GO:0035357

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Name peroxisome proliferator activated receptor signaling pathway
Categary Process
Go Slim No
Go Link GO:0035357
Unique Molecular Interactions 37
Total Molecular Interactions 71
Total Single Events 316
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for peroxisome proliferator activated receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for peroxisome proliferator activated receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT202620 Binding of Ppara and Rxra 15 0.09 2.63 1.11
2 INT128859 Positive_regulation of RXRA Regulation of Gene_expression of OPRM1 1 0.05 0.26 0.9
3 INT114947 YY1 Positive_regulation of Gene_expression of RXRA 1 0.33 0.25 0.65
4 INT114951 PPARA Positive_regulation of Gene_expression of RXRA 1 0.34 0.25 0.64
5 INT114949 NCOA1 Positive_regulation of Gene_expression of RXRA 1 0.13 0.24 0.61
6 INT333453 Binding of PPARA and RXRA 1 0.02 0 0.31
7 INT297376 Binding of RARS and Rxra 1 0.01 3.27 0.24
8 INT312550 DAK Positive_regulation of Rxra 1 0.00 1.48 0.18
9 INT313023 Binding of Rara and Rxra 1 0.06 0.73 0.17
10 INT333447 Binding of SMAD2 and RXRA 1 0.04 0 0.16
11 INT156833 Binding of MED1 and TRPV6 1 0.32 0 0.15
12 INT156837 Binding of CYP24A1 and MED1 1 0.47 0 0.15
13 INT166724 Binding of Vdr and Rxra 1 0.28 0.32 0.09
14 INT278684 Binding of NR1I3 and Rxra 1 0.00 0 0.07
15 INT236932 Binding of Rxra and Pprc1 1 0.00 0.45 0.07
16 INT278685 Binding of CASR and Rxra 1 0.00 0 0.07
17 INT225490 Med1 Positive_regulation of Ppara 1 0.12 0.26 0.06
18 INT285384 Binding of Rare1 and Rxra 1 0.01 0.08 0.05
19 INT307218 Binding of Rxra and D0Nrs1 1 0.00 0.1 0.05
20 INT261393 Binding of Nsdhl and Med1 1 0.02 1 0.04
21 INT291714 Binding of RARA and Rxra 3 0.07 0.2 0.03
22 INT297377 Binding of PPARA and Rxra 1 0.02 0.25 0.03
23 INT297375 Binding of VDR and Rxra 1 0.02 0.2 0.03
24 INT297374 Binding of TXNRD1 and Rxra 1 0.01 0.2 0.03
25 INT225585 Regulation of Binding of Med1 and Tpr 1 0.00 0.07 0
26 INT177262 Binding of MED1 and SV2A 1 0.23 0 0
27 INT291715 Binding of DR1 and Rxra 1 0.09 0 0
28 INT291716 Binding of SOD1 and Rxra 1 0.21 0 0
29 INT236719 Binding of Dr1 and Rxra 1 0.01 0 0
30 INT225481 Binding of Med1 and Acp5 1 0.16 0 0
31 INT177286 Binding of CXADR and MED1 1 0.27 0 0
32 INT291712 Binding of Rxra and SPNS1 1 0.04 0 0
33 INT225541 Binding of Med1 and Tpr 1 0.00 0.07 0
34 INT291711 Rxra Positive_regulation of VDR 1 0.09 0 0
35 INT291713 Binding of TNFRSF10B and Rxra 1 0.05 0 0
36 INT177280 Binding of MED1 and FAUP1 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for peroxisome proliferator activated receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in peroxisome proliferator activated receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT114274 Gene_expression of Rxra 67 0.70 36.77 12.5
2 INT181186 Binding of Rxra 78 0.35 14.93 4.87
