GO:0030238

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Name male sex determination
Categary Process
Go Slim No
Go Link GO:0030238
Unique Molecular Interactions 237
Total Molecular Interactions 336
Total Single Events 3036
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for male sex determination. They are ordered first by their pain relevance and then by number of times they were reported for male sex determination. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
2 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
3 INT111758 Binding of Drd2 and Insrr 1 0.01 0.94 4.33
4 INT32911 Binding of Insrr and Rbm39 2 0.00 0 3.95
5 INT73071 Binding of Cpe and Insrr 3 0.01 0.33 3.38
6 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
7 INT128292 Nts Positive_regulation of Insr 1 0.03 0.99 3.34
8 INT128291 Vom1r68 Positive_regulation of Insr 1 0.00 0.99 3.33
9 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
10 INT111757 Positive_regulation of Binding of Drd2 and Insrr 1 0.02 0.64 2.89
11 INT63919 Binding of Cck and Insrr 1 0.01 0 2.08
12 INT73072 Negative_regulation of Binding of Cpe and Insrr 1 0.00 0 1.94
13 INT99138 Coq10a Regulation of Insrr 1 0.01 0.73 1.81
14 INT168716 Mapk8 Negative_regulation of Insrr 1 0.01 0.25 1.75
15 INT90929 Binding of Ap1m1 and Insrr 1 0.01 0.19 1.6
16 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
17 INT159657 Binding of INSRR and NGF 3 0.00 1.65 1.48
18 INT39109 Binding of INSRR and PDYN 1 0.15 0.45 1.46
19 INT111761 Positive_regulation of Binding of Cpe and Insrr 1 0.01 0.33 1.43
20 INT125856 Positive_regulation of Oprm1 Regulation of Positive_regulation of Insrr 1 0.01 0.26 1.43
21 INT138099 Binding of Grin2a and Insrr 1 0.01 0.36 1.39
22 INT290542 Crh Positive_regulation of Insr 1 0.02 0.36 1.36
23 INT38624 Binding of Oprm1 and Insrr 2 0.01 0.24 1.31
24 INT132943 Insrr Positive_regulation of Rbm39 1 0.00 0 1.27
25 INT71109 Binding of INSRR and MC1R 1 0.01 0 1.27
26 INT132944 Positive_regulation of Insrr Positive_regulation of Rbm39 1 0.00 0 1.27
27 INT71989 Binding of Pdyn and Insrr 1 0.01 0 1.27
28 INT71990 Negative_regulation of Binding of Pdyn and Insrr 1 0.01 0 1.27
29 INT159655 Binding of BDNF and INSRR 2 0.00 1.25 1.26
30 INT99695 Binding of Tspo and Insrr 1 0.02 0.52 1.25
31 INT125857 Insrr Negative_regulation of Oprm1 1 0.01 0.27 1.24
32 INT150595 Binding of Oprk1 and Insrr 1 0.01 0.07 1.23
33 INT151454 Binding of Calca and Insrr 1 0.02 0.31 1.22
34 INT63384 Binding of Cnr1 and Insrr 1 0.03 0.24 1.2
35 INT256297 Binding of Creb1 and Insrr 1 0.00 1.22 1.19
36 INT32871 Binding of Insrr and Adarb1 1 0.01 0 1.18
37 INT256293 Binding of Grin2b and Insrr 1 0.01 1.06 1.05
38 INT267886 Arl10 Positive_regulation of Insrr 1 0.00 0.07 0.98
39 INT56205 Binding of Ap1m2 and Insrr 1 0.00 0.07 0.96
40 INT296278 Insrr Positive_regulation of Cysltr1 1 0.00 0.99 0.92
41 INT59503 Binding of Oprd1 and Insrr 1 0.00 0 0.89
42 INT151961 Rbm39 Positive_regulation of Insrr 1 0.17 0.26 0.89
43 INT60719 Insrr Positive_regulation of Fos 1 0.03 1.23 0.84
44 INT114068 Agtr2 Regulation of Gene_expression of Insr 1 0.15 0.95 0.79
45 INT187229 Binding of Tnfsf11 and Insrr 1 0.00 2.06 0.78
46 INT70058 Binding of Pnoc and Insrr 1 0.01 0.09 0.77
47 INT76499 Binding of Insr and Adora2a 1 0.08 0 0.76
