GO:0031639

From wiki-pain
Revision as of 15:02, 23 January 2013 by Daniel (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Name plasminogen activation
Categary Process
Go Slim No
Go Link GO:0031639
Unique Molecular Interactions 123
Total Molecular Interactions 211
Total Single Events 896
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for plasminogen activation. They are ordered first by their pain relevance and then by number of times they were reported for plasminogen activation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69057 H2-M3 Regulation of Klkb1 1 0.00 0.42 2.71
2 INT24689 Binding of PLAT and Serpine1 1 0.00 3.77 1.64
3 INT141907 F2r Regulation of Plat 1 0.46 0 1.59
4 INT105112 Plat Positive_regulation of JUN 1 0.01 1.55 1.58
5 INT18659 Plat Regulation of ZC3H12D 1 0.02 0.1 1.29
6 INT101715 PLAT Positive_regulation of NFKB1 2 0.11 0.99 1.09
7 INT105113 Plat Positive_regulation of NFKB1 1 0.03 1.06 1.06
8 INT125523 PLAT Positive_regulation of GDF15 1 0.13 1.33 0.75
9 INT14178 DHCR24 Positive_regulation of Localization of PDYN 1 0.05 0 0.72
10 INT14177 DHCR24 Positive_regulation of PDYN 1 0.05 0 0.71
11 INT124257 Plat Positive_regulation of Jun 5 0.12 3.33 0.67
12 INT101718 PLAT Positive_regulation of Transcription of OPRM1 1 0.22 0.06 0.61
13 INT101719 PLAT Positive_regulation of NFYC 1 0.13 0.1 0.6
14 INT101717 PLAT Positive_regulation of JUND 1 0.17 0.1 0.59
15 INT207504 Binding of ap and Klkb1 1 0.13 0 0.58
16 INT37034 PLAT Positive_regulation of PLDN 1 0.08 0.15 0.58
17 INT37035 PLAT Negative_regulation of ODC1 1 0.45 0.15 0.58
18 INT145718 Positive_regulation of Plat Positive_regulation of Bdnf 1 0.20 0 0.56
19 INT105111 Negative_regulation of Plat Positive_regulation of NFKB1 1 0.03 0.53 0.54
20 INT49358 Binding of DHCR24 and Pdyn 1 0.00 0 0.53
21 INT180958 Binding of F13A1 and PLAT 2 0.03 2.16 0.47
22 INT22674 Binding of SERPINE1 and PLAT 7 0.04 0.65 0.45
23 INT353631 Oas1a Positive_regulation of Klkb1 1 0.00 0 0.44
24 INT96615 Binding of F11 and Nrcam 1 0.12 0.52 0.43
25 INT125520 PLAT Positive_regulation of Gene_expression of GDF15 1 0.13 0.74 0.42
26 INT132730 Plat Positive_regulation of Il6 1 0.08 0.76 0.41
27 INT132729 Plat Positive_regulation of Il1b 1 0.09 0.76 0.41
28 INT124260 Plat Positive_regulation of Mapk1 1 0.14 0.81 0.41
29 INT214854 SERPINE1 Positive_regulation of PLAT 1 0.24 0.42 0.33
30 INT93896 Plat Positive_regulation of Gtf3a 1 0.00 0.51 0.32
31 INT124259 Negative_regulation of Plat Positive_regulation of Jun 4 0.11 1.74 0.31
32 INT15685 Binding of PLAT and Serpine1 3 0.36 1.01 0.31
33 INT142286 Binding of PLG and Plat 2 0.52 0.7 0.31
34 INT207502 Positive_regulation of Binding of ap and Klkb1 1 0.18 0 0.31
35 INT207503 Binding of Klkb1 and Scn7a 1 0.02 0 0.3
36 INT247083 Binding of F5 and PLAT 1 0.03 0.88 0.29
37 INT44759 Negative_regulation of PLAT Positive_regulation of ODC1 1 0.27 0 0.27
38 INT44760 PLAT Positive_regulation of ODC1 1 0.29 0 0.27
39 INT207505 Negative_regulation of Binding of ap and Klkb1 1 0.15 0 0.26
40 INT125522 PLAT Regulation of Gene_expression of GDF15 1 0.08 0.46 0.26
41 INT125513 PLAT Positive_regulation of Transcription of GDF15 1 0.12 0.44 0.26
