GO:0032868

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Name response to insulin stimulus
Categary Process
Go Slim No
Go Link GO:0032868
Unique Molecular Interactions 2467
Total Molecular Interactions 3514
Total Single Events 32318
Pain Genes Associated 110

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to insulin stimulus. They are ordered first by their pain relevance and then by number of times they were reported for response to insulin stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
2 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
3 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
4 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
5 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
6 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
7 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
8 INT128292 Nts Positive_regulation of Insr 1 0.03 0.99 3.34
9 INT128291 Vom1r68 Positive_regulation of Insr 1 0.00 0.99 3.33
10 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
11 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
12 INT85042 Binding of CCT6A and MAX 1 0.00 0 3.13
13 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3
14 INT150889 Il1a Regulation of Il10 1 0.22 3.49 2.95
15 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
16 INT318996 Binding of CCR3 and CCL5 1 0.07 3.39 2.9
17 INT319003 Binding of CCR1 and CCL5 1 0.08 3.38 2.89
18 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
19 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
20 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78
21 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
22 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
23 INT278948 LEP Positive_regulation of Gene_expression of PTGER2 1 0.09 4.04 2.69
24 INT150457 Binding of Sort1 and Prss12 3 0.21 1.36 2.64
25 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
26 INT107812 Nppa Positive_regulation of Localization of Sst 1 0.48 0.54 2.51
27 INT149494 PNOC Negative_regulation of Gene_expression of CCL5 1 0.19 0.52 2.46
28 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36
29 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
30 INT18197 Ghrh Positive_regulation of Localization of Ggh 4 0.46 0 2.23
31 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
32 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
33 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
34 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
35 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
36 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
37 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
38 INT85041 Binding of IGHG3 and MAX 1 0.00 0 2.09
39 INT126400 ITIH4 Positive_regulation of Gene_expression of Il6 1 0.00 2.11 2.08
40 INT64750 Binding of Oprm1 and Pck1 2 0.41 0.51 2.07
41 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
42 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
43 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
44 INT83170 Lep Regulation of Cck 5 0.43 0.68 1.96
45 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
46 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
47 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
48 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
49 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
50 INT305741 Binding of Kcnk2 and Sort1 1 0.54 1.01 1.8
51 INT150456 Binding of Sort1 and Nts 3 0.45 0.64 1.79
52 INT23392 Gal Regulation of Trpv1 1 0.05 0.33 1.77
53 INT37840 Binding of Cyp27b1 and Oprd1 1 0.01 0 1.73
54 INT185143 Elane Positive_regulation of Pik3r1 1 0.01 0 1.72