48 INT111904 Binding of Gabrg1 and Insrr 1 0.02 0 0.74
49 INT33479 Positive_regulation of Oprl1 Positive_regulation of Gene_expression of Insrr 1 0.17 0.15 0.73
50 INT114860 Negative_regulation of Insrr Positive_regulation of Casp3 1 0.02 0.71 0.73
51 INT290544 Negative_regulation of Crh Positive_regulation of Insr 1 0.01 0.3 0.72
52 INT70011 Binding of Hrh1 and Insrr 1 0.00 0.4 0.72
53 INT341534 INSRR Positive_regulation of F2RL1 1 0.00 1.4 0.7
54 INT144459 Binding of GPM6A and INSRR 1 0.00 0 0.67
55 INT81407 Binding of Oprl1 and Insrr 1 0.02 0.13 0.66
56 INT290549 Gopc Positive_regulation of Positive_regulation of Insr 1 0.01 0.06 0.65
57 INT94020 Binding of EDN2 and INSRR 1 0.03 0 0.65
58 INT290545 Crh Positive_regulation of Positive_regulation of Insr 1 0.02 0.06 0.64
59 INT290550 Gopc Positive_regulation of Insr 1 0.01 0.06 0.64
60 INT267888 St13 Positive_regulation of Insrr 1 0.00 0.07 0.64
61 INT267891 Cpe Positive_regulation of Localization of Insrr 1 0.00 0 0.64
62 INT290540 Positive_regulation of Crh Positive_regulation of Insr 1 0.02 0.06 0.64
63 INT46493 Binding of Insr and Oxt 1 0.14 0 0.62
64 INT200808 Binding of Akt1 and Insrr 2 0.00 0.98 0.61
65 INT276217 Pdk1 Positive_regulation of Positive_regulation of Insr 1 0.05 0.1 0.6
66 INT131642 Edn1 Positive_regulation of Positive_regulation of Insrr 1 0.01 0.44 0.6
67 INT113163 Insrr Positive_regulation of Pscs 1 0.04 0 0.6
68 INT89010 Arc Positive_regulation of Insr 1 0.08 0.86 0.59
69 INT249029 Binding of Csn2 and Insrr 1 0.00 0 0.59
70 INT89012 DST Positive_regulation of Insr 1 0.01 0.86 0.59
71 INT267887 St13 Positive_regulation of Localization of Insrr 1 0.00 0 0.58
72 INT81792 AGRP Negative_regulation of INSRR 3 0.01 0 0.55
73 INT113162 Lep Positive_regulation of Positive_regulation of Insrr 1 0.03 0 0.55
74 INT267890 Arl10 Regulation of Insrr 1 0.00 0.43 0.54
75 INT261497 Binding of PTGDR and LMOD1 1 0.00 0.51 0.54
76 INT85265 Binding of Il1rn and Insrr 1 0.01 0 0.54
77 INT267889 St13 Regulation of Insrr 1 0.00 0.43 0.54
78 INT114070 Agtr2 Positive_regulation of Gene_expression of Insr 1 0.13 0.34 0.52
79 INT94015 Binding of EDN1 and INSRR 1 0.04 0 0.49
80 INT114065 Akt1 Regulation of Gene_expression of Insr 1 0.13 0.28 0.46
81 INT37599 Ace Regulation of Localization of Insr 1 0.18 0 0.46
82 INT151455 Binding of Insrr and Gtf3a 1 0.00 0.21 0.46
83 INT151456 Binding of KITLG and Insrr 1 0.00 0.21 0.46
84 INT89649 INSRR Regulation of ADCY1 1 0.00 0.07 0.44
85 INT126339 Pax3 Regulation of Insrr 1 0.00 0.56 0.44
86 INT126338 Insrr Regulation of Gene_expression of Ifng 1 0.00 0.56 0.43
87 INT60718 Negative_regulation of Insrr Positive_regulation of Fos 1 0.01 0.6 0.42
88 INT285725 Binding of IGF1R and INS 1 0.27 0.07 0.4
89 INT29052 Binding of INS and INSRR 1 0.02 0.23 0.4
90 INT29053 Regulation of Binding of INS and INSRR 1 0.01 0.24 0.4
91 INT114067 Ace Regulation of Insr 1 0.09 0.31 0.39
92 INT283842 Binding of hb and Insrr 1 0.01 1.35 0.38
93 INT70010 Binding of Neurod1 and Insrr 1 0.01 0.11 0.37
94 INT70009 Binding of Gabpb1 and Insrr 1 0.00 0.11 0.37
95 INT67288 Binding of Insrr and Positive_regulation of Localization of Abat 1 0.00 0.18 0.37
96 INT336573 Ptpn2 Regulation of INSR 1 0.00 1.36 0.36
97 INT242403 INSR Positive_regulation of Gene_expression of Bdkrb1 1 0.45 0.88 0.35
