GO:0034136

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Name negative regulation of toll-like receptor 2 signaling pathway
Categary Process
Go Slim No
Go Link GO:0034136
Unique Molecular Interactions 22
Total Molecular Interactions 23
Total Single Events 93
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of toll-like receptor 2 signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of toll-like receptor 2 signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT149386 Binding of Lyn and TRPV4 1 0.40 1.14 0.91
2 INT263978 Binding of ADRB2 and TNFAIP3 1 0.01 0.5 0.32
3 INT204791 Binding of Spg7 and Nod2 1 0.03 0.5 0.16
4 INT204789 Binding of Tlr2 and Nod2 1 0.23 0.44 0.16
5 INT145830 Mdp1 Positive_regulation of Nod2 1 0.34 0.52 0.13
6 INT129091 Binding of PIK3CG and Lyn 1 0.00 0.47 0.12
7 INT129075 Binding of Pik3r1 and Lyn 1 0.00 0.47 0.12
8 INT129093 Binding of Lyn and TCHP 1 0.00 0.49 0.12
9 INT129092 Binding of GRP and Lyn 1 0.00 0.48 0.12
10 INT200814 Epo Positive_regulation of Lyn 1 0.36 1.42 0.03
11 INT278388 Msu Positive_regulation of Phosphorylation of Lyn 1 0.17 0.12 0
12 INT261838 Lyn Regulation of Trpv4 1 0.03 0.19 0
13 INT261843 Lyn Regulation of Regulation of Trpv4 1 0.03 0.19 0
14 INT347226 Hck Regulation of Gene_expression of Lyn 1 0.10 0.08 0
15 INT241539 Binding of Abl1 and Lyn 1 0.09 0.14 0
16 INT200818 Akt1 Positive_regulation of Negative_regulation of Lyn 1 0.25 1.02 0
17 INT241538 Negative_regulation of Binding of Abl1 and Lyn 1 0.11 0.14 0
18 INT347224 Lyn Regulation of Positive_regulation of Bcr 1 0.14 0.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of toll-like receptor 2 signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of toll-like receptor 2 signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT146946 Gene_expression of Lyn 16 0.76 8.9 3.75
2 INT146945 Positive_regulation of Lyn 6 0.49 2.81 2.25
3 INT204766 Gene_expression of Nod2 4 0.75 4.14 1.3
4 INT136574 Regulation of TNFAIP3 2 0.11 1.33 1.3
5 INT274898 Positive_regulation of Positive_regulation of Lyn 1 0.35 1.51 1.05
6 INT146939 Negative_regulation of Lyn 3 0.53 2.97 0.95
7 INT156976 Gene_expression of TNFAIP3 4 0.65 5.25 0.93
8 INT149383 Binding of Lyn 1 0.36 1.14 0.91
9 INT347182 Negative_regulation of TNFAIP3 3 0.23 5.6 0.84
10 INT264003 Positive_regulation of Transcription of TNFAIP3 1 0.38 1.01 0.65
11 INT263996 Transcription of TNFAIP3 1 0.39 0.99 0.64
12 INT117091 Positive_regulation of Lyn 1 0.49 0.41 0.56
13 INT204781 Positive_regulation of Nod2 6 0.45 2.79 0.46
14 INT346895 Positive_regulation of Gene_expression of Nod2 1 0.33 0.74 0.28
15 INT346896 Binding of Nod2 1 0.21 0.72 0.26
16 INT346899 Regulation of Positive_regulation of Nod2 1 0.18 0.75 0.22
17 INT261820 Phosphorylation of Lyn 5 0.30 1.41 0.2
18 INT304142 Negative_regulation of Phosphorylation of Lyn 1 0.12 1.11 0.2
19 INT278361 Positive_regulation of Gene_expression of Lyn 6 0.41 0.63 0.15
20 INT304452 Regulation of Lyn 1 0.17 0 0.15
21 INT204777 Negative_regulation of Localization of Nod2 1 0.28 0.61 0.09
22 INT204779 Localization of Nod2 1 0.48 0.6 0.08
23 INT204770 Regulation of Nod2 1 0.29 0.66 0.07
24 INT241509 Negative_regulation of Gene_expression of Lyn 2 0.20 1.02 0.05
25 INT315847 Positive_regulation of Negative_regulation of Lyn 1 0.18 0.61 0.05
26 INT346893 Negative_regulation of Gene_expression of Nod2 1 0.28 0.13 0.04
27 INT217333 Positive_regulation of TNFAIP3 3 0.23 2.65 0
28 INT348456 Protein_catabolism of TNFAIP3 1 0.22 1.13 0
29 INT348453 Positive_regulation of Positive_regulation of TNFAIP3 1 0.17 1.06 0
30 INT284053 Positive_regulation of Positive_regulation of Nod2 1 0.25 0.08 0
31 INT278323 Positive_regulation of Phosphorylation of Lyn 1 0.22 0 0
32 INT278322 Negative_regulation of Localization of Lyn 1 0.20 0.11 0
33 INT278356 Localization of Lyn 1 0.35 0.11 0
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