GO:0032403

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Name protein complex binding
Categary Function
Go Slim No
Go Link GO:0032403
Unique Molecular Interactions 2615
Total Molecular Interactions 3693
Total Single Events 32376
Pain Genes Associated 244

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein complex binding. They are ordered first by their pain relevance and then by number of times they were reported for protein complex binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
2 INT166591 Binding of CALCA and DCLK3 4 0.30 0.69 12.18
3 INT180785 Gdnf Positive_regulation of Calca 1 0.23 1.96 8.04
4 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
5 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
6 INT296275 Binding of Dlg4 and Kcnip3 1 0.39 3.58 5.6
7 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
8 INT102122 Binding of Calca and RT1-M4 7 0.29 5.83 4.94
9 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8
10 INT24742 Binding of Calca and Vip 1 0.37 0.18 4.68
11 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
12 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
13 INT128998 Cxcl1 Positive_regulation of Localization of Calca 1 0.66 2.96 4.15
14 INT13969 Binding of Calca and Sst 3 0.32 0.6 4.02
15 INT200322 Binding of Rest and Sp3 1 0.39 2.93 3.98
16 INT13966 Calca Positive_regulation of Localization of Sst 5 0.49 0.75 3.91
17 INT130625 Prkcg Regulation of Prkaca 1 0.23 1.32 3.87
18 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
19 INT87491 CALCA Positive_regulation of Gene_expression of IL8 1 0.72 0.92 3.52
20 INT24710 Binding of Calca and SUB1P1 1 0.01 2.09 3.48
21 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
22 INT128292 Nts Positive_regulation of Insr 1 0.03 0.99 3.34
23 INT128291 Vom1r68 Positive_regulation of Insr 1 0.00 0.99 3.33
24 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
25 INT108471 Binding of CALCA and PNOC 1 0.29 0.64 3.25
26 INT7190 Syt17 Positive_regulation of Ctsb 1 0.16 0 3.23
27 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
28 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 0.51 1.79 3.22
29 INT7193 Abl2 Positive_regulation of Ctsb 1 0.21 0 3.21
30 INT270949 Binding of Slc6a3 and Cpe 1 0.28 0.25 3.19
31 INT29657 Binding of Calca and Calcb 1 0.26 0 3.16
32 INT85042 Binding of CCT6A and MAX 1 0.00 0 3.13
33 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01
34 INT106837 Binding of Oprm1 and Arrb2 3 0.32 0.83 3.01
35 INT37162 Binding of Calca and Cckar 1 0.04 0.55 3.01
36 INT100835 Binding of Calca and Akap12 1 0.07 0.41 2.92
37 INT166592 Binding of CALCA and RAMP1 2 0.35 0.33 2.91
38 INT73821 CALCA Positive_regulation of Localization of IL8 1 0.25 2.37 2.91
39 INT156381 Binding of Grin1 and Dlg4 1 0.39 0.86 2.9
40 INT298456 Prkaca Positive_regulation of Phosphorylation of Adarb1 1 0.00 1.86 2.85
41 INT194409 Binding of CALCA and IGKV1D-8 1 0.15 0 2.84
42 INT229497 Binding of Vim and Ndel1 1 0.33 3.5 2.81
43 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79
44 INT169134 Binding of Calca and Trpa1 1 0.37 3.37 2.79
45 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
46 INT326585 Binding of GYPA and SLC6A3 1 0.13 0.86 2.64