98 INT189687 INSRR Negative_regulation of Transcription of TERT 1 0.00 0.24 0.35
99 INT71518 Binding of INSRR and Nisch 1 0.00 0.22 0.35
100 INT136008 Binding of BDKRB2 and INSRR 1 0.01 0.17 0.34
101 INT136007 Binding of INSRR and KNG1 1 0.00 0.17 0.34
102 INT99676 Cck Positive_regulation of Insrr 1 0.11 0.07 0.33
103 INT283841 Dlg4 Negative_regulation of Insrr 1 0.01 0.95 0.33
104 INT84426 Binding of TSPO and INSRR 1 0.01 0.22 0.3
105 INT70184 INSRR Positive_regulation of FOS 1 0.03 0.09 0.29
106 INT334668 Gria2 Regulation of Gene_expression of Insrr 1 0.01 0.27 0.29
107 INT213802 Il4 Regulation of Gene_expression of Insrr 1 0.00 0.76 0.29
108 INT70186 PRCP Positive_regulation of INSRR 1 0.01 0.09 0.29
109 INT120236 Binding of Ncoa1 and Insrr 1 0.00 0.15 0.28
110 INT274946 Binding of Pick1 and Insrr 1 0.00 0 0.28
111 INT274932 Binding of Insrr and Map3k1 1 0.00 0 0.28
112 INT120237 Positive_regulation of Binding of Ncoa1 and Insrr 1 0.00 0.15 0.28
113 INT213808 Il12a Regulation of Gene_expression of Insrr 1 0.00 0.76 0.28
114 INT311918 Insrr Negative_regulation of Tgfbr1 1 0.00 0.87 0.26
115 INT311900 Acvrl1 Negative_regulation of Insrr 1 0.00 0.86 0.25
116 INT41406 Binding of Insr and Thtpa 1 0.05 0 0.25
117 INT189692 INSRR Positive_regulation of PRKCA 1 0.00 0 0.24
118 INT92581 IGF1R Positive_regulation of Gene_expression of PTGER2 1 0.09 0.79 0.24
119 INT50619 Positive_regulation of Insrr Positive_regulation of Fos 1 0.07 0 0.23
120 INT192331 UBR7 Negative_regulation of INSRR 1 0.00 0.54 0.23
121 INT267885 Binding of Insrr and St13 1 0.00 0.09 0.23
122 INT89158 Grpr Positive_regulation of Localization of Insr 1 0.02 0 0.23
123 INT69869 Binding of Ptgdr and Ptgds 1 0.06 0 0.22
124 INT288854 Binding of PTGDR and PHGDH 1 0.00 1.04 0.21
125 INT334631 Igf1r Positive_regulation of Phosphorylation of Akt1 1 0.19 0.5 0.18
126 INT58579 Binding of INSRR and RPA1 1 0.00 0 0.18
127 INT263774 Neto1 Regulation of Insrr 1 0.00 0.28 0.18
128 INT127734 Binding of Insrr and Ogfr 1 0.01 0.35 0.17
129 INT94017 Binding of EDN3 and INSRR 1 0.03 0 0.16
130 INT94022 Positive_regulation of Binding of EDN1 and INSRR 1 0.06 0 0.16
131 INT224308 INSRR Regulation of VEGFA 1 0.00 1.42 0.16
132 INT94013 Positive_regulation of Binding of EDN2 and INSRR 1 0.04 0 0.16
133 INT94019 Positive_regulation of Binding of EDN3 and INSRR 1 0.04 0 0.16
134 INT168941 Irs2 Regulation of Gene_expression of Igf1r 1 0.39 0.91 0.16
135 INT58403 INSRR Negative_regulation of RTCA 1 0.00 0.06 0.15
136 INT189694 Negative_regulation of INSRR Negative_regulation of CHKB 1 0.00 0.07 0.15
137 INT334634 Binding of Igf1 and Igf1r 1 0.14 0.45 0.15
138 INT92582 IGF1R Positive_regulation of Transcription of PTGER2 1 0.09 0.43 0.15
139 INT189695 INSRR Negative_regulation of CHKB 1 0.00 0.07 0.15
140 INT316817 Ifnar1 Positive_regulation of Phosphorylation of Insrr 1 0.00 0.43 0.13
141 INT273018 Binding of FGF9 and PDE1A 1 0.18 0.3 0.11
142 INT273020 Binding of FGF9 and PDE11A 1 0.22 0.3 0.11
143 INT153028 Binding of INSRR and KCNMA1 1 0.06 0.29 0.1
144 INT153026 Binding of HTR3A and INSRR 1 0.13 0.29 0.1
145 INT143399 Binding of INSRR and NMU 1 0.01 0.12 0.09
146 INT349660 Binding of INSR and PYCARD 1 0.01 0 0.09
147 INT119859 Gabbr1 Positive_regulation of INSRR 1 0.00 0 0.09