42 INT348755 Plat Regulation of Gene_expression of Cldn5 1 0.10 0.45 0.25
43 INT125517 Negative_regulation of PLAT Positive_regulation of GDF15 1 0.12 0.46 0.25
44 INT125519 Regulation of PLAT Positive_regulation of NFKB1 1 0.07 0.44 0.24
45 INT273055 Plat Positive_regulation of Gene_expression of Nos2 1 0.01 1.34 0.23
46 INT37033 PLAT Negative_regulation of PLDN 1 0.08 0.07 0.23
47 INT270433 PLAT Positive_regulation of Positive_regulation of Gsk3b 1 0.04 0.5 0.21
48 INT124262 Negative_regulation of Plat Positive_regulation of Mapk1 1 0.13 0.41 0.21
49 INT124263 Plat Positive_regulation of Gene_expression of Cpox 1 0.07 0.42 0.21
50 INT135463 Binding of DHCR24 and Fos 1 0.35 0.17 0.19
51 INT135462 Binding of DHCR24 and Cfp 1 0.00 0.17 0.18
52 INT247082 Binding of PLAT and PTBP1 1 0.14 0.59 0.18
53 INT259934 Plat Positive_regulation of Gene_expression of Mmp9 2 0.33 1.05 0.17
54 INT25945 Plat Regulation of App 1 0.15 0.25 0.17
55 INT25947 Plat Regulation of Transcription of App 1 0.15 0.25 0.17
56 INT266899 Binding of Prkca and Plat 1 0.02 0.57 0.17
57 INT277013 PLAT Positive_regulation of Gene_expression of F13A1 1 0.02 0.31 0.17
58 INT172674 Ptpn6 Negative_regulation of Gene_expression of Plat 1 0.02 1.3 0.16
59 INT294207 Serpine1 Regulation of Gene_expression of Plat 1 0.50 0.92 0.16
60 INT270416 PLAT Negative_regulation of Positive_regulation of PLG 1 0.00 0.48 0.15
61 INT248147 PLAT Positive_regulation of Gene_expression of CPOX 1 0.00 0.51 0.15
62 INT188249 PLAT Positive_regulation of PLG 2 0.10 0.86 0.14
63 INT180671 Binding of Plat and Regulation of Serpine1 1 0.16 0.06 0.14
64 INT311733 Plat Regulation of Protein_catabolism of Orai1 1 0.28 0.71 0.13
65 INT311727 Plat Regulation of Protein_catabolism of Col17a1 1 0.31 0.71 0.13
66 INT311737 Plat Regulation of Positive_regulation of Fcgr2b 1 0.31 0.71 0.13
67 INT311731 Plat Regulation of Protein_catabolism of Pik3cd 1 0.31 0.71 0.13
68 INT294208 Gene_expression of Serpine1 Negative_regulation of Plat 1 0.47 0.94 0.12
69 INT266904 Plat Positive_regulation of Positive_regulation of Mapk8 1 0.03 0.6 0.11
70 INT22670 PLAT Positive_regulation of SERPINE1 1 0.03 0.1 0.1
71 INT311734 Binding of Plat and Slpi 1 0.20 0.64 0.1
72 INT3562 Trh Positive_regulation of Klkb1 1 0.10 0 0.1
73 INT311725 Binding of Plat and Mmp9 1 0.36 0.64 0.1
74 INT311739 Binding of SELL and Plat 1 0.41 0.63 0.1
75 INT311735 Binding of Plat and Fcgr2b 1 0.29 0.65 0.1
76 INT22672 Positive_regulation of Binding of SERPINE1 and PLAT 1 0.03 0.1 0.1
77 INT19922 Binding of F13A1 and Plat 1 0.01 0.46 0.1
78 INT311738 Binding of Anxa1 and Plat 1 0.19 0.63 0.1
79 INT44591 PLAT Negative_regulation of CNOT4 1 0.10 0.33 0.1
80 INT64087 Plat Positive_regulation of Gene_expression of Penk 1 0.25 0 0.08
81 INT294218 INCENP Positive_regulation of Plat 1 0.00 0.4 0.08
82 INT64086 Positive_regulation of Plat Regulation of Penk 1 0.25 0 0.07
83 INT247079 Gene_expression of PLAT Positive_regulation of Gene_expression of PLG 1 0.36 0.3 0.07
84 INT259931 Plat Positive_regulation of Gene_expression of Jun 1 0.08 0.58 0.07
85 INT64088 Plat Regulation of Penk 1 0.15 0 0.07
