GO:0035257

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Name nuclear hormone receptor binding
Categary Function
Go Slim No
Go Link GO:0035257
Unique Molecular Interactions 73
Total Molecular Interactions 88
Total Single Events 433
Pain Genes Associated 13

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for nuclear hormone receptor binding. They are ordered first by their pain relevance and then by number of times they were reported for nuclear hormone receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT114948 NCOA1 Positive_regulation of Positive_regulation of PPARA 1 0.20 0.24 0.62
2 INT114949 NCOA1 Positive_regulation of Gene_expression of RXRA 1 0.13 0.24 0.61
3 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
4 INT124378 Prodh2 Positive_regulation of Ctnnb1 1 0.00 0.59 0.35
5 INT120236 Binding of Ncoa1 and Insrr 1 0.00 0.15 0.28
6 INT120237 Positive_regulation of Binding of Ncoa1 and Insrr 1 0.00 0.15 0.28
7 INT186783 Binding of ESR1 and NRIP1 1 0.31 0.79 0.25
8 INT186782 Binding of RARB and NRIP1 1 0.03 0.49 0.2
9 INT186781 Binding of NRIP1 and GOPC 1 0.05 0.49 0.2
10 INT245183 Binding of CTSB and TCF7L2 1 0.39 6.39 0.18
11 INT201865 Binding of PGR and NCOA1 1 0.03 0 0.17
12 INT251115 Positive_regulation of Binding of AR and Ctnnb1 1 0.01 1.02 0.13
13 INT262185 Positive_regulation of Binding of Ncoa1 and Nr1i2 1 0.04 0.56 0.12
14 INT251114 Binding of AR and Ctnnb1 1 0.01 1 0.12
15 INT262146 Binding of Ncoa1 and Nr1i2 1 0.03 0.56 0.11
16 INT245185 Binding of RRAD and TCF7L2 1 0.00 6.88 0.1
17 INT245182 Binding of SPINK1 and TCF7L2 1 0.39 2.05 0.1
18 INT110377 Binding of Ncoa1 and Pparg 1 0.02 0.26 0.08
19 INT225490 Med1 Positive_regulation of Ppara 1 0.12 0.26 0.06
20 INT56278 Binding of CYP2B6 and TACC2 1 0.40 0.32 0.06
21 INT236596 Ncoa2 Positive_regulation of PELP1 1 0.36 0.17 0.04
22 INT261393 Binding of Nsdhl and Med1 1 0.02 1 0.04
23 INT236149 Binding of Ncoa1 and Ppara 1 0.07 0 0.03
24 INT236586 Binding of Ncoa2 and Psmd4 1 0.12 0.22 0.03
25 INT236590 Binding of Adipoq and Ncoa2 1 0.15 0.2 0.03
26 INT236597 Ncoa1 Positive_regulation of PELP1 1 0.41 0.17 0.03
27 INT236587 Binding of Adipoq and Ncoa1 1 0.17 0.2 0.03
28 INT243110 Pprc1 Negative_regulation of Ncoa2 1 0.00 0.52 0.03
29 INT243108 Pprc1 Negative_regulation of Ncoa1 1 0.00 0.53 0.03
30 INT236592 Positive_regulation of Binding of Adipoq and Ncoa2 1 0.19 0.2 0.03
31 INT236585 Ncoa2 Positive_regulation of Transcription of Ncoa1 1 0.27 0.23 0.03
32 INT225585 Regulation of Binding of Med1 and Tpr 1 0.00 0.07 0
33 INT225583 Binding of Ncoa1 and Tpr 1 0.00 0.07 0
34 INT233930 Binding of PPARA and Ncoa1 1 0.12 0.19 0
35 INT177254 Binding of CXADR and NCOA2 1 0.19 0 0
36 INT355603 Binding of CTNNA1 and Ctnnb1 1 0.00 1.07 0
37 INT296954 NRIP1 Negative_regulation of Gene_expression of UCP1 1 0.30 1.05 0
38 INT220818 Binding of Ctnnb1 and Myc 1 0.06 0.13 0
39 INT225520 Binding of Ncoa2 and Ncoa6 1 0.05 0.11 0
40 INT296960 Binding of NRIP1 and MLST8 1 0.03 2.65 0
41 INT286566 Binding of Ctnnb1 and Cdh6 1 0.00 1 0
42 INT286562 Gene_expression of Pkd1 Positive_regulation of Ctnnb1 1 0.02 0.52 0
43 INT177267 Binding of CXADR and NCOA3 1 0.17 0 0
44 INT296956 NRIP1 Regulation of Gene_expression of CIDEA 1 0.44 0.76 0
45 INT136693 Gtf3a Positive_regulation of Ctnnb1 1 0.05 0 0
46 INT308352 Binding of Ctnnd2 and Tcf7l2 1 0.15 0.74 0
47 INT296959 NRIP1 Regulation of SLC2A4 1 0.22 0.54 0
48 INT233928 PPARA Positive_regulation of Localization of Ncoa1 1 0.18 0.19 0
49 INT233927 PPARA Positive_regulation of Ncoa1 1 0.08 0.19 0