47 INT53648 Acot1 Positive_regulation of Localization of Calca 2 0.23 0 2.61
48 INT121698 HRAS Negative_regulation of Gene_expression of MMP3 1 0.06 0.5 2.6
49 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
50 INT57624 Calca Regulation of Positive_regulation of Trh 1 0.50 0 2.53
51 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
52 INT48526 Binding of Calca and Penk 1 0.24 1.03 2.51
53 INT136129 Calca Positive_regulation of ATP8A2 1 0.38 0.89 2.4
54 INT121746 Prkaca Positive_regulation of Ephb1 2 0.23 0.92 2.35
55 INT13967 Calca Positive_regulation of Sst 1 0.45 0 2.3
56 INT131257 ITIH4 Positive_regulation of Gene_expression of Nfkbia 1 0.23 1.41 2.3
57 INT152900 TRPV1 Regulation of Gene_expression of CALCA 1 0.69 0.73 2.29
58 INT152901 TRPV1 Regulation of Localization of CALCA 1 0.44 0.73 2.29
59 INT7195 Negative_regulation of Syt17 Positive_regulation of Ctsb 1 0.10 0 2.25
60 INT69887 Ngf Regulation of Calca 2 0.49 0.1 2.19
61 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15
62 INT135035 Binding of Hk1 and Tac1 1 0.35 0.18 2.14
63 INT251145 Binding of Grin2a and Dlg2 1 0.31 2.3 2.11
64 INT133946 Binding of DNM2 and OPRK1 1 0.11 0 2.1
65 INT79470 Mgat4a Regulation of Localization of Calca 1 0.08 1.72 2.1
66 INT85041 Binding of IGHG3 and MAX 1 0.00 0 2.09
67 INT89733 Binding of Calca and Nrm 1 0.31 0.71 2.09
68 INT281084 Prkaca Positive_regulation of Mapk1 2 0.25 0 2.06
69 INT63873 SRPX Positive_regulation of Localization of Calca 1 0.02 0.49 2.04
70 INT115042 Gdnf Regulation of Calca 1 0.53 0.25 2.03
71 INT26221 Calca Regulation of Gt(pU21)50Imeg 1 0.01 0 2.02
72 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
73 INT274372 Phc1 Negative_regulation of Slc6a3 1 0.06 0.47 1.99
74 INT213968 Binding of Calca and Mthfd1 1 0.05 0.16 1.99
75 INT146099 Binding of Oprm1 and Rgs9 1 0.48 0 1.95
76 INT104855 Prkaca Regulation of TRPV1 3 0.06 1.52 1.92
77 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92
78 INT112514 Binding of Prkaca and Trib3 1 0.03 1.18 1.9
79 INT186432 Prkaca Regulation of Creb1 1 0.14 0.45 1.9
80 INT24942 Calca Regulation of TAC1 1 0.13 0.7 1.89
81 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
82 INT13940 DNM2 Regulation of Localization of CGA 1 0.11 0 1.86
83 INT243043 Binding of Mmp9 and Timp1 1 0.05 0.25 1.86
84 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85
85 INT112517 Binding of Ephb1 and Prkaca 3 0.18 0.58 1.85
86 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84
87 INT163514 Ngf Positive_regulation of Gene_expression of Calca 1 0.30 2.21 1.82
88 INT155460 Tnfrsf1a Positive_regulation of Positive_regulation of Nfkb1 1 0.42 2.39 1.82
89 INT272616 Positive_regulation of Binding of Grin1 and Grin2a 2 0.30 1.36 1.8
90 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
91 INT203149 Binding of Mif and Osm 1 0.02 2.93 1.78
92 INT336556 SLC6A3 Positive_regulation of Gene_expression of GOPC 1 0.08 1.87 1.76
93 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75
94 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75
95 INT24934 Calca Regulation of Nka1 3 0.05 0.43 1.73
96 INT148090 Binding of CALCA and NCOR2 1 0.00 0.65 1.71
97 INT296280 Binding of Car2 and Dlg4 1 0.19 0.45 1.71
98 INT200335 Binding of Oprm1 and Rest 1 0.40 0.07 1.7
99 INT94617 KNG1 Positive_regulation of Localization of Calca 1 0.00 0.75 1.7
100 INT56134 CALCA Positive_regulation of POMC 2 0.71 0.72 1.68
101 INT102447 Binding of CALCA and CALCRL 2 0.26 0.33 1.67
102 INT139433 Binding of Prkaca and Prkca 1 0.37 0.13 1.67
103 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
104 INT94618 KNG1 Positive_regulation of Calca 1 0.00 0.75 1.66
105 INT144213 Nppa Positive_regulation of Localization of Calca 1 0.71 2.8 1.65
106 INT23889 Calca Positive_regulation of Localization of Tacr1 1 0.11 0.45 1.65
107 INT24157 Binding of CALCA and SFTPA1 2 0.07 0.96 1.64
108 INT122286 Prkaca Negative_regulation of Negative_regulation of Calca 1 0.12 0.54 1.63
109 INT155459 Tnfrsf1a Positive_regulation of Nfkb1 1 0.42 2.45 1.63
110 INT168612 Negative_regulation of Nos1 Negative_regulation of Positive_regulation of Mmp9 1 0.23 0.45 1.62
111 INT172206 Binding of Slc6a3 and ADHD1 2 0.03 2.76 1.61
112 INT168607 Negative_regulation of Nos1 Negative_regulation of Mmp9 1 0.23 0.45 1.61
113 INT160578 Binding of CALCA and TAC1 1 0.07 0.91 1.61
114 INT195930 OPRM1 Regulation of Prkaca 1 0.01 0 1.59
115 INT168609 Binding of Itgb1 and Mmp9 1 0.02 0.41 1.58
116 INT168611 Binding of Mmp9 and Ndor1 1 0.29 0.41 1.57
117 INT212660 Nr3c1 Regulation of KCNA1 1 0.00 1.25 1.57
118 INT168608 Binding of Grin2b and Mmp9 1 0.22 0.41 1.57
119 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
120 INT148935 Ramp1 Regulation of Calca 1 0.27 0.69 1.56
121 INT13968 Calca Negative_regulation of Positive_regulation of Sst 1 0.34 0 1.55
122 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
123 INT13970 Positive_regulation of Calca Positive_regulation of Sst 1 0.37 0 1.53
124 INT13965 Calca Positive_regulation of Positive_regulation of Sst 1 0.37 0 1.53
125 INT256360 Car2 Positive_regulation of Localization of Rela 1 0.14 0 1.51
126 INT166360 Negative_regulation of Crhr1 Negative_regulation of Positive_regulation of Pomc 1 0.02 0.36 1.5
127 INT93782 Racgap1 Positive_regulation of Rgs9 1 0.55 0.07 1.49
128 INT121741 Prkaca Negative_regulation of Positive_regulation of Creb1 1 0.10 0.2 1.49
129 INT125845 Positive_regulation of Pag1 Positive_regulation of Gene_expression of Arrb2 1 0.09 0.46 1.48
130 INT96784 Binding of CALCA and Calca 3 0.23 0.27 1.47
131 INT180791 Negative_regulation of Gdnf Regulation of Calca 1 0.17 0 1.47
132 INT180767 Bdnf Positive_regulation of Gene_expression of Calca 1 0.17 0 1.45
133 INT276681 Calca Regulation of Nav1 1 0.07 0.74 1.45
134 INT276686 Calca Regulation of Nav1 1 0.26 0.74 1.45
135 INT84434 Calca Negative_regulation of Negative_regulation of Hrh1 1 0.06 0.19 1.44
136 INT95325 HTR1B Negative_regulation of Calca 1 0.47 0.69 1.43
137 INT134760 Ghrl Regulation of Transcription of Calca 1 0.24 2.71 1.42
138 INT100908 Slc6a3 Regulation of Positive_regulation of Etf1 1 0.05 0 1.41
139 INT189299 Atp6v1e1 Positive_regulation of Htr2a 1 0.01 1.01 1.41
140 INT78974 Binding of Prkcg and Prkaca 2 0.31 0.35 1.4
141 INT144122 Binding of Calca and P2rx6 1 0.10 0 1.4
142 INT169163 Binding of Calca and Ctbs 1 0.00 0.51 1.4
143 INT299311 Binding of RPTOR and RICTOR 1 0.38 0.21 1.4
144 INT138099 Binding of Grin2a and Insrr 1 0.01 0.36 1.39
145 INT51213 Vip Regulation of Localization of Calca 1 0.38 0 1.39
146 INT8719 Npy Negative_regulation of Localization of Calca 1 0.06 0.26 1.39
147 INT262568 Prkaca Regulation of Trpv1 2 0.10 0.65 1.38
148 INT133933 Binding of DNM2 and TP53INP2 1 0.00 0 1.38
149 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38
150 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37
151 INT279165 Calca Regulation of Gene_expression of Fdft1 1 0.02 0.41 1.37
152 INT180810 Gopc Positive_regulation of Calca 1 0.02 0.28 1.36
153 INT290542 Crh Positive_regulation of Insr 1 0.02 0.36 1.36
154 INT229496 Binding of Ndel1 and Gopc 1 0.08 2.05 1.36
155 INT168722 Creb1 Positive_regulation of Calca 1 0.73 1.05 1.35
156 INT158079 Binding of Esr1 and Gper 1 0.31 0.97 1.35
157 INT222182 Binding of ESR1 and HLA-DRB2 1 0.00 3.1 1.35
158 INT151771 Binding of P2RX3 and Calca 1 0.04 0.89 1.34
159 INT298455 Calca Positive_regulation of Gene_expression of Ceacam3 1 0.17 0.47 1.34
160 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33
161 INT106839 Arrb2 Regulation of Oprm1 2 0.21 0.44 1.33
162 INT356317 Crhr1 Regulation of Gene_expression of Cea 1 0.18 0.65 1.33
163 INT180786 Calca Regulation of Positive_regulation of Ngf 1 0.40 0 1.32
164 INT356326 Crhr1 Regulation of Gene_expression of Helt 1 0.01 0.65 1.32
165 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
166 INT180764 Calca Regulation of Positive_regulation of Gdnf 1 0.21 0 1.32
167 INT180807 Calca Regulation of Sorbs1 1 0.02 0 1.32
168 INT180771 Calca Regulation of Positive_regulation of Bdnf 1 0.18 0 1.32
169 INT150890 Binding of Esr1 and Esr2 2 0.52 2.06 1.31
170 INT131256 Positive_regulation of Nfkb1 Positive_regulation of Gene_expression of Nfkbia 1 0.38 0.94 1.31
171 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3
172 INT299281 Binding of RPTOR and MAPKAP1 1 0.23 0.21 1.3
173 INT124926 Negative_regulation of Prkaca Negative_regulation of Localization of Pag1 1 0.00 0.61 1.3
174 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
175 INT121096 Binding of Calca and Trpv1 3 0.37 1.23 1.29
176 INT148775 Binding of Calca and Usf1 1 0.43 0.85 1.29
177 INT194408 Regulation of Binding of CALCA and DCLK3 1 0.15 0 1.29
178 INT138210 Mzb1 Regulation of Calca 1 0.25 0.41 1.29
179 INT22501 Binding of Calca and Pth 1 0.21 0.07 1.28
180 INT195929 Binding of OPRM1 and Prkaca 1 0.02 0.33 1.27
181 INT64077 Trpv1 Positive_regulation of Kcnma1 1 0.00 0.37 1.27
182 INT119713 Negative_regulation of Slc6a3 Positive_regulation of Cpu3 1 0.39 0.71 1.26
183 INT121464 Negative_regulation of Oprm1 Positive_regulation of Dnm2 1 0.34 0 1.26
184 INT124108 Binding of RYBP and Ccne1 1 0.09 0.34 1.26
185 INT116628 St13 Regulation of Positive_regulation of P9Ehs1 1 0.00 0 1.25
186 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25
187 INT202042 CAMK2N2 Negative_regulation of MMP9 1 0.01 0.73 1.25
188 INT251142 Binding of Dlg4 and Grin2a 3 0.30 0.5 1.24
189 INT88635 Ptger3 Positive_regulation of Localization of Calca 2 0.05 0 1.24
190 INT121465 Binding of Dnm2 and Oprm1 1 0.23 0 1.24
191 INT202036 CAMK2N2 Negative_regulation of MMP3 1 0.00 0.73 1.24
192 INT167278 Binding of OPRM1 and REST 1 0.08 0.94 1.24
193 INT141244 Fos Regulation of Prkaca 1 0.18 0.07 1.24