86 INT344719 Hdl1 Positive_regulation of Plat 1 0.10 1.23 0.05
87 INT259928 Binding of Jun and Plat 1 0.06 0.16 0.05
88 INT311729 Plat Positive_regulation of Positive_regulation of Mmp9 1 0.34 0.71 0.04
89 INT265735 VEGFA Positive_regulation of Binding of KLKB1 1 0.04 0.36 0.04
90 INT311730 Binding of Plat and Lrp1 1 0.14 0.65 0.04
91 INT259927 Positive_regulation of Plat Positive_regulation of Jun 1 0.08 0.78 0.04
92 INT265745 FLT1 Positive_regulation of Binding of KLKB1 1 0.04 0.36 0.04
93 INT311726 Plat Positive_regulation of Gene_expression of Sele 1 0.09 0.6 0.04
94 INT294210 Binding of Ldlr and Plat 1 0.42 0.06 0.04
95 INT348757 Plat Negative_regulation of Cldn5 1 0.16 0.3 0.03
96 INT311724 Plat Positive_regulation of Gene_expression of Selp 1 0.11 0.6 0.03
97 INT311736 Plat Positive_regulation of Gene_expression of Icam2 1 0.35 0.6 0.03
98 INT311732 Plat Positive_regulation of Gene_expression of Esam 1 0.07 0.59 0.03
99 INT259925 Regulation of Plat Positive_regulation of Jun 1 0.05 0.11 0.03
100 INT344708 Hdl1 Positive_regulation of Gene_expression of Plat 1 0.08 1.26 0
101 INT265760 Binding of KLKB1 and VEGFA 1 0.04 0.14 0
102 INT294202 Binding of Plat and Plg 1 0.11 0 0
103 INT344266 Binding of APOH and CD40LG 1 0.04 0.31 0
104 INT265754 Binding of FLT1 and KLKB1 1 0.03 0.07 0
105 INT337630 Binding of PLAT and PLG 1 0.07 0.69 0
106 INT265747 Binding of KLKB1 and KL 1 0.02 0 0
107 INT57794 Binding of PLAT and Plg 1 0.00 0.15 0
108 INT294205 Serpine1 Negative_regulation of Plat 1 0.47 0.51 0
109 INT348759 Plat Regulation of LDHA 1 0.04 0.23 0
110 INT136516 PLAT Regulation of MLF1 1 0.02 0 0
111 INT294204 Binding of Serpine1 and Plat 1 0.46 0.2 0
112 INT57792 Binding of Plg and Plat 1 0.00 0.07 0
113 INT232911 Binding of KRT18 and PLAT 1 0.05 1.3 0
114 INT308053 PLAT Positive_regulation of KRT20 1 0.00 0.24 0
115 INT265728 Positive_regulation of Binding of KLKB1 and VEGFA 1 0.04 0 0
116 INT232915 Binding of KRT8 and PLAT 1 0.04 1.3 0
117 INT235495 PLAT Positive_regulation of Gene_expression of IL2 1 0.05 0 0
118 INT348758 Plat Positive_regulation of LDHA 1 0.04 0.42 0
119 INT57791 Binding of Serpine1 and Plat 1 0.00 0.07 0
120 INT232908 Binding of KRT19 and PLAT 1 0.05 1.31 0
121 INT265738 NRP1 Positive_regulation of KLKB1 1 0.03 0 0
122 INT196349 PLAT Positive_regulation of Gene_expression of PTGER2 1 0.00 1.1 0
123 INT337629 Binding of PLAT and CLEC3B 1 0.23 0.35 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for plasminogen activation. They are ordered first by their pain relevance and then by number of times they were reported in plasminogen activation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT82929 Gene_expression of Plat 58 0.78 26.96 13.85
2 INT24684 Localization of PLAT 30 0.78 26.21 13.56
3 INT27937 Gene_expression of Klkb1 35 0.55 1.86 10.08
4 INT15449 Positive_regulation of Plat 32 0.69 12.76 9.71
5 INT65390 Positive_regulation of Plat 30 0.70 23.31 9.31
6 INT13432 Positive_regulation of Klkb1 23 0.57 5.36 8.65
7 INT1925 Gene_expression of PLAT 47 0.75 34.76 7.88
8 INT10513 Gene_expression of Plat 44 0.76 19.49 7.17
9 INT124488 Positive_regulation of Gene_expression of Plat 14 0.70 5.46 6.52