3 INT130080 Negative_regulation of Rxra 6 0.53 2.08 2.92
4 INT169318 Positive_regulation of Rxra 15 0.42 4.35 2.12
5 INT130082 Regulation of Rxra 6 0.42 3.78 1.96
6 INT199724 Positive_regulation of Gene_expression of Rxra 11 0.45 6.22 1.88
7 INT128865 Regulation of Positive_regulation of RXRA 1 0.08 0.64 1.48
8 INT128863 Positive_regulation of RXRA 1 0.12 0.63 1.47
9 INT114959 Gene_expression of RXRA 2 0.50 1.06 0.63
10 INT114960 Positive_regulation of Gene_expression of RXRA 1 0.32 0.24 0.61
11 INT199723 Localization of Rxra 8 0.59 1.31 0.58
12 INT114277 Regulation of Gene_expression of Rxra 1 0.28 0.75 0.58
13 INT145045 Gene_expression of Med1 29 0.65 5.37 0.39
14 INT233917 Gene_expression of MED1 2 0.20 0.17 0.38
15 INT285391 Binding of RXRA 2 0.03 0.08 0.36
16 INT199725 Negative_regulation of Gene_expression of Rxra 2 0.38 0.3 0.3
17 INT106734 Phosphorylation of MED1 4 0.74 1.65 0.28
18 INT236564 Positive_regulation of Binding of Rxra 2 0.18 1.3 0.24
19 INT206946 Gene_expression of Rxra 4 0.60 2.2 0.17
20 INT106730 Regulation of Phosphorylation of MED1 2 0.24 0.7 0.16
21 INT106731 Negative_regulation of Phosphorylation of MED1 1 0.02 0.96 0.12
22 INT332915 Positive_regulation of Localization of Rxra 1 0.03 0.3 0.11
23 INT214072 Regulation of Gene_expression of RXRA 1 0.01 0.83 0.09
24 INT166719 Positive_regulation of Rxra 1 0.36 0.31 0.09
25 INT156864 Positive_regulation of Phosphorylation of MED1 1 0.45 0 0.07
26 INT256518 Positive_regulation of Transcription of Rxra 1 0.04 0.24 0.06
27 INT291692 Regulation of Binding of Rxra 4 0.32 0.57 0.05
28 INT225406 Transcription of Rxra 3 0.41 0.33 0.03
29 INT256507 Regulation of Transcription of Rxra 1 0.04 0.12 0.03
30 INT291693 Negative_regulation of Binding of Rxra 1 0.22 0.07 0.03
31 INT307189 Localization of Med1 3 0.53 0.32 0
32 INT225400 Positive_regulation of Gene_expression of Med1 2 0.35 0.82 0
33 INT225358 Negative_regulation of Gene_expression of Med1 2 0.30 1.16 0
34 INT177336 Positive_regulation of Binding of MED1 1 0.24 0 0
35 INT307197 Negative_regulation of Med1 1 0.30 0.7 0
36 INT307188 Transcription of Med1 1 0.48 0.7 0
37 INT231922 Negative_regulation of Positive_regulation of Rxra 1 0.06 0.33 0
38 INT225389 Regulation of Binding of Med1 1 0.17 0.07 0
39 INT177320 Binding of MED1 1 0.25 0 0
40 INT225457 Binding of Med1 1 0.35 0.28 0
41 INT346487 Negative_regulation of Phosphorylation of RXRA 1 0.01 0.63 0
42 INT291694 Negative_regulation of Localization of Rxra 1 0.22 0 0
43 INT341851 Positive_regulation of MED1 1 0.01 0.5 0
44 INT291695 Regulation of Negative_regulation of Rxra 1 0.23 0.14 0
45 INT346494 Phosphorylation of RXRA 1 0.01 0.63 0
46 INT334482 Regulation of Gene_expression of Med1 1 0.17 0.1 0
47 INT291698 Negative_regulation of Negative_regulation of Rxra 1 0.22 0 0
48 INT334481 Negative_regulation of Localization of Med1 1 0.16 0.09 0
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