50 INT225481 Binding of Med1 and Acp5 1 0.16 0 0
51 INT220821 Binding of MAX and Ctnnb1 1 0.09 0.13 0
52 INT296957 NRIP1 Regulation of Transcription of CIDEA 1 0.44 0.91 0
53 INT177289 Binding of CXADR and NCOA1 1 0.17 0 0
54 INT296958 NRIP1 Regulation of Gene_expression of MLST8 1 0.04 0.76 0
55 INT225571 Binding of Ncoa1 and Tfrc 1 0.01 0 0
56 INT225579 Binding of Ncoa1 and D0Nrs1 1 0.00 0 0
57 INT286561 Binding of Ctnnb1 and Cdh2 1 0.00 1.06 0
58 INT245193 Binding of TCF7L2 and Abpa 1 0.02 10.66 0
59 INT177264 Positive_regulation of Binding of NCOA1 and SV2A 1 0.17 0 0
60 INT286567 Prkd1 Regulation of Ctnnb1 1 0.01 0.39 0
61 INT225541 Binding of Med1 and Tpr 1 0.00 0.07 0
62 INT177271 Binding of NCOA1 and SV2A 1 0.17 0 0
63 INT307208 Binding of Ppara and Nrip1 1 0.34 0.31 0
64 INT318806 Binding of VEGFA and NCOA1 1 0.00 0.22 0
65 INT286572 Binding of Ctnnb1 and Pkd1 1 0.02 0.96 0
66 INT182933 Binding of NCOA2 and GSTK1 1 0.01 0.08 0
67 INT277368 Regulation of TFAM Positive_regulation of Gene_expression of TCF7L2 1 0.01 0.9 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for nuclear hormone receptor binding. They are ordered first by their pain relevance and then by number of times they were reported in nuclear hormone receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT67248 Gene_expression of TACC2 12 0.50 13.51 3.65
2 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
3 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
4 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
5 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
6 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
7 INT120664 Positive_regulation of TACC2 3 0.01 7.43 1.08
8 INT101570 Positive_regulation of Gene_expression of Ctnnb1 1 0.58 5.7 1.07
9 INT101566 Negative_regulation of Gene_expression of Ctnnb1 1 0.35 2.28 0.88
10 INT186790 Regulation of NRIP1 4 0.45 6.68 0.64
11 INT99390 Regulation of Ctnnb1 4 0.62 3.12 0.64
12 INT236571 Transcription of Ncoa1 2 0.50 0.17 0.64
13 INT114954 Positive_regulation of Gene_expression of NCOA1 1 0.19 0.24 0.61
14 INT114958 Gene_expression of NCOA1 2 0.41 0.24 0.6
15 INT76960 Negative_regulation of Ctnnb1 5 0.57 3.46 0.53
16 INT48163 Localization of TACC2 1 0.06 0.32 0.53
17 INT81645 Positive_regulation of Gene_expression of Ctnnb1 6 0.63 3.78 0.47
18 INT120665 Binding of TACC2 4 0.07 4.33 0.46
19 INT120229 Binding of Ncoa1 6 0.35 1.04 0.44
20 INT186786 Positive_regulation of NRIP1 3 0.50 4.81 0.42
21 INT76958 Positive_regulation of Ctnnb1 14 0.64 5.48 0.41
22 INT225367 Gene_expression of Ncoa2 9 0.65 2.71 0.4
23 INT95872 Localization of Ctnnb1 7 0.74 2.75 0.4
24 INT145045 Gene_expression of Med1 29 0.65 5.37 0.39
25 INT296969 Gene_expression of NRIP1 1 0.78 26.23 0.38
26 INT81644 Regulation of Ctnnb1 5 0.41 3.38 0.37
27 INT81643 Regulation of Gene_expression of Ctnnb1 3 0.57 1.5 0.37
28 INT108324 Negative_regulation of Gene_expression of Ctnnb1 1 0.06 1.43 0.31
29 INT124588 Gene_expression of Ncoa1 9 0.49 2.38 0.27
30 INT151719 Negative_regulation of Positive_regulation of Ctnnb1 1 0.23 1.9 0.24
31 INT105327 Positive_regulation of Ncoa2 3 0.06 1.85 0.21
32 INT242393 Positive_regulation of Positive_regulation of Ncoa2 1 0.02 1.17 0.21
33 INT186784 Positive_regulation of Nrip1 1 0.39 1.1 0.21
34 INT236584 Regulation of Ncoa1 2 0.33 1.82 0.2
35 INT114371 Negative_regulation of Tcf7l2 1 0.05 0.7 0.2
36 INT213914 Positive_regulation of NCOA3 1 0.44 1.34 0.2
37 INT294482 Negative_regulation of Gene_expression of Ncoa2 1 0.01 1.77 0.18