10 INT1926 Positive_regulation of PLAT 54 0.66 31.42 6.49
11 INT17262 Negative_regulation of Plat 17 0.59 15.14 6.36
12 INT124825 Transcription of Plat 8 0.70 3.15 5.68
13 INT107247 Regulation of Plat 10 0.44 7.21 5.14
14 INT51839 Positive_regulation of Localization of PLAT 5 0.49 7.09 4.92
15 INT104668 Negative_regulation of Plat 27 0.49 17.18 4.83
16 INT1924 Regulation of PLAT 11 0.60 6.3 3.16
17 INT10517 Localization of Plat 16 0.47 8.44 3.11
18 INT10136 Negative_regulation of PLAT 23 0.42 11.18 3.02
19 INT46201 Gene_expression of KLKB1 21 0.53 3.01 2.87
20 INT124489 Regulation of Gene_expression of Plat 5 0.45 0.48 2.87
21 INT10101 Binding of PLAT 24 0.36 12.62 2.78
22 INT73029 Negative_regulation of Klkb1 7 0.35 0 2.72
23 INT10512 Positive_regulation of Gene_expression of Plat 8 0.46 1.4 2.69
24 INT9374 Regulation of Plat 19 0.61 6.04 2.55
25 INT124826 Positive_regulation of Transcription of Plat 3 0.68 0.33 2.38
26 INT10514 Negative_regulation of Gene_expression of Plat 8 0.47 6.22 2.24
27 INT6750 Positive_regulation of Klkb1 6 0.28 2.01 2.09
28 INT28830 Localization of Klkb1 9 0.61 0.6 1.96
29 INT27936 Positive_regulation of Gene_expression of Klkb1 5 0.41 1.28 1.75
30 INT8911 Regulation of DHCR24 1 0.05 1.91 1.71
31 INT25445 Binding of Plat 7 0.41 12.75 1.63
32 INT153156 Negative_regulation of KLKB1 5 0.48 7.88 1.6
33 INT23251 Positive_regulation of KLKB1 10 0.67 2.98 1.59
34 INT124824 Negative_regulation of Transcription of Plat 1 0.43 0.48 1.54
35 INT153515 Localization of Plat 10 0.77 4.21 1.4
36 INT2355 Negative_regulation of Klkb1 6 0.26 2.5 1.3
37 INT153514 Positive_regulation of Localization of Plat 2 0.62 0.55 1.23
38 INT116206 Transcription of Plat 3 0.67 1.52 1.18
39 INT59029 Positive_regulation of DHCR24 2 0.22 0.51 1.18
40 INT199315 Binding of Plat 8 0.34 7.02 1.14
41 INT4609 Gene_expression of Klkb1 5 0.47 0.81 1.03
42 INT116207 Positive_regulation of Transcription of Plat 1 0.49 0.66 1.02
43 INT171636 Negative_regulation of Gene_expression of PLAT 6 0.35 2.92 0.93
44 INT207500 Binding of Klkb1 2 0.31 0 0.87
45 INT4762 Negative_regulation of DHCR24 5 0.45 0.68 0.8
46 INT354257 Regulation of Localization of PLAT 1 0.18 0.91 0.79
47 INT134754 Positive_regulation of Gene_expression of PLAT 9 0.49 4.75 0.72
48 INT28835 Positive_regulation of Localization of Klkb1 2 0.41 0.17 0.69
49 INT46202 Positive_regulation of Gene_expression of KLKB1 2 0.04 0 0.68
50 INT83194 Binding of APOH 4 0.17 3.92 0.66
51 INT265802 Regulation of KLKB1 9 0.04 1.01 0.64
52 INT124487 Negative_regulation of Gene_expression of Plat 4 0.43 1.88 0.55
53 INT96610 Positive_regulation of F11 1 0.13 0.58 0.51
54 INT3561 Regulation of Klkb1 3 0.29 0.28 0.5
55 INT207492 Negative_regulation of Gene_expression of Klkb1 1 0.35 0 0.49
56 INT11363 Regulation of Gene_expression of PLAT 1 0.27 0.87 0.46
57 INT17835 Regulation of Localization of Plat 3 0.29 0.53 0.44
58 INT12343 Protein_catabolism of PLAT 2 0.76 0.73 0.44
59 INT258821 Negative_regulation of Localization of PLAT 4 0.57 3.32 0.43
60 INT34939 Positive_regulation of Negative_regulation of Plat 2 0.45 1 0.43
61 INT36793 Binding of KLKB1 3 0.40 0.51 0.42