55 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
56 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
57 INT144213 Nppa Positive_regulation of Localization of Calca 1 0.71 2.8 1.65
58 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
59 INT54601 Binding of Mtor and Ache 1 0.20 0.8 1.58
60 INT107815 Gene_expression of Sst Positive_regulation of Localization of Nppa 1 0.52 0.27 1.57
61 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
62 INT212660 Nr3c1 Regulation of KCNA1 1 0.00 1.25 1.57
63 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
64 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54
65 INT126718 Binding of Il6 and Il6r 3 0.09 2.33 1.49
66 INT64628 Binding of Oxt and Gal 2 0.29 0.29 1.49
67 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
68 INT14375 Gal Positive_regulation of Localization of Prl 1 0.77 0 1.48
69 INT112034 Gabrb3 Positive_regulation of Pik3r1 1 0.08 0.18 1.48
70 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47
71 INT165450 Gal Regulation of Ceacam3 1 0.41 0.06 1.47
72 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
73 INT107813 Sst Negative_regulation of Localization of Nppa 1 0.44 0.2 1.46
74 INT155371 VIP Positive_regulation of Localization of IL6 1 0.64 3.37 1.44
75 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
76 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4
77 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4
78 INT223156 Il6 Regulation of A2m 1 0.11 2.79 1.39
79 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36
80 INT15277 Binding of Tac1 and Gal 1 0.39 0.19 1.35
81 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35
82 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
83 INT31772 Ednra Positive_regulation of Nppa 1 0.05 0.13 1.33
84 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
85 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
86 INT63407 Binding of Oprl1 and Pck1 1 0.40 0 1.29
87 INT31771 Penk Positive_regulation of Nppa 1 0.22 0.13 1.28
88 INT31773 Pdyn Positive_regulation of Nppa 1 0.12 0.13 1.27
89 INT64749 Negative_regulation of Binding of Oprm1 and Pck1 1 0.47 0.21 1.27
90 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26
91 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
92 INT121190 KCNMA1 Positive_regulation of Gene_expression of IL6 1 0.03 0.54 1.24
93 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
94 INT172141 IL10 Negative_regulation of Gene_expression of HLA-DRA 2 0.14 0.89 1.23
95 INT121189 KCNMA1 Positive_regulation of IL6 1 0.04 0.54 1.23
96 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22
97 INT62596 Binding of Edn1 and Nppa 1 0.27 1.77 1.22
98 INT70036 LTA Regulation of Negative_regulation of IL10 1 0.03 1.42 1.21
99 INT70046 IL12A Regulation of IL10 1 0.07 1.42 1.21
100 INT70039 IL1B Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
101 INT70040 TNF Regulation of Negative_regulation of IL10 1 0.09 1.42 1.21
102 INT70033 IL6 Regulation of PRF1 1 0.03 1.42 1.21
103 INT70030 IL1B Regulation of IL10 1 0.07 1.42 1.21
104 INT70047 IL6 Regulation of Negative_regulation of PRF1 1 0.03 1.42 1.21
105 INT70041 LTA Regulation of IL10 1 0.03 1.42 1.21
106 INT70034 IL12A Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
107 INT70029 IL6 Regulation of Negative_regulation of IL10 1 0.05 1.42 1.21
108 INT62368 Gal Positive_regulation of Localization of LH 3 0.36 0 1.2
109 INT209926 IL1B Regulation of PPARA 1 0.21 2.45 1.2
110 INT133496 Binding of Oprm1 and Cckbr 1 0.15 0 1.19
111 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18
112 INT330379 Gene_expression of IL10 Negative_regulation of Positive_regulation of MAPK14 1 0.00 1.95 1.18