38 INT99392 Negative_regulation of Localization of Ctnnb1 2 0.59 1.43 0.17
39 INT151721 Negative_regulation of Localization of Ctnnb1 1 0.23 0.96 0.17
40 INT325506 Positive_regulation of Localization of Ctnnb1 1 0.05 0.28 0.17
41 INT242391 Negative_regulation of Ncoa2 1 0.02 1.21 0.16
42 INT213912 Positive_regulation of Gene_expression of NCOA3 1 0.44 1.06 0.15
43 INT245190 Binding of TCF7L2 6 0.48 12.29 0.13
44 INT130374 Transcription of Ctnnb1 1 0.19 0 0.13
45 INT236575 Regulation of Ncoa2 1 0.29 0.72 0.11
46 INT213913 Gene_expression of NCOA3 3 0.50 1.11 0.1
47 INT201994 Regulation of TACC2 2 0.03 0.21 0.1
48 INT213911 Positive_regulation of Positive_regulation of NCOA3 1 0.32 0.67 0.1
49 INT338007 Regulation of NCOA2 1 0.26 1.1 0.09
50 INT107960 Positive_regulation of Ncoa1 3 0.37 1.59 0.08
51 INT245191 Positive_regulation of TCF7L2 2 0.46 1.54 0.07
52 INT236561 Positive_regulation of Gene_expression of Ncoa2 3 0.49 0.48 0.06
53 INT233912 Localization of Ncoa1 4 0.73 0.53 0.05
54 INT236137 Positive_regulation of Localization of Ncoa1 3 0.10 0.34 0.05
55 INT172624 Binding of NCOA3 4 0.22 1.05 0.03
56 INT296973 Regulation of Gene_expression of NRIP1 1 0.45 2.2 0.03
57 INT236557 Transcription of Ncoa2 1 0.44 0.23 0.03
58 INT296996 Negative_regulation of NRIP1 1 0.59 14.18 0.03
59 INT236574 Binding of Ncoa2 1 0.31 0.21 0.03
60 INT171516 Gene_expression of NCOA2 4 0.25 0.63 0
61 INT177319 Binding of NCOA1 3 0.12 0.31 0
62 INT307182 Gene_expression of Nrip1 3 0.58 1.06 0
63 INT307189 Localization of Med1 3 0.53 0.32 0
64 INT225400 Positive_regulation of Gene_expression of Med1 2 0.35 0.82 0
65 INT76959 Binding of Ctnnb1 2 0.34 0.69 0
66 INT177333 Binding of NCOA2 2 0.14 0.07 0
67 INT210256 Positive_regulation of Tcf7l2 2 0.28 1.25 0
68 INT307200 Negative_regulation of Nrip1 2 0.41 1.72 0
69 INT225358 Negative_regulation of Gene_expression of Med1 2 0.30 1.16 0
70 INT277402 Gene_expression of TCF7L2 1 0.48 1.67 0
71 INT307197 Negative_regulation of Med1 1 0.30 0.7 0
72 INT230651 Phosphorylation of Ctnnb1 1 0.10 0 0
73 INT230674 Positive_regulation of Phosphorylation of Ctnnb1 1 0.06 0 0
74 INT296994 Negative_regulation of Negative_regulation of NRIP1 1 0.43 1.18 0
75 INT326137 Protein_catabolism of Ctnnb1 1 0.02 1.08 0
76 INT307188 Transcription of Med1 1 0.48 0.7 0
77 INT300368 Regulation of TCF7L2 1 0.15 2.43 0
78 INT355576 Negative_regulation of Negative_regulation of Ctnnb1 1 0.02 1.14 0
79 INT233918 Localization of NCOA2 1 0.08 0.37 0
80 INT296989 Negative_regulation of Gene_expression of NRIP1 1 0.43 0 0
81 INT307187 Negative_regulation of Ncoa1 1 0.08 0.11 0
82 INT296997 Positive_regulation of Gene_expression of NRIP1 1 0.70 5.77 0
83 INT307180 Positive_regulation of Localization of Ncoa2 1 0.06 0.28 0
84 INT225389 Regulation of Binding of Med1 1 0.17 0.07 0
85 INT220769 Positive_regulation of Positive_regulation of Ctnnb1 1 0.10 0 0
86 INT296987 Positive_regulation of Negative_regulation of NRIP1 1 0.50 0.73 0
87 INT297363 Localization of NCOA1 1 0.05 0.06 0
88 INT225457 Binding of Med1 1 0.35 0.28 0
89 INT296977 Binding of NRIP1 1 0.37 1.37 0
90 INT225450 Negative_regulation of Gene_expression of Ncoa1 1 0.06 0.97 0
91 INT225336 Regulation of Binding of Ncoa1 1 0.06 0.07 0
92 INT334482 Regulation of Gene_expression of Med1 1 0.17 0.1 0
93 INT307181 Localization of Ncoa2 1 0.10 0.28 0
94 INT277384 Transcription of TCF7L2 1 0.55 0.82 0
95 INT236556 Positive_regulation of Gene_expression of Ncoa1 1 0.37 0.36 0
96 INT334481 Negative_regulation of Localization of Med1 1 0.16 0.09 0
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