194 INT92800 Arrb2 Negative_regulation of Oprm1 1 0.37 0.33 1.24
195 INT195926 Prkaca Positive_regulation of Trpv1 1 0.10 0.44 1.24
196 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23
197 INT184919 Binding of da and Slc6a3 1 0.12 0.33 1.23
198 INT103031 Calca Positive_regulation of Ptgs1 2 0.46 0.98 1.22
199 INT334129 Acsm3 Positive_regulation of Gene_expression of Icam1 1 0.22 2.89 1.22
200 INT52955 Binding of Slc6a3 and Pdpn 1 0.17 1.11 1.22

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein complex binding. They are ordered first by their pain relevance and then by number of times they were reported in protein complex binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 2008 0.81 518.3 1408.65
2 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84
3 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08
4 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04
5 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38
6 INT2649 Regulation of Calca 433 0.62 146.05 330.95
7 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45
8 INT626 Localization of CALCA 289 0.81 125.39 221.15
9 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57
10 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2
11 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47
12 INT2541 Binding of Calca 200 0.48 67.14 134.62
13 INT5008 Localization of Calca 204 0.81 80.35 125.16
14 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75
15 INT52651 Positive_regulation of Prkaca 136 0.67 40.82 99.16
16 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61
17 INT15898 Positive_regulation of Prkaca 199 0.70 50.89 87.54
18 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24
19 INT5780 Regulation of Gene_expression of Calca 90 0.62 59.52 85.03
20 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71
21 INT49111 Negative_regulation of Prkaca 102 0.59 27.44 71.77
22 INT53964 Negative_regulation of Prkaca 131 0.58 38.76 69.52
23 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34
24 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64
25 INT6761 Binding of CALCA 100 0.48 26.71 62.05
26 INT4760 Negative_regulation of Gene_expression of Calca 93 0.59 34.19 60.3
27 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81
28 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01
29 INT4241 Regulation of CALCA 87 0.62 28.19 55.29
30 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5
31 INT4891 Transcription of Calca 81 0.72 35.27 53.75
32 INT8700 Positive_regulation of Positive_regulation of Calca 56 0.67 21.69 53.66
33 INT62543 Gene_expression of Icam1 231 0.78 187.58 52.71
34 INT97674 Positive_regulation of Localization of Calca 70 0.69 27.71 51.79
35 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34
36 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59
37 INT51627 Gene_expression of Grin2a 82 0.76 25.09 47.6
38 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81
39 INT66383 Phosphorylation of Prkaca 143 0.80 30.85 43.38
40 INT115384 Positive_regulation of Mmp9 121 0.68 94.74 43.02
41 INT11406 Positive_regulation of Localization of CALCA 49 0.70 20.64 42.8
42 INT29496 Gene_expression of MMP3 136 0.75 49.49 41.78