113 INT93435 Binding of Casp3 and Cckbr 1 0.06 0.15 1.18
114 INT131887 Nr3c1 Regulation of Gene_expression of Prkcg 1 0.01 0 1.17
115 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16
116 INT94490 Il6 Positive_regulation of Gene_expression of Avp 1 0.33 1.97 1.15
117 INT147447 ADCYAP1 Regulation of Localization of RELA 1 0.50 1.12 1.15
118 INT94508 Il6 Positive_regulation of Gene_expression of AVP 1 0.42 1.96 1.14
119 INT203103 ACAN Negative_regulation of Gene_expression of IL10 1 0.02 1.31 1.12
120 INT94496 Il6 Positive_regulation of Gene_expression of Crh 1 0.29 1.94 1.12
121 INT294710 CRP Positive_regulation of Gene_expression of IL6 1 0.63 1.9 1.12
122 INT202620 Binding of Ppara and Rxra 15 0.09 2.63 1.11
123 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11
124 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 0.01 2.25 1.11
125 INT223154 Negative_regulation of Mapk14 Negative_regulation of Localization of Il6 1 0.19 1.13 1.11
126 INT229913 Positive_regulation of Ntsr1 Positive_regulation of Gene_expression of Egr1 1 0.12 1.33 1.11
127 INT4752 Gal Negative_regulation of Localization of Calca 1 0.41 0.06 1.11
128 INT133497 Binding of Oprm1 and Cckbr 1 0.03 0 1.1
129 INT223157 Abat Negative_regulation of Localization of Il6 1 0.05 1.13 1.1
130 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1
131 INT81788 Binding of AGRP and MC4R 4 0.51 0 1.09
132 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
133 INT305734 Binding of Sort1 and Trpv1 1 0.01 0.5 1.08
134 INT62365 Gal Regulation of Localization of LH 1 0.33 0 1.07
135 INT5106 Gal Positive_regulation of Localization of Ghrh 1 0.21 0 1.07
136 INT85040 Positive_regulation of Binding of CCT6A and MAX 1 0.00 0 1.06
137 INT331108 Mc1r Positive_regulation of Mc4r 1 0.44 1.05 1.06
138 INT292531 Il10 Negative_regulation of Positive_regulation of Mapk14 1 0.15 1.13 1.06
139 INT57986 Il1b Regulation of Positive_regulation of Il6 2 0.39 0.23 1.05
140 INT120316 Ghrh Regulation of Il6 1 0.11 0.95 1.05
141 INT85039 Binding of GPM6A and MAX 1 0.00 0 1.05
142 INT120310 Ghrh Regulation of Positive_regulation of Il6 1 0.18 0.95 1.05
143 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03
144 INT33142 Pck1 Positive_regulation of Npr1 4 0.01 0.5 1.02
145 INT61617 PTGER2 Regulation of Gene_expression of IL6 3 0.11 1.13 1.02
146 INT87025 ZAK Positive_regulation of Gene_expression of IL6 2 0.11 1.59 1.02
147 INT229914 Egr1 Positive_regulation of Phosphorylation of Mapk3 1 0.46 1.03 1.02
148 INT218310 IL6 Positive_regulation of Localization of CRP 1 0.29 3.33 1.02
149 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01
150 INT117311 HP Positive_regulation of Lep 1 0.00 1.78 1.01
151 INT278962 LEP Positive_regulation of CPOX 1 0.05 1.33 1
152 INT278946 IL6 Regulation of Gene_expression of IL8 1 0.20 1.9 1
153 INT317564 Pik3r1 Regulation of Negative_regulation of Oprm1 1 0.13 0.07 1
154 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99
155 INT86181 SFTPA1 Positive_regulation of IL6 1 0.07 0.32 0.99
156 INT244133 DDB1 Positive_regulation of Gene_expression of IL6 1 0.01 1.91 0.99
157 INT209923 IL17A Negative_regulation of PPARA 1 0.14 2.46 0.99
158 INT69307 Prkcq Negative_regulation of TH1L 1 0.00 0.98 0.98
159 INT113743 Mc3r Regulation of Gene_expression of Agrp 1 0.05 0.9 0.98
160 INT5107 Gal Positive_regulation of Localization of Sstr1 1 0.09 0 0.98
161 INT292530 Il10 Negative_regulation of Localization of Il1a 1 0.06 1.09 0.97
162 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
163 INT25272 Binding of Ggh and Ghrh 1 0.22 0 0.97
164 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