62 INT96611 Binding of F11 1 0.13 0.51 0.42
63 INT133379 Negative_regulation of APOH 1 0.07 0.09 0.42
64 INT10102 Regulation of Binding of PLAT 2 0.42 1.24 0.41
65 INT25010 Positive_regulation of Localization of Plat 2 0.31 0.81 0.37
66 INT81221 Positive_regulation of APOH 1 0.02 1.24 0.36
67 INT17834 Negative_regulation of Localization of Plat 3 0.26 3.37 0.34
68 INT85646 Transcription of PLAT 2 0.67 1.2 0.34
69 INT14181 Binding of DHCR24 1 0.04 0 0.34
70 INT130344 Gene_expression of APOH 3 0.34 2.87 0.32
71 INT207495 Regulation of Gene_expression of Klkb1 1 0.22 0 0.32
72 INT83195 Regulation of Binding of APOH 1 0.13 0.88 0.31
73 INT207498 Regulation of Positive_regulation of Klkb1 1 0.42 0 0.29
74 INT227751 Negative_regulation of Positive_regulation of Plat 1 0.19 0.63 0.28
75 INT36795 Localization of KLKB1 3 0.78 1.05 0.27
76 INT207499 Transcription of Klkb1 2 0.57 0.86 0.27
77 INT2751 Regulation of Klkb1 2 0.11 0.25 0.25
78 INT273052 Negative_regulation of Binding of Plat 1 0.03 1.48 0.24
79 INT259916 Positive_regulation of Positive_regulation of Plat 4 0.48 1.32 0.22
80 INT1920 Positive_regulation of Positive_regulation of PLAT 3 0.40 2.29 0.22
81 INT96612 Regulation of Binding of F11 1 0.16 0.28 0.21
82 INT15255 Negative_regulation of Positive_regulation of PLAT 3 0.46 0.87 0.2
83 INT135460 Gene_expression of DHCR24 2 0.58 0.57 0.2
84 INT135459 Positive_regulation of Negative_regulation of DHCR24 1 0.38 0.18 0.19
85 INT135461 Protein_catabolism of DHCR24 1 0.44 0.27 0.17
86 INT186856 Positive_regulation of Binding of PLAT 1 0.13 0.69 0.15
87 INT171640 Negative_regulation of Transcription of PLAT 1 0.40 0.2 0.11
88 INT171619 Negative_regulation of Transcription of Plat 1 0.41 0.2 0.11
89 INT311720 Protein_catabolism of Plat 1 0.98 0.62 0.11
90 INT311715 Negative_regulation of Regulation of Plat 1 0.42 0.62 0.11
91 INT2743 Transcription of Klkb1 1 0.14 0.36 0.09
92 INT282750 Positive_regulation of Positive_regulation of Klkb1 1 0.02 0 0.09
93 INT2744 Regulation of Transcription of Klkb1 1 0.09 0.36 0.09
94 INT119002 Regulation of APOH 1 0.01 0.43 0.09
95 INT255790 Protein_catabolism of Plat 2 0.32 0.68 0.08
96 INT348753 Phosphorylation of Plat 1 0.66 0.43 0.05
97 INT270726 Negative_regulation of Binding of PLAT 1 0.05 1.03 0.04
98 INT60109 Positive_regulation of Positive_regulation of Plat 1 0.02 1.91 0.04
99 INT265776 Regulation of Binding of KLKB1 1 0.04 0.36 0.04
100 INT212956 Negative_regulation of Localization of Plat 1 0.11 1.23 0.03
101 INT311713 Regulation of Gene_expression of Plat 1 0.39 0.48 0.03
102 INT265791 Protein_catabolism of KLKB1 1 0.07 0 0
103 INT193182 Localization of DHCR24 1 0.10 0.22 0
104 INT109706 Negative_regulation of Negative_regulation of Plat 1 0.02 0.24 0
105 INT57789 Regulation of Positive_regulation of PLAT 1 0.01 0.07 0
106 INT265786 Positive_regulation of Positive_regulation of KLKB1 1 0.04 0.24 0
107 INT265789 Negative_regulation of Protein_catabolism of KLKB1 1 0.03 0 0
108 INT165983 Regulation of Gene_expression of Klkb1 1 0.29 0 0
109 INT265782 Regulation of Gene_expression of KLKB1 1 0.04 0 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox