GO:0030903

Name notochord development Categary Process Go Slim No Go Link GO:0030903

Unique Molecular Interactions 51 Total Molecular Interactions 62 Total Single Events 721 Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for notochord development. They are ordered first by their pain relevance and then by number of times they were reported for notochord development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT287104	Binding of Ntrk2 and T	1	0.20	3.29	1.26
2	INT59396	Tead1 Negative_regulation of Negative_regulation of Man2a2	1	0.00	0	0.86
3	INT59395	Tead1 Negative_regulation of Man2a2	1	0.00	0	0.86
4	INT287099	Binding of Bdnf and T	1	0.10	1.1	0.69
5	INT88142	Pt Positive_regulation of 1700061J05Rik	1	0.04	1.08	0.66
6	INT202043	MMP13 Regulation of Protein_catabolism of COL2A1	1	0.01	0.54	0.54
7	INT135755	Pomc Positive_regulation of Positive_regulation of Id3	1	0.17	0	0.5
8	INT135752	Pomc Positive_regulation of Id3	1	0.16	0	0.5
9	INT312122	ELANE Positive_regulation of Protein_catabolism of COL2A1	1	0.05	0.65	0.39
10	INT204793	T Positive_regulation of Mthfd1	1	0.00	1.32	0.39
11	INT340609	Bdnf Regulation of Gene_expression of Wnt3a	1	0.53	0.31	0.36
12	INT264523	PTGDS Positive_regulation of Gene_expression of COL2A1	1	0.03	1.24	0.3
13	INT220194	PTGER2 Negative_regulation of COL2A1	1	0.26	0.55	0.29
14	INT287098	Binding of FL and T	1	0.10	0.66	0.23
15	INT60347	COL2A1 Positive_regulation of Gene_expression of Hras	1	0.05	0.92	0.2
16	INT287097	T Positive_regulation of Ntrk2	1	0.21	0.6	0.19
17	INT220190	PTGER2 Regulation of COL2A1	1	0.32	0.92	0.18
18	INT220191	Binding of COL2A1 and PTGER2	1	0.22	0.35	0.18
19	INT30068	Tead1 Positive_regulation of Localization of Avp	1	0.04	0	0.16
20	INT340608	Binding of Creb1 and Wnt3a	1	0.30	0.24	0.14
21	INT293867	Binding of COL2A1 and MEFV	1	0.01	0.52	0.14
22	INT220213	Mmp13 Regulation of Protein_catabolism of COL2A1	1	0.49	0.29	0.14
23	INT226532	T Positive_regulation of Gene_expression of IFNA1	1	0.01	0.15	0.12
24	INT326974	BMP2 Positive_regulation of Gene_expression of COL2A1	1	0.07	0.27	0.11
25	INT220195	PTGER2 Negative_regulation of Localization of COL2A1	1	0.26	0.51	0.09
26	INT288003	Binding of COL2A1 and PADI1	1	0.09	0.11	0.06
27	INT220189	Binding of COL2A1 and TIMP1	1	0.04	0.1	0.05
28	INT306238	Tead1 Regulation of Ins1	1	0.00	1.04	0.05
29	INT323807	NFAT5 Regulation of Gene_expression of COL2A1	1	0.29	0.19	0.04
30	INT220196	Binding of PTGER2 and Negative_regulation of Gene_expression of COL2A1	1	0.26	0.77	0.04
31	INT184208	IL1B Negative_regulation of SOX9	1	0.32	0	0.03
32	INT233397	Binding of ABCA4 and COL2A1	1	0.38	3.59	0.03
33	INT220245	IL1RN Regulation of Protein_catabolism of COL2A1	1	0.09	0	0.03
34	INT293869	Binding of COL2A1 and GREM1	1	0.00	1.11	0
35	INT320029	Gene_expression of SOX9 Positive_regulation of Gene_expression of COL7A1	1	0.03	0	0
36	INT245726	SOX9 Regulation of SGCG	1	0.00	0.29	0
37	INT333879	Shc1 Positive_regulation of SOX9	1	0.01	0	0
38	INT251072	Wnt3a Positive_regulation of Axin2	1	0.23	0.29	0
39	INT288002	Binding of COL2A1 and GOPC	1	0.12	0	0