165 INT11392 Cck Positive_regulation of Cckbr 1 0.52 0 0.96
166 INT61860 Akr1d1 Regulation of Egr1 1 0.01 0 0.96
167 INT278940 LEP Positive_regulation of Gene_expression of IL8 1 0.34 1.68 0.96
168 INT61861 Akr1d1 Regulation of Positive_regulation of Egr1 1 0.01 0 0.96
169 INT5108 Gal Positive_regulation of Ghrh 1 0.21 0 0.96
170 INT5104 Gal Positive_regulation of Sstr1 1 0.06 0 0.96
171 INT163390 Il6 Positive_regulation of Gene_expression of Crp 2 0.03 3.42 0.95
172 INT299988 IL6 Positive_regulation of Localization of IL8 1 0.05 0.81 0.94
173 INT33976 Trmt2a Negative_regulation of Binding of Fads1 1 0.00 0 0.94
174 INT285418 IRF6 Positive_regulation of Localization of IL6 3 0.05 0.66 0.93
175 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93
176 INT336017 Vip Regulation of Tlr4 1 0.22 1.23 0.93
177 INT114883 Akt1 Regulation of Pik3r1 2 0.16 0.65 0.92
178 INT134785 Il2rb Regulation of Gene_expression of IL6 1 0.00 1.16 0.92
179 INT134784 Il2rb Regulation of IL6 1 0.00 1.16 0.92
180 INT61859 Akr1d1 Positive_regulation of Egr1 1 0.01 0 0.92
181 INT61862 Slc3a1 Positive_regulation of Egr1 1 0.05 0 0.92
182 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
183 INT343909 IgG Positive_regulation of Gene_expression of TLR4 1 0.04 3.49 0.91
184 INT78062 Il1a Positive_regulation of Localization of Il6 3 0.24 0.48 0.9
185 INT137092 Ntf3 Negative_regulation of Gene_expression of Gal 1 0.47 1.01 0.9
186 INT64717 Pomc Positive_regulation of Il6 1 0.13 0.19 0.9
187 INT40636 Mif Negative_regulation of Pomc 1 0.25 0.07 0.9
188 INT141965 Binding of ADM and CALCRL 5 0.33 3.6 0.89
189 INT168281 Tlr4 Positive_regulation of Phosphorylation of Mapk4 1 0.06 1.05 0.89
190 INT159962 Rock2 Regulation of Localization of Il6 1 0.09 2.7 0.88
191 INT253992 Cxcl12 Positive_regulation of Mif 1 0.46 1.31 0.88
192 INT305742 Binding of Sort1 and Gtf3a 1 0.01 0.64 0.88
193 INT231716 Binding of IL6 and DIP 1 0.24 1.55 0.87
194 INT272039 Ddc Positive_regulation of Gene_expression of Aanat 1 0.00 0.26 0.87
195 INT37839 Positive_regulation of Binding of Cyp27b1 and Oprd1 1 0.01 0 0.86
196 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
197 INT199492 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.81 0.86
198 INT199487 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.86
199 INT199491 Il6 Positive_regulation of Positive_regulation of Il6 1 0.00 0.81 0.86
200 INT226337 Binding of IL10 and IL10RA 2 0.24 2.51 0.85

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to insulin stimulus. They are ordered first by their pain relevance and then by number of times they were reported in response to insulin stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
2 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
3 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
4 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
5 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52
6 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36
7 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
8 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84
9 INT12082 Localization of IL6 365 0.81 241.78 105.78
10 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14
11 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24
12 INT5617 Localization of Nppa 266 0.81 83.51 83.89
13 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45
14 INT8650 Gene_expression of Gal 152 0.78 61.97 81.72
15 INT5861 Gene_expression of Egr1 203 0.78 49.35 68.13
16 INT19511 Localization of Il6 212 0.81 118.17 67.67
17 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61
18 INT10706 Regulation of Il6 150 0.62 93.23 62.34
