
148 INT181036 Positive_regulation of Sfpi1 3 0.49 0.96 0.21
149 INT206159 Negative_regulation of Regulation of VEGFA 3 0.24 2.38 0.2
150 INT183876 Regulation of CDC42 3 0.30 1.94 0.19
151 INT101309 Gene_expression of Spi1 2 0.75 0.64 0.18
152 INT101307 Positive_regulation of Gene_expression of Spi1 1 0.67 0.28 0.18
153 INT106451 Regulation of Spi1 1 0.43 0 0.18
154 INT120085 Negative_regulation of Gene_expression of Bmp4 5 0.55 0.61 0.17
155 INT116193 Protein_catabolism of Casp8 5 0.17 4.37 0.17
156 INT335331 Regulation of Negative_regulation of MMP9 1 0.11 0.18 0.17
157 INT325474 Regulation of Regulation of MMP9 1 0.53 0.96 0.14
158 INT181033 Regulation of Sfpi1 2 0.40 1.58 0.13
159 INT194588 Localization of IL31RA 1 0.73 0.07 0.13
160 INT206133 Binding of CDC42 3 0.25 0.8 0.12
161 INT302444 Negative_regulation of Binding of Vegfa 2 0.57 4.08 0.12
162 INT246872 Negative_regulation of Localization of Vegfa 2 0.41 2.16 0.12
163 INT260740 Negative_regulation of Localization of Vegfa 1 0.10 0.19 0.12
164 INT185014 Regulation of Transcription of MMP9 2 0.43 0.56 0.11
165 INT287912 Localization of BMP4 1 0.18 1.13 0.1
166 INT185901 Localization of CASP8 7 0.55 5.38 0.09
167 INT184511 Positive_regulation of Negative_regulation of VEGFA 5 0.46 2.86 0.09
168 INT199848 Binding of Casp8 3 0.15 3.29 0.09
169 INT196033 Negative_regulation of Gene_expression of Bmp4 3 0.21 0.45 0.09
170 INT224425 Regulation of Gene_expression of CSF1 1 0.25 0.4 0.09
171 INT247569 Positive_regulation of Regulation of VEGFA 6 0.48 4.15 0.07
172 INT210243 Negative_regulation of Bmp4 1 0.55 0.55 0.07
173 INT127726 Negative_regulation of Localization of CSF1 1 0.10 0.27 0.06
174 INT206169 Gene_expression of CDC42 2 0.26 1.05 0.05
175 INT206167 Positive_regulation of Gene_expression of CDC42 1 0.08 0.05 0.05
176 INT187440 Positive_regulation of Binding of MMP9 1 0.16 0.45 0.05
177 INT196030 Positive_regulation of Bmp4 6 0.62 2.55 0.04
178 INT336053 Regulation of Positive_regulation of CASP8 2 0.04 1.44 0.04
179 INT256923 Regulation of Gene_expression of Casp8 2 0.11 2.31 0.04
180 INT294427 Regulation of Gene_expression of Vegfa 2 0.44 2.4 0.04
181 INT210238 Positive_regulation of Negative_regulation of Bmp4 1 0.47 0 0.04
182 INT253182 Positive_regulation of Positive_regulation of Bmp4 1 0.45 0.58 0.04
183 INT199851 Positive_regulation of Protein_catabolism of Casp8 1 0.07 1.04 0.04
184 INT292858 Localization of Casp8 2 0.27 1.68 0.03
185 INT295840 Positive_regulation of Regulation of Vegfa 1 0.12 0 0.03
186 INT205170 Positive_regulation of Phosphorylation of MMP9 1 0.30 0.25 0.03
187 INT237978 Negative_regulation of Negative_regulation of CASP8 1 0.07 1.65 0.03
188 INT205166 Regulation of Binding of MMP9 1 0.34 0.26 0.03
189 INT310472 Negative_regulation of Gene_expression of Sfpi1 1 0.41 0.23 0.03
190 INT234430 Negative_regulation of Gene_expression of CASP8 4 0.06 3.79 0
191 INT196034 Positive_regulation of Gene_expression of Bmp4 4 0.45 0.63 0
192 INT260779 Negative_regulation of Bmp4 4 0.23 0.94 0
193 INT265477 Positive_regulation of Gene_expression of CASP8 2 0.17 1.57 0
194 INT234423 Regulation of Gene_expression of CASP8 2 0.07 3.03 0
195 INT196027 Binding of Bmp4 2 0.13 0.97 0
196 INT142119 Regulation of Bmp4 2 0.58 0.29 0
197 INT112325 Transcription of Vegfa 2 0.41 1.11 0
198 INT203927 Positive_regulation of Localization of CASP8 2 0.08 1.98 0
199 INT234405 Regulation of Negative_regulation of CASP8 1 0.09 3.05 0
200 INT143447 Regulation of Protein_catabolism of VEGFA 1 0.27 0.15 0
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