40	INT312230	INPP5K Regulation of Gene_expression of COL2A1	1	0.06	0	0
41	INT326893	Binding of Tcf4 and Wnt3a	1	0.13	0	0
42	INT326896	Wnt3a Positive_regulation of Transcription of PLD2	1	0.24	0.06	0
43	INT88567	COL2A1 Positive_regulation of A1cf	1	0.09	0.36	0
44	INT312227	INPP5K Regulation of Negative_regulation of COL2A1	1	0.06	0	0
45	INT251070	Wnt3a Positive_regulation of Cldn3	1	0.30	0.29	0
46	INT326894	Wnt3a Positive_regulation of Transcription of Pld1	1	0.24	0.06	0
47	INT312345	Binding of COL2A1 and COL5A2	1	0.00	1.21	0
48	INT323804	NFAT5 Regulation of Transcription of COL2A1	1	0.43	0.07	0
49	INT312213	INPP5K Regulation of COL2A1	1	0.06	0	0
50	INT249606	Slc25a1 Positive_regulation of Sd	1	0.05	0	0
51	INT245735	SOX9 Regulation of COL5A2	1	0.07	0.29	0

Single Events

The table below shows the top 100 pain related interactions that have been reported for notochord development. They are ordered first by their pain relevance and then by number of times they were reported in notochord development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT11659	Gene_expression of COL2A1	164	0.78	78.49	22.58
2	INT130731	Protein_catabolism of COL2A1	47	0.96	21.86	9.28
3	INT340600	Gene_expression of Wnt3a	1	0.68	2.14	9.14
4	INT20552	Negative_regulation of Gene_expression of COL2A1	29	0.56	11.92	4.81
5	INT204449	Gene_expression of T	17	0.32	9.77	4.77
6	INT217742	Positive_regulation of Gene_expression of COL2A1	20	0.67	9.76	4.23
7	INT340603	Regulation of Gene_expression of Wnt3a	1	0.54	0.49	3.75
8	INT53021	Positive_regulation of COL2A1	29	0.55	27.75	3.47
9	INT130729	Negative_regulation of Protein_catabolism of COL2A1	15	0.42	7.59	3.35
10	INT340595	Positive_regulation of Gene_expression of Wnt3a	1	0.61	0.86	3.11
11	INT20551	Negative_regulation of COL2A1	31	0.55	21.98	2.66
12	INT96693	Binding of COL2A1	45	0.46	37.11	2.61
13	INT53434	Positive_regulation of T	7	0.07	3.67	2.09
14	INT39783	Positive_regulation of Sd	3	0.36	0.41	1.86
15	INT340596	Negative_regulation of Gene_expression of Wnt3a	1	0.51	0.38	1.4
16	INT39781	Gene_expression of Sd	7	0.60	2.47	1.33
17	INT117232	Localization of COL2A1	11	0.72	7.34	1.3
18	INT134663	Gene_expression of SOX9	40	0.75	9.07	1.2
19	INT226407	Negative_regulation of T	2	0.21	1.81	1.18
20	INT11658	Regulation of Gene_expression of COL2A1	9	0.62	3.09	1.11
21	INT33207	Gene_expression of Pt	9	0.53	0.93	1.08
22	INT208427	Regulation of T	3	0.25	3.28	1.08
23	INT340604	Regulation of Wnt3a	1	0.24	0	0.95
24	INT287093	Positive_regulation of Gene_expression of T	1	0.28	1.47	0.86
25	INT287090	Regulation of Gene_expression of T	1	0.18	2.77	0.86
26	INT42339	Gene_expression of Tead1	4	0.31	0.56	0.8
27	INT287094	Transcription of T	1	0.29	1.41	0.8
28	INT66992	Positive_regulation of Id3	2	0.43	0.23	0.78
29	INT57881	Binding of Tead1	2	0.25	1.63	0.7
30	INT226411	Binding of T	2	0.15	1.56	0.68
31	INT31653	Positive_regulation of Tead1	4	0.47	0.25	0.66
32	INT184222	Negative_regulation of SOX9	7	0.41	2.68	0.58
33	INT157103	Transcription of SOX9	6	0.59	1.2	0.58
34	INT157104	Positive_regulation of SOX9	6	0.66	1.66	0.52
35	INT157105	Positive_regulation of Transcription of SOX9	4	0.58	0.88	0.51