148 INT109465 Dmp1 Positive_regulation of Insrr 1 0.00 0 0.08
149 INT325059 Insr Positive_regulation of Ang 1 0.02 1.4 0.08
150 INT115258 Insr Positive_regulation of Phosphorylation of Irs1 1 0.19 0.26 0.08
151 INT345370 Binding of Vegfa and Insrr 1 0.01 2.29 0.08
152 INT251775 AGK Negative_regulation of INSRR 1 0.00 1.1 0.07
153 INT355879 Binding of Sry and Eae1 1 0.05 1.34 0.07
154 INT223085 Binding of Pdgfb and Insrr 1 0.01 0.91 0.07
155 INT17920 Penk Positive_regulation of Insr 1 0.05 0.14 0.06
156 INT311906 Binding of Smad4 and Insrr 1 0.00 0.18 0.06
157 INT234619 IGF1 Regulation of IGF1R 1 0.11 0.39 0.05
158 INT234624 Binding of IGF1 and IGF1R 1 0.09 0.39 0.05
159 INT184123 Socs3 Positive_regulation of Protein_catabolism of Insr 1 0.03 0.41 0.05
160 INT189679 INSRR Regulation of Transcription of TERT 1 0.00 1 0.05
161 INT234620 Regulation of Binding of IGF1 and IGF1R 1 0.07 0.39 0.05
162 INT325060 Binding of Insr and Hand1 1 0.00 0.16 0.05
163 INT233303 Binding of CD4 and SRY 1 0.07 0.34 0.05
164 INT184085 Socs1 Positive_regulation of Protein_catabolism of Insr 1 0.04 0.41 0.05
165 INT342170 Insr Regulation of Localization of Cd320 1 0.08 0.92 0.04
166 INT322891 Sox9 Regulation of Transcription of Col2a1 1 0.10 0.12 0.04
167 INT225800 Binding of Insr and Enpp1 1 0.05 0.67 0.04
168 INT210260 Sox9 Negative_regulation of Cdx2 1 0.20 0 0.03
169 INT144761 Binding of INSR and Insr 1 0.05 0 0
170 INT71160 Positive_regulation of INSRR Positive_regulation of Binding of ANGPTL5 1 0.00 0.25 0
171 INT289672 Binding of GNRH1 and INSR 1 0.02 0 0
172 INT235623 Binding of INS and INSR 1 0.14 0.47 0
173 INT144754 Negative_regulation of Binding of Insr and Slc2a2 1 0.01 0 0
174 INT189678 Positive_regulation of CHKB Regulation of INSRR 1 0.00 0.06 0
175 INT277315 Binding of Insr and Mbnl1 1 0.18 1.1 0
176 INT225570 Ncoa6 Regulation of Sox9 1 0.16 0.72 0
177 INT114712 SRC Positive_regulation of Gene_expression of IGF1R 1 0.63 0.51 0
178 INT189686 CHKB Regulation of Negative_regulation of INSRR 1 0.00 0.46 0
179 INT315065 IGF1R Regulation of Gene_expression of PAR4 1 0.37 0.53 0
180 INT315049 IGF1R Regulation of MT1X 1 0.29 0.52 0
181 INT189705 INSRR Negative_regulation of Gene_expression of TERT 1 0.00 0.46 0
182 INT71159 Binding of INSRR and ANGPTL5 1 0.00 0.25 0
183 INT235624 INS Regulation of Phosphorylation of INSR 1 0.08 0.26 0
184 INT189697 INSRR Regulation of Gene_expression of TERT 1 0.00 0.46 0
185 INT233304 Binding of SRY and SLC22A8 1 0.34 0.93 0
186 INT202431 Binding of IGF2 and INSRR 1 0.01 0.85 0
187 INT156740 Binding of SRY and Srms 1 0.04 0 0
188 INT271281 Gene_expression of Stat1 Positive_regulation of Insr 1 0.19 0.51 0
189 INT189683 CHKB Negative_regulation of Negative_regulation of INSRR 1 0.00 0.46 0
190 INT271287 Gene_expression of IFNA1 Positive_regulation of Insr 1 0.03 0.51 0
191 INT189669 INSRR Regulation of TERT 1 0.00 0 0
192 INT308664 Akt1 Positive_regulation of Phosphorylation of Insr 1 0.02 0.43 0
193 INT144760 Binding of ABCA1 and Insr 1 0.00 0 0
194 INT319320 Binding of EGI and IGF1R 1 0.02 0.85 0
195 INT114713 Binding of IGF1R and SRC 1 0.33 0.6 0
196 INT342558 FGF9 Positive_regulation of MAPK3 1 0.03 1.21 0
197 INT102798 OPRM1 Regulation of INSRR 1 0.01 0 0
198 INT189672 Positive_regulation of INSRR Regulation of Transcription of TERT 1 0.00 0.23 0