43 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17
44 INT68975 Gene_expression of Mmp9 111 0.78 79.57 38.55
45 INT92515 Gene_expression of Grin2a 84 0.76 26.68 38.37
46 INT81037 Negative_regulation of Slc6a3 70 0.59 15.31 37.01
47 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69
48 INT51017 Positive_regulation of Icam1 113 0.70 81.16 35.55
49 INT8784 Negative_regulation of Positive_regulation of Calca 40 0.59 14.67 33.49
50 INT8746 Negative_regulation of Calca 50 0.59 21.22 33.45
51 INT99610 Localization of MMP9 126 0.79 48.46 32.67
52 INT89055 Phosphorylation of Prkaca 60 0.61 13.41 32.49
53 INT8691 Localization of Insr 85 0.80 9.27 30.32
54 INT68973 Positive_regulation of Mmp9 89 0.52 58.56 30.04
55 INT72252 Gene_expression of Kcnma1 63 0.64 20.47 29.56
56 INT5300 Regulation of Insr 54 0.60 11.33 29.26
57 INT23463 Positive_regulation of Gene_expression of CALCA 47 0.70 18.14 28.76
58 INT116737 Localization of Mif 63 0.81 52.97 28.11
59 INT22499 Regulation of Calca 42 0.62 17.32 28.02
60 INT66381 Regulation of Prkaca 40 0.62 13.38 27.96
61 INT37296 Binding of Esr1 117 0.43 62.51 27.33
62 INT5923 Negative_regulation of Rtn4 50 0.36 24.19 27.2
63 INT93360 Gene_expression of Slc6a3 63 0.78 19.54 26.55
64 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42
65 INT20462 Binding of ESR1 210 0.44 102.7 26.34
66 INT86062 Positive_regulation of Tnfrsf1a 51 0.69 40.69 26.2
67 INT80791 Gene_expression of Slc6a3 113 0.78 11.89 25.76
68 INT140193 Gene_expression of Mmp3 58 0.71 49.65 25.4
69 INT93717 Gene_expression of Mmp3 85 0.78 33.95 24.89
70 INT96904 Regulation of Prkaca 33 0.44 10.86 24.51
71 INT64076 Positive_regulation of Kcnma1 47 0.40 11.52 24.19
72 INT15511 Gene_expression of Tnfrsf1a 84 0.76 63.3 24.03
73 INT93738 Gene_expression of Tnfrsf1a 63 0.74 57.66 23.09
74 INT12114 Positive_regulation of Tnfrsf1a 46 0.69 36.26 22.54
75 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52
76 INT48407 Positive_regulation of Gene_expression of Icam1 61 0.70 57.91 21.54
77 INT8358 Negative_regulation of Localization of CALCA 25 0.59 11.79 21.51
78 INT61825 Negative_regulation of Slc6a3 47 0.59 6.52 21.27
79 INT89805 Gene_expression of Prkaca 45 0.77 11.03 20.77
80 INT40750 Gene_expression of Mif 61 0.78 34.59 20.28
81 INT101188 Gene_expression of Rela 81 0.56 23.43 19.15
82 INT90612 Positive_regulation of Grin2a 33 0.65 15.11 18.84
83 INT56239 Positive_regulation of Rtn4 20 0.26 14.05 18.8
84 INT7000 Positive_regulation of Htr2a 42 0.67 9.48 18.7
85 INT5922 Gene_expression of Rtn4 27 0.48 12.7 17.86
86 INT132997 Localization of Mmp9 59 0.80 45.9 17.61
87 INT4067 Negative_regulation of Esr1 97 0.50 43.45 17.52
88 INT17237 Regulation of Esr1 74 0.43 49.09 17.25
89 INT95767 Negative_regulation of Mmp9 72 0.57 49.14 17.1
90 INT62564 Gene_expression of Syp 40 0.76 15.56 17
91 INT35998 Positive_regulation of Gene_expression of Calca 31 0.70 16.16 16.98
92 INT62546 Positive_regulation of Gene_expression of Icam1 60 0.70 59.52 16.9
93 INT65214 Binding of Slc6a3 54 0.48 4.77 16.79
94 INT6150 Positive_regulation of Negative_regulation of Calca 20 0.68 4.06 16.26
95 INT26314 Positive_regulation of MMP3 48 0.67 22.14 16.17
96 INT56447 Positive_regulation of Icam1 64 0.64 64.14 16.16