19 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87
20 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72
21 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09
22 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
23 INT12717 Binding of Pck1 85 0.47 12.49 54.81
24 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5
25 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42
26 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78
27 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15
28 INT5623 Positive_regulation of Nppa 174 0.70 69.96 52.33
29 INT122041 Binding of Ppara 308 0.48 189.17 51.48
30 INT9210 Regulation of IL6 166 0.62 125.61 49.95
31 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59
32 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31
33 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5
34 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67
35 INT5039 Positive_regulation of Gal 67 0.68 27.97 37.36
36 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53
37 INT5620 Positive_regulation of Localization of Nppa 105 0.70 30.23 36.45
38 INT48896 Positive_regulation of Gene_expression of Il10 73 0.70 43.14 35.5
39 INT103094 Binding of PPARA 308 0.47 177.26 34.75
40 INT5862 Positive_regulation of Egr1 82 0.70 30.4 33.96
41 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07
42 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
43 INT8691 Localization of Insr 85 0.80 9.27 30.32
44 INT6196 Regulation of Nppa 83 0.62 30.31 30.18
45 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52
46 INT86437 Binding of IL6 154 0.48 121.22 29.3
47 INT5300 Regulation of Insr 54 0.60 11.33 29.26
48 INT4868 Gene_expression of GAL 75 0.78 22.23 29.02
49 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55
50 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19
51 INT116737 Localization of Mif 63 0.81 52.97 28.11
52 INT115385 Negative_regulation of Ppara 154 0.58 129.05 27.58
53 INT5206 Gene_expression of AR 316 0.78 113.83 27.29
54 INT6054 Positive_regulation of Gene_expression of Egr1 67 0.70 18.45 25.93
55 INT8205 Negative_regulation of Nppa 77 0.59 26.43 25.72
56 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66
57 INT5622 Gene_expression of Nppa 101 0.78 49.46 25.31
58 INT101483 Gene_expression of Lep 159 0.78 104.77 25.12
59 INT57874 Gene_expression of Egr1 113 0.78 68.46 24.95
60 INT134651 Binding of TLR4 89 0.48 66.96 23.19
61 INT74423 Localization of IL10 91 0.80 61.6 22.95
62 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76
63 INT61116 Positive_regulation of Ppara 119 0.69 58.62 21.6
64 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41
65 INT5040 Regulation of Gal 42 0.60 12.72 21.18
66 INT112029 Positive_regulation of Pik3r1 90 0.67 38.76 20.95
67 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66
68 INT78901 Localization of CCL5 67 0.78 40.79 20.59
69 INT51474 Binding of Il6 55 0.48 44.99 20.52
70 INT40750 Gene_expression of Mif 61 0.78 34.59 20.28
71 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22
72 INT69304 Negative_regulation of Il10 47 0.59 36.88 19.79
73 INT74286 Regulation of Il10 42 0.44 28.06 19.44
74 INT64442 Regulation of Mc4r 6 0.62 5.22 19.09
75 INT51054 Negative_regulation of Localization of IL6 45 0.59 24.48 18.97
76 INT5099 Localization of Gal 46 0.81 10.66 18.93
77 INT89594 Gene_expression of Ccl5 44 0.54 24.08 18.62
78 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
79 INT61626 Transcription of IL6 73 0.72 42.04 17.86
80 INT72564 Localization of Il10 41 0.78 28.62 17.6
81 INT5618 Regulation of Localization of Nppa 36 0.62 13.42 17.46
82 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