199 INT342555 FGF9 Positive_regulation of MAPK1 1 0.07 1.22 0
200 INT218307 Grb10 Positive_regulation of Protein_catabolism of INSR 1 0.03 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for male sex determination. They are ordered first by their pain relevance and then by number of times they were reported in male sex determination. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6585 Positive_regulation of Insrr 110 0.52 40.67 89.9
2 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24
3 INT16654 Gene_expression of Insrr 138 0.46 58.96 75.68
4 INT4153 Binding of Insrr 109 0.40 17.99 72.15
5 INT31186 Negative_regulation of Insrr 81 0.37 24.91 55.94
6 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5
7 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59
8 INT12471 Regulation of Insrr 52 0.35 17.8 48.31
9 INT8691 Localization of Insr 85 0.80 9.27 30.32
10 INT5300 Regulation of Insr 54 0.60 11.33 29.26
11 INT9781 Binding of INSRR 64 0.31 19.1 25.2
12 INT9783 Gene_expression of INSRR 81 0.50 32.99 15.52
13 INT42979 Positive_regulation of INSRR 47 0.32 12.24 14.38
14 INT14768 Negative_regulation of Positive_regulation of Insr 16 0.56 5.51 13.59
15 INT110988 Gene_expression of Insr 58 0.42 42.12 12.18
16 INT50615 Positive_regulation of Positive_regulation of Insrr 11 0.19 5.5 10.05
17 INT33099 Negative_regulation of INSRR 32 0.40 13.82 9.85
18 INT20999 Negative_regulation of Binding of Insrr 17 0.47 3.53 8.93
19 INT132938 Phosphorylation of Insrr 21 0.03 10.55 8.88
20 INT12859 Localization of Insrr 16 0.32 2.68 8.07
21 INT30920 Positive_regulation of Gene_expression of Insr 14 0.66 2.91 7.32
22 INT36405 Positive_regulation of Insr 26 0.66 24.5 7.24
23 INT103878 Binding of PTGDR 9 0.48 6.22 7.23
24 INT62260 Negative_regulation of Gene_expression of Insrr 10 0.06 1.36 6.92
25 INT24622 Positive_regulation of Localization of Insr 15 0.69 0.32 6.85
26 INT12632 Negative_regulation of Binding of INSRR 13 0.38 6.54 6.39
27 INT12631 Positive_regulation of Binding of INSRR 11 0.45 6.13 6.04
28 INT32611 Phosphorylation of Insr 13 0.80 4.18 5.77
29 INT14769 Positive_regulation of Positive_regulation of Insr 10 0.43 2.66 5.55
30 INT9325 Gene_expression of Igf1r 14 0.77 8.74 5.48
31 INT83056 Transcription of Insrr 11 0.11 2.43 5.11
32 INT114058 Negative_regulation of Gene_expression of Insr 13 0.31 9.23 4.97
33 INT10115 Gene_expression of INSR 31 0.75 11.98 4.86
34 INT51392 Negative_regulation of Insr 18 0.27 14.75 4.84
35 INT12474 Regulation of INSRR 18 0.29 6.29 4.81
36 INT49564 Positive_regulation of PTGDR 8 0.70 3.28 4.62
37 INT24620 Negative_regulation of Gene_expression of Insr 14 0.39 6.98 4.61
38 INT55456 Regulation of Gene_expression of Insrr 9 0.03 3 4.24
39 INT51084 Binding of Insr 13 0.30 4.25 4.23
40 INT83035 Binding of INSR 16 0.47 9.29 4.11
41 INT25841 Regulation of Binding of Insrr 6 0.50 0.4 4.03
42 INT33332 Positive_regulation of Binding of Insrr 6 0.38 0.77 3.94
43 INT10116 Localization of INSR 11 0.57 5.43 3.48
44 INT14060 Negative_regulation of Negative_regulation of Insr 6 0.53 3.53 3.44
45 INT124736 Positive_regulation of Gene_expression of Insr 6 0.31 7.55 3.12
46 INT51178 Transcription of INSRR 9 0.17 2.09 3.09
47 INT33241 Localization of INSRR 10 0.10 1.24 3.08