97 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7
98 INT9751 Localization of Crhr1 26 0.78 10.47 15.69
99 INT92354 Localization of ESR1 77 0.75 33.04 15.51
100 INT116736 Positive_regulation of Mif 40 0.70 31.93 15.37
101 INT54356 Regulation of Slc6a3 48 0.58 5.86 15.24
102 INT71634 Gene_expression of SLC6A3 45 0.78 13.48 15.23
103 INT81486 Localization of MMP3 31 0.81 12.94 15.21
104 INT73916 Gene_expression of Esr1 58 0.77 26.59 15.15
105 INT113606 Positive_regulation of Gene_expression of Mmp9 46 0.64 44 15.07
106 INT12891 Negative_regulation of MMP3 41 0.58 17.99 15.06
107 INT79227 Negative_regulation of Gene_expression of Icam1 45 0.59 41.65 14.97
108 INT93482 Localization of Rela 56 0.78 24.52 14.82
109 INT14647 Positive_regulation of Grin2a 26 0.67 4.69 14.8
110 INT5324 Binding of Htr2a 23 0.47 7.14 14.66
111 INT20420 Gene_expression of MYC 99 0.75 49.32 14.36
112 INT97100 Negative_regulation of Dlg4 16 0.58 6.18 14.36
113 INT77619 Gene_expression of Prkaca 43 0.75 8.55 14.13
114 INT53070 Regulation of Rtn4 15 0.22 9.35 13.77
115 INT14768 Negative_regulation of Positive_regulation of Insr 16 0.56 5.51 13.59
116 INT95427 Positive_regulation of Mmp3 39 0.70 15.28 13.36
117 INT2038 Localization of Esr1 104 0.79 40.12 13.27
118 INT59665 Positive_regulation of Ugt1a6 24 0.69 7.24 13.25
119 INT144646 Positive_regulation of Rela 53 0.67 27.78 13.2
120 INT89842 Phosphorylation of Src 34 0.69 9.57 13.08
121 INT65109 Negative_regulation of Transcription of Calca 16 0.59 8.63 12.84
122 INT88789 Gene_expression of Dlg4 26 0.78 4.41 12.74
123 INT103997 Phosphorylation of Grin2a 17 0.64 10.75 12.67
124 INT26217 Binding of Calca 22 0.48 5.22 12.57
125 INT28458 Localization of Slc6a3 31 0.76 2.33 12.49
126 INT49975 Binding of SLC6A3 34 0.47 9.86 12.41
127 INT11244 Transcription of CALCA 21 0.69 3.61 12.27
128 INT100799 Negative_regulation of Grin2a 27 0.57 7.33 12.2
129 INT79545 Positive_regulation of Gene_expression of ESR1 82 0.64 39.42 12.18
130 INT110988 Gene_expression of Insr 58 0.42 42.12 12.18
131 INT15136 Regulation of Positive_regulation of Calca 12 0.62 3.02 12.16
132 INT6151 Negative_regulation of Negative_regulation of Calca 14 0.58 4.86 11.81
133 INT94981 Gene_expression of Arrb2 12 0.70 2.11 11.75
134 INT93715 Negative_regulation of MMP9 69 0.55 36.05 11.73
135 INT72949 Binding of Mif 31 0.46 23.12 11.65
136 INT51625 Regulation of Gene_expression of Grin2a 12 0.60 3.28 11.6
137 INT78970 Positive_regulation of Positive_regulation of Prkaca 14 0.47 3.06 11.49
138 INT105754 Regulation of St13 8 0.28 0.75 11.41
139 INT47702 Gene_expression of Sptan1 24 0.76 7.6 11.36
140 INT68976 Positive_regulation of Gene_expression of Mmp9 34 0.42 28.21 11.28
141 INT27258 Regulation of Htr2a 18 0.60 6.37 11.06
142 INT91357 Regulation of Dnm2 5 0.61 0 11.06
143 INT104039 Positive_regulation of Crhr1 15 0.70 8.34 10.99
144 INT111264 Gene_expression of Rgs9 16 0.76 1.96 10.94
145 INT5779 Positive_regulation of Transcription of Calca 15 0.62 5.61 10.86
146 INT11669 Gene_expression of Htr2a 17 0.75 6.78 10.75
147 INT93967 Binding of Slc6a3 22 0.48 6.81 10.74
148 INT101203 Negative_regulation of Gene_expression of Calca 12 0.59 7.06 10.72