36	INT135747	Gene_expression of Id3	1	0.52	0	0.5
37	INT340598	Binding of Wnt3a	1	0.33	0.15	0.46
38	INT9732	Regulation of COL2A1	9	0.58	6.93	0.44
39	INT287095	Negative_regulation of Gene_expression of T	1	0.24	0.47	0.41
40	INT340606	Positive_regulation of Wnt3a	1	0.61	0.49	0.4
41	INT180577	Positive_regulation of Protein_catabolism of COL2A1	2	0.12	0.91	0.31
42	INT29080	Binding of Pt	1	0.03	0.09	0.31
43	INT220209	Negative_regulation of Localization of COL2A1	1	0.41	0.48	0.29
44	INT51514	Positive_regulation of Wnt3a	3	0.04	3.32	0.28
45	INT29305	Positive_regulation of Pt	6	0.37	0.73	0.27
46	INT245763	Regulation of SOX9	4	0.43	1.68	0.21
47	INT70176	Negative_regulation of Sd	1	0.05	0.28	0.21
48	INT134662	Positive_regulation of Gene_expression of SOX9	9	0.48	1.69	0.19
49	INT90480	Negative_regulation of Tead1	4	0.37	1.37	0.18
50	INT220208	Regulation of Protein_catabolism of COL2A1	1	0.26	0.28	0.17
51	INT309524	Regulation of Pt	1	0.05	0	0.16
52	INT51512	Negative_regulation of Positive_regulation of Wnt3a	1	0.04	1.3	0.13
53	INT51513	Positive_regulation of Positive_regulation of Wnt3a	1	0.04	1.31	0.13
54	INT221000	Phosphorylation of COL2A1	1	0.19	0.18	0.12
55	INT309526	Negative_regulation of Gene_expression of Pt	1	0.05	0	0.11
56	INT309525	Regulation of Gene_expression of Pt	1	0.05	0	0.11
57	INT184220	Negative_regulation of Gene_expression of SOX9	4	0.36	0.58	0.09
58	INT214463	Binding of Wnt3a	2	0.26	0.23	0.08
59	INT250505	Positive_regulation of Negative_regulation of COL2A1	1	0.41	0.57	0.05
60	INT272249	Negative_regulation of Negative_regulation of COL2A1	1	0.06	0	0.05
61	INT69474	Protein_catabolism of T	1	0.64	0	0.04
62	INT313405	Positive_regulation of Localization of Pt	1	0.19	0	0.03
63	INT249932	Negative_regulation of Pt	1	0.08	0.1	0.03
64	INT342197	Transcription of Pt	1	0.54	0.3	0.03
65	INT313411	Localization of Pt	1	0.29	0	0.03
66	INT342203	Negative_regulation of Transcription of Pt	1	0.33	0.3	0.03
67	INT214538	Binding of Sd	6	0.26	1.31	0
68	INT184729	Transcription of COL2A1	4	0.67	1.1	0
69	INT162339	Regulation of Gene_expression of SOX9	4	0.32	0.42	0
70	INT245757	Localization of SOX9	4	0.62	0.8	0
71	INT214465	Localization of Wnt3a	2	0.52	0.29	0
72	INT251053	Gene_expression of Wnt3a	2	0.47	0.5	0
73	INT165862	Positive_regulation of Binding of COL2A1	2	0.43	0	0
74	INT326853	Positive_regulation of Gene_expression of Wnt3a	1	0.36	0.2	0
75	INT312246	Regulation of Negative_regulation of COL2A1	1	0.07	0	0
76	INT306234	Localization of Tead1	1	0.01	0.22	0
77	INT251054	Regulation of Localization of Wnt3a	1	0.27	0.07	0
78	INT323815	Negative_regulation of Transcription of SOX9	1	0.41	0.18	0
79	INT245752	Positive_regulation of Binding of SOX9	1	0.41	0.48	0
80	INT251066	Regulation of Gene_expression of Wnt3a	1	0.31	0.07	0
81	INT322897	Negative_regulation of Transcription of COL2A1	1	0.17	0	0
82	INT281642	Localization of Sd	1	0.26	0	0
83	INT245765	Binding of SOX9	1	0.31	0.87	0
84	INT312245	Positive_regulation of Localization of SOX9	1	0.10	0	0
85	INT326843	Negative_regulation of Gene_expression of Wnt3a	1	0.22	0.29	0