48 INT95037 Negative_regulation of Regulation of Insrr 1 0.02 0 2.77
49 INT23527 Negative_regulation of Localization of Insr 10 0.39 2.58 2.5
50 INT86134 Gene_expression of Ptgdr 9 0.46 3.45 2.47
51 INT235399 Positive_regulation of Binding of PTGDR 2 0.15 1.08 2.33
52 INT83058 Regulation of Positive_regulation of Insrr 2 0.11 0.66 2.31
53 INT184932 Binding of Sry 1 0.31 2.57 2.28
54 INT147417 Positive_regulation of Gene_expression of Igf1r 3 0.46 1.69 2.2
55 INT24621 Regulation of Gene_expression of Insr 9 0.42 2.68 2.18
56 INT31006 Regulation of Localization of Insr 7 0.50 0.2 2.05
57 INT49569 Regulation of PTGDR 2 0.50 1.38 2.03
58 INT9336 Negative_regulation of Gene_expression of Igf1r 4 0.42 3.53 1.92
59 INT114059 Localization of Insr 10 0.46 3.49 1.87
60 INT51149 Positive_regulation of Gene_expression of INSRR 5 0.17 2.94 1.86
61 INT88518 Negative_regulation of Positive_regulation of INSRR 4 0.27 2.26 1.86
62 INT218303 Protein_catabolism of INSR 3 0.29 0.67 1.73
63 INT232645 Transcription of INSR 2 0.09 1.19 1.71
64 INT49563 Negative_regulation of PTGDR 3 0.57 1.79 1.61
65 INT89652 Phosphorylation of INSRR 4 0.01 1.36 1.6
66 INT114061 Regulation of Gene_expression of Insr 4 0.27 2.03 1.56
67 INT19342 Regulation of Insr 12 0.24 6.11 1.54
68 INT345367 Negative_regulation of Phosphorylation of Insrr 2 0.01 2.9 1.53
69 INT53273 Positive_regulation of Ptgdr 3 0.14 1.34 1.52
70 INT99694 Negative_regulation of Positive_regulation of Insrr 1 0.08 0.54 1.5
71 INT135920 Binding of SRY 9 0.45 3.57 1.45
72 INT125855 Regulation of Negative_regulation of Insrr 1 0.01 0.26 1.45
73 INT184933 Positive_regulation of Binding of Sry 1 0.42 1.23 1.42
74 INT49128 Gene_expression of IGF1R 35 0.63 23.48 1.39
75 INT184934 Positive_regulation of Sry 1 0.39 0.46 1.39
76 INT124738 Negative_regulation of Positive_regulation of Insr 5 0.23 3.73 1.24
77 INT9323 Transcription of Igf1r 2 0.63 1.08 1.23
78 INT10117 Positive_regulation of INSR 10 0.43 4.71 1.22
79 INT106339 Positive_regulation of Phosphorylation of Insr 1 0.49 0 1.12
80 INT127427 Negative_regulation of Ptgdr 1 0.17 1.66 1.12
81 INT16172 Protein_catabolism of Insrr 5 0.18 1.39 1.11
82 INT147416 Positive_regulation of Transcription of Igf1r 1 0.46 0.72 1.1
83 INT147415 Positive_regulation of Igf1r 2 0.43 0.97 1.09
84 INT32354 Negative_regulation of Regulation of Insr 3 0.33 0.13 1.08
85 INT72590 Regulation of Binding of INSRR 1 0.15 1.79 1.02
86 INT79889 Positive_regulation of Gene_expression of Insrr 4 0.24 1.01 1.01
87 INT171382 Phosphorylation of Insr 6 0.51 3.41 0.94
88 INT166715 Gene_expression of Sox9 16 0.65 6.39 0.92
89 INT12858 Negative_regulation of Localization of Insrr 2 0.18 0.26 0.92
90 INT41911 Regulation of Positive_regulation of Insr 2 0.21 0.32 0.88
91 INT171376 Positive_regulation of Phosphorylation of Insr 3 0.31 3.05 0.86
92 INT91908 Regulation of Negative_regulation of Insr 1 0.03 0.81 0.86
93 INT145306 Gene_expression of Sox9 5 0.54 2.47 0.8
94 INT100097 Negative_regulation of Transcription of Insrr 3 0.03 0.24 0.8
95 INT114714 Binding of IGF1R 8 0.36 5.26 0.78
96 INT144759 Regulation of Gene_expression of INSR 2 0.44 3.09 0.77
97 INT83057 Regulation of Transcription of Insrr 1 0.04 0.09 0.71
98 INT277207 Regulation of Ptgdr 1 0.08 1.17 0.7
99 INT117392 Binding of Insr 8 0.23 4.88 0.68
