GO:0035357

Name peroxisome proliferator activated receptor signaling pathway Categary Process Go Slim No Go Link GO:0035357

Unique Molecular Interactions 37 Total Molecular Interactions 71 Total Single Events 316 Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for peroxisome proliferator activated receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for peroxisome proliferator activated receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT202620	Binding of Ppara and Rxra	15	0.09	2.63	1.11
2	INT128859	Positive_regulation of RXRA Regulation of Gene_expression of OPRM1	1	0.05	0.26	0.9
3	INT114947	YY1 Positive_regulation of Gene_expression of RXRA	1	0.33	0.25	0.65
4	INT114951	PPARA Positive_regulation of Gene_expression of RXRA	1	0.34	0.25	0.64
5	INT114949	NCOA1 Positive_regulation of Gene_expression of RXRA	1	0.13	0.24	0.61
6	INT333453	Binding of PPARA and RXRA	1	0.02	0	0.31
7	INT297376	Binding of RARS and Rxra	1	0.01	3.27	0.24
8	INT312550	DAK Positive_regulation of Rxra	1	0.00	1.48	0.18
9	INT313023	Binding of Rara and Rxra	1	0.06	0.73	0.17
10	INT333447	Binding of SMAD2 and RXRA	1	0.04	0	0.16
11	INT156833	Binding of MED1 and TRPV6	1	0.32	0	0.15
12	INT156837	Binding of CYP24A1 and MED1	1	0.47	0	0.15
13	INT166724	Binding of Vdr and Rxra	1	0.28	0.32	0.09
14	INT278684	Binding of NR1I3 and Rxra	1	0.00	0	0.07
15	INT236932	Binding of Rxra and Pprc1	1	0.00	0.45	0.07
16	INT278685	Binding of CASR and Rxra	1	0.00	0	0.07
17	INT225490	Med1 Positive_regulation of Ppara	1	0.12	0.26	0.06
18	INT285384	Binding of Rare1 and Rxra	1	0.01	0.08	0.05
19	INT307218	Binding of Rxra and D0Nrs1	1	0.00	0.1	0.05
20	INT261393	Binding of Nsdhl and Med1	1	0.02	1	0.04
21	INT291714	Binding of RARA and Rxra	3	0.07	0.2	0.03
22	INT297377	Binding of PPARA and Rxra	1	0.02	0.25	0.03
23	INT297375	Binding of VDR and Rxra	1	0.02	0.2	0.03
24	INT297374	Binding of TXNRD1 and Rxra	1	0.01	0.2	0.03
25	INT225585	Regulation of Binding of Med1 and Tpr	1	0.00	0.07	0
26	INT177262	Binding of MED1 and SV2A	1	0.23	0	0
27	INT291715	Binding of DR1 and Rxra	1	0.09	0	0
28	INT291716	Binding of SOD1 and Rxra	1	0.21	0	0
29	INT236719	Binding of Dr1 and Rxra	1	0.01	0	0
30	INT225481	Binding of Med1 and Acp5	1	0.16	0	0
31	INT177286	Binding of CXADR and MED1	1	0.27	0	0
32	INT291712	Binding of Rxra and SPNS1	1	0.04	0	0
33	INT225541	Binding of Med1 and Tpr	1	0.00	0.07	0
34	INT291711	Rxra Positive_regulation of VDR	1	0.09	0	0
35	INT291713	Binding of TNFRSF10B and Rxra	1	0.05	0	0
36	INT177280	Binding of MED1 and FAUP1	1	0.01	0	0