149 INT91774 Gene_expression of Nr3c1 27 0.78 16.14 10.7
150 INT71633 Negative_regulation of SLC6A3 25 0.59 10.5 10.69
151 INT51626 Transcription of Grin2a 16 0.68 1.65 10.5
152 INT81538 Phosphorylation of Nfkbia 27 0.62 8.86 10.49
153 INT90639 Positive_regulation of Slc6a3 25 0.61 10.95 10.41
154 INT7458 Negative_regulation of Kcnma1 30 0.43 6.61 10.4
155 INT89282 Regulation of MMP9 39 0.60 25.45 10.34
156 INT93036 Negative_regulation of Grin2a 23 0.50 7.1 10.32
157 INT64193 Regulation of Grin2a 19 0.54 2.98 10.31
158 INT106477 Positive_regulation of Syp 21 0.68 8.69 10.3
159 INT56450 Negative_regulation of Gene_expression of Icam1 33 0.52 27.21 10.15
160 INT113605 Negative_regulation of Gene_expression of Mmp9 25 0.41 22.92 9.98
161 INT62269 Gene_expression of Cdkn1a 60 0.73 35.78 9.84
162 INT35835 Positive_regulation of Htr2a 17 0.67 10.68 9.81
163 INT126031 Negative_regulation of Gene_expression of MMP9 40 0.57 22.71 9.79
164 INT66382 Positive_regulation of Phosphorylation of Prkaca 33 0.49 7.05 9.69
165 INT16580 Negative_regulation of Htr2a 18 0.57 3.8 9.63
166 INT102987 Regulation of MMP3 23 0.60 9.35 9.54
167 INT125247 Negative_regulation of Mmp9 42 0.43 23.68 9.37
168 INT47301 Gene_expression of Ctsl 27 0.76 7.72 9.32
169 INT129585 Gene_expression of St13 17 0.59 4.46 9.3
170 INT106595 Negative_regulation of Dnm2 10 0.58 0.15 9.29
171 INT78769 Regulation of Grin2a 16 0.58 5.22 9.28
172 INT40609 Binding of Prkaca 23 0.36 3.42 9.19
173 INT152668 Negative_regulation of EP300 13 0.38 7.78 9.03
174 INT89845 Positive_regulation of Src 19 0.44 7.5 9.01
175 INT187190 Positive_regulation of Localization of MMP9 27 0.68 8.1 8.93
176 INT7572 Regulation of Crhr1 8 0.45 5.6 8.93
177 INT111258 Regulation of Rgs9 11 0.54 1.81 8.9
178 INT103251 Negative_regulation of Localization of Calca 13 0.43 9.36 8.86
179 INT71478 Positive_regulation of Positive_regulation of Prkaca 21 0.37 5.14 8.85
180 INT26751 Regulation of Nr3c1 13 0.61 6.58 8.65
181 INT80872 Protein_catabolism of Nfkbia 28 0.92 10.56 8.62
182 INT108643 Gene_expression of Dlg4 61 0.76 8.63 8.58
183 INT168096 Transcription of Cav3 1 0.72 7.23 8.58
184 INT77790 Positive_regulation of Gene_expression of Tnfrsf1a 16 0.67 15.88 8.5
185 INT8761 Negative_regulation of Binding of Calca 12 0.43 3.59 8.32
186 INT146343 Regulation of Slc6a3 17 0.60 7.33 8.27
187 INT59276 Transcription of Htr2a 12 0.69 10.47 8.25
188 INT95297 Gene_expression of Nfkbia 14 0.68 7.61 8.24
189 INT28461 Positive_regulation of Localization of Slc6a3 8 0.41 0 8.24
190 INT142526 Positive_regulation of Gene_expression of Prkaca 12 0.46 2.48 8.05
191 INT15687 Regulation of ESR1 91 0.60 40.42 7.95
192 INT62944 Regulation of Icam1 33 0.47 23.52 7.94
193 INT113671 Negative_regulation of Mmp3 26 0.49 6.33 7.88
194 INT48404 Regulation of Gene_expression of Icam1 21 0.62 15.1 7.81
195 INT32210 Gene_expression of Mif 13 0.75 28.48 7.79
196 INT184845 Negative_regulation of Gene_expression of Slc6a3 13 0.59 3.25 7.79
197 INT28457 Positive_regulation of Slc6a3 26 0.50 3.64 7.76
198 INT103659 Gene_expression of Muc4 10 0.78 7.2 7.7
199 INT14207 Gene_expression of DNM2 20 0.67 5.76 7.64
200 INT7570 Transcription of Crhr1 7 0.66 6.6 7.6
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