83 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33
84 INT48892 Transcription of Il10 31 0.71 27.26 16.77
85 INT1000 Localization of Ggh 31 0.75 2.74 16.41
86 INT4866 Positive_regulation of GAL 32 0.67 13.02 16.16
87 INT50932 Positive_regulation of Positive_regulation of Il6 36 0.69 24.9 16.12
88 INT61117 Gene_expression of Ppara 158 0.68 69.3 15.98
89 INT112027 Gene_expression of Pik3r1 58 0.75 30.9 15.95
90 INT62681 Negative_regulation of LEP 93 0.59 66.97 15.77
91 INT116736 Positive_regulation of Mif 40 0.70 31.93 15.37
92 INT64447 Transcription of Mc4r 14 0.61 6.08 15.29
93 INT75908 Regulation of LEP 77 0.60 60.16 15.19
94 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99
95 INT103096 Regulation of PPARA 113 0.60 62.47 14.57
96 INT100139 Positive_regulation of Gene_expression of PPARA 160 0.63 97.78 14.53
97 INT14264 Binding of Gal 39 0.47 5.7 14.48
98 INT151120 Negative_regulation of Tlr4 18 0.59 21.09 14.46
99 INT57878 Positive_regulation of Gene_expression of Egr1 36 0.70 20.42 14.45
100 INT7587 Localization of GAL 27 0.78 4.79 14.29
101 INT8986 Positive_regulation of Gene_expression of Gal 24 0.67 10.96 14.09
102 INT55256 Negative_regulation of Localization of Il6 38 0.58 16.12 13.67
103 INT14768 Negative_regulation of Positive_regulation of Insr 16 0.56 5.51 13.59
104 INT64445 Gene_expression of Mc4r 17 0.78 5.06 12.91
105 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9
106 INT122037 Regulation of Ppara 93 0.62 56.28 12.89
107 INT114420 Negative_regulation of Pik3r1 67 0.54 34.86 12.82
108 INT14764 Negative_regulation of Localization of Nppa 28 0.59 11.29 12.82
109 INT55255 Positive_regulation of Localization of Il6 48 0.69 24.88 12.76
110 INT86950 Negative_regulation of Gene_expression of Il10 26 0.42 18.92 12.73
111 INT73641 Regulation of Lep 45 0.62 26.2 12.59
112 INT18539 Gene_expression of Pnmt 33 0.78 3.08 12.47
113 INT70050 Negative_regulation of IL10 56 0.58 37.45 12.39
114 INT12084 Regulation of Localization of IL6 36 0.61 20.32 12.34
115 INT194462 Localization of Ppara 94 0.78 68.33 12.09
116 INT11121 Positive_regulation of NPPA 64 0.70 34.09 11.96
117 INT61706 Regulation of Gene_expression of Gal 17 0.62 10.09 11.96
118 INT72949 Binding of Mif 31 0.46 23.12 11.65
119 INT50933 Transcription of Il6 38 0.72 24.31 11.58
120 INT5011 Negative_regulation of Gal 30 0.57 9.88 11.49
121 INT49396 Negative_regulation of Positive_regulation of Il6 29 0.59 16.39 11.31
122 INT126743 Positive_regulation of Gene_expression of LEP 61 0.66 50.02 11.17
123 INT118742 Positive_regulation of Tlr4 32 0.69 27.55 11.09
124 INT82079 Positive_regulation of Lep 79 0.70 40 11.07
125 INT15305 Positive_regulation of Mtor 51 0.67 8.28 11
126 INT7132 Localization of NPPA 53 0.81 19.79 10.86
127 INT85017 Positive_regulation of Mc4r 13 0.67 7.56 10.86
128 INT79656 Positive_regulation of NR3C1 14 0.68 6.38 10.83
129 INT89184 Gene_expression of Mc4r 55 0.77 23.85 10.65
130 INT4240 Positive_regulation of CCL5 32 0.58 20.55 10.65
131 INT144391 Gene_expression of RETN 42 0.75 40.48 10.47
132 INT173159 Localization of PPARA 96 0.74 64.55 10.26
133 INT20166 Negative_regulation of Mtor 32 0.56 10.64 10.25
134 INT85015 Gene_expression of ADM 29 0.73 30.75 10.21
135 INT78895 Regulation of CCL5 30 0.46 20.45 10.18
136 INT101481 Positive_regulation of Lep 81 0.69 62.59 9.95
137 INT49660 Positive_regulation of EGR1 54 0.69 32.17 9.89
138 INT81929 Negative_regulation of Gene_expression of IL10 41 0.57 27.99 9.87
139 INT122584 Negative_regulation of Gene_expression of PPARA 56 0.58 37.61 9.76
140 INT16356 Regulation of NPPA 33 0.62 13.24 9.53
141 INT87495 Positive_regulation of Gene_expression of CCL5 26 0.69 13.85 9.46
