GO:0030984

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Name kininogen binding
Categary Function
Go Slim No
Go Link GO:0030984
Unique Molecular Interactions 44
Total Molecular Interactions 58
Total Single Events 408
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for kininogen binding. They are ordered first by their pain relevance and then by number of times they were reported for kininogen binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7190 Syt17 Positive_regulation of Ctsb 1 0.16 0 3.23
2 INT7193 Abl2 Positive_regulation of Ctsb 1 0.21 0 3.21
3 INT7195 Negative_regulation of Syt17 Positive_regulation of Ctsb 1 0.10 0 2.25
4 INT7186 Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
5 INT7184 Negative_regulation of Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
6 INT7191 Negative_regulation of Abl2 Positive_regulation of Ctsb 1 0.13 0 1.04
7 INT90385 EXTL3 Regulation of Ctsl 1 0.00 1.1 0.98
8 INT335644 CTSB Positive_regulation of F2RL1 1 0.02 2.58 0.82
9 INT141605 Gene_expression of Ctsl Positive_regulation of Positive_regulation of MET 1 0.34 0 0.8
10 INT333544 CTSB Regulation of Protein_catabolism of APP 1 0.01 0.53 0.62
11 INT333543 CTSB Regulation of APP 1 0.01 0.53 0.62
12 INT36320 PDYN Negative_regulation of Ctsb 1 0.00 0 0.61
13 INT118485 CST3 Regulation of CTSH 1 0.36 0 0.49
14 INT165078 Binding of CTSB and Notch1 1 0.00 1.08 0.48
15 INT139873 Negative_regulation of CTSB Negative_regulation of Gene_expression of App 1 0.00 0.8 0.41
16 INT335643 CTSB Positive_regulation of PAR4 1 0.01 1.3 0.41
17 INT139874 CTSB Negative_regulation of Gene_expression of App 1 0.00 0.8 0.41
18 INT28688 Binding of Kng1 and Ctsl1 1 0.15 0 0.31
19 INT135095 Negative_regulation of CTSB Negative_regulation of APP 1 0.00 0.74 0.3
20 INT50107 Ei24 Positive_regulation of Localization of CTSB 3 0.00 0.6 0.29
21 INT258858 CTSB Positive_regulation of Gene_expression of IL8 1 0.00 0.64 0.28
22 INT139980 Negative_regulation of CTSB Negative_regulation of Gene_expression of APP 1 0.15 0.7 0.26
23 INT139981 CTSB Negative_regulation of Gene_expression of APP 1 0.11 0.7 0.26
24 INT245183 Binding of CTSB and TCF7L2 1 0.39 6.39 0.18
25 INT199128 Ctsb Positive_regulation of Prss1 1 0.02 0.9 0.15
26 INT199129 Ctsb Positive_regulation of PRSS1 1 0.01 0.9 0.15
27 INT321578 Binding of Plaur and Positive_regulation of Ctsb 1 0.15 0.92 0.12
28 INT171645 Negative_regulation of CTSB Positive_regulation of PRSS1 1 0.44 0.36 0.1
29 INT171644 CTSB Positive_regulation of PRSS1 1 0.52 0.36 0.1
30 INT171648 Binding of CTSB and PRSS1 1 0.27 0.42 0.1
31 INT62030 Bche Regulation of Localization of CTSB 1 0.09 0.15 0.06
32 INT110967 REG1A Positive_regulation of Gene_expression of CTSB 1 0.01 0 0.04
33 INT278408 Hps5 Positive_regulation of Localization of Ctsb 1 0.05 0.11 0.03
34 INT354622 CTSB Regulation of PRDX5 1 0.00 0.38 0
35 INT321580 Plaur Regulation of Ctsb 1 0.09 0.53 0
36 INT278369 Ctsb Positive_regulation of Casp1 1 0.03 0 0
37 INT278384 Il1 Negative_regulation of Ctsb 1 0.01 0.12 0
38 INT322536 Negative_regulation of Ctsb Positive_regulation of Gene_expression of Cdkn1b 1 0.02 0.3 0
39 INT278399 Syk Positive_regulation of Localization of Ctsb 1 0.09 0.28 0
40 INT322537 Ctsb Regulation of Gene_expression of Cdkn1b 1 0.01 0.1 0
41 INT171647 CTSB Positive_regulation of NXF1 1 0.23 0.47 0
42 INT278392 Syk Regulation of Positive_regulation of Ctsb 1 0.06 0 0
43 INT322539 Ctsb Regulation of Cdkn1b 1 0.03 0.19 0
44 INT331090 Binding of Ctsl and Itga2 1 0.10 0.2 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for kininogen binding. They are ordered first by their pain relevance and then by number of times they were reported in kininogen binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT3623 Negative_regulation of CTSB 49 0.55 27.39 13.52
2 INT47301 Gene_expression of Ctsl 27 0.76 7.72 9.32
3 INT3622 Regulation of CTSB 34 0.58 16.08 8.76
4 INT7168 Positive_regulation of Ctsb 9 0.70 0.3 7.58
5 INT50105 Localization of CTSB 29 0.78 10.98 5.21
6 INT7170 Positive_regulation of Positive_regulation of Ctsb 1 0.40 0 4.76
7 INT47298 Localization of Ctsl 13 0.79 3.77 4.08
8 INT20265 Gene_expression of Ctsb 3 0.47 1.01 3.52
9 INT110980 Gene_expression of CTSB 17 0.45 8.02 2.69
10 INT73028 Positive_regulation of Transcription of Ctsb 1 0.55 1.53 2.54
11 INT59135 Positive_regulation of CTSB 15 0.67 7.53 2.53
12 INT37427 Positive_regulation of Gene_expression of Ctsb 2 0.37 1.02 2.33
13 INT7173 Regulation of Positive_regulation of Ctsb 1 0.49 0 2.29
14 INT47303 Regulation of Ctsl 10 0.56 2.64 2.04
15 INT58208 Negative_regulation of Ctsl 8 0.53 3.49 1.91
16 INT47302 Regulation of Gene_expression of Ctsl 2 0.53 0.54 1.77
17 INT50106 Positive_regulation of Localization of CTSB 9 0.33 3.15 1.69
18 INT73027 Transcription of Ctsb 1 0.56 1.01 1.68
19 INT42335 Binding of CTSB 11 0.34 5.98 1.37
20 INT47305 Positive_regulation of Gene_expression of Ctsl 5 0.59 2.06 1.12
21 INT20317 Localization of Ctsb 3 0.81 0.68 1.12
22 INT59136 Negative_regulation of Positive_regulation of CTSB 3 0.41 2.02 1.11
23 INT6534 Negative_regulation of Ctsl1 3 0.54 0.11 0.94
24 INT7175 Negative_regulation of Positive_regulation of Ctsb 1 0.34 0 0.86
25 INT120046 Negative_regulation of Localization of Ctsl 2 0.40 0.31 0.8
26 INT79243 Negative_regulation of Localization of CTSB 2 0.57 1.35 0.73
27 INT20318 Regulation of Ctsb 1 0.54 0.19 0.69
28 INT126164 Positive_regulation of Ctsb 15 0.49 3.34 0.63
29 INT59137 Protein_catabolism of CTSB 5 0.96 3.92 0.62
30 INT28687 Gene_expression of Ctsl1 4 0.61 0.48 0.57
31 INT51843 Localization of Ctsl1 3 0.62 0.54 0.54
32 INT126367 Positive_regulation of Gene_expression of CTSB 3 0.04 1.57 0.52
33 INT160148 Positive_regulation of Ctsl 2 0.43 0.74 0.52
34 INT193736 Regulation of Positive_regulation of CTSB 1 0.04 1.13 0.52
35 INT36603 Positive_regulation of CTSH 1 0.01 0 0.46
36 INT6533 Binding of Ctsl1 2 0.34 0 0.45
37 INT348083 Positive_regulation of Ctsl1 1 0.08 0.21 0.4
38 INT224637 Protein_catabolism of Ctsl 1 0.12 0.76 0.37
39 INT6536 Negative_regulation of Binding of Ctsl1 1 0.39 0 0.3
40 INT126366 Regulation of Binding of CTSB 1 0.01 0.31 0.28
41 INT36060 Protein_catabolism of Ctsl1 2 0.83 0.15 0.22
42 INT124178 Regulation of Ctsl1 1 0.23 0.19 0.22
43 INT220862 Negative_regulation of Transcription of Ctsl 1 0.05 0.41 0.21
44 INT220859 Transcription of Ctsl 1 0.09 0.41 0.21
45 INT235549 Gene_expression of Ctsb 19 0.58 8.61 0.2
46 INT45092 Positive_regulation of Localization of Ctsb 1 0.50 0 0.19
47 INT142708 Gene_expression of CTSH 1 0.75 1.51 0.18
48 INT47304 Regulation of Localization of Ctsl 1 0.23 0.14 0.15
49 INT348081 Positive_regulation of Gene_expression of Ctsl1 1 0.06 0.24 0.14
50 INT47300 Negative_regulation of Gene_expression of Ctsl 1 0.57 0.14 0.14
51 INT321564 Positive_regulation of Protein_catabolism of Ctsb 1 0.16 0.92 0.12
52 INT47299 Positive_regulation of Localization of Ctsl 1 0.40 0.15 0.12
53 INT321559 Regulation of Protein_catabolism of Ctsb 1 0.10 0.89 0.11
54 INT36061 Negative_regulation of Protein_catabolism of Ctsl1 1 0.12 0.08 0.1
55 INT62029 Regulation of Localization of CTSB 2 0.05 0.21 0.09
56 INT55785 Negative_regulation of Localization of Ctsb 1 0.23 0.51 0.07
57 INT321566 Protein_catabolism of Ctsb 2 0.23 1.07 0.06
58 INT180694 Regulation of Localization of Ctsl1 1 0.16 0 0.05
59 INT278321 Localization of Ctsb 1 0.14 0.67 0.03
60 INT278345 Positive_regulation of Positive_regulation of Ctsb 1 0.09 0.82 0.03
61 INT321548 Negative_regulation of Ctsb 7 0.21 8.92 0
62 INT278332 Regulation of Ctsb 3 0.22 2.06 0
63 INT278342 Positive_regulation of Localization of Ctsb 1 0.09 0 0
64 INT322504 Regulation of Gene_expression of Ctsb 1 0.06 0.69 0
65 INT171654 Regulation of Regulation of CTSB 1 0.18 0.18 0
66 INT322509 Positive_regulation of Gene_expression of Ctsb 1 0.09 1.26 0
67 INT278325 Negative_regulation of Positive_regulation of Ctsb 1 0.08 0 0
68 INT321556 Negative_regulation of Transcription of Ctsb 1 0.15 0.18 0
69 INT321544 Transcription of Ctsb 1 0.25 0.18 0
70 INT322514 Negative_regulation of Gene_expression of Ctsb 1 0.05 0.08 0
71 INT278352 Regulation of Positive_regulation of Ctsb 1 0.08 0 0
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