GO:0035315

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Name hair cell differentiation
Categary Process
Go Slim No
Go Link GO:0035315
Unique Molecular Interactions 21
Total Molecular Interactions 36
Total Single Events 122
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for hair cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for hair cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT266102 Binding of PITX2 and RS1 1 0.00 0.64 0.8
2 INT122823 ERCC2 Regulation of Negative_regulation of OPRM1 1 0.23 0.17 0.63
3 INT142947 Binding of ERCC2 and OPRM1 1 0.05 0.3 0.32
4 INT229635 SPINK5 Positive_regulation of NF1 1 0.01 2.17 0.3
5 INT149096 PITX2 Positive_regulation of Gene_expression of Egr1 1 0.01 1.23 0.19
6 INT341818 Binding of PITX2 and Aia1 1 0.00 0.53 0.16
7 INT149095 PITX2 Positive_regulation of Casp3 1 0.00 1.51 0.15
8 INT149092 PITX2 Positive_regulation of RFFL 1 0.00 1.51 0.15
9 INT103557 Binding of ERCC2 and TP53 1 0.40 1 0.13
10 INT339047 Binding of PITX2 and SNRNP70 1 0.00 0.52 0
11 INT339043 SNRNP70 Regulation of PITX2 1 0.00 1.42 0
12 INT250557 Binding of PITX2 and CHDH 1 0.00 2.83 0
13 INT339044 Binding of PITX2 and SUGT1 1 0.00 2.25 0
14 INT354309 Binding of MYC and PITX2 1 0.01 0.51 0
15 INT149429 ERCC2 Negative_regulation of Localization of IL8 1 0.05 0.38 0
16 INT227840 Binding of ERCC2 and ERCC6 1 0.11 0.66 0
17 INT339049 Binding of PITX2 and RENBP 1 0.00 0.27 0
18 INT149431 ERCC2 Negative_regulation of Localization of Il6 1 0.14 0.2 0
19 INT227831 Binding of ERCC2 and PGBD3 1 0.07 0.23 0
20 INT149432 ERCC2 Regulation of Localization of Il6 1 0.15 1.06 0
21 INT149428 ERCC2 Regulation of Localization of IL8 1 0.05 0.53 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for hair cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in hair cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT103899 Gene_expression of ERCC2 14 0.65 7.85 5.49
2 INT138872 Gene_expression of SPINK5 21 0.58 30.11 4.12
3 INT108793 Gene_expression of PITX2 12 0.75 3.91 2.89
4 INT103900 Positive_regulation of ERCC2 7 0.58 3.47 1.78
5 INT219879 Positive_regulation of SPINK5 4 0.30 7.64 1.16
6 INT100154 Regulation of PITX2 5 0.60 0.48 1.15
7 INT142950 Protein_catabolism of ERCC2 2 0.25 1.45 1.14
8 INT108795 Transcription of PITX2 1 0.69 0.46 0.96
9 INT138980 Binding of PITX2 15 0.47 10.34 0.88
10 INT152437 Localization of SPINK5 4 0.54 3.97 0.69
11 INT303669 Regulation of SPINK5 1 0.24 0.65 0.53
12 INT134070 Binding of ERCC2 3 0.27 0.76 0.51
13 INT103901 Regulation of ERCC2 1 0.23 0.51 0.4
14 INT158764 Binding of SPINK5 7 0.35 8.84 0.37
15 INT166727 Regulation of Gene_expression of PITX2 1 0.60 0.09 0.26
16 INT149094 Positive_regulation of Gene_expression of PITX2 1 0.05 1.23 0.19
17 INT158767 Negative_regulation of SPINK5 1 0.31 0.45 0.09
18 INT200136 Negative_regulation of ERCC2 1 0.37 1.91 0.07
19 INT246361 Positive_regulation of Gene_expression of SPINK5 1 0.07 2.55 0.06
20 INT262962 Localization of PITX2 1 0.42 0.64 0.06
21 INT356474 Negative_regulation of PITX2 1 0.03 0.07 0.04
22 INT291906 Positive_regulation of Negative_regulation of ERCC2 1 0.40 0 0.03
23 INT250574 Positive_regulation of PITX2 2 0.02 1.79 0
24 INT149430 Localization of ERCC2 1 0.43 0.76 0
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