100 INT163543 Positive_regulation of Localization of INSRR 1 0.03 0 0.68
101 INT171366 Positive_regulation of Localization of Insr 3 0.18 0.63 0.66
102 INT277205 Localization of Ptgdr 2 0.22 1.74 0.65
103 INT18445 Regulation of Transcription of Insr 1 0.12 0.84 0.63
104 INT18446 Transcription of Insr 2 0.18 0.84 0.62
105 INT104877 Positive_regulation of Positive_regulation of Ptgdr 1 0.08 0.15 0.56
106 INT145859 Regulation of Gene_expression of Igf1r 1 0.59 1.58 0.55
107 INT235397 Positive_regulation of Negative_regulation of PTGDR 1 0.03 0.53 0.53
108 INT308979 Regulation of Localization of Insr 1 0.24 0.44 0.53
109 INT89654 Positive_regulation of Negative_regulation of INSRR 2 0.01 0.37 0.49
110 INT145304 Regulation of Gene_expression of Sox9 1 0.43 1.04 0.46
111 INT114062 Negative_regulation of Localization of Insr 1 0.19 0.31 0.39
112 INT69865 Binding of Ptgdr 2 0.08 1.25 0.38
113 INT168940 Phosphorylation of Igf1r 1 0.77 2.18 0.38
114 INT144755 Negative_regulation of INSR 5 0.41 2.09 0.36
115 INT267882 Positive_regulation of Phosphorylation of Insrr 2 0.01 0.71 0.32
116 INT24325 Regulation of SRY 2 0.24 0.89 0.32
117 INT99674 Regulation of Localization of Insrr 1 0.09 0.1 0.32
118 INT210766 Gene_expression of Igf1r 6 0.65 2.15 0.31
119 INT83030 Positive_regulation of Binding of INSR 2 0.49 2.35 0.31
120 INT132488 Positive_regulation of Localization of Insrr 1 0.07 0.35 0.3
121 INT70144 Gene_expression of Sry 4 0.63 1.15 0.28
122 INT278530 Regulation of Positive_regulation of Insr 1 0.01 1.96 0.28
123 INT192345 Positive_regulation of Phosphorylation of INSRR 1 0.01 0.68 0.27
124 INT124735 Positive_regulation of Positive_regulation of Insr 1 0.08 0 0.25
125 INT115253 Negative_regulation of Phosphorylation of Insr 1 0.27 0.56 0.25
126 INT250992 Regulation of Gene_expression of INSRR 2 0.00 1.22 0.24
127 INT145303 Regulation of Sox9 2 0.28 0.71 0.22
128 INT183683 Negative_regulation of Negative_regulation of Insrr 1 0.01 0.69 0.22
129 INT192958 Negative_regulation of IGF1R 8 0.30 6.35 0.21
130 INT250517 Phosphorylation of Igf1r 5 0.79 1.21 0.21
131 INT254040 Regulation of FGF9 2 0.57 1.04 0.21
132 INT213792 Positive_regulation of Igf1r 3 0.45 1 0.2
133 INT168938 Negative_regulation of Phosphorylation of Igf1r 1 0.40 1.1 0.19
134 INT277208 Positive_regulation of Gene_expression of Ptgdr 1 0.14 0.08 0.18
135 INT139662 Gene_expression of FGF9 7 0.65 2.26 0.17
136 INT168939 Negative_regulation of Igf1r 1 0.40 1.01 0.15
137 INT9320 Regulation of Transcription of Igf1r 1 0.04 0.36 0.13
138 INT95659 Negative_regulation of Gene_expression of INSRR 1 0.02 0.51 0.13
139 INT9333 Regulation of Igf1r 1 0.07 0.36 0.13
140 INT92590 Positive_regulation of Gene_expression of IGF1R 3 0.57 2.31 0.12
141 INT92634 Negative_regulation of Binding of Insr 1 0.25 0.08 0.12
142 INT211949 Negative_regulation of Sox9 1 0.31 0.83 0.12
143 INT92589 Positive_regulation of IGF1R 4 0.38 0.98 0.11
144 INT308981 Positive_regulation of Negative_regulation of Insr 1 0.27 0.95 0.11
145 INT323945 Positive_regulation of Binding of Insr 1 0.08 0.94 0.11
146 INT312954 Regulation of Binding of IGF1R 1 0.13 0 0.1
147 INT250519 Negative_regulation of Igf1r 5 0.42 2.7 0.09
148 INT211948 Regulation of Gene_expression of Sox9 2 0.33 0.94 0.08