Single Events

The table below shows the top 100 pain related interactions that have been reported for peroxisome proliferator activated receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in peroxisome proliferator activated receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT114274	Gene_expression of Rxra	67	0.70	36.77	12.5
2	INT181186	Binding of Rxra	78	0.35	14.93	4.87
3	INT130080	Negative_regulation of Rxra	6	0.53	2.08	2.92
4	INT169318	Positive_regulation of Rxra	15	0.42	4.35	2.12
5	INT130082	Regulation of Rxra	6	0.42	3.78	1.96
6	INT199724	Positive_regulation of Gene_expression of Rxra	11	0.45	6.22	1.88
7	INT128865	Regulation of Positive_regulation of RXRA	1	0.08	0.64	1.48
8	INT128863	Positive_regulation of RXRA	1	0.12	0.63	1.47
9	INT114959	Gene_expression of RXRA	2	0.50	1.06	0.63
10	INT114960	Positive_regulation of Gene_expression of RXRA	1	0.32	0.24	0.61
11	INT199723	Localization of Rxra	8	0.59	1.31	0.58
12	INT114277	Regulation of Gene_expression of Rxra	1	0.28	0.75	0.58
13	INT145045	Gene_expression of Med1	29	0.65	5.37	0.39
14	INT233917	Gene_expression of MED1	2	0.20	0.17	0.38
15	INT285391	Binding of RXRA	2	0.03	0.08	0.36
16	INT199725	Negative_regulation of Gene_expression of Rxra	2	0.38	0.3	0.3
17	INT106734	Phosphorylation of MED1	4	0.74	1.65	0.28
18	INT236564	Positive_regulation of Binding of Rxra	2	0.18	1.3	0.24
19	INT206946	Gene_expression of Rxra	4	0.60	2.2	0.17
20	INT106730	Regulation of Phosphorylation of MED1	2	0.24	0.7	0.16
21	INT106731	Negative_regulation of Phosphorylation of MED1	1	0.02	0.96	0.12
22	INT332915	Positive_regulation of Localization of Rxra	1	0.03	0.3	0.11
23	INT214072	Regulation of Gene_expression of RXRA	1	0.01	0.83	0.09
24	INT166719	Positive_regulation of Rxra	1	0.36	0.31	0.09
25	INT156864	Positive_regulation of Phosphorylation of MED1	1	0.45	0	0.07
26	INT256518	Positive_regulation of Transcription of Rxra	1	0.04	0.24	0.06
27	INT291692	Regulation of Binding of Rxra	4	0.32	0.57	0.05
28	INT225406	Transcription of Rxra	3	0.41	0.33	0.03
29	INT256507	Regulation of Transcription of Rxra	1	0.04	0.12	0.03
30	INT291693	Negative_regulation of Binding of Rxra	1	0.22	0.07	0.03
31	INT307189	Localization of Med1	3	0.53	0.32	0
32	INT225400	Positive_regulation of Gene_expression of Med1	2	0.35	0.82	0
33	INT225358	Negative_regulation of Gene_expression of Med1	2	0.30	1.16	0
34	INT177336	Positive_regulation of Binding of MED1	1	0.24	0	0
35	INT307197	Negative_regulation of Med1	1	0.30	0.7	0
36	INT307188	Transcription of Med1	1	0.48	0.7	0
37	INT231922	Negative_regulation of Positive_regulation of Rxra	1	0.06	0.33	0
38	INT225389	Regulation of Binding of Med1	1	0.17	0.07	0
39	INT177320	Binding of MED1	1	0.25	0	0
40	INT225457	Binding of Med1	1	0.35	0.28	0
41	INT346487	Negative_regulation of Phosphorylation of RXRA	1	0.01	0.63	0
42	INT291694	Negative_regulation of Localization of Rxra	1	0.22	0	0
43	INT341851	Positive_regulation of MED1	1	0.01	0.5	0
44	INT291695	Regulation of Negative_regulation of Rxra	1	0.23	0.14	0
45	INT346494	Phosphorylation of RXRA	1	0.01	0.63	0
46	INT334482	Regulation of Gene_expression of Med1	1	0.17	0.1	0
47	INT291698	Negative_regulation of Negative_regulation of Rxra	1	0.22	0	0
48	INT334481	Negative_regulation of Localization of Med1	1	0.16	0.09	0