142 INT57876 Positive_regulation of Egr1 46 0.70 25.6 9.41
143 INT82078 Negative_regulation of Lep 54 0.59 20.47 9.38
144 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37
145 INT15307 Regulation of Mtor 27 0.48 4.7 9.34
146 INT73497 Regulation of IL10 33 0.45 22.6 9.19
147 INT73021 Gene_expression of EGR1 43 0.77 24.65 9.18
148 INT113734 Gene_expression of Agrp 31 0.77 11.04 9.02
149 INT3922 Negative_regulation of Pnmt 29 0.59 3.18 8.96
150 INT35366 Binding of AR 87 0.47 30.52 8.9
151 INT66213 Localization of RELA 63 0.78 14.71 8.77
152 INT146991 Positive_regulation of Gene_expression of Tlr4 21 0.69 20.76 8.69
153 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68
154 INT7663 Positive_regulation of Pck1 15 0.67 3.05 8.63
155 INT48761 Transcription of Gal 13 0.69 8.53 8.61
156 INT82082 Localization of Lep 63 0.81 26.41 8.56
157 INT75907 Binding of LEP 53 0.46 46.65 8.44
158 INT70896 Gene_expression of PDGFB 48 0.65 33.55 8.39
159 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37
160 INT4867 Positive_regulation of Gene_expression of GAL 17 0.70 6.65 8.28
161 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27
162 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94
163 INT64449 Negative_regulation of Gene_expression of Mc4r 7 0.58 2 7.86
164 INT6856 Gene_expression of Cckbr 10 0.77 1.8 7.69
165 INT6055 Transcription of Egr1 47 0.69 3.61 7.68
166 INT51062 Negative_regulation of Cckbr 7 0.59 1.98 7.68
167 INT181817 Negative_regulation of Gene_expression of Ppara 58 0.58 43.24 7.67
168 INT29142 Positive_regulation of Binding of Pck1 10 0.67 1.48 7.6
169 INT66318 Gene_expression of NR3C1 26 0.76 20 7.55
170 INT103289 Binding of Il10 15 0.35 13.67 7.42
171 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41
172 INT89589 Negative_regulation of Ccl5 9 0.40 4.62 7.39
173 INT30920 Positive_regulation of Gene_expression of Insr 14 0.66 2.91 7.32
174 INT6210 Binding of Nppa 39 0.47 14.35 7.21
175 INT6057 Negative_regulation of Gene_expression of Egr1 17 0.57 4.17 7.17
176 INT90715 Gene_expression of Egr2 12 0.73 1.64 7.17
177 INT91906 Regulation of Gene_expression of Il10 13 0.58 8.92 7.06
178 INT47707 Negative_regulation of Egr1 9 0.41 0.17 7.03
179 INT15156 Positive_regulation of Localization of NPPA 21 0.70 8.61 6.97
180 INT138799 Regulation of Gene_expression of Ppara 40 0.60 29.42 6.89
181 INT24622 Positive_regulation of Localization of Insr 15 0.69 0.32 6.85
182 INT23132 Positive_regulation of Pnmt 17 0.67 2.02 6.84
183 INT295467 Negative_regulation of Gene_expression of Tlr4 11 0.58 7.94 6.83
184 INT6565 Positive_regulation of Positive_regulation of Nppa 14 0.70 4.04 6.76
185 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71
186 INT170922 Binding of Ppara 59 0.45 28.45 6.7
187 INT31705 Gene_expression of Fads1 12 0.22 1.43 6.69
188 INT84685 Regulation of BCL2 67 0.60 72.96 6.65
189 INT50387 Negative_regulation of AR 67 0.45 26.31 6.61
190 INT194479 Phosphorylation of Ppara 47 0.81 30.36 6.6
191 INT517 Regulation of Mif 16 0.62 5.43 6.55
192 INT73022 Positive_regulation of Gene_expression of EGR1 21 0.69 10.61 6.5
193 INT64444 Negative_regulation of Mc4r 9 0.58 5.12 6.44
194 INT60527 Transcription of IL10 16 0.56 13.57 6.42
195 INT5860 Regulation of Gene_expression of Egr1 20 0.62 3.02 6.38
196 INT50328 Positive_regulation of Vgf 8 0.70 13.98 6.37
197 INT7564 Positive_regulation of Nr3c1 16 0.68 4.98 6.25
198 INT55034 Positive_regulation of Adm 27 0.61 14.1 6.13
199 INT516 Negative_regulation of Mif 13 0.59 6.69 6.08
200 INT25193 Negative_regulation of Pck1 20 0.57 5.66 6.05
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