149 INT92587 Positive_regulation of Positive_regulation of IGF1R 1 0.38 0.38 0.08
150 INT349623 Negative_regulation of Binding of Igf1r 1 0.39 0.51 0.08
151 INT250508 Negative_regulation of Gene_expression of Igf1r 1 0.42 2.01 0.08
152 INT349620 Binding of Igf1r 1 0.34 0.51 0.08
153 INT121678 Gene_expression of SRY 15 0.68 5.61 0.06
154 INT210242 Positive_regulation of Sox9 3 0.43 0.35 0.06
155 INT234462 Phosphorylation of IGF1R 2 0.42 0.99 0.06
156 INT233311 Positive_regulation of Gene_expression of SRY 1 0.41 0.61 0.06
157 INT211939 Regulation of Sox9 1 0.33 0.35 0.06
158 INT315099 Localization of IGF1R 2 0.55 0.36 0.04
159 INT184013 Protein_catabolism of Insr 1 0.05 0.4 0.04
160 INT189730 Negative_regulation of Negative_regulation of INSRR 3 0.01 0.09 0.03
161 INT225365 Binding of Sox9 2 0.28 0.48 0.03
162 INT207727 Positive_regulation of SRY 2 0.56 1.94 0.03
163 INT145302 Positive_regulation of Sox9 2 0.48 1.42 0.03
164 INT156739 Localization of SRY 2 0.75 3.21 0.03
165 INT234471 Negative_regulation of Phosphorylation of IGF1R 1 0.04 0.76 0.03
166 INT261550 Regulation of Positive_regulation of INSRR 1 0.00 0 0.03
167 INT117362 Positive_regulation of Positive_regulation of INSR 1 0.22 0.1 0.03
168 INT334692 Localization of Igf1r 1 0.09 0.89 0.03
169 INT235634 Phosphorylation of INSR 24 0.70 3.64 0
170 INT222308 Regulation of IGF1R 3 0.12 2.18 0
171 INT211945 Negative_regulation of Gene_expression of Sox9 3 0.44 0.63 0
172 INT339214 Negative_regulation of Gene_expression of IGF1R 2 0.22 0.4 0
173 INT282728 Regulation of Igf1r 2 0.18 0.92 0
174 INT215947 Positive_regulation of Gene_expression of INSR 2 0.14 0.25 0
175 INT207734 Negative_regulation of SRY 2 0.28 0.77 0
176 INT273600 Positive_regulation of FGF9 2 0.15 1.46 0
177 INT342561 Negative_regulation of FGF9 1 0.09 0.78 0
178 INT322883 Regulation of Transcription of Sox9 1 0.43 0.18 0
179 INT321694 Positive_regulation of Phosphorylation of Igf1r 1 0.27 0.2 0
180 INT338259 Positive_regulation of Binding of IGF1R 1 0.27 1.38 0
181 INT139665 Transcription of FGF9 1 0.04 0.11 0
182 INT144758 Negative_regulation of Negative_regulation of INSR 1 0.41 0 0
183 INT319333 Transcription of IGF1R 1 0.31 0.85 0
184 INT321704 Positive_regulation of Positive_regulation of Igf1r 1 0.18 0.17 0
185 INT235628 Negative_regulation of Phosphorylation of INSR 1 0.16 0.25 0
186 INT211943 Transcription of Sox9 1 0.50 0.3 0
187 INT230481 Positive_regulation of Regulation of Insr 1 0.01 0.24 0
188 INT233314 Positive_regulation of Binding of SRY 1 0.41 0.28 0
189 INT144756 Positive_regulation of Negative_regulation of INSR 1 0.49 0 0
190 INT342565 Localization of FGF9 1 0.16 0.79 0
191 INT144757 Negative_regulation of Gene_expression of INSR 1 0.41 0 0
192 INT227421 Negative_regulation of Gene_expression of Sry 1 0.07 0 0
193 INT322886 Transcription of Sox9 1 0.50 0.25 0
194 INT145307 Positive_regulation of Positive_regulation of Sox9 1 0.48 0.07 0
195 INT233309 Regulation of Localization of SRY 1 0.37 0.33 0
196 INT233312 Phosphorylation of SRY 1 0.66 0.73 0
197 INT227425 Localization of Sry 1 0.12 0 0
198 INT342569 Positive_regulation of Gene_expression of FGF9 1 0.11 1.05 0
199 INT139659 Binding of FGF9 1 0.02 0.13 0
200 INT352010 Protein_catabolism of Sox9 1 0.22